The effects of mechanical immobilization on sutural development in the growing rabbit.

Abstract:

:Methyl-2-cyanoacrylate was used to mechanically immobilize the coronal suture unilaterally in a series of New Zealand white rabbits at varying ages. The animals were separated into groups; some were sacrificed at 30 day and some at 60 days postoperatively. Amalgam markers were placed in the parietal and frontal bones across the coronal suture, and were measured immediately after surgery and at the time of sacrifice to confirm mechanical immobility. The animals were studied radiographically and histologically in order to document the presence or absence of sutural bone union. Based on the results of this study, it appears that immobilization of the coronal suture results in the formation of an ectocranial periosteal bone bridge in rabbits less than 8 weeks of age. Bone union was not found in animals older than 8 weeks of age. This age-related difference in response is believed to be due to decreased periosteal depository activity on the ectocranial surface of the calvaria once the brain ceases to expand actively. Furthermore, bone union or synostosis was never seen within or across the internal portion of the sutural ligament. It is suggested, therefore, that sutural immobilization at young ages in the rabbit does not result in sutural synostosis and that the term "periosteal bone bridge" should be used when referring to this biological response.

journal_name

J Neurosurg

journal_title

Journal of neurosurgery

authors

Foley WJ,Kokich VG

doi

10.3171/jns.1980.53.6.0794

subject

Has Abstract

pub_date

1980-12-01 00:00:00

pages

794-801

issue

6

eissn

0022-3085

issn

1933-0693

journal_volume

53

pub_type

杂志文章
  • Gamma Knife radiosurgery in the treatment of abducens nerve schwannomas: a retrospective study.

    abstract::OBJECTIVE Of the intracranial schwannomas, those arising from the vestibular nerves are the most common. Abducens nerve (AN) schwannomas are very rare, and there is limited literature on their optimal management. Therapeutic options include surgery and/or stereotactic radiosurgery. The aim of this study was to evaluat...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/2015.8.JNS151140

    authors: Prasad GL,Sharma MS,Kale SS,Agrawal D,Singh M,Sharma BS

    更新日期:2016-10-01 00:00:00

  • Surgical management of the recurrence and regrowth of craniopharyngiomas.

    abstract:OBJECT:The authors performed a retrospective analysis of a consecutive series of craniopharyngiomas and their recurrences, which were managed with surgery alone. METHODS:In the past 20 years, 37 consecutive patients with craniopharyngiomas underwent surgery without adjuvant radiotherapy. During that period there was a...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.2005.103.2.0224

    authors: Minamida Y,Mikami T,Hashi K,Houkin K

    更新日期:2005-08-01 00:00:00

  • Deep brain stimulation for the early treatment of the minimally conscious state and vegetative state: experience in 14 patients.

    abstract::OBJECTIVE An effective treatment of patients in a minimally conscious state (MCS) or vegetative state (VS) caused by hypoxic encephalopathy or traumatic brain injury (TBI) is not yet available. Deep brain stimulation (DBS) of the thalamic reticular nuclei has been attempted as a therapeutic procedure mainly in patient...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/2016.10.JNS161071

    authors: Chudy D,Deletis V,Almahariq F,Marčinković P,Škrlin J,Paradžik V

    更新日期:2018-04-01 00:00:00

  • Cognitive impairment and adjustment in patients without neurological deficits after aneurysmal SAH and early operation.

    abstract::The mortality rate has recently been reduced to only a small percentage of patients selected for early aneurysm surgery. Despite recovery without neurological deficits, however, a diffuse encephalopathy may remain, with emotional and psychological sequelae that will interfere with rehabilitation and social reintegrati...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.1985.62.5.0673

    authors: Ljunggren B,Sonesson B,Säveland H,Brandt L

    更新日期:1985-05-01 00:00:00

  • Comparison of clipping and coiling in elderly patients with unruptured cerebral aneurysms.

    abstract::OBJECTIVE The comparative effectiveness of the 2 treatment options-surgical clipping and endovascular coiling-for unruptured cerebral aneurysms remains an issue of debate and has not been studied in clinical trials. The authors investigated the association between treatment method for unruptured cerebral aneurysms and...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/2016.1.JNS152028

    authors: Bekelis K,Gottlieb DJ,Su Y,O'Malley AJ,Labropoulos N,Goodney P,Lawton MT,MacKenzie TA

    更新日期:2017-03-01 00:00:00

  • Cerebral aneurysms in childhood and adolescence.

