Consumption of gluten-free products: should the threshold value for trace amounts of gluten be at 20, 100 or 200 p.p.m.?

Abstract:

OBJECTIVE:The threshold of gluten contamination in gluten-free products of both dietary and normal consumption is under debate. The objective of this study was to gather information on consumption of gluten-free products intended for dietary use of people under a gluten-free diet. This information is essential to ascertain the exposure of coeliac patients to gluten through their diet and deduce the maximum gluten content that these products should contain to guarantee a safe diet. METHODS:A diet diary of consumption of gluten-free products intended for dietary use was distributed to the coeliac societies of two typical Mediterranean countries (Italy and Spain) and two Northern countries (Norway and Germany). The diet diary included a self-weigh table of the selected food items and a 10-day consumption table. Results were reported in percentiles as distributions were clearly right skewed. RESULTS:The respondents included in the study accounted for 1359 in Italy, 273 in Spain, 226 in Norway and 56 in Germany. Gluten-free products intended for dietary use contributed significantly to the diet of coeliac patients in Italy, Germany and Norway and to a lesser degree in Spain. The most consumed gluten-free product in all countries was bread, and it was double consumed in the Northern countries (P<0.001). Mediterranean countries showed consumption of a wider variety of gluten-free foods and pasta was eaten to a large degree in Italy. CONCLUSIONS:The differences between Northern and Mediterranean countries were not in the total amount of gluten-free products but in the type of products consumed. The observed daily consumption of gluten-free products results in the exposure to rather large amounts of gluten, thus the limit of 200 p.p.m. should be revised. A limit of 20 p.p.m. for products naturally gluten-free and of 100 p.p.m. for products rendered gluten-free is proposed to guarantee a safe diet and to enable coeliac patients to make an informed choice. These limits should be revised as new data become available.

authors

Gibert A,Espadaler M,Angel Canela M,Sánchez A,Vaqué C,Rafecas M

doi

10.1097/01.meg.0000236884.21343.e4

subject

Has Abstract

pub_date

2006-11-01 00:00:00

pages

1187-95

issue

11

eissn

0954-691X

issn

1473-5687

pii

00042737-200611000-00012

journal_volume

18

pub_type

杂志文章
  • Prognosis of patients with gastric variceal bleeding after endoscopic variceal obturation according to the type of varices.

    abstract:BACKGROUND AND AIMS:This study was performed to evaluate the treatment efficacy of endoscopic variceal obturation (EVO) in patients with gastric variceal bleeding (GVB) according to the type of varices. PATIENTS AND METHODS:All patients who were treated with EVO for bleeding from gastric varices (GVs) were included. P...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:10.1097/MEG.0000000000001271

    authors: Lee HA,Chang JM,Goh HG,Kim TH,Lee YS,Suh SJ,Jung YK,Choi HS,Kim ES,Kim JH,An H,Seo YS,Yim HJ,Jeen YT,Yeon JE,Chun HJ,Byun KS,Um SH,Kim CD,Korean Portal Hypertension Study Group.

    更新日期:2019-02-01 00:00:00

  • Should antibiotic treatment of Helicobacter-positive patients with non-ulcer dyspepsia now be recommended?

    abstract::Whether cure of Helicobacter pylori infection leads to sustained improvement of non-ulcer dyspepsia (NUD) symptoms is one of the most important unresolved clinical questions in this area. H. pylori has not helped in explaining pathophysiological abnormalities which may cause dyspepsia symptoms. Currently there is insu...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章,评审

    doi:10.1097/00042737-199805000-00002

    authors: Veldhuyzen van Zanten SJ,Talley NJ

    更新日期:1998-05-01 00:00:00

  • Dietary n-3 polyunsaturated fatty acids and the aetiology of ulcerative colitis: a UK prospective cohort study.

    abstract:OBJECTIVES:The aetiology of ulcerative colitis (UC) is largely unknown, although it is plausible that dietary n-3 polyunsaturated fatty acids (PUFAs) may be protective. Metabolites derived from n-3 PUFAs are less proinflammatory than those from n-6 PUFAs. Earlier, no prospective cohort studies have investigated this hy...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:10.1097/MEG.0b013e3283352d05

    authors: John S,Luben R,Shrestha SS,Welch A,Khaw KT,Hart AR

    更新日期:2010-05-01 00:00:00

  • Characteristics of vacuolating toxin produced by Helicobacter pylori.

