Human Polyomaviruses Are Not Frequently Present in Cancer of the Salivary Glands.

abstract：BACKGROUND/AIM:Few studies have examined postoperative CRP in esophageal cancer. We investigated the relationship between postoperative CRP values according to the postoperative period and prognosis in esophageal cancer. PATIENTS AND METHODS:We performed a retrospective cohort study including 187 patients who underwen...

journal_title：Anticancer research

authors： Katsurahara K,Shiozaki A,Fujiwara H,Konishi H,Kudou M,Shoda K,Arita T,Kosuga T,Morimura R,Murayama Y,Kuriu Y,Ikoma H,Kubota T,Nakanishi M,Okamoto K,Otsuji E

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND/AIM:Trans-hiatal and -cervical approach mediastinoscopic radical esophagectomy (TMrE) for esophageal cancers is a less-invasive procedure and does not require for trans-thoracic approach management. However, some patients suffer from pleural effusion after TMrE. In the present study, we investigated the clin...

journal_title：Anticancer research

authors： Hamada J,Konishi H,Shiozaki A,Fujiwara H,Shoda K,Kosuga T,Kubota T,Okamoto K,Arita T,Morimura R,Murayama Y,Ikoma H,Kuriu Y,Nakanishi M,Otsuji E

更新日期：2018-12-01 00:00:00

abstract：BACKGROUND/AIM:The hormonally-active form of vitamin D, 1,25(OH)2D3, demonstrated activity against oral squamous cell carcinoma (OSCC). Cytochrome P450scc (CYP11A1)-derived vitamin D hydroxyderivatives, such as 20(OH)D3 and 1,20(OH)2D3, have overlapping beneficial effects with 1,25(OH)2D3 without causing hypercalcemia....

journal_title：Anticancer research

authors： Oak ASW,Bocheva G,Kim TK,Brożyna AA,Janjetovic Z,Athar M,Tuckey RC,Slominski AT

更新日期：2020-05-01 00:00:00

abstract：BACKGROUND/AIM:N6-Methyladenosine (m6A), the most abundant internal modification of RNA, plays a critical role in cancer development. However, the clinical implications of m6A in hepatocellular carcinoma (HCC) remain unclear. MATERIALS AND METHODS:We analyzed 177 HCC and paired noncancerous liver tissues from patients...

journal_title：Anticancer research

authors： Nakagawa N,Tanaka K,Sonohara F,Kandimalla R,Sunagawa Y,Inokawa Y,Takami H,Hayashi M,Yamada S,Kanda M,Tanaka C,Nakayama G,Koike M,Kodera Y

更新日期：2020-12-01 00:00:00

abstract：:Throughout the world, breast cancer is among the major causes of cancer-related death and is the most common cancer found in women. The development of cancer molecular knowledge has surpassed the novel concept of cancer biology and unraveled principle targets for anticancer drug developments and treatment strategies. ...

journal_title：Anticancer research

authors： Tungsukruthai S,Petpiroon N,Chanvorachote P

更新日期：2018-05-01 00:00:00

abstract：BACKGROUND/AIM:Chemotherapy-associated toxicity is one of the limiting factors regarding treatment efficacy, patient outcome and quality of life in this collective. Underweight or obese patients represent a major group in which the therapy seems to be more challenging. The aim of this analysis was to evaluate the impac...

journal_title：Anticancer research

authors： Grabowski JP,Richter R,Rittmeister H,Chekerov R,Woopen H,Sehouli J

更新日期：2018-10-01 00:00:00

abstract：:Three monoclonal antiidiotypic antibodies (AIA) to MOPC 315 IgA, G3 (IgG2b), A2 (IgG1) and D10 (a hybrid molecule consisting of gamma 1 and gamma 2a heavy chains), were characterized with respect to their binding constants (Ka) to MOPC 315 mouse myeloma cells. The Ka of G3 and A2 was 10(8)/mole; and that of D10 was 3 ...

