当前位置： SCI文献检索 > JOURNAL OF PEDIATRIC SURGERY期刊下所有文献 > Combined antenatal thyrotropin-releasing hormone and low-dose glucocorticoid therapy improves the pulmonary biochemical immaturity in congenital diaphragmatic hernia.

Combined antenatal thyrotropin-releasing hormone and low-dose glucocorticoid therapy improves the pulmonary biochemical immaturity in congenital diaphragmatic hernia.

Abstract：

:The lungs of patients born with severe congenital diaphragmatic hernia (CDH) are biochemically and morphologically immature. Because antenatal glucocorticoid therapy can accelerate pulmonary maturation in premature neonates who have respiratory distress syndrome, we hypothesized that it may correct the pulmonary biochemical and morphological immaturity associated with CDH. We showed in previous experimental studies that antenatal low-dose dexamethasone improved the biochemical and morphological parameters of pulmonary immaturity in rats that had severe CDH. Somatic and pulmonary growth were inhibited with high doses of dexamethasone. In the present study, we examined the effects of antenatal low-dose dexamethasone and thyrotropin-releasing hormone (TRH), alone or in combination, on the pulmonary maturation in CDH. Combined antenatal low-dose dexamethasone and TRH significantly reduced mean lung glycogen concentration (P = .001), and increased mean disaturated phosphatidylcholine content (P < .005) to better than that observed with either therapy alone, without changing mean body or lung weight. Combined TRH and low-dose glucocorticoid as an antenatal therapy may reduce the morbidity and mortality of CDH.

journal_name

J Pediatr Surg

journal_title

Journal of pediatric surgery

authors

Suen HC,Losty P,Donahoe PK,Schnitzer JJ

doi

10.1016/0022-3468(94)90348-4

subject

Has Abstract

pub_date

1994-02-01 00:00:00

pages

359-63

issue

2

eissn

0022-3468

issn

1531-5037

pii

0022-3468(94)90348-4

journal_volume

29

pub_type

杂志文章

相关文献

JOURNAL OF PEDIATRIC SURGERY文献大全
  • Prophylactic extrapleural chest drainage following repair of esophageal atresia: is it necessary?

    abstract：:In a review of 110 cases of esophageal atresia (EA) and tracheoesophageal fistula (TEF), 15 patients (13.6%) developed anastomotic leakage. All patients had extrapleural surgical exposure and prophylactic extrapleural chest drainage (PEPCD). Despite this precaution, all patients with anastomotic leaks developed a pneu...

    journal_title：Journal of pediatric surgery

    pub_type： 杂志文章

    doi：10.1016/0022-3468(92)90446-e

    authors： McCallion WA,Hannon RJ,Boston VE

    更新日期：1992-05-01 00:00:00

  • Intestinal ischemia: treatment by peritoneal lavage with oxygenated perfluorochemical.

    abstract：:Though the delivery of elemental oxygen to tissues ravaged by anaerobic infection may be useful, little data exists that suggests that such therapy may benefit ischemic tissue. We report the development of a model to test the question that peritoneal lavage with an oxygen containing solution may favorably influence oc...

    journal_title：Journal of pediatric surgery

    pub_type： 杂志文章

    doi：10.1016/s0022-3468(87)80736-4

    authors： Floyd TF,Boroughs A,Garvey C,Dasher J,Ikeda CB,Sloviter HA,Ziegler MM

    更新日期：1987-12-01 00:00:00

  • The impact of the 80-hour workweek on pediatric surgical training: an Association of Pediatric Surgery Program Directors-sponsored study.

    abstract：BACKGROUND/PURPOSE:The aim of this study was to determine the preliminary impact of work hour regulations on pediatric surgical training. METHODS:An anonymous survey was sent to all program directors (PDs) and fellows to identify changes in pediatric surgery fellowship programs. RESULTS:Ninety-three percent of progra...

    journal_title：Journal of pediatric surgery

    pub_type： 杂志文章

    doi：10.1016/j.jpedsurg.2004.09.014

    authors： Henry MC,Silverman BL,Moss RL

    更新日期：2005-01-01 00:00:00

  • Early experience with the use of rhomboid excision and Limberg flap in 16 adolescents with pilonidal disease.