    abstract:OBJECTIVE:We sought a good indicator cell line to use in detecting the vacuolating toxin produced by Helicobacter pylori and in examining the characteristics of the toxin. DESIGN AND METHODS:Using five cell lines [baby hamster kidney (BHK-21), human amnion (FL), human uterine cancer (HeLa), rabbit kidney (RK-13) and A...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:

    authors: Kamiya S,Kai M,Ozawa A,Kobayashi H,Shirai T,Harasawa S,Miwa T

    更新日期:1994-12-01 00:00:00

  • Safety of variceal band ligation in patients with cirrhosis and portal vein thrombosis treated with anticoagulant therapy: A retrospective study.

    abstract:BACKGROUND AND AIMS:Anticoagulant therapy has been recommended in patients with cirrhosis and portal vein thrombosis especially in candidates for liver transplantation. These patients are also likely to need variceal band ligation. This study aimed to assess the incidence of upper gastrointestinal bleeding after electi...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:10.1097/MEG.0000000000001522

    authors: Ponthus S,Spahr L,Casini A,Berney T,Frossard JL,Majno P,Elkrief L

    更新日期:2020-03-01 00:00:00

  • Haematochezia in Crohn's disease caused by late-onset haemobilia following percutaneous liver biopsy.

    abstract::The case of a patient with Crohn's disease and who presented 4 days after a percutaneous liver biopsy with haematochezia suggestive of an exacerbation of his inflammatory bowel disease is described. Subsequent abdominal ultrasonography revealed free fluid in the peritoneal cavity and around the gallbladder. Haemobilia...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:10.1097/00042737-200402000-00018

    authors: Hodgson RS,Taylor-Robinson SD,Jackson JE

    更新日期:2004-02-01 00:00:00

  • A new organotypic model to study cell interactions in the intestinal mucosa.

    abstract:BACKGROUND:Recently, we demonstrated that freshly elutriated monocytes differentiate into macrophages with a phenotype similar to that of intestinal macrophages in a three-dimensional model of intestinal epithelial cells. Here we describe a more organotypic model to study cell interactions in the intestinal mucosa. ME...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:10.1097/00042737-200608000-00017

    authors: Spottl T,Hausmann M,Gunckel M,Herfarth H,Herlyn M,Schoelmerich J,Rogler G

    更新日期:2006-08-01 00:00:00

  • Short article: Outcome of medical and surgical management for perforated jejunal diverticulitis.

    abstract:OBJECTIVES:Perforated jejunal diverticulitis (PJD) is rare, but it has high mortality rates. The role of nonsurgical management is debated. The aim of this study is to assess the outcomes of medical and surgical management of PJD. PATIENTS AND METHODS:A single-centre study on a series of emergency patients diagnosed w...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:10.1097/MEG.0000000000001265

    authors: Garcia-Granero A,Argüelles BG,Gallardo CM,Carreño O,Giner F,Pellino G,Frasson M

    更新日期:2019-01-01 00:00:00

  • Incontinence and anorectal dysfunction in patients with diabetes mellitus.

    abstract::The elucidation of the pathogenesis of faecal incontinence in patients with advanced diabetes mellitus has progressed during the last 15 years. In contrast to earlier concepts which promoted the concept that high stool volumes overwhelm normal continence mechanisms, recent studies indicate that the vast majority of di...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章,评审

    doi:

    authors: Wald A

    更新日期:1995-08-01 00:00:00

  • Limited usefulness of a seven-day twice-a-day quadruple therapy.