journal_title：Anticancer research

authors： Marks A,Baumal R,Lei M,Ahmad A,Liu E

更新日期：1985-07-01 00:00:00

abstract：BACKGROUND/AIM:Vimentin3 (Vim3) was recently described as a tumour marker for the direct discrimination between benign and malignant kidney tumours. Here, we examined its expression in prostate cancer (PCa) cell lines and the regulation of its expression by endothelin receptors. MATERIALS AND METHODS:Prostate cancer c...

journal_title：Anticancer research

authors： KÖditz B,Stog A,GÖbel H,Heidegger I,Fries J,Heidenreich A,VON Brandenstein M

更新日期：2021-01-01 00:00:00

abstract：:Thirty human renal cell carcinomas and 94 non-small cell lung carcinomas of previously untreated patients were analyzed for the presence of P-glycoprotein, glutathione S-transferase-pi and topoisomerase II by means of immunohistochemistry. In the renal cell carcinomas investigated, two resistance markers were seen in ...

journal_title：Anticancer research

authors： Volm M,Mattern J,Efferth T,Pommerenke EW

更新日期：1992-07-01 00:00:00

abstract：BACKGROUND:CD98 expression is high in various human neoplasms. However, the relationship of CD98 expression with the clinicopathological factors of gastric cancer (GC) remains unclear. This study examined CD98 expression and its clinicopathological impact on GC. PATIENTS AND METHODS:Three hundred and thirty-one patien...

journal_title：Anticancer research

authors： Satoh T,Kaira K,Takahashi K,Takahashi N,Kanai Y,Asao T,Horiguchi J,Oyama T

更新日期：2017-02-01 00:00:00

abstract：:Gross cystic disease (GCD) represents an advanced form of fibrocystic disease of the breast. Bearers of macrocysts have been reported to be at risk of developing breast cancer. Natural killer (NK) cells are a lymphocyte subset deeply involved in immunosurveillance against neoplasia. We investigated whether breast cyst...

journal_title：Anticancer research

authors： Ardizzoja M,Masera RG,Tacconis P,Sartori ML,Arisio R,Massobrio M,Angeli A

更新日期：1994-03-01 00:00:00

abstract：:The expression of the HMG-CoA-reductase and LDL-receptor genes was examined in primary human embryonic tumours and in normal human first trimester foetal tissues. All embryonic and extra-embryonic tissues examined contained RNA that hybridized with the HMG-CoA-reductase and LDL-receptor cDNA-probes. However, the trans...

journal_title：Anticancer research

authors： Engström W,Schofield PN

更新日期：1987-05-01 00:00:00

abstract：BACKGROUND:The process of tumour invasion and subsequent metastasis represents the most lethal aspect of cancer and is responsible for the majority of deaths among cancer patients. Our objective was to identify invasion-specific genes in a series of isogenic breast cancer cell lines of differing invasive potential usin...

journal_title：Anticancer research

authors： Hughes L,O'Brien SL,Gallagher WM,Mcdonnell S

更新日期：2007-05-01 00:00:00

abstract：BACKGROUND/AIM:Basaloid squamous cell carcinoma of the oesophagus (BSCCE) is a variant of oesophageal squamous cell carcinoma (ESCC), that has a more aggressive biological behaviour than that of typical ESCC. miR-3687 has been previously identified to be highly expressed in BSCCE. This study aimed to evaluate the progn...

journal_title：Anticancer research

authors： Hagio K,Furuya S,Nakamura J,Maruyama S,Shiraishi K,Shimizu H,Akaike H,Hosomura N,Kawaguchi Y,Amemiya H,Kawaida H,Sudo M,Inoue S,Kono H,Ichikawa D

更新日期：2019-02-01 00:00:00

abstract：BACKGROUND/AIM:Occult cancers' reported rates vary from 2-12% and serous tubal intraepithelial carcinomas (STICs) have been identified in 3-12% of the prophylactically removed tubes of women carrying a BRCA mutation. The aim of this study was to evaluate the incidence of tubal minor epithelial atypia (STIL), STIC, and ...