    abstract：BACKGROUND:Rhomboid excision with Limberg flap (RELF) repair has been shown to be effective in the management of pilonidal disease (PD) in adults. Wide excision allows complete removal of diseased tissue, and the rotational flap allows tensionless coverage as well as helps flatten the natal crease, which is believed to...

    journal_title：Journal of pediatric surgery

    pub_type： 杂志文章

    doi：10.1016/j.jpedsurg.2008.11.033

    authors： Yamout SZ,Caty MG,Lee YH,Lau ST,Escobar MA,Glick PL

    更新日期：2009-08-01 00:00:00

  • Pediatric surgery on the Internet: is the truth out there?

    abstract：BACKGROUND:The enormous amount of unmonitored medical information on the Internet prompted this investigation into the quality of pediatric surgery information on the Internet. METHODS:The Internet was searched for information on diaphragmatic hernia (CDH), abdominal wall defects (AWD), pediatric inguinal hernia (IH),...

    journal_title：Journal of pediatric surgery

    pub_type： 杂志文章

    doi：10.1053/jpsu.2000.8723

    authors： Chen LE,Minkes RK,Langer JC

    更新日期：2000-08-01 00:00:00

  • Robotic fundoplication in children: resident teaching and a single institutional review of our first 50 patients.

    abstract：BACKGROUND:Robotic surgery is a new technology that may eventually replace laparoscopy in treating many surgical issues in children. Resident education using robotic surgery has been a concern for many institutions. We present our first 50 consecutive robotic fundoplications in children and our teaching experience with...

    journal_title：Journal of pediatric surgery

    pub_type： 杂志文章

    doi：10.1016/j.jpedsurg.2007.08.022

    authors： Meehan JJ,Meehan TD,Sandler A

    更新日期：2007-12-01 00:00:00

  • Non-operative management of early, acute appendicitis in children: is it safe and effective?

    abstract：PURPOSE:The purpose of this study was to determine if early, acute appendicitis in children can be safely and effectively managed with antibiotics alone. METHODS:A retrospective review was performed of children (<18 yrs) treated non-operatively (NOM) for early, acute appendicitis since May 2012. These were compared to...

    journal_title：Journal of pediatric surgery

    pub_type： 杂志文章

    doi：10.1016/j.jpedsurg.2014.02.071

    authors： Armstrong J,Merritt N,Jones S,Scott L,Bütter A

    更新日期：2014-05-01 00:00:00

  • Prenatal diagnosis of mediastinal neurentric cyst with an intraspinal component.

    abstract：:Mediastinal neurenteric cysts are the least common types of the bronchopulmonary foregut malformations, and their antenatal diagnosis is rare. We report a case of mediastinal neurenteric cyst diagnosed on antenatal ultrasonography at 28 weeks' gestation. A small intraspinal component and vertebral segmentation anomali...

    journal_title：Journal of pediatric surgery

    pub_type： 杂志文章

    doi：10.1016/j.jpedsurg.2010.03.007

    authors： Gadodia A,Sharma R,Jeyaseelan N,Aggarwala S,Gupta P

    更新日期：2010-06-01 00:00:00

  • Dynamic MRI (dMRI) as a guide to therapy in children and adolescents with persistent full thickness rectal prolapse: a single centre review.

    abstract：INTRODUCTION:Full thickness rectal prolapse (FTRP) tends to be self-limiting in children and is usually managed expectantly. However, it may persist and therefore requires surgical correction. There is no consensus upon operative management, and no one procedure has uniformly good outcomes. The aim of this study was to...

    journal_title：Journal of pediatric surgery

    pub_type： 杂志文章

    doi：10.1016/j.jpedsurg.2012.08.006

    authors： Campbell AM,Murphy J,Charlesworth PB,Bhan C,Jarvi K,Power N,Ward HC,Williams NS

    更新日期：2013-03-01 00:00:00

  • One-year outcomes of congenital diaphragmatic hernia repair: Factors associated with recurrence and complications.

    abstract：PURPOSE:Congenital diaphragmatic hernia (CDH) is a congenital anomaly associated with lifelong multisystem morbidity. This study sought to identify factors contributing to hospital readmission after CDH repair. METHODS:The Nationwide Readmissions Database from 2010 to 2014 was used to identify patients with CDH who un...

    journal_title：Journal of pediatric surgery

    pub_type： 杂志文章

    doi：10.1016/j.jpedsurg.2020.09.018

    authors： Cioci AC,Urrechaga EM,Parreco J,Remer LF,Cowan M,Perez EA,Sola JE,Thorson CM