    abstract::In this study, 24 aneurysms occurring in 23 patients under the age of 18 years (mean 12 years) are analyzed. The male:female ratio was 2.8:1, and the youngest patient was 3 months old. Mycotic lesions and those associated with other vascular malformations were excluded. Forty-two percent of the aneurysms were located ...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章,评审

    doi:10.3171/jns.1989.70.3.0420

    authors: Meyer FB,Sundt TM Jr,Fode NC,Morgan MK,Forbes GS,Mellinger JF

    更新日期:1989-03-01 00:00:00

  • Use of a Peltier chip with a newly devised local brain-cooling system for neocortical seizures in the rat. Technical note.

    abstract::Local cortical cooling for termination of epileptic discharges (EDs) has recently become a focus of research. The authors report on a newly devised cooling system that uses a thermoelectric (Peltier) chip and examine the system's performance in experimental neocortical seizures. Experiments were performed in adult mal...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.2006.104.1.150

    authors: Imoto H,Fujii M,Uchiyama J,Fujisawa H,Nakano K,Kunitsugu I,Nomura S,Saito T,Suzuki M

    更新日期:2006-01-01 00:00:00

  • Long-term follow-up study of unruptured vertebral artery dissection: clinical outcomes and serial angiographic findings.

    abstract:OBJECT:Although the spontaneous occurrence of an unruptured vertebral artery (VA) dissection has increasingly been recognized as a relatively common cause of stroke, and the clinical aspects of this lesion have gradually been determined, its natural course remains obscure. The main goal of this study was to clarify the...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.2000.93.1.0019

    authors: Nakagawa K,Touho H,Morisako T,Osaka Y,Tatsuzawa K,Nakae H,Owada K,Matsuda K,Karasawa J

    更新日期:2000-07-01 00:00:00

  • Intraoperative evaluation of cerebral hemodynamics using directional Doppler technique. Part 2: Saccular aneurysms.

    abstract::The use of a pulsed echo Doppler technique during procedures for occlusion of intracranial aneurysms is described. Saccular aneurysms can be located with reference to probe position and depth setting. Tracings of intra-aneurysmal flow are presented, and the characteristic flow pattern is disucssed. Special emphasis ha...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.1979.50.5.0570

    authors: Nornes H,Grip A,Wikeby P

    更新日期:1979-05-01 00:00:00

  • Pigmented villonodular synovitis of the spine: a clinical, radiological, and morphological study of 12 cases.

    abstract::Cases of pigmented villonodular synovitis (PVNS) that affect the axial skeleton are rare and thus information regarding its natural history, treatment, and prognosis remains limited. To characterize this lesion more fully, the authors reviewed their experience with 12 cases of PVNS of the spine (one of which had been ...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章,评审

    doi:10.3171/jns.1996.84.4.0592

    authors: Giannini C,Scheithauer BW,Wenger DE,Unni KK

    更新日期:1996-04-01 00:00:00

  • Imaging studies of cerebral hyperperfusion after carotid endarterectomy. Case report.

    abstract::A case is reported of severe unilateral hemispheric edema and localized hemorrhage associated with seizures following endarterectomy of an ipsilateral high-grade carotid stenosis. Imaging studies including angiography, computerized tomography (CT), magnetic resonance imaging/angiography, and xenon-CT, suggested postop...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.1995.83.1.0133

    authors: Penn AA,Schomer DF,Steinberg GK

    更新日期:1995-07-01 00:00:00

  • Evaluation of surgical treatment for neuropathic pain from neuroma in patients with injured peripheral nerves.

    abstract::OBJECTIVE Chronic neuropathic pain after peripheral nerve injury is a major clinical problem. Its management is difficult, and therapeutic approaches vary and include oral medication, neurostimulation, and surgery. The aim of this study was to assess the adequacy of surgical nerve revision in a large series of patient...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/2017.1.JNS161778

    authors: Decrouy-Duruz V,Christen T,Raffoul W

    更新日期:2018-04-01 00:00:00

  • Pure arterial malformations.

    abstract::OBJECTIVE Over the last half century, there have been isolated case reports of purely arterial malformations. In this study, the authors report a consecutive series of patients with pure arterial malformations, emphasizing the clinical and radiological features of these lesions. METHODS Pure arterial malformations wer...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/2017.2.JNS1744

    authors: Brinjikji W,Cloft HJ,Flemming KD,Comelli S,Lanzino G

    更新日期:2018-07-01 00:00:00

  • The pineal gland: anatomy, physiology, and clinical significance.

