Abstract:
:We simulate a simple phenomenological model describing phase behavior in a multicomponent membrane, a model capable of producing macroscopic phase separation, modulated phases, and microemulsions, all of which have been discussed in terms of raft phenomena. We show that one effect of thermal fluctuations on the mean-field phase diagram is that it permits a direct transition between either one of the coexisting liquid phases to a microemulsion. This implies that one system exhibiting phase separation can be related to a similar system exhibiting the heterogeneities characteristic of a microemulsion. The two systems could differ in their average membrane composition or in the relative compositions of their exoplasmic and cytoplasmic leaves. The model provides a unified description of these raft-associated phenomena.
journal_name
Biophys Jjournal_title
Biophysical journalauthors
Shlomovitz R,Maibaum L,Schick Mdoi
10.1016/j.bpj.2014.03.017subject
Has Abstractpub_date
2014-05-06 00:00:00pages
1979-85issue
9eissn
0006-3495issn
1542-0086pii
S0006-3495(14)00293-8journal_volume
106pub_type
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