Abstract:
:The airway occlusion techniques for assessing passive respiratory mechanics have become well established methods in fullterm neonates and older infants. The single breath technique (SBT) is frequently used for assessing lung function in intubated infants on neonatal intensive care units. However, less is known about the reliability of these quick and noninvasive techniques in healthy preterm infants. The aim of this study was to evaluate these methods in healthy unintubated preterm infants to facilitate both establishment of reference values and more meaningful interpretation of lung function assessments in the neonatal unit. Forty-seven studies were attempted in 31 healthy preterm infants (gestational age 29-36 weeks; body weight 1.88 +/- 0.28 kg; mean +/- SD) during the first 2 weeks of life, using both the multiple occlusion technique (MOT) and the SBT. Whereas technically acceptable respiratory system compliance (Crs) data from either the MOT or the SBT were obtained on 37 occasions in 25 infants, satisfactory results from both techniques were achieved only on 22 occasions. In these infants mean +/- SD Crs was 28.1 +/- 5.2 mL kPa-1 when assessed by MOT and 29.1 +/- 6.0 mL kPa-1 when using the SBT. The mean difference between technically satisfactory paired Crs values obtained with MOT and SBT was less than 5% (range, +28 to -18%). By contrast, in infants in whom data were invalidated as a result of expiratory airflow braking, failure to relax or instability of the end-expiratory level, gross discrepancies occurred between the techniques.(ABSTRACT TRUNCATED AT 250 WORDS)
journal_name
Pediatr Pulmonoljournal_title
Pediatric pulmonologyauthors
Gappa M,Rabbette PS,Costeloe KL,Stocks Jdoi
10.1002/ppul.1950150508subject
Has Abstractpub_date
1993-05-01 00:00:00pages
304-11issue
5eissn
8755-6863issn
1099-0496journal_volume
15pub_type
杂志文章abstract::We assessed the safety and use of induced sputum (IS) in children with cystic fibrosis (CF). Forty-eight children (19 males) with CF, mean age 12.6 (range, 7.3-17.0) years and median forced expired volume in 1 sec (FEV(1)) 48% (range, 14-77%) predicted were recruited. Patients spontaneously expectorated sputum and the...
journal_title:Pediatric pulmonology
pub_type: 杂志文章
doi:10.1002/ppul.10226
更新日期:2003-04-01 00:00:00
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journal_title:Pediatric pulmonology
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更新日期:2015-12-01 00:00:00
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journal_title:Pediatric pulmonology
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journal_title:Pediatric pulmonology
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journal_title:Pediatric pulmonology
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journal_title:Pediatric pulmonology
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journal_title:Pediatric pulmonology
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journal_title:Pediatric pulmonology
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journal_title:Pediatric pulmonology
pub_type: 杂志文章
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更新日期:1996-06-01 00:00:00
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journal_title:Pediatric pulmonology
pub_type: 杂志文章,评审
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journal_title:Pediatric pulmonology
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journal_title:Pediatric pulmonology
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更新日期:2012-05-01 00:00:00
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journal_title:Pediatric pulmonology
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doi:10.1002/(SICI)1099-0496(199601)21:1<11::AID-PPUL2>
更新日期:1996-01-01 00:00:00
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pub_type: 临床试验,杂志文章,随机对照试验
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pub_type: 临床试验,杂志文章
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pub_type: 杂志文章
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pub_type: 杂志文章
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更新日期:2013-01-01 00:00:00
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journal_title:Pediatric pulmonology
pub_type: 杂志文章,评审
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更新日期:1999-10-01 00:00:00
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pub_type: 杂志文章
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