Management of neonatal seizures.

Abstract:

:Seizures in the neonatal period are usually concomitants of serious neurological disease. The convulsive phenomena take certain distinctive and often subtle forms because of the status of the neuroanatomical and neurophysiological development of the neonatal brain. The predominant etiological process is hypoxic-ischemic encephalopathy, but intracranial hemorrhage, intracranial infection, development defects and metabolic disorders are also responsible for a considerable proportion of cases. Prognosis is related primarily to the neurological disease that underlies the seizures. Treatment may be specific for the underlying disorder, e.g., glucose, calcium, magnesium, pyridoxine, but whatever the cause, urgent control of the convulsions is important because they may have deleterious consequences. Phenobarbital is the single, most important anticonvulsant in the management of neonatal seizures.

journal_name

Crit Care Med

journal_title

Critical care medicine

authors

Volpe JJ

doi

10.1097/00003246-197701000-00008

subject

Has Abstract

pub_date

1977-01-01 00:00:00

pages

43-9

issue

1

eissn

0090-3493

issn

1530-0293

journal_volume

5

pub_type

杂志文章
  • 1,25-Dihydroxyvitamin D fluctuations in cardiac surgery are related to age and clinical outcome*.

    abstract:OBJECTIVE:To investigate the interrelationship between cardiac surgery, age, circulating concentrations of the vitamin D hormone 1,25-dihydroxyvitamin D, and clinical outcome. DESIGN:Prospective, monocentric, two-arm parallel study. SETTING:Tertiary Heart and Diabetes Center in the Federal State of North Rhine-Westph...

    journal_title:Critical care medicine

    pub_type: 临床试验,杂志文章

    doi:10.1097/CCM.0b013e31824e8c42

    authors: Börgermann J,Lazouski K,Kuhn J,Dreier J,Schmidt M,Gilis-Januszewski T,Knabbe C,Gummert JF,Zittermann A

    更新日期:2012-07-01 00:00:00

  • Death in the ICU: does the patient predict his own demise?

    abstract::Critically ill patients who fear impending death may die suddenly. We studied prospectively the incidence of death in critically ill surgical patients who articulated the fear that they were about to die. Physiologic, environmental, and behavioral correlates which might influence perceptions of impending death were ex...

    journal_title:Critical care medicine

    pub_type: 杂志文章

    doi:10.1097/00003246-198607000-00005

    authors: Poulton TJ,Butdorf MB

    更新日期:1986-07-01 00:00:00

  • Ventilator-Associated Events: Prevalence, Outcome, and Relationship With Ventilator-Associated Pneumonia.

    abstract:OBJECTIVES:Centers for Disease Control and Prevention built up new surveillance paradigms for the patients on mechanical ventilation and the ventilator-associated events, comprising ventilator-associated conditions and infection-related ventilator-associated complications. We assess 1) the current epidemiology of venti...

    journal_title:Critical care medicine

    pub_type: 杂志文章,多中心研究

    doi:10.1097/CCM.0000000000001091

    authors: Bouadma L,Sonneville R,Garrouste-Orgeas M,Darmon M,Souweine B,Voiriot G,Kallel H,Schwebel C,Goldgran-Toledano D,Dumenil AS,Argaud L,Ruckly S,Jamali S,Planquette B,Adrie C,Lucet JC,Azoulay E,Timsit JF,OUTCOMEREA Study

    更新日期:2015-09-01 00:00:00

  • Evaluation of sublingual and gut mucosal microcirculation in sepsis: a quantitative analysis.

    abstract:OBJECTIVE:To determine the relationship between sublingual and intestinal mucosal microcirculatory perfusion. DESIGN:Observational, experimental study. SETTING:University-affiliated large animal laboratory. SUBJECTS:Ten fasted, anesthetized, mechanically ventilated, male pigs randomized to a sham group (n = 3) or to...

    journal_title:Critical care medicine

    pub_type: 杂志文章

    doi:10.1097/CCM.0b013e3181b029c1

    authors: Verdant CL,De Backer D,Bruhn A,Clausi CM,Su F,Wang Z,Rodriguez H,Pries AR,Vincent JL

    更新日期:2009-11-01 00:00:00

  • Dose-related hemodynamic and renal effects of dopamine in septic shock.

    abstract::offstudied hemodynamic and renal effects of increasing the dosage of dopamine (DP) by 5 micrograms/kg X min, in 7 patients with peritonitis and clinical findings of septic shock, all of whom were already receiving variable dosages of DP. Stroke index (SI) (p less than .01), except in 3 cases, and mean arterial pressur...