journal_title：Anticancer research

authors： Ricciardi E,Tomao F,Aletti G,Bazzurini L,Bocciolone L,Boveri S,Landoni F,Lapresa MT,Maruccio M,Parma G,Peccatori F,Petrella MC,Zanagnolo V,Colombo N,Maggioni A

更新日期：2017-09-01 00:00:00

abstract：BACKGROUND:Chronic lymphocytic leukemia (CLL) is characterized by a clonal accumulation of neoplastic lymphocytes, indicating disruption of apoptosis. PATIENTS AND METHODS:Differential methylation hybridization analysis was performed to identify novel target genes silenced by CpG island methylation in patients with CL...

journal_title：Anticancer research

authors： Schmidt-Wolf IG,Plass C,Byrd JC,Frevel K,Pietsch T,Waha A

更新日期：2016-09-01 00:00:00

abstract：BACKGROUND/AIM:Oral cancer represents approximately 2.5% of all cancers in the United States, with five- and 10-year survival rates of 62% and 51%. In the present study, lyophilized strawberries (LS) were evaluated for their potential to inhibit tumorigenesis in the hamster cheek pouch (HCP) model of oral cancer and fo...

journal_title：Anticancer research

authors： Casto BC,Knobloch TJ,Galioto RL,Yu Z,Accurso BT,Warner BM

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND:Since the anti-HER2 monoclonal antibody trastuzumab made its triumphant advance into breast cancer therapy, new selective agents, including pan-HER inhibitors are entering clinical practice. MATERIALS AND METHODS:This study investigates the expression of the four HER-family members, HER1-4, in 48 primary br...

journal_title：Anticancer research

authors： Fuchs IB,Siemer I,Bühler H,Schmider A,Henrich W,Lichtenegger W,Schaller G,Kuemmel S

更新日期：2006-11-01 00:00:00

abstract：:Caspase-3 is a key executioner cysteine protease involved in programmed cell death or apoptosis. A ribozyme to human caspase-3 was designed, tested by in vitro cleavage, and transfected into a drug-resistant variant (DLKP-A5F) of a human lung carcinoma cell line (DLKP). By both stable and transient transfection, this ...

journal_title：Anticancer research

authors： Cronin D,Daly C,O'Doherty T,Heenan M,Scanlon KJ,Clynes M

更新日期：2004-03-01 00:00:00

abstract：BACKGROUND:The aim of the study was to document the delay in diagnosis of Hodgkin's disease (HD) and clarify the impact on clinical stage and survival in our region. MATERIAL AND METHODS:A retrospective study of the records of 50 patients treated for primary HD in northern-Norway in the time period 1985 - 1993 was per...

journal_title：Anticancer research

authors： Norum J

更新日期：1995-11-01 00:00:00

abstract：:Cytotropic heterogeneous molecular lipid (CHML), which is a new anticancer agent with US patent number 5,260,067, has recently been shown to suppress tumor cell growth in multiple tumor lines and induce apoptosis in vitro (1). These results indicate that CHML may be an effective antitumor agent. In the present study, ...

journal_title：Anticancer research

authors： Zhan Q,Zhao SC,Xu Z

更新日期：2001-07-01 00:00:00

abstract：METHODS:Induction chemotherapy, consisting of 3 courses of cisplatin (30 mg/m2/i.v. 1st and 2nd day), epirubicin (30 mg/m2/i.v. 1st and 2nd day), etoposide (75 mg/m2/i.v. 1st and 2nd day) and bleomycin (15 mg/i.v. 1st and 2nd day), prior to radical hysterectomy and lymph nodes resection, was used in the primary treatme...

journal_title：Anticancer research

authors： Panetta A,Angelelli B,Martoni A

更新日期：1999-01-01 00:00:00

abstract：:Schwannomas are benign tumors that arise from neural sheath Schwann cells. Solitary benign schwannomas are generally located in the head and neck, often along the cranial nerves, and are a particularly rare neoplasm among tumors of the retroperitoneal space. A 67-year-old man undergoing a general health check was inci...