    abstract::Since the discovery of melatonin approximately 25 years ago, there has been intense study regarding the details of the structure and function of the pineal gland. This work is reviewed, with particular emphasis on those aspects of importance to human physiology and disease. ...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章,评审

    doi:10.3171/jns.1985.63.3.0321

    authors: Erlich SS,Apuzzo ML

    更新日期:1985-09-01 00:00:00

  • Asymptomatic subdural chondrosarcoma. Case report.

    abstract::This report describes a large, asymptomatic, subdural skeletal-type condrosarcoma originating from the meninges. Distinction between the mesenchymal and skeletal types of intracranial chondrosarcoma is important since they have different prognoses. ...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.1978.48.5.0825

    authors: Alvira MM,McLaurin RL

    更新日期:1978-05-01 00:00:00

  • Depressed skull fracture overlying the superior sagittal sinus as a cause of benign intracranial hypertension. Case report.

    abstract::The use of surgical treatment for depressed skull fractures that are located over major venous sinuses is a matter of controversy. However, if clinical and radiological findings of sinus obliteration and related intracranial hypertension are present, surgical decompression is indicated. The authors present the case of...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.1998.88.3.0598

    authors: Uzan M,Ciplak N,Dashti SG,Bozkus H,Erdinçler P,Akman C

    更新日期:1998-03-01 00:00:00

  • Cadaveric fibula, locking plate, and allogeneic bone matrix for anterior cervical fusions after cervical discectomy for radiculopathy or myelopathy.

    abstract:OBJECT:The authors have previously reported that the results of using cadaveric fibula and locking plate (CF/LP) fusion following anterior cervical discectomy (ACD) for cervical spondylotic radiculopathy and myelopathy are superior to those obtained using autologous iliac crest (AIC) grafts in the short term. The long-...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/spi.2001.95.1.0043

    authors: Shapiro S,Connolly P,Donnaldson J,Abel T

    更新日期:2001-07-01 00:00:00

  • Coccidioidomycotic brain abscess. Case report.

    abstract::Coccidioidomycosis is an infection originating in the San Joaquim Valley of southern California, but now seen with increasing frequency throughout southern California and the southwestern United States. Central nervous system involvement is usually manifested as meningitis. The authors present the case of a young man ...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.1994.80.1.0140

    authors: Mendel E,Milefchik EN,Ahmadi J,Gruen P

    更新日期:1994-01-01 00:00:00

  • Analysis of proliferation markers and p53 expression in gliomas of astrocytic origin: relationships and prognostic value.

    abstract::Consecutive paraffin sections of 105 astrocytomas and 15 oligoastrocytomas were examined for expression of p53, MIB-1 (Ki-67), and proliferating cell nuclear antigen (PCNA). The tumors had been examined previously for genetic abnormalities and by flow cytometry. Regardless of the tumor's stage and grade and the patien...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.1997.86.1.0121

    authors: Cunningham JM,Kimmel DW,Scheithauer BW,O'Fallon JR,Novotny PJ,Jenkins RB

    更新日期:1997-01-01 00:00:00

  • Intracranial extension of inflammatory pseudotumor of the orbit. Case report.

    abstract::Orbital pseudotumors are inflammatory lesions of the orbit of unknown etiology, which initially mimic an orbital neoplasm. Involvement of the other orbit is uncommon, and extension into the paranasal sinus rare. Intracranial extension of pseudotumor of the orbit is previously unreported. This is a case report of a pat...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.1984.60.3.0625

    authors: Kaye AH,Hahn JF,Craciun A,Hanson M,Berlin AJ,Tubbs RR

    更新日期:1984-03-01 00:00:00

  • Phase II study of ifosfamide, carboplatin, and etoposide in patients with a first recurrence of glioblastoma multiforme.

    abstract:OBJECT:The prognosis of recurrent glioblastoma multiforme (GBM) remains unsatisfactory. The authors conducted a Phase II study of ifosfamide, carboplatin, and etoposide (ICE) for a first recurrence of GBM to determine whether it prolonged a patient's good-quality life. METHODS:This trial was an open-label, single-cent...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/2009.5.JNS081738

    authors: Aoki T,Mizutani T,Nojima K,Takagi T,Okumura R,Yuba Y,Ueba T,Takahashi JA,Miyatake S,Nozaki K,Taki W,Matsutani M

    更新日期:2010-01-01 00:00:00

  • Subarachnoid hemorrhage without evident cause on initial angiography studies: diagnostic yield of subsequent angiography and other neuroimaging tests.