    journal_title:Critical care medicine

    pub_type: 杂志文章

    doi:10.1097/00003246-198401000-00006

    authors: de la Cal MA,Miravalles E,Pascual T,Esteban A,Ruiz-Santana S

    更新日期:1984-01-01 00:00:00

  • Clinical experience with tight glucose control by intensive insulin therapy.

    abstract:OBJECTIVE:To describe the current status and the clinical data related to the effects of tight glucose control by intensive insulin therapy in critically ill patients. DESIGN:Review article. SETTING:University hospital. PATIENTS:Medical and surgical critically ill patients in whom a correlation between blood glucose...

    journal_title:Critical care medicine

    pub_type: 杂志文章,评审

    doi:10.1097/01.CCM.0000278046.24345.C7

    authors: Preiser JC,Devos P

    更新日期:2007-09-01 00:00:00

  • Noninvasive pulse oximetry in children with cyanotic congenital heart disease.

    abstract::Arterial oxygen saturation, determined noninvasively by pulse oximetry in 32 pediatric patients with cyanotic congenital heart disease (CHD), was compared with oxygen saturation measured by a cooximeter in simultaneously obtained arterial blood samples. The patients were studied in the cardiac catheterization laborato...

    journal_title:Critical care medicine

    pub_type: 杂志文章

    doi:10.1097/00003246-198711000-00015

    authors: Boxer RA,Gottesfeld I,Singh S,LaCorte MA,Parnell VA Jr,Walker P

    更新日期:1987-11-01 00:00:00

  • Value and cost of teaching hospitals: a prospective, multicenter, inception cohort study.

    abstract:OBJECTIVE:To examine variations in case-mix, structure, resource use, and outcome performance among teaching and nonteaching intensive care units (ICU). DESIGN:Prospective inception cohort study. PATIENTS:A consecutive sample of 15,297 patients at 35 hospitals, which compared 8,269 patients admitted to 20 teaching IC...

    journal_title:Critical care medicine

    pub_type: 杂志文章,多中心研究

    doi:10.1097/00003246-199310000-00009

    authors: Zimmerman JE,Shortell SM,Knaus WA,Rousseau DM,Wagner DP,Gillies RR,Draper EA,Devers K

    更新日期:1993-10-01 00:00:00

  • Hypophosphatemia induced by mechanical ventilation in patients with chronic obstructive pulmonary disease.

    abstract::The aim of this study was to assess prospectively the variations of serum phosphorus concentration (P) after onset of mechanical ventilation (MV) in patients with chronic obstructive pulmonary disease (COPD) and acute respiratory acidosis. In 14 COPD patients, we measured P, PaCO2, and pH, immediately before MV (H0), ...

    journal_title:Critical care medicine

    pub_type: 杂志文章

    doi:10.1097/00003246-198911000-00005

    authors: Laaban JP,Grateau G,Psychoyos I,Laromiguière M,Vuong TK,Rochemaure J

    更新日期:1989-11-01 00:00:00

  • A multicenter, randomized trial of noninvasive ventilation with helium-oxygen mixture in exacerbations of chronic obstructive lung disease.

    abstract:OBJECTIVE:To assess the effect of a helium-oxygen mixture on intubation rate and clinical outcomes during noninvasive ventilation in acute exacerbation of chronic obstructive pulmonary disease. DESIGN:Multicenter, prospective, randomized, controlled trial. SETTING:Seven intensive care units. PATIENTS:A total of 204 ...

    journal_title:Critical care medicine

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1097/CCM.0b013e3181b78abe

    authors: Maggiore SM,Richard JC,Abroug F,Diehl JL,Antonelli M,Sauder P,Mancebo J,Ferrer M,Lellouche F,Lecourt L,Beduneau G,Brochard L

    更新日期:2010-01-01 00:00:00

  • Prediction of Large Vessel Occlusions in Acute Stroke: National Institute of Health Stroke Scale Is Hard to Beat.

    abstract:OBJECTIVES:Endovascular treatment for acute ischemic stroke with a large vessel occlusion was recently shown to be effective. We aimed to develop a score capable of predicting large vessel occlusion eligible for endovascular treatment in the early hospital management. DESIGN:Retrospective, cohort study. SETTING:Two t...

