Abstract：
:The effects of consumption of environmental contaminants contained in carp (Cyprinus carpio) from Saginaw Bay, Michigan on various hematological parameters and liver integrity of adult female mink (Mustela vision) were determined. Mink were fed diets that contained 0 (control), 10, 20, or 40% carp prior to and throughout the reproductive period (182 days). The diets contained 0.015, 0.72, 1.53, and 2.56 mg polychlorinated biphenyls (PCBs)/kg diet and 1.0, 19, 40, and 81 pg 2,3,7,8-tetrachlorodibenzo-p-dioxin equivalents (TEQs)/g diet, respectively. Mink fed the diets containing carp showed a general dose-dependent occurrence of clinical signs commonly associated with chlorinated hydrocarbon toxicity, including listlessness, nervousness when approached, anorexia, and melena. Erythrocyte counts were less in mink exposed to Saginaw Bay carp than in controls, while the number of white blood cells was greater than in controls. Significant differences (p < 0.05) in the concentrations of neutrophils, lymphocytes, monocytes, and eosinophils were also found between the control and carp-fed groups, but are considered to be of limited clinical or biological importance. Hematocrit values for the mink fed the 20 and 40% carp diets were significantly less than those of mink in the control and 10% carp groups. There were no significant differences in hemoglobin concentrations among the groups. Necropsies revealed enlarged yellowish livers in many of the carp-fed mink, especially those fed the 40% carp diet. Liver, spleen, and lung weights of carp-fed mink were significantly greater than those of control mink.(ABSTRACT TRUNCATED AT 250 WORDS)
journal_name
Arch Environ Contam Toxicoljournal_title
Archives of environmental contamination and toxicologyauthors
Heaton SN,Bursian SJ,Giesy JP,Tillitt DE,Render JA,Jones PD,Verbrugge DA,Kubiak TJ,Aulerich RJdoi
10.1007/BF00212509subject
Has Abstractpub_date
1995-10-01 00:00:00pages
411-7issue
3eissn
0090-4341issn
1432-0703journal_volume
29pub_type
杂志文章abstract：:Metal pollution in the river Godavari in India, due to discharges of liquid wastes from a paper mill, has been studied for a period of two years. At the discharge point and 1 km from the point of discharge, iron, manganese, and zinc were recorded in high concentrations, whereas cadmium and chromium were observed in lo...
journal_title：Archives of environmental contamination and toxicology
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journal_title：Archives of environmental contamination and toxicology
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journal_title：Archives of environmental contamination and toxicology
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更新日期：2011-07-01 00:00:00
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journal_title：Archives of environmental contamination and toxicology
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