Reverse transcriptase in bacteria.

abstract：:Protection against maternal malaria has been associated with the acquisition of a specific antibody response that prevents adhesion of Plasmodium falciparum-infected erythrocytes to the glycosaminoglycan chondroitin-4-sulphate (CSA), which is present in the placental intervillous space. These antibodies are directed a...

journal_title：Molecular microbiology

authors： Andrews KT,Pirrit LA,Przyborski JM,Sanchez CP,Sterkers Y,Ricken S,Wickert H,Lépolard C,Avril M,Scherf A,Gysin J,Lanzer M

更新日期：2003-08-01 00:00:00

abstract：:The Escherichia coli rodA and ftsW genes and the spoVE gene of Bacillus subtilis encode membrane proteins that control peptidoglycan synthesis during cellular elongation, division and sporulation respectively. While rodA and ftsW are essential genes in E. coli, the B. subtilis spoVE gene is dispensable for growth and ...

journal_title：Molecular microbiology

authors： Henriques AO,Glaser P,Piggot PJ,Moran CP Jr

更新日期：1998-04-01 00:00:00

abstract：:The septum-located DNA translocase, FtsK, acts to co-ordinate the late steps of Escherichia coli chromosome segregation with cell division. The FtsK gamma regulatory subdomain interacts with 8 bp KOPS DNA sequences, which are oriented from the replication origin to the terminus region (ter) in each arm of the chromoso...

journal_title：Molecular microbiology

authors： Sivanathan V,Emerson JE,Pages C,Cornet F,Sherratt DJ,Arciszewska LK

更新日期：2009-02-01 00:00:00

abstract：:OmpR activates expression of the two-component regulatory system located on Salmonella pathogenicity island 2 (SPI-2) that controls the expression of a type III secretion system, as well as many other genes required for systemic infection in mice. Measurements of SsrA and SsrB protein levels under different growth con...

journal_title：Molecular microbiology

authors： Feng X,Walthers D,Oropeza R,Kenney LJ

更新日期：2004-11-01 00:00:00

abstract：:The Pseudomonas aeruginosa protein PtxS negatively regulates its own synthesis by binding to the upstream region of its gene. We have recently identified a 14 bp palindromic sequence within the ptxS upstream region as the PtxS operator site (OP1). In this study, we searched the P. aeruginosa genomic sequence to determ...

journal_title：Molecular microbiology

authors： Swanson BL,Hager P,Phibbs P Jr,Ochsner U,Vasil ML,Hamood AN

更新日期：2000-08-01 00:00:00

abstract：:Chlamydiae are obligate intracellular bacteria which undergo a unique developmental cycle, alternating between non-replicative elementary bodies (EBs) and replicative reticulate bodies (RBs). The transition from RB to EB is characterized by condensation of the chromosome into a dense nucleoid structure. The chlamydial...

journal_title：Molecular microbiology

authors： Barry CE 3rd,Brickman TJ,Hackstadt T

更新日期：1993-07-01 00:00:00

abstract：:Post-translational modifications account for much of the biological diversity generated at the proteome level. Of these, glycosylation is the most prevalent. Long thought to be unique to Eukarya, it is now clear that both Bacteria and Archaea are also capable of N-glycosylation, namely the covalent linkage of oligosac...

journal_title：Molecular microbiology

authors： Yurist-Doutsch S,Chaban B,VanDyke DJ,Jarrell KF,Eichler J

更新日期：2008-06-01 00:00:00

abstract：:The nucleotide sequence of the ugp genes of Escherichia coli K-12, which encode a phosphate-limitation inducible uptake system for sn-glycerol-3-phosphate and glycerophosphoryl diesters, was determined. The genetic organization of the operon differed from previously published results. A single promoter, containing a p...

journal_title：Molecular microbiology

authors： Overduin P,Boos W,Tommassen J

更新日期：1988-11-01 00:00:00

abstract：:Escherichia coli has two heat shock regulons under the transcriptional control of Esigma32 and EsigmaE RNA polymerases. These polymerases control the expression of genes, the products of which are needed for correct folding of proteins in the cytoplasm and the extracytoplasm respectively. In this study, we report that...

journal_title：Molecular microbiology

authors： Klein G,Dartigalongue C,Raina S

更新日期：2003-04-01 00:00:00

abstract：:The cell surface of Bacillus stearothermophilus PV72 is covered by a regular surface layer (S-layer) composed of single species of protein, SbsA, with a molecular weight of 130,000. Recently, the sequence of the corresponding gene (sbsA) has been determined. The SbsA coding region including the signal sequence was clo...