    journal_title:Critical care medicine

    pub_type: 杂志文章

    doi:10.1097/CCM.0000000000001630

    authors: Vanacker P,Heldner MR,Amiguet M,Faouzi M,Cras P,Ntaios G,Arnold M,Mattle HP,Gralla J,Fischer U,Michel P

    更新日期:2016-06-01 00:00:00

  • Reversal of late septic shock with supraphysiologic doses of hydrocortisone.

    abstract:OBJECTIVES:Preliminary studies have suggested that low doses of corticosteroids might rapidly improve hemodynamics in late septic shock treated with catecholamines. We examined the effect of hydrocortisone on shock reversal, hemodynamics, and survival in this particular setting. DESIGN:Prospective, randomized, double-...

    journal_title:Critical care medicine

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1097/00003246-199804000-00010

    authors: Bollaert PE,Charpentier C,Levy B,Debouverie M,Audibert G,Larcan A

    更新日期:1998-04-01 00:00:00

  • Hemodynamic, renal, and hormonal actions of aprotinin in an ovine model of septic shock.

    abstract:BACKGROUND AND METHODS:Previous studies documented activation of protease enzymes such as the plasma kallikrein-kinin system in endotoxemia and sepsis, both in experimental animals and in patients. We investigated the actions of aprotinin (a protease inhibitor that binds to plasma kallikrein) on systemic hemodynamics a...

    journal_title:Critical care medicine

    pub_type: 杂志文章

    doi:10.1097/00003246-199208000-00012

    authors: Cumming AD,Nimmo GR

    更新日期:1992-08-01 00:00:00

  • Liver function and morphology after resuscitation from severe hemorrhagic shock with hemoglobin solutions or autologous blood.

    abstract:OBJECTIVE:To test the effects of three hemoglobin solutions on liver function and hepatic morphology after resuscitation from severe hemorrhagic shock. DESIGN:Prospective study. SETTING:Laboratory. SUBJECTS:Thirty-three beagle dogs. INTERVENTION:Hemorrhagic shock was induced in anesthetized dogs by removal of blood...

    journal_title:Critical care medicine

    pub_type: 杂志文章

    doi:10.1097/00003246-199604000-00019

    authors: Eldridge J,Russell R,Christenson R,Sakamoto R,Williams J,Parr M,Trump B,Delaney P,Mackenzie CF

    更新日期:1996-04-01 00:00:00

  • End-tidal CO2 as a guide to successful cardiopulmonary resuscitation: a preliminary report.

    abstract::Utilizing a well-established porcine model of cardiac arrest, we found that end-tidal CO2 concentration (ETCO2) strikingly decreased to approximately 24% of control levels, immediately after cardiac arrest and before precordial compression. During precordial compression, ETCO2 progressively increased to 46% of control...

    journal_title:Critical care medicine

    pub_type: 杂志文章

    doi:10.1097/00003246-198511000-00012

    authors: Trevino RP,Bisera J,Weil MH,Rackow EC,Grundler WG

    更新日期:1985-11-01 00:00:00

  • A simple method for diagnosing pneumonia in intubated or tracheostomized patients.

    abstract::A safe, simple, reliable technique for sampling uncontaminated peripheral bronchial secretions in patients with endotracheal tubes has been developed. It is easily performed and requires no special training or equipment. This report summarizes the techniques's usefulness in providing diagnostic samples of peripheral a...

    journal_title:Critical care medicine

    pub_type: 杂志文章

    doi:10.1097/00003246-197703000-00003

    authors: Matthew EB,Holstrom FM,Kaspar RL

    更新日期:1977-03-01 00:00:00

  • Use of bispectral electroencephalogram monitoring to assess neurologic status in unsedated, critically ill patients.

    abstract:OBJECTIVE:To test whether spectral indices derived from the electroencephalogram (EEG), and especially the bispectral index (BIS), can be used as measures of neurologic status in unsedated, critically ill patients. DESIGN:Prospective, observational study. SETTING:Medical intensive care unit (ICU) of a university-affi...

    journal_title:Critical care medicine

    pub_type: 杂志文章

    doi:10.1097/00003246-200110000-00024

    authors: Gilbert TT,Wagner MR,Halukurike V,Paz HL,Garland A

    更新日期:2001-10-01 00:00:00

  • Medical complications of aneurysmal subarachnoid hemorrhage: a report of the multicenter, cooperative aneurysm study. Participants of the Multicenter Cooperative Aneurysm Study.

