Abstract：
OBJECTIVE:The aim of this study was to draw a picture of diagnostic assessment and patterns of care for rectal cancer in France using population-based registries data. METHODS:The study included a random sample of 669 cases of rectal cancers diagnosed in 2005. RESULTS:Diagnostic assessment was performed by colonoscopy in 91.4% of the cases. An abdominal computed tomography was performed in 59.4% of the cases and chest computed tomography in 47.8%. An R0 resection was performed in 65.8% of cases and an R1/R2 resection in 16.1%. A rectal endosocography was performed in 40.4% and MRI in 10.4%. The sphincter was preserved in 73.6% of patients aged younger than 75 years of age and in 62.5% of those older than 75 years of age (P=0.002). In cases of R0 resection, neoadjuvant radiotherapy was performed in 47.8% of patients younger than 75 years of age and in 34.1% of older patients (P=0.007). Postoperative chemotherapy was administered in 23.9% of stage II and 67.8% of stage III resected patients. CONCLUSION:The management of rectal cancers can be improved. Preoperative staging has not reached its full development; very few patients received neoadjuvant treatment, whereas adjuvant chemotherapy was often performed, although its benefit is still unclear. The management of elderly patients was less optimal than that of younger patients.
journal_name
Eur J Gastroenterol Hepatoljournal_title
European journal of gastroenterology & hepatologyauthors
Desgrippes R,Bouvier V,Delafosse P,Robaszkiewicz M,Molinié F,Trétarre B,Lepage C,Faivre J,Jooste V,Bouvier AMdoi
10.1097/MEG.0000000000000116subject
Has Abstractpub_date
2014-07-01 00:00:00pages
743-7issue
7eissn
0954-691Xissn
1473-5687journal_volume
26pub_type
杂志文章abstract：OBJECTIVE:To elucidate the role of Helicobacter pylori in relapsing disease after partial gastrectomy for peptic ulcer. DESIGN:Retrospective study of gastroscopies between January 1985 and February 1988. SETTING:Department of Surgery, Helsinki University Central Hospital, Finland. PARTICIPANTS:One hundred and fifty-...
journal_title：European journal of gastroenterology & hepatology
pub_type： 杂志文章
doi：
更新日期：1997-04-01 00:00:00
abstract：OBJECTIVES:The activation of hepatic stellate cells (HSC) is considered the most important event in hepatic fibrogenesis. The precise mechanism of this process is unknown in autoimmune hepatitis (AIH), and more evidence is needed on the evolution of fibrosis. The aim of this study was to assess these aspects in childre...
journal_title：European journal of gastroenterology & hepatology
pub_type： 杂志文章
doi：10.1097/MEG.0b013e328326cab6
更新日期：2010-03-01 00:00:00
abstract：BACKGROUND:Helicobacter pylori that is generally acquired in childhood and infects the gastric mucosa is considered to be responsible for many pathobiological changes that are linked to the pathogenesis of gastric cancer. Although the majority of studies on the subject have been carried out in adults, there are a limit...
journal_title：European journal of gastroenterology & hepatology
pub_type： 杂志文章
doi：10.1097/MEG.0000000000000246
更新日期：2015-02-01 00:00:00
abstract：OBJECTIVES:The distribution of the intestinal vascular lesions and their relation with the fibrinolysis process are poorly known in Crohn's disease (CD). The mediators of the plasminogen activator system, namely urokinase-type plasminogen activator (u-PA), tissue-type plasminogen activator (t-PA) and plasminogen activa...
journal_title：European journal of gastroenterology & hepatology
pub_type： 杂志文章
doi：10.1097/00042737-199910000-00007
更新日期：1999-10-01 00:00:00
abstract：BACKGROUND:Adalimumab (ADA) is a subcutaneous anti-tumour necrosis factor (anti-TNF) agent, effective in inducing and maintaining remission in Crohn's disease (CD). Unlike Infliximab (IFX), ADA dosing is not weight adjusted and dose frequency is based on clinical response. AIM:To determine whether obesity is a risk fa...