journal_title：Molecular microbiology

authors： Kuen B,Sára M,Lubitz W

更新日期：1996-02-01 00:00:00

abstract：:ClpP is the proteolytic subunit of the ATP-dependent Clp protease in eubacteria, mammals and plant chloroplasts. Cyanobacterial ClpP protein is encoded by a multigene family, producing up to four distinct isozymes. We have examined the importance of the first ClpP protein (ClpP1) isolated from the cyanobacterium Synec...

journal_title：Molecular microbiology

authors： Porankiewicz J,Schelin J,Clarke AK

更新日期：1998-07-01 00:00:00

abstract：:The Staphylococcus epidermidis genes icaABC are involved in the synthesis of the polysaccharide intercellular adhesin (PIA), which is located mainly on the cell surface, as shown by immunofluorescence studies with PIA-specific antiserum. PIA was shown to be a linear beta-1,6-linked glucosaminoglycan composed of at lea...

journal_title：Molecular microbiology

authors： Heilmann C,Schweitzer O,Gerke C,Vanittanakom N,Mack D,Götz F

更新日期：1996-06-01 00:00:00

abstract：:The gltX gene, encoding the glutamyl-tRNA synthetase (GluRS), and the valU operon, whose transcripts contain three tRNAVal/UAC and one tRNALys/UUU, are adjacent and divergently transcribed. It is the only known case of adjacent genes encoding an aminoacyl-tRNA synthetase and a tRNA precursor in Escherichia coli. The g...

journal_title：Molecular microbiology

authors： Champagne N,Lapointe J

更新日期：1998-03-01 00:00:00

abstract：:In contrast to most primary metabolism genes, the genes involved in secondary metabolism and certain nutrient utilization pathways are clustered in fungi. Recently a nuclear protein, LaeA, was found to be required for the transcription of several secondary metabolite gene clusters in Aspergillus nidulans. Here we show...

journal_title：Molecular microbiology

authors： Bok JW,Noordermeer D,Kale SP,Keller NP

更新日期：2006-09-01 00:00:00

abstract：:Listeria monocytogenes is a facultative intracellular pathogen which secretes a pore-forming cytolysin, listeriolysin O (LLO), necessary for intracellular growth. Clostridium perfringens is an extracellular pathogen which secretes a related cytolysin, perfringolysin O (PFO). When PFO is secreted by intracellular L. mo...

journal_title：Molecular microbiology

authors： Jones S,Preiter K,Portnoy DA

更新日期：1996-09-01 00:00:00

abstract：:The lipopolysaccharide (LPS) of H. influenzae is highly variable. Much of the structural diversity is derived from phase variation, or high frequency on-off switching, of molecules attached during LPS biosynthesis. In this study, we examined the dynamics of LPS phase variation following exposure to human serum as a so...

journal_title：Molecular microbiology

authors： Clark SE,Eichelberger KR,Weiser JN

更新日期：2013-05-01 00:00:00

abstract：:N-linked protein glycosylation occurs in all three branches of life, eukaryotes, bacteria and archaea. The simplest system is that of the bacterium, Campylobacter jejuni, in which a heptasaccharide glycan is added to multiple proteins from a single lipid carrier molecule. In the eukaryotic system a conserved tetradeca...

journal_title：Molecular microbiology

authors： Guerry P

更新日期：2011-09-01 00:00:00

abstract：:The presence of very different sets of enzymes, and in particular the presence of RNase E and RNase J, has been used to explain significant differences in RNA metabolism between the two model organisms Escherichia coli and Bacillus subtilis. However, these studies might have somewhat polarized our view of RNA metaboli...

journal_title：Molecular microbiology

authors： Taverniti V,Forti F,Ghisotti D,Putzer H

更新日期：2011-12-01 00:00:00

abstract：:Haemophilus influenzae is a human-specific pathogen and a major source of morbidity worldwide. Infection with this organism begins with colonization of the nasopharynx, a process that probably depends on adherence to respiratory epithelium. The Hia autotransporter protein is the major adhesin ex-pressed by a subset of...

journal_title：Molecular microbiology

authors： Laarmann S,Cutter D,Juehne T,Barenkamp SJ,St Geme JW

更新日期：2002-11-01 00:00:00

abstract：:Many filamentous cyanobacteria are capable of gliding motility by an undefined mechanism. Within the heterocyst-forming clades, some strains, such as the Nostoc spp. and Fisherella spp., are motile only as specialized filaments termed hormogonia. Here we report on the phenotype of inactivation of a methyl-accepting ch...

journal_title：Molecular microbiology

authors： Risser DD,Meeks JC

更新日期：2013-02-01 00:00:00

abstract：:To investigate the determining factors in the selection of the transcription start points (tsp) by RNA polymerase of Escherichia coli, we systematically deleted or substituted single base pairs (bps) at 25 putative critical positions in the two extended -10 promoters, P1 and P2, of the gal operon. These changes extend...