    abstract:OBJECTIVE:To test the usefulness of a twice-a-day, simplified quadruple therapy to cure Helicobacter pylori infection. DESIGN:Helicobacter pylori-positive ulcer patients were treated with omeprazole 20 mg twice a day (b.d.), amoxicillin 1 g b.d., tinidazole 500 mg b.d. and bismuth subcitrate 240 mg b.d. for 7 days in ...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 临床试验,杂志文章

    doi:10.1097/00042737-200012120-00008

    authors: Garcia N,Calvet X,Gené E,Campo R,Brullet E

    更新日期:2000-12-01 00:00:00

  • Abnormal brain processing in hepatic encephalopathy: evidence of cerebral reorganization?

    abstract:BACKGROUND AND AIM:Hepatic encephalopathy (HE) is a severe and frequent complication of liver cirrhosis characterized by abnormal cerebral function. Little is known about the underlying neural mechanisms in HE and human data are sparse. Electrophysiological methods such as evoked brain potentials after somatic stimuli ...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:10.1097/MEG.0b013e32833d4717

    authors: Blauenfeldt RA,Olesen SS,Hansen JB,Graversen C,Drewes AM

    更新日期:2010-11-01 00:00:00

  • Hyperbaric oxygen as a treatment for malabsorption in a radiation-damaged short bowel.

    abstract::Radiation enteritis can be challenging to diagnose and treat. We report the case of a 44-year-old woman who was diagnosed with a squamous cell carcinoma of the cervix in 1978 and treated with hysterectomy and post-operative radiotherapy. Over the next 20 years she required multiple intestinal operations resulting in s...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:10.1097/00042737-200606000-00017

    authors: Huddy JE,Patel P,Johnson MW,Hamilton-Farrell MR,Ede RJ,Sanderson JD

    更新日期:2006-06-01 00:00:00

  • Does the declining prevalence of Helicobacter pylori unmask patients with idiopathic peptic ulcer disease? Trends over an 8 year period.

    abstract:OBJECTIVES:Recent studies have suggested that the prevalence of Helicobacter pylori infection in patients with ulcer disease who were not using non-steroidal anti-inflammatory drugs (NSAIDs) has been overestimated. The decreasing prevalence of H. pylori could lead to a relative increase in the number of patients with t...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:10.1097/01.meg.0000108367.19243.73

    authors: Arents NL,Thijs JC,van Zwet AA,Kleibeuker JH

    更新日期:2004-08-01 00:00:00

  • Length of endoscopic workup in gastrointestinal bleeding.

    abstract:BACKGROUND:The number of procedures utilized in the general management of gastrointestinal bleeding (GIB) has not been investigated previously. We used the National Endoscopic Database of the Clinical Outcomes Research Initiative for an observational study to analyze the average length of workup in GIB. METHODS:The el...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:10.1097/MEG.0000000000000693

    authors: Woodward Z,Williams JL,Sonnenberg A

    更新日期:2016-10-01 00:00:00

  • Relationship between genotypes of hepatitis C virus and histopathological manifestations in chronic hepatitis C patients.

    abstract:OBJECTIVE:The aim of this study was to assess the relationship between HCV genotype and histological liver injury. DESIGN:Prospective study on a cohort of patients with biopsy proven chronic hepatitis C. SETTING:University medical centre. PARTICIPANTS:Enrolled were 324 consecutive patients (male 197, median age 52 y...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:10.1097/00042737-200012030-00007

    authors: Adinolfi LE,Utili R,Andreana A,Tripodi MF,Rosario P,Mormone G,Ragone E,Pasquale G,Ruggiero G

    更新日期:2000-03-01 00:00:00

  • Palliative chemotherapy in advanced gastrointestinal cancer.

    abstract::In this review, the role of chemotherapy in the palliative treatment of advanced gastrointestinal cancer is discussed. Emphasis is placed on chemotherapy-related problems, current chemo-therapy options, and new developments. ...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章,评审

    doi:10.1097/00042737-200012040-00004

    authors: van Riel JM,van Groeningen CJ

    更新日期:2000-04-01 00:00:00

  • Resolution of a complex mediastinal pseudocyst in a patient with alcohol-related chronic pancreatitis following abstinence from alcohol.