    更新日期：2020-10-01 00:00:00

  • Preputial unfurling to correct the buried penis.

    abstract：:Recognition of the buried penis is necessary both to ensure its proper management and to avoid performance of a standard circumcision, which can result in penile degloving. We describe a simple technique of unfurling the prepuce which provides adequate functional and cosmetic replacement for the penile shaft skin. ...

    journal_title：Journal of pediatric surgery

    pub_type： 杂志文章

    doi：10.1016/0022-3468(86)90007-2

    authors： Donahoe PK,Keating MA

    更新日期：1986-12-01 00:00:00

  • First clinical application of an automatic VA-ECMO system using artificial hearts as a blood pump.

    abstract：:A new extracorporeal membrane oxygenation (ECMO) circuit using air-driven artificial hearts as a blood pump was first applied on a newborn with congenital diaphragmatic hernia. ECMO was continued for 67 hours 36 minutes with no mechanical trouble. Since the artificial hearts changed their output automatically in propo...

    journal_title：Journal of pediatric surgery

    pub_type： 杂志文章

    doi：10.1016/0022-3468(93)90334-h

    authors： Ito T,Seo T,Ishiguro T,Takagi H

    更新日期：1993-06-01 00:00:00

  • Necrotizing fasciitis: a rare complication of hypospadias surgery in a child.

    abstract：:Necrotizing fasciitis is a rapidly progressive soft tissue infection involving the skin, subcutaneous tissue, and superficial fascia. It is a rare entity in the pediatric population. The specific etiologic factors that contribute to the establishment of necrotizing fasciitis in children are not evident. It may occur a...

    journal_title：Journal of pediatric surgery

    pub_type： 杂志文章

    doi：10.1016/j.jpedsurg.2005.01.024

    authors： Luo CC,Chin Chao H,Hsun Chiu C

    更新日期：2005-04-01 00:00:00

  • Interpretation of radiologic abnormalities in patients with chronically infected ingrown toenails with regard to a possible exogenic osteomyelitis.

    abstract：BACKGROUND:Chronic infection of ingrown toenails may lead to exogenous osteomyelitis. Therefore, plain x-rays are commonly taken in children with significant inflammation. We evaluated the preoperative radiologic findings and their clinical significance, especially with regard to exogenic osteomyelitis. PATIENTS AND M...

    journal_title：Journal of pediatric surgery

    pub_type： 杂志文章

    doi：10.1016/j.jpedsurg.2009.05.032

    authors： Majcen ME,Wilfinger CC,Pilhatsch A

    更新日期：2009-11-01 00:00:00

  • Delayed blind-pouch apposition, guide wire placement, and nonoperative establishment of luminal continuity in a child with long gap esophageal atresia.

    abstract：:Delayed primary esophago-esophagostomy is the most physiologically attractive approach to establish luminal continuity in children with pure esophageal atresia. However, excessive tension on the mobilized esophageal ends can lead to anastomotic separation and severe leakage. To circumvent these complications, the blin...

    journal_title：Journal of pediatric surgery

    pub_type： 杂志文章

    doi：10.1016/s0022-3468(03)00120-9

    authors： Gauderer MW

    更新日期：2003-06-01 00:00:00

  • Giant cutaneous hemangioma associated with axillary arteriovenous fistula causing congestive heart failure in the newborn infant.

    abstract：:Although histopathologically benign, cutaneous hemangiomas may be pathophysiologically malignant if they are associated with significant arteriovenous malformation that is hemodynamically compromising. Rapid surgical intervention may be required to prevent clinical deterioration from congestive heart failure as in the...

    journal_title：Journal of pediatric surgery

    pub_type： 杂志文章

    doi：10.1016/s0022-3468(87)80270-1

    authors： Lofland GK,Filston HC

    更新日期：1987-05-01 00:00:00

  • Capsulectomy: a cure for the page kidney.

    abstract：:Hypertension is a known complication after renal trauma. The cause of posttraumatic hypertension can be renal scarring, infarction, hydonephrosis, infection, vascular injury, and parenchymal compression. The authors report on the case of a 16-year-old boy who experienced hypertension after blunt renal trauma. He had a...