    abstract:OBJECT:The aim of this study was to assess the diagnostic yield of imaging tests performed in patients in whom the cause of subarachnoid hemorrhage (SAH) had not been demonstrated on initial angiography. METHODS:By reviewing medical records of 806 patients with SAH who had been admitted during a 6.5-year period, the a...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.2003.98.6.1235

    authors: Topcuoglu MA,Ogilvy CS,Carter BS,Buonanno FS,Koroshetz WJ,Singhal AB

    更新日期:2003-06-01 00:00:00

  • Comparing the risks of frameless stereotactic biopsy in eloquent and noneloquent regions of the brain: a retrospective review of 284 cases.

    abstract:OBJECT:Frameless stereotactic biopsy has been shown in multiple studies to be a safe and effective tool for the diagnosis of brain lesions. However, no study has directly evaluated its safety in lesions located in eloquent regions in comparison with noneloquent locations. In this study, the authors determine whether an...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/2009.3.JNS081695

    authors: Air EL,Leach JL,Warnick RE,McPherson CM

    更新日期:2009-10-01 00:00:00

  • The occurrence of dural invasion in pituitary adenomas.

    abstract::This report describes 60 dural specimens from patients with pituitary adenomas treated by transsphenoidal microsurgery, and attempts to define more precisely the clinical and pathological correlation of microscopic dural invasion. Analysis of the adenomas was based on four characteristics; size, surgical invasiveness ...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.1986.64.3.0402

    authors: Selman WR,Laws ER Jr,Scheithauer BW,Carpenter SM

    更新日期:1986-03-01 00:00:00

  • Posterior plates in the management of cervical instability: long-term results in 44 patients.

    abstract::Although posterior plates are increasingly used to manage cervical spinal instability, long-term follow-up evaluation of patients with a critical analysis of efficacy and complications has not been reported. The authors have retrospectively analyzed the outcome in 44 consecutive patients (37 males and seven females, a...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.1994.81.3.0341

    authors: Fehlings MG,Cooper PR,Errico TJ

    更新日期:1994-09-01 00:00:00

  • Association of apolipoprotein E gene polymorphism with small-vessel lesions and stroke type in moyamoya disease: a preliminary study.

    abstract::OBJECT The present study was conducted to investigate whether microbleeds or microinfarcts are associated with apolipoprotein E (APOE) gene polymorphisms in patients with moyamoya disease (MMD), and if so, whetherAPOE gene polymorphisms are also associated with stroke type in patients with MMD. METHODS This cross-sect...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章,多中心研究

    doi:10.3171/2015.5.JNS142973

    authors: Jang DK,Huh PW,Lee KS

    更新日期:2016-06-01 00:00:00

  • Sex differences in outcome following sports-related concussion.

    abstract:OBJECT:Females comprise an increasing percentage of the athlete population across all age groups, and analysis of recent literature reveals that they sustain more concussions in collegiate sports. Results of human and animal studies indicate that females may have poorer outcomes after traumatic brain injury; however, n...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.2005.102.5.0856

    authors: Broshek DK,Kaushik T,Freeman JR,Erlanger D,Webbe F,Barth JT

    更新日期:2005-05-01 00:00:00

  • Bilateral trigeminal neuralgia.

    abstract::Bilateral trigeminal neuralgia occurred in 32 (11.9%) of 269 consecutive patients who were treated with radiofrequency electrocoagulation (RFE). This is a higher incidence than has been reported before and may be explained by the prospective nature of the present study, the long follow-up period, and the inclusion of ...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.1987.67.1.0044

    authors: Brisman R

    更新日期:1987-07-01 00:00:00

  • Changes in gamma-aminobutyric acid and somatostatin in epileptic cortex associated with low-grade gliomas.

    abstract::The role of specific neuronal populations in epileptic foci was studied by comparing epileptic and non-epileptic cortex removed from patients with low-grade gliomas. Epileptic and nearby (within 1 to 2 cm) non-epileptic temporal lobe neocortex was identified using electrocorticography. Cortical specimens taken from fo...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.1992.77.2.0209

    authors: Haglund MM,Berger MS,Kunkel DD,Franck JE,Ghatan S,Ojemann GA

    更新日期:1992-08-01 00:00:00

  • Comparison of spinal cord gray matter and white matter softness: measurement by pipette aspiration method.

    abstract:OBJECT:Although the gray matter of the spinal cord has been thought to be softer than the white matter, there is no evidence to support this belief. Because the spinal cord is extremely soft, it has been difficult to measure the mechanical properties of the gray and white matter. The modulis of elasticity of the gray a...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/spi.2001.95.2.0221

    authors: Ozawa H,Matsumoto T,Ohashi T,Sato M,Kokubun S

    更新日期:2001-10-01 00:00:00