    abstract::We describe a 55-year-old patient with alcoholic chronic pancreatitis, a large mediastinal pseudocyst and a hemorrhagic pleural effusion. A single thoracocentesis and withdrawal of alcohol without other conservative or invasive measures resulted in a complete resolution of the pleural effusion and the mediastinal pseu...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:10.1097/00042737-200601000-00020

    authors: Groeneveld JH,Tjong A Lieng JG,de Meijer PH

    更新日期:2006-01-01 00:00:00

  • Comparison of tests for assessment of Helicobacter pylori eradication: results of a multi-centre study using centralized facility testing.

    abstract:BACKGROUND:The accuracy of diagnostic tests to assess Helicobacter pylori eradication has rarely been performed. AIM:To compare the tests most commonly used for this purpose, i.e. histology, culture and (13)C urea breath test performed in centralized facilities. METHODS:Prospective study where patients were included ...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章,多中心研究

    doi:10.1097/00042737-200012060-00009

    authors: Mégraud F,Burette A,Glupczynski Y,Fiocca R,Logan R,Quina M,Ericsson S,O'Morain C

    更新日期:2000-06-01 00:00:00

  • Clinical and surgical recurrence of Crohn's disease after ileocolonic resection in a specialist unit.

    abstract:BACKGROUND:Postoperative clinical and endoscopic recurrence is common in Crohn's disease. AIM:We aimed to assess postoperative recurrence and management in a cross-sectional patient cohort in one specialist unit, before the introduction of a uniform postoperative preventive strategy. METHODS:Review of patients who ha...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:10.1097/MEG.0b013e328326a01e

    authors: Ng SC,Lied GA,Arebi N,Phillips RK,Kamm MA

    更新日期:2009-05-01 00:00:00

  • Total bile acid levels are associated with left atrial volume and cardiac output in patients with cirrhosis.

    abstract:BACKGROUND AND AIMS:Bile acids (BAs) are potent signaling molecules involved in the regulation of several metabolic and functional aspects of cardiovascular homeostasis. BA pool alteration in cirrhosis may contribute toward the development of hemodynamic and cardiac disturbances. We aimed to investigate the association...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:10.1097/MEG.0000000000001043

    authors: Voiosu AM,Wiese S,Voiosu TA,Hove J,Bendtsen F,Møller S

    更新日期:2018-04-01 00:00:00

  • Cardiac dysfunction in patients with cirrhosis: is the systolic component its main feature?

    abstract:OBJECTIVE:To investigate the subclinical cardiac morphological and functional modifications in cirrhotic patients according to the stage of liver disease. PATIENTS AND METHODS:One hundred and thirteen cirrhotic patients underwent standard Doppler echocardiography and were compared with healthy individuals. Left ventri...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:10.1097/MEG.0000000000000340

    authors: Cesari M,Fasolato S,Rosi S,Angeli P

    更新日期:2015-06-01 00:00:00

  • Long-term rifaximin therapy as a primary prevention of hepatorenal syndrome.

    abstract:BACKGROUND:Hepatorenal syndrome (HRS) is a severe complication of liver cirrhosis, with poor survival. Rifaximin is a gut-selective broad-spectrum antibiotic. AIM:The aim of this study was to evaluate the role of rifaximin as a primary prevention of HRS. PATIENTS AND METHODS:Eighty patients with liver cirrhosis and a...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/MEG.0000000000000967

    authors: Ibrahim ES,Alsebaey A,Zaghla H,Moawad Abdelmageed S,Gameel K,Abdelsameea E

    更新日期:2017-11-01 00:00:00

  • Photodynamic therapy of human Barrett's cancer using 5-aminolaevulinic acid-induced protoporphyrin IX: an in-vivo dosimetry study in athymic nude mice.

    abstract:OBJECTIVE:There has been a dramatic increase in recent years in the incidence of Barrett's oesophagus and the oesophageal adenocarcinoma associated with it. Alongside surgical treatment for early Barrett's carcinomas, endoscopic treatment procedures such as photodynamic therapy (PDT), which have much lower complication...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:10.1097/00042737-200206000-00011

    authors: Pech O,Nagy CD,Gossner L,May A,Ell C

    更新日期:2002-06-01 00:00:00

  • Cost-effectiveness and long-term impact of Helicobacter pylori 'test and treat' service in reducing open access endoscopy referrals.