    journal_title：Journal of pediatric surgery

    pub_type： 杂志文章

    doi：10.1016/s0022-3468(97)90630-8

    authors： Moriarty KP,Lipkowitz GS,Germain MJ

    更新日期：1997-06-01 00:00:00

  • Foreign-body ingestion in children: experience with 1,265 cases.

    abstract：BACKGROUND/PURPOSE:This study aims to elucidate the clinical presentation, the effectiveness of investigations, and treatment of foreign body ingestion in children and to formulate an algorithm of management. METHODS:The records of children admitted to a single institution who had a history of foreign body ingestion o...

    journal_title：Journal of pediatric surgery

    pub_type： 杂志文章

    doi：10.1016/s0022-3468(99)90106-9

    authors： Cheng W,Tam PK

    更新日期：1999-10-01 00:00:00

  • How to achieve a successful Malone antegrade continence enema.

    abstract：BACKGROUND/PURPOSE:The Malone antegrade continence enema (MACE) has proved invaluable in the management of children with faecal incontinence. The authors have reviewed their experience in depth to try and ascertain why some MACEs fail. METHODS:The records of 31 children who had a MACE procedure between 1990 and 1995 w...

    journal_title：Journal of pediatric surgery

    pub_type： 杂志文章

    doi：10.1016/s0022-3468(98)90381-5

    authors： Curry JI,Osborne A,Malone PS

    更新日期：1998-01-01 00:00:00

  • Heterotopic gastric mucosa of the upper esophagus following repair of esophageal atresia with tracheoesophageal fistula.

    abstract：:A term female newborn underwent uncomplicated repair of esophageal atresia with tracheoesophageal fistula (type C) then coarctation of the aorta. Subsequently, she developed symptomatic esophageal strictures, which required serial dilations. In addition, she suffered feeding intolerance from esophageal dysmotility and...

    journal_title：Journal of pediatric surgery

    pub_type： 杂志文章

    doi：10.1016/j.jpedsurg.2010.09.010

    authors： Tran S,Misra S,Bittner JG 4th,Pipkin W,Hatley R,Howell CG

    更新日期：2011-01-01 00:00:00

  • Laparoscopic Ladd's procedure for malrotation in infants and children is still a controversial approach.

    abstract：BACKGROUND:Open Ladd's procedure is the gold standard for the correction of intestinal malrotation and laparoscopic approach remains controversial. This study aimed to evaluate our experience in laparoscopic management of malrotation. METHODS:Single center retrospective study including patients who underwent a laparos...

    journal_title：Journal of pediatric surgery

    pub_type： 杂志文章

    doi：10.1016/j.jpedsurg.2018.09.023

    authors： Arnaud AP,Suply E,Eaton S,Blackburn SC,Giuliani S,Curry JI,Cross KM,De Coppi P

    更新日期：2019-09-01 00:00:00

  • Association of gastroschisis and choledochal cyst.

    abstract：:Two infants are described who presented in the neonatal period with a direct hyperbilirubinemia. This was initially presumed to be because of the diagnosis of gastroschisis and the prolonged use of parenteral nutrition. However, both infants were eventually found to have an associated choledochal cyst. The cases are a...

    journal_title：Journal of pediatric surgery

    pub_type： 杂志文章

    doi：10.1016/j.jpedsurg.2008.12.005

    authors： Serber J,Stranzinger E,Geiger JD,Teitelbaum DH

    更新日期：2009-03-01 00:00:00

  • The value of circular myotomy for esophageal atresia.

    abstract：:The joining of widely separated proximal and distal esophageal segments in esophageal atresia remains a challenging problem. Livaditis introduced the operation of circular myotomy as an effective means of bridging such a wide gap. Three babies with esophageal atresia were successfully treated in this manner at the Hos...

    journal_title：Journal of pediatric surgery

    pub_type： 杂志文章

    doi：10.1016/s0022-3468(78)80453-9

    authors： Vizas D,Ein SH,Simpson JS

    更新日期：1978-08-01 00:00:00

  • Histopathologic findings of advanced neuroblastoma after intensive induction chemotherapy.

    abstract：BACKGROUND:Histopathologic findings of advanced neuroblastoma after intensive induction chemotherapy have not been studied well. METHODS:In the present study, all of the surgical specimens from 19 patients who had advanced abdominal neuroblastoma and were pretreated intensively with the protocol of the Study Group of ...