journal_title：Molecular microbiology

authors： Lewis DE,Adhya S

更新日期：2004-11-01 00:00:00

abstract：:Shigella flexneri kills macrophages through apoptosis, involving the induction of host cell DNA fragmentation and characteristic morphological changes. Shigella can only cause damage if it escapes from the phagolysosome into the cytoplasm. The S. flexneri cytotoxic genes have been localized to the ipa operon of shigel...

journal_title：Molecular microbiology

authors： Zychlinsky A,Kenny B,Ménard R,Prévost MC,Holland IB,Sansonetti PJ

更新日期：1994-02-01 00:00:00

abstract：:Cell differentiation is widespread during the development of multicellular organisms, but rarely observed in prokaryotes. One example of prokaryotic differentiation is the gram-negative bacterium Myxococcus xanthus. In response to starvation, this gliding bacterium initiates a complex developmental programme that resu...

journal_title：Molecular microbiology

authors： Hoiczyk E,Ring MW,McHugh CA,Schwär G,Bode E,Krug D,Altmeyer MO,Lu JZ,Bode HB

更新日期：2009-10-01 00:00:00

abstract：:The Escherichia coli rpsD12 allele, which reduces translational fidelity and elevates expression of heat shock protein (Hsp) genes, only enhanced Hsp gene expression in the presence of oxygen. Similarly, the rpsL141 allele, which reduces mistranslation and Hsp gene expression, failed to affect the Hsp regulon in cells...

journal_title：Molecular microbiology

authors： Fredriksson A,Ballesteros M,Dukan S,Nyström T

更新日期：2006-01-01 00:00:00

abstract：:The stable RNA promoters of Escherichia coli are exquisitely sensitive to variations in the superhelical density of DNA. Previously, we have shown that binding of the DNA architectural protein FIS at the upstream activating sequences (UASs) of stable RNA promoters prevents the transcription complexes from inactivation...

journal_title：Molecular microbiology

authors： Rochman M,Blot N,Dyachenko M,Glaser G,Travers A,Muskhelishvili G

更新日期：2004-07-01 00:00:00

abstract：:Recently, we identified a novel disulfide oxidoreductase, SdbA, in the oral bacterium Streptococcus gordonii. Disulfide oxidoreductases form disulfide bonds in nascent proteins using a CXXC catalytic motif. Typically, the N-terminal cysteine interacts with substrates, whereas the C-terminal cysteine is buried and only...

journal_title：Molecular microbiology

authors： Davey L,Cohen A,LeBlanc J,Halperin SA,Lee SF

更新日期：2016-01-01 00:00:00

abstract：:CTXphi is a filamentous phage that encodes cholera toxin, one of the principal virulence factors of Vibrio cholerae. CTXphi is unusual among filamentous phages because it can either replicate as a plasmid or integrate into the V. cholerae chromosome at a specific site. The CTXphi genome has two regions, the 'core' and...

journal_title：Molecular microbiology

authors： Waldor MK,Rubin EJ,Pearson GD,Kimsey H,Mekalanos JJ

更新日期：1997-06-01 00:00:00

abstract：:Engulfment of the forespore by the mother cell is a universal feature of endosporulation. In Bacillus subtilis, the forespore protein SpoIIQ and the mother cell protein SpoIIIAH form a channel, essential for endosporulation, through which the developing spore is nurtured. The two proteins also form a backup system for...

journal_title：Molecular microbiology

authors： Serrano M,Crawshaw AD,Dembek M,Monteiro JM,Pereira FC,Pinho MG,Fairweather NF,Salgado PS,Henriques AO

更新日期：2016-04-01 00:00:00

abstract：:We have analysed the capacity of the 11 phase-variable, opacity-associated (Opa) proteins encoded by Neisseria gonorrhoeae MS11 to mediate traversal across polarized monolayers of the human colonic carcinoma T84 cell line. Gonococci expressing either the heparan sulphate proteoglycan (HSPG) binding Opa protein (Opa50)...

journal_title：Molecular microbiology

authors： Wang J,Gray-Owen SD,Knorre A,Meyer TF,Dehio C

更新日期：1998-11-01 00:00:00

abstract：:We cloned the CaYFH1 gene that encodes the yeast frataxin homologue in Candida albicans. CaYFH1 was expressed in Deltayfh1 Saccharomyces cerevisiae cells, where it compensated for all the phenotypes tested except for the lack of cytochromes. Double DeltaCayfh1/DeltaCayfh1 mutant had severe defective growth, accumulate...

journal_title：Molecular microbiology

authors： Santos R,Buisson N,Knight SA,Dancis A,Camadro JM,Lesuisse E

更新日期：2004-10-01 00:00:00