    abstract:INTRODUCTION:We have shown that the introduction of a carbon urea breath test (13C-UBT) service for Helicobacter pylori screening and eradication is effective in reducing the rate of open access endoscopy referrals in patients aged < 40 years in the short term. This has been substantiated by several randomized controll...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:10.1097/00042737-200410000-00005

    authors: Sreedharan A,Clough M,Hemingbrough E,Gatta L,Chalmers DM,Axon AT,Moayyedi P

    更新日期:2004-10-01 00:00:00

  • Immunosuppressive treatment for refractory ulcerative colitis--where do we stand and where are we going?

    abstract::Effective medical treatment of ulcerative colitis is available. However, 20-40% of patients remain refractory and become steroid dependent, or have chronic activity. Azathioprine and its metabolite 6-mercaptopurine have been found to be effective in this setting, although duration of treatment and doses are not entire...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章,评审

    doi:10.1097/00042737-199709000-00004

    authors: Schölmerich J

    更新日期:1997-09-01 00:00:00

  • Holes in gastric mucosa in upper gastrointestinal endoscopy.

    abstract::Gastritis cystica profunda (GCP) is a rare disease that shows multiple cystic gastric glands dispersed within the submucosa of the stomach. GCP occurs most commonly in patients who have undergone previous gastric surgery and presents as subepithelial tumor or a polypoid lesion. Here, we report the case of GCP in a 79-...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:10.1097/MEG.0000000000000050

    authors: Effenberger M,Steinle H,Offner FA,Vogel W,Millonig G

    更新日期:2014-06-01 00:00:00

  • Is nutrition an aetiological factor for inflammatory bowel disease?

    abstract::Inflammatory bowel disease (IBD) is a chronic inflammatory process, the aetiology of which is complex and probably multi-factorial. Nutrition has been proposed to be an important aetiological factor for IBD. The present review critically examines the relationship between components of the diet (such as sugar, fat, fib...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章,评审

    doi:10.1097/00042737-200306000-00005

    authors: Cashman KD,Shanahan F

    更新日期:2003-06-01 00:00:00

  • Change of clinical characteristics of ulcerative colitis in Japan: analysis of 844 hospital-based patients from 1981 to 2000.

    abstract:BACKGROUND:Although the number of ulcerative colitis patients has increased rapidly in Japan, few reports have been published regarding their clinical aspects. We investigated the clinical characteristics and chronological change of ulcerative colitis in Japanese patients. METHODS:Patients diagnosed with ulcerative co...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章,多中心研究

    doi:10.1097/MEG.0b013e3280110fb9

    authors: Fujimoto T,Kato J,Nasu J,Kuriyama M,Okada H,Yamamoto H,Mizuno M,Shiratori Y,Japan West Ulcerative Colitis (JWUC) Study Group.

    更新日期:2007-03-01 00:00:00

  • Labour productivity losses caused by premature death associated with hepatitis C in Spain.

    abstract:BACKGROUND AND AIMS:Hepatitis C virus (HCV) infection places a huge burden on healthcare systems. There is no study assessing the impact of HCV infection on premature deaths in Spain. The aim of this study was to estimate productivity losses because of premature deaths attributable to hepatitis C occurring in Spain dur...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:10.1097/MEG.0000000000000336

    authors: Oliva-Moreno J,Peña-Longobardo LM,Alonso S,Fernández-Bolaños A,Gutiérrez ML,Hidalgo-Vega Á,de la Fuente E,Fernández-Rodríguez CM

    更新日期:2015-06-01 00:00:00

  • Genetic susceptibility to primary biliary cirrhosis.

    abstract::Family studies suggest that genetic factors play a role in determining susceptibility to primary biliary cirrhosis (PBC). A number of polymorphic genes with small and additive effects may thus encode factors predisposing to this 'polygenic' disease. All the published data on genetic predisposition to PBC have been obt...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章,评审

    doi:10.1097/00042737-199906000-00004

    authors: Agarwal K,Jones DE,Bassendine MF

    更新日期:1999-06-01 00:00:00