    journal_title：Journal of pediatric surgery

    pub_type： 杂志文章

    doi：10.1016/s0022-3468(97)90467-x

    authors： Miyauchi J,Matsuoka K,Oka T,Kamii Y,Honna T,Bessho F,Sasaki S,Melanowska J,Tsuchida Y

    更新日期：1997-11-01 00:00:00

  • Is early response to portoenterostomy predictive of long-term outcome for patients with biliary atresia?

    abstract：PURPOSE:Therapy for biliary atresia (BA) typically involves portoenterostomy (PE). In light of the development of liver transplantation (LT) as an option for therapy in infancy, the authors reviewed their experience to determine factors that might predict the requirement for LT. METHODS:Cases of BA diagnosed between S...

    journal_title：Journal of pediatric surgery

    pub_type： 杂志文章

    doi：10.1016/s0022-3468(96)90130-x

    authors： Yanchar NL,Shapiro AM,Sigalet DL

    更新日期：1996-06-01 00:00:00

  • Trauma induced left ventricular apical ballooning syndrome in a 15 year old: a rare case of Tako-tsubo cardiomyopathy.

    abstract：:We present a case of a 15 year old girl who developed transient left ventricular apical ballooning syndrome, Tako-tsubo cardiomyopathy, after a significant motor vehicle accident. On post-trauma day three she developed heart failure with mid-to-apical left ventricular wall dysfunction with an EF of 10%-15%. The patien...

    journal_title：Journal of pediatric surgery

    pub_type： 杂志文章

    doi：10.1016/j.jpedsurg.2013.01.042

    authors： Krpata DM,Barksdale EM Jr

    更新日期：2013-04-01 00:00:00

  • Anoplasty for low anorectal malformation.

    abstract：BACKGROUND:The presence of a slightly anterior, stenotic anus is a low anorectal malformation. It is a type of rectoperineal fistula. The cardinal symptoms are constipation and straining at stool. Hendren described a technically simple anoplasty for this condition in 1978. Controversy about terminology has led to a lac...

    journal_title：Journal of pediatric surgery

    pub_type： 杂志文章

    doi：10.1016/j.jpedsurg.2016.03.007

    authors： Whyte C,Canty TG,Smith J,Melody K

    更新日期：2016-10-01 00:00:00

  • New techniques in the diagnosis and operative management of Siamese twins.

    abstract：:New techniques of 2-D sonography and radionucleotide Disofenin scanning allowed noninvasive evaluation of thoracoomphalopagus Siamese twins and successful separation at four days of age. Twin girls joined at the lower sternum and upper abdomen and weighing 15 lbs, were transferred at five hours of age after caesarian-...

    journal_title：Journal of pediatric surgery

    pub_type： 杂志文章

    doi：10.1016/s0022-3468(83)80184-5

    authors： Miller D,Colombani P,Buck JR,Dudgeon DL,Haller JA Jr

    更新日期：1983-08-01 00:00:00

  • Overexpression of Fas-ligand by neuroblastoma: a novel mechanism of tumor-cell killing.

    abstract：BACKGROUND/PURPOSE:Binding of Fas ligand (Fas-L) to the membrane-bound Fas receptor incites a series of intracellular events that results in programmed cell death or apoptosis. Although this apoptotic phenomenon plays a key role in down-regulating cytotoxic T cells, the authors have shown previously that pancreatic bet...

    journal_title：Journal of pediatric surgery

    pub_type： 杂志文章

    doi：10.1016/s0022-3468(00)90044-7

    authors： Takamizawa S,Okamoto S,Wen J,Bishop W,Kimura K,Sandler A

    更新日期：2000-02-01 00:00:00

  • Pediatric genital burns: a 15-year retrospective analysis of outcomes at a level 1 burn center.

    abstract：BACKGROUND/PURPOSE:Burns involving the genitalia and perineum are commonly seen in the context of extensive total body surface area (TBSA) burns and rarely as isolated injuries because of protection provided by the thighs and the abdomen. Genital burns usually result in extended hospital stays and are accompanied by se...

    journal_title：Journal of pediatric surgery

    pub_type： 杂志文章

    doi：10.1016/j.jpedsurg.2011.02.050

    authors： Klaassen Z,Go PH,Mansour EH,Marano MA,Petrone SJ,Houng AP,Chamberlain RS

    更新日期：2011-08-01 00:00:00