    abstract:OBJECTIVES:This report examines the frequency, type, and prognostic factors of medical (nonneurologic) complications after subarachnoid hemorrhage in a large, prospective study. The influences of contemporary neurosurgical, neurological, and critical care practice on mortality and morbidity rates after aneurysmal subar...

    journal_title:Critical care medicine

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1097/00003246-199506000-00004

    authors: Solenski NJ,Haley EC Jr,Kassell NF,Kongable G,Germanson T,Truskowski L,Torner JC

    更新日期:1995-06-01 00:00:00

  • Antibiotic dosing during sustained low-efficiency dialysis: special considerations in adult critically ill patients.

    abstract:OBJECTIVE:To address issues of antibiotic dosing during sustained low-efficiency dialysis by using available pharmacokinetic data, intermittent and continuous renal replacement therapy dialysis guidelines, and our experience with sustained low-efficiency dialysis. DATA RESOURCES:Published clinical trials, case reports...

    journal_title:Critical care medicine

    pub_type: 杂志文章,评审

    doi:10.1097/CCM.0b013e318206c3b2

    authors: Bogard KN,Peterson NT,Plumb TJ,Erwin MW,Fuller PD,Olsen KM

    更新日期:2011-03-01 00:00:00

  • Colloid solution therapy of experimental ischemic intestinal shock in rats.

    abstract::This study evaluated the effects of varying colloid concentrations and infusion volumes on survival and plasma volume expansion in rats subjected to an intestinal ischemic shock. Up to 10% solutions of albumin and dextran-40 in lactated Ringer's solution, infused over a 6-h period, had the same effects on hematocrit (...

    journal_title:Critical care medicine

    pub_type: 杂志文章

    doi:10.1097/00003246-198509000-00003

    authors: Dawidson I,Ottosson J,Reisch J

    更新日期:1985-09-01 00:00:00

  • Suspended animation for delayed resuscitation from prolonged cardiac arrest that is unresuscitable by standard cardiopulmonary-cerebral resuscitation.

    abstract::Standard cardiopulmonary-cerebral resuscitation fails to achieve restoration of spontaneous circulation in approximately 50% of normovolemic sudden cardiac arrests outside hospitals and in essentially all victims of penetrating truncal trauma who exsanguinate rapidly to cardiac arrest. Among cardiopulmonary-cerebral r...

    journal_title:Critical care medicine

    pub_type: 杂志文章,评审

    doi:10.1097/00003246-200011001-00012

    authors: Safar P,Tisherman SA,Behringer W,Capone A,Prueckner S,Radovsky A,Stezoski WS,Woods RJ

    更新日期:2000-11-01 00:00:00

  • Pentoxifylline improves tissue oxygenation following anesthesia and operation.

    abstract::Pentoxifylline has been shown to increase red blood cell malleability, thus increasing capillary blood flow in a number of disease states. The present study was undertaken to determine whether pentoxifylline might improve tissue oxygenation after anesthesia and during an operation in rats. Rats were anesthetized and d...

    journal_title:Critical care medicine

    pub_type: 杂志文章

    doi:10.1097/00003246-198702000-00001

    authors: Soliman MH,O'Neal K,Waxman K

    更新日期:1987-02-01 00:00:00

  • Pretransport Pediatric Risk of Mortality (PRISM) score underestimates the requirement for intensive care or major interventions during interhospital transport.

    abstract:OBJECTIVE:To test the hypothesis that a pretransport Pediatric Risk of Mortality (PRISM) score underestimates the requirement for both intensive care and interventions during pediatric interhospital transport. DESIGN:Prospective, descriptive study. SETTING:All children were treated in a regional hospital and then tra...

    journal_title:Critical care medicine

    pub_type: 杂志文章

    doi:10.1097/00003246-199401000-00020

    authors: Orr RA,Venkataraman ST,Cinoman MI,Hogue BL,Singleton CA,McCloskey KA

    更新日期:1994-01-01 00:00:00

  • Comparison of the renal effects of low to high doses of dopamine and dobutamine in critically ill patients: a single-blind randomized study.

    abstract:OBJECTIVE:The renal effects of dopamine in critically ill patients remain controversial. Low-dose dobutamine has been reported to improve renal function. We compared the effects of various doses of dopamine and dobutamine on renal function in critically ill patients. DESIGN:Prospective, single-blind, randomized study....

