Abstract:
:Similarly to a series of chronic diseases, essential arterial hypertension (HTN) may be manifested during childhood as a blood pressure (BP) reading which repeatedly rises above the 95(th) percentile of population-specific standards. Since BP tends to track along the same percentiles throughout life, children with higher BPs are more likely to become hypertensive adults. When healthy measures aimed at reducing BP (i.e. body weight reduction, aerobic physical exercise, low sodium intake) have failed, pharmacological treatment is usually required. This paper aims to undertake a review of antihypertensive pharmacological therapy in children, examining the drugs used in chronic treatment as well as those administered to treat hypertensive crisis (i.e. a BP major than 99(th) percentile of paediatric normograms). Moreover, several important differences registered in the therapeutic approach to paediatric HTN between US and European Guidelines will be underlined.
journal_name
Curr Med Chemjournal_title
Current medicinal chemistryauthors
Bassareo PP,Bassareo V,Iacovidou N,Mercuro Gdoi
10.2174/0929867321666140304093848subject
Has Abstractpub_date
2014-01-01 00:00:00pages
3121-31issue
27eissn
0929-8673issn
1875-533Xpii
CMC-EPUB-59454journal_volume
21pub_type
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