journal_title：European journal of gastroenterology & hepatology
pub_type： 杂志文章
doi：10.1097/MEG.0b013e32835d1f15
更新日期：2013-05-01 00:00:00
abstract：BACKGROUND:Synchronous colorectal carcinoma (CRC) is a specific and rare type of colorectal malignancy. The data on the impact of synchronous CRC are controversial. This study aimed to compare the characteristics and prognosis between synchronous CRC and solitary CRC. PATIENTS AND METHODS:252 patients who underwent su...
journal_title：European journal of gastroenterology & hepatology
pub_type： 杂志文章
doi：10.1097/MEG.0000000000001487
更新日期：2019-12-01 00:00:00
abstract：:Chronic hepatitis B continues to be a major global health burden. It accounts for a substantial impact on health care resources and finances in many parts of the world including Europe. Natural history and disease spectrum are varied, depending on when and how the infection is acquired. The chronic infective state inc...
journal_title：European journal of gastroenterology & hepatology
pub_type： 杂志文章,评审
doi：10.1097/MEG.0b013e3283474add
更新日期：2011-08-01 00:00:00
abstract：OBJECTIVE:Pregnant women often suffer from gastroesophageal reflux disease (GERD). GERD symptoms are known to influence the quality of life; however, there is a lack of data in pregnant women. The aim of this study was to establish the impact of GERD symptoms on health-related quality of life (HRQOL) during pregnancy. ...
journal_title：European journal of gastroenterology & hepatology
pub_type： 杂志文章
doi：10.1097/MEG.0000000000000905
更新日期：2017-08-01 00:00:00
abstract：:Prophylaxis with norfloxacin has been shown to be effective in preventing spontaneous bacterial peritonitis (SBP) in liver cirrhosis. This therapy is associated with the appearance of quinolone-resistant Escherichia coli. However, only four cases of SBP caused by quinolone-resistant E. coli have been reported so far. ...
journal_title：European journal of gastroenterology & hepatology
pub_type： 杂志文章
doi：10.1097/00042737-200201000-00014
更新日期：2002-01-01 00:00:00
abstract：OBJECTIVE:The threshold of gluten contamination in gluten-free products of both dietary and normal consumption is under debate. The objective of this study was to gather information on consumption of gluten-free products intended for dietary use of people under a gluten-free diet. This information is essential to ascer...
journal_title：European journal of gastroenterology & hepatology
pub_type： 杂志文章
doi：10.1097/01.meg.0000236884.21343.e4
更新日期：2006-11-01 00:00:00
abstract：OBJECTIVE:To modulate experimental colitis by the direct intramuscular injection of cDNA expression vector encoding transforming growth factor-beta 1. METHODS:Colitis was induced in rats by the intracolonic administration of 0.25 ml 50% ethanol containing 30 mg trinitrobenzene sulfonic acid. Three and 10 days later th...
journal_title：European journal of gastroenterology & hepatology
pub_type： 杂志文章
doi：
更新日期：1995-04-01 00:00:00
abstract：OBJECTIVE:To examine the relationship between Helicobacter pylori and recurrent ulceration after highly selective vagotomy (HSV). SETTING:Academic Department of Surgery at a teaching hospital. PATIENTS:Thirty-eight patients (26 men and 12 women) were studied 2-21 years after HSV. Seven patients had recurrent ulcerati...
journal_title：European journal of gastroenterology & hepatology
pub_type： 杂志文章
doi：
更新日期：1995-03-01 00:00:00
abstract：BACKGROUND AND AIMS:In many countries, current treatment for patients with chronic hepatitis C involves a combination of peginterferon and ribavirin, associated with a protease inhibitor for hepatitis C virus genotype 1. More recent and efficient less toxic antiviral treatments are now available for some patients. Thus...
journal_title：European journal of gastroenterology & hepatology
pub_type： 杂志文章,多中心研究
doi：10.1097/MEG.0000000000000506
更新日期：2016-02-01 00:00:00
abstract：BACKGROUND:Inflammatory bowel diseases (IBDs) are characterized by a breakdown of colon epithelial barrier function. Antimicrobial peptides like cathelicidins are molecules of the innate immune system located at epithelial surfaces. Cathelicidins influence microbial growth and inflammation and may play a role in IBD. I...