journal_title：Anticancer research

authors： Yoshino T,Yoneda K

更新日期：2008-09-01 00:00:00

abstract：BACKGROUND/AIM:Ras-related associated with diabetes (RRAD), a member of the Ras-related GTPase superfamily, is frequently methylated in several human cancers, though its methylation profile remains unclear in esophageal cancer. MATERIALS AND METHODS:We examined RRAD promoter hypermethylation using real-time quantitati...

journal_title：Anticancer research

authors： Jin Z,Feng X,Jian Q,Cheng Y,Gao Y,Zhang X,Wang L,Zhang Y,Huang W,Fan X,Chen S,Yu H,Zhao Z,Dong M,Liu J,Mori Y,Meltzer SJ

更新日期：2013-11-01 00:00:00

abstract：:Integrin alpha v-beta 3 is involved in tumor angiogenesis while the clinical significance of beta 3 integrin expression in colorectal cancer and lung metastases. Analysis was performed on 51 colorectal cancer patients (22 with subsequent lung metastasis and 29 without lung metastasis). Fifty-one primary tumors and 22 ...

journal_title：Anticancer research

authors： Sato T,Konishi K,Kimura H,Maeda K,Yabushita K,Tsuji M,Miwa A

更新日期：2001-01-01 00:00:00

abstract：:Thirty advanced breast cancer patients received Vinorelbine (VNB) according to two different schedules: a weekly i.v. bolus of 30 mg/m (14 patients) or a continuous infusion (CI) schedule comprising 8 mg i.v. bolus on day 1 followed by 8 mg/m2/die CI day 1 to 4, q 21 days (16 patients). 36% of patients had received at...

journal_title：Anticancer research

authors： Gasco M,Gardin G,Repetto L,Campora E,Rosso R

更新日期：1997-03-01 00:00:00

abstract：:In the present study, we report that ginsenoside-Rg5 (G-Rg5), a newly discovered diol-containing ginsenoside, blocks the cell cycle of human hepatoma SK-HEP-1 cells via the down-regulation of cyclin E-dependent kinase activity. The results from flow cytometric analyses show that G-Rg5 arrests the cell cycle of SK-HEP-...

journal_title：Anticancer research

authors： Lee KY,Lee YH,Kim SI,Park JH,Lee SK

更新日期：1997-03-01 00:00:00

abstract：:The effect of various physiological fluids on the radical intensity of sodium ascorbate and sodium 5,6-benzylidene-L-ascorbate (SBA) was investigated using ESR spectroscopy. Blood from various animals did not significantly affect the radical intensity of both ascorbates, whereas the corresponding plasma fractions sign...

journal_title：Anticancer research

authors： Satoh K,Ida Y,Asano K,Hisamitsu T,Inagaki M,Sho S,Kochi M,Tanaka T,Sakagami H

更新日期：1997-11-01 00:00:00

abstract：BACKGROUND/AIM:4H-1-Benzopyran-4-ones (chromones) provide a backbone structure for the chemical synthesis of potent anticancer drugs. In contrast to 2-(N-cyclicamino)chromones, the biological activity of 3-(N-cyclicamino)chromones has not been reported. In this study, cytotoxicity of 15 3-(N-cyclicamino)chromone deriva...

journal_title：Anticancer research

authors： Shi H,Nagai J,Sakatsume T,Bandow K,Okudaira N,Uesawa Y,Sakagami H,Tomomura M,Tomomura A,Takao K,Sugita Y

更新日期：2018-08-01 00:00:00

abstract：:Over 80% of clinically manifested prostate cancers respond to androgen withdrawal. Several alternatives to castration have been explored. Since a growth promoting role for androstenedione has been suggested, we investigated the effect of inhibition of 3 beta-hydroxy-steroid-dehydrogenase (3 beta-HSD), a key enzyme inv...

journal_title：Anticancer research

authors： Geldof AA,Dijkstra I,Newling DW,Rao BR

更新日期：1995-07-01 00:00:00