The impact of multidrug resistance on outcomes in ventilator-associated pneumonia.

Abstract:

:Multidrug-resistant (MDR) organisms in ventilator-associated pneumonia were found in 49 of 107 patients and were associated with home antibiotics, pre-ventilator-associated pneumonia hospital stay, and health care exposure. Overall, MDR organisms were associated with increased mortality (P = .006). On multivariate analysis, MDR status was modulated by organism class. In nonfermenting gram-negative rods, no association between MDR and mortality was found, but, in all other organisms, MDR was associated with increased mortality risk (hazard ratio, 6.15; 95% confidence interval: 1.80-21.05, P = .004).

journal_name

Am J Infect Control

authors

Tedja R,Nowacki A,Fraser T,Fatica C,Griffiths L,Gordon S,Isada C,van Duin D

doi

10.1016/j.ajic.2013.12.009

subject

Has Abstract

pub_date

2014-05-01 00:00:00

pages

542-5

issue

5

eissn

0196-6553

issn

1527-3296

pii

S0196-6553(13)01428-4

journal_volume

42

pub_type

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