journal_title：European journal of gastroenterology & hepatology
pub_type： 杂志文章
doi：10.1097/00042737-200606000-00007
更新日期：2006-06-01 00:00:00
abstract：BACKGROUND AND AIM:Ascitic fluid infection (AFI) is a common complication in patients with cirrhosis and ascites. Mean platelet volume (MPV) and platelet distribution width (PDW) may be considered as simple and inexpensive indicators of inflammation in some diseases. We aimed to investigate whether platelet size altera...
journal_title：European journal of gastroenterology & hepatology
pub_type： 杂志文章
doi：10.1097/MEG.0000000000000202
更新日期：2014-12-01 00:00:00
abstract：OBJECTIVES:Data on heredity, risk factors and comorbidity in microscopic colitis, encompassing collagenous colitis (CC) and lymphocytic colitis (LC), are limited. AIM:The aim was to carry out a case-control study of family history, childhood circumstances, educational level, marital status, smoking and comorbidity in ...
journal_title：European journal of gastroenterology & hepatology
pub_type： 杂志文章
doi：10.1097/MEG.0000000000000832
更新日期：2017-05-01 00:00:00
abstract：BACKGROUND:Inflammatory bowel disease (IBD) is a debilitating immune disorder that impairs function and health-related quality of life (HRQOL). A goal of IBD treatment is mucosal healing, but it is not known whether it achieves normalization of the patients' perception of health. This can be assessed by using a cut-off...
journal_title：European journal of gastroenterology & hepatology
pub_type： 杂志文章,多中心研究
doi：10.1097/MEG.0b013e32835414b2
更新日期：2012-07-01 00:00:00
abstract：BACKGROUND:There are increasing indications for assessing Helicobacter pylori status by non-invasive means in dyspeptic patients. There is also increasing use of proton pump inhibitor therapy for dyspeptic disease. AIMS:To determine the effect of proton pump inhibitor therapy on the accuracy of the [14C]urea breath te...
journal_title：European journal of gastroenterology & hepatology
pub_type： 杂志文章
doi：10.1097/00042737-199809000-00006
更新日期：1998-09-01 00:00:00
abstract：OBJECTIVE:To investigate the variability in serum pepsinogen levels in an asymptomatic population. DESIGN:Cross-sectional survey of 420 men aged 18-63 years, without symptoms or a history of gastric disease, recruited from four factories in Stoke-on-Trent. METHODS:During an interview, data on history of gastric healt...
journal_title：European journal of gastroenterology & hepatology
pub_type： 杂志文章
doi：
更新日期：1995-07-01 00:00:00
abstract：BACKGROUND AND AIMS:The role of thyroid function in the portal hypertension development and prognosis remains unclear. This study aimed to investigate the correlation between serum-free triiodothyronine (fT3) levels and the outcomes of cirrhotic portal hypertension. METHODS:A total of 385 cirrhotic patients with confi...
journal_title：European journal of gastroenterology & hepatology
pub_type： 杂志文章
doi：10.1097/MEG.0000000000001658
更新日期：2020-10-01 00:00:00
abstract：OBJECTIVE:The quality of Barrett's surveillance relies on an adequate endoscopic inspection, obtaining a sufficient number of biopsy specimens, good communication of the endoscopic findings to the pathologist, and an accurate description of the histological findings by the pathologist. The aim of this study was to asse...
journal_title：European journal of gastroenterology & hepatology
pub_type： 杂志文章,多中心研究
doi：10.1097/MEG.0b013e3282f8295d
更新日期：2008-07-01 00:00:00
abstract：OBJECTIVE:To develop and validate a non-invasive index to predict the presence of cirrhosis in patients with chronic hepatitis C on the basis of clinical, laboratory, and ultrasound findings. MATERIALS AND METHODS:Data from the complete history and physical examination, serologic studies, liver ultrasound, and liver b...