    journal_title:Critical care medicine

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/00003246-200004000-00002

    authors: Ichai C,Soubielle J,Carles M,Giunti C,Grimaud D

    更新日期:2000-04-01 00:00:00

  • Intestinal ischemia/reperfusion enhances microglial activation and induces cerebral injury and memory dysfunction in rats.

    abstract:OBJECTIVE:The mortality of critically ill patients associated with intestinal ischemia/reperfusion remains very high, which results from multiorgan dysfunction or failure due to intestinal injury induced by intestinal ischemia/reperfusion. This study was carried out to investigate whether intestinal ischemia/reperfusio...

    journal_title:Critical care medicine

    pub_type: 杂志文章

    doi:10.1097/CCM.0b013e3182546855

    authors: Zhou J,Huang WQ,Li C,Wu GY,Li YS,Wen SH,Lei WL,Liu KX

    更新日期:2012-08-01 00:00:00

  • Morphine Dose Optimization in Critically Ill Pediatric Patients With Acute Respiratory Failure: A Population Pharmacokinetic-Pharmacogenomic Study.

    abstract:OBJECTIVE:To develop a pharmacokinetic-pharmacogenomic population model of morphine in critically ill children with acute respiratory failure. DESIGN:Prospective pharmacokinetic-pharmacogenomic observational study. SETTING:Thirteen PICUs across the United States. PATIENTS:Pediatric subjects (n = 66) mechanically ven...

    journal_title:Critical care medicine

    pub_type: 杂志文章

    doi:10.1097/CCM.0000000000003741

    authors: Zuppa AF,Benitez GR,Zane NR,Curley MAQ,Bradfield J,Hakonarson H,Gastonguay MS,Moorthy G,Prodell J,Gastonguay MR

    更新日期:2019-06-01 00:00:00

  • The efficacy of loop diuretics in acute renal failure: assessment using Bayesian evidence synthesis techniques.

    abstract:OBJECTIVE:To quantify the therapeutic efficacy of loop diuretics in acute renal failure using Bayesian evidence synthesis, because despite widespread use, the role of diuretics is controversial. DATA SOURCE:Randomized controlled trials or nonrandomized studies, 1966 to January 2007, identified from MEDLINE and EMBASE ...

    journal_title:Critical care medicine

    pub_type: 杂志文章,评审

    doi:10.1097/01.ccm.0000284503.88148.6f

    authors: Sampath S,Moran JL,Graham PL,Rockliff S,Bersten AD,Abrams KR

    更新日期:2007-11-01 00:00:00

  • Clinical Outcomes and Mortality Impact of Hyperbaric Oxygen Therapy in Patients With Carbon Monoxide Poisoning.

    abstract:OBJECTIVES:Carbon monoxide poisoning affects 50,000 per year in the United States alone. Mortality is approximately 3%, and up to 40% of survivors suffer from permanent neurocognitive and affective deficits. Hyperbaric oxygen therapy has shown benefit on reducing the long-term neurologic sequelae of carbon monoxide poi...

    journal_title:Critical care medicine

    pub_type: 杂志文章

    doi:10.1097/CCM.0000000000003135

    authors: Rose JJ,Nouraie M,Gauthier MC,Pizon AF,Saul MI,Donahoe MP,Gladwin MT

    更新日期:2018-07-01 00:00:00

  • Massive hemoptysis from iatrogenic balloon catheter rupture of pulmonary artery: successful early management by balloon tamponade.

    abstract::Cessation of massive hemoptysis after iatrogenic balloon catheter rupture of the pulmonary artery was observed after a 2-ml inflation of the balloon. A wedge angiogram showed a small cavity near the rupture. Secondary lobectomy was performed; however, the patient died 1 month later. Therapeutic approaches of this life...

    journal_title:Critical care medicine

    pub_type: 杂志文章

    doi:10.1097/00003246-198703000-00021

    authors: Thomas R,Siproudhis L,Laurent JF,Bouget J,Bousser J,Camus C,Michelet C

    更新日期:1987-03-01 00:00:00

  • Critical care nursing: workforce issues and potential solutions.

    abstract:OBJECTIVE:To review the history and development of critical care nurses, the supply and demand issues related to critical care nursing, critical care nursing's contribution to patient outcomes, and recommendations to ensure a steady and strong workforce. DATA SOURCE AND SELECTION:Information presented in this article ...

    journal_title:Critical care medicine

    pub_type: 杂志文章,评审

    doi:10.1097/01.CCM.0000203087.42439.53

    authors: Robnett MK

    更新日期:2006-03-01 00:00:00