journal_title：European journal of gastroenterology & hepatology
pub_type： 杂志文章
doi：10.1097/00042737-200601000-00010
更新日期：2006-01-01 00:00:00
abstract：OBJECTIVES:The primary aim of this study was to evaluate the histological adequacy of the liver tissue specimens obtained with a 20-gauge fine-needle biopsy needle and the secondary aim was to test the safety endoscopic ultrasound-guided liver biopsy with a 20-gauge fine-needle biopsy needle with the wet-heparinized su...
journal_title：European journal of gastroenterology & hepatology
pub_type： 杂志文章
doi：10.1097/MEG.0000000000001929
更新日期：2020-11-01 00:00:00
abstract：OBJECTIVE:We have previously identified that primary human hepatocellular carcinoma (HCC) is associated with altered guanine nucleotide regulatory protein (G-protein) expression concomitant with decreased adenylyl cyclase (AC) and increased mitogen activated protein kinase (MAPK) activity in vivo. This study aims to ad...
journal_title：European journal of gastroenterology & hepatology
pub_type： 杂志文章
doi：10.1097/00042737-199912000-00009
更新日期：1999-12-01 00:00:00
abstract：OBJECTIVE:To compare zaldaride maleate, a calmodulin inhibitor with gastrointestinal antisecretory properties, with loperamide and a placebo in the treatment of travellers' diarrhoea. DESIGN:Randomized, double-blind, double-dummy study. SETTING:Study clinic staffed by European residents on Nile cruise ships. PATIENT...
journal_title：European journal of gastroenterology & hepatology
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1995-09-01 00:00:00
abstract：OBJECTIVES:Patients with positive fecal occult blood test and unrevealing colonoscopy are often advised to undergo esophago-gastro-duodenoscopy (EGD) to exclude a bleeding source in the upper gastrointestinal tract. In this study, we evaluated EGD findings in patients with positive immunochemical fecal occult blood tes...
journal_title：European journal of gastroenterology & hepatology
pub_type： 杂志文章
doi：10.1097/MEG.0b013e32834059ff
更新日期：2010-12-01 00:00:00
abstract：:Coeliac disease is generally well controlled with gluten-free diet but a small proportion of patients require corticosteroids or immunomodulatory agents. Response to anti-tumour necrosis factor (anti-TNF) agents raises interesting questions about both the pathogenesis of coeliac disease and the mechanism of action of ...
journal_title：European journal of gastroenterology & hepatology
pub_type： 杂志文章,评审
doi：10.1097/00042737-200506000-00002
更新日期：2005-06-01 00:00:00
abstract：OBJECTIVE:This study was designed to evaluate the role of technetium-99m (99mTc) hexamethyl propylene amine oxime (HMPAO)-labelled leucocyte imaging as an initial screening test in patients suspected of having inflammatory bowel disease (IBD). PATIENTS AND METHODS:Thirty-one patients in whom a final diagnosis of irrit...
journal_title：European journal of gastroenterology & hepatology
pub_type： 杂志文章
doi：10.1097/00042737-199612000-00012
更新日期：1996-12-01 00:00:00
abstract：:Inflammatory bowel disease (IBD) is a chronic inflammatory process, the aetiology of which is complex and probably multi-factorial. Nutrition has been proposed to be an important aetiological factor for IBD. The present review critically examines the relationship between components of the diet (such as sugar, fat, fib...
journal_title：European journal of gastroenterology & hepatology
pub_type： 杂志文章,评审
doi：10.1097/00042737-200306000-00005
更新日期：2003-06-01 00:00:00
abstract：OBJECTIVE:For palliation of extrahepatic bile duct obstruction, self-expandable metal stents (SEMS) are superior to plastic stents in terms of stent patency and occurrence of stent dysfunction. We assessed health-related quality of life (HRQoL) after stent placement to investigate whether this also results in a differe...
journal_title：European journal of gastroenterology & hepatology
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1097/MEG.0000000000000762
更新日期：2017-02-01 00:00:00
