Abstract:
:We reviewed the charts of 106 patients treated with carbamazepine. Age, sex, race, seizure type, seizure focus, age at onset, duration of epileptic illness, reasons for discontinuing treatment, other medications, and response to treatment of seizures, psychiatric symptoms, and behavioral symptoms were recorded. Statistical analysis was done to determine clinical factors influencing response to carbamazepine. Increasing duration of epileptic illness leads to a decreased response to carbamazepine, which controls both seizure and behavioral symptoms effectively; concurrent medication decreases behavioral symptom control without affecting the control of the seizures. We found a strongly negative correlation between duration of seizures and improvement of psychiatric symptoms with carbamazepine therapy. We provide a clinical profile of the carbamazepine responder to guide clinicians in their use of this drug.
journal_name
South Med Jjournal_title
Southern medical journalauthors
Burns RL,Jenkins PL,Vallini ADdoi
10.1097/00007611-199301000-00005subject
Has Abstractpub_date
1993-01-01 00:00:00pages
23-6issue
1eissn
0038-4348issn
1541-8243journal_volume
86pub_type
杂志文章abstract:INTRODUCTION:Pathologic gambling is a disorder with features that implicate abnormal functioning in brain regions involved in addiction, mood, anxiety, and impulse control disorders. Our goal was to examine brain function with neurocognitive tasks that target these brain regions in patients with pathologic gambling. M...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/01.smj.0000197583.24072.f5
更新日期:2006-01-01 00:00:00
abstract::Ruptured ovarian artery aneurysm is rare. Of the eight cases previously reported, seven were diagnosed postpartum. Our case of a ruptured right ovarian artery aneurysm was associated with massive retroperitoneal bleeding. The probable time of rupture could be traced to the second stage of labor. This case indicates th...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199309000-00023
更新日期:1993-09-01 00:00:00
abstract::Considerable controversy exists with regard to therapeutic efficacy of plasmapheresis in the immune-mediated demyelinating disorders of the peripheral and central nervous system: acute inflammatory polyneuropathy (Guillain-Barré syndrome), chronic inflammatory demyelinating polyneuropathy, and multiple sclerosis. In a...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:10.1097/00007611-198608000-00018
更新日期:1986-08-01 00:00:00
abstract::Seventeen patients with Crohn's disease requiring emergency operative procedures disclosed important factors leading to successful outcome. In seven of the ten patients not known to have Crohn's disease, the history strongly suggested this diagnosis. Two patients died; three others had major complications, including t...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197810000-00010
更新日期:1978-10-01 00:00:00
abstract::A retrospective review of all admissions to the University of Kentucky Medical Center from 1977 to 1987 revealed six persons in whom splenic vein thrombosis could be documented. The patients had either upper gastrointestinal bleeding from gastroesophageal varices or abdominal pain. Pancreatic disease was present in fi...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:10.1097/00007611-199004000-00014
更新日期:1990-04-01 00:00:00
abstract::In a patient with left ventricular failure complicated by shock and impairment of right ventricular function caused by an infarct, right atrial pacing improved cardiac output. We believe right atrial pacing offers an alternative to plasma volume expansion, afterload reducing agents, and inotropic drugs. ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198103000-00030
更新日期:1981-03-01 00:00:00
abstract::Six patients with classical transient ischemic attacks that were not directly related to extracranial carotid disease are presented. These cases were selected to include a variety of pathologic conditions: one case each of brain tumor, arteriovenous malformation, chronic subdural hematoma, cervical spondylosis, and tw...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197606000-00015
更新日期:1976-06-01 00:00:00
abstract::Aspergilloma is a common complication of cystic lung disease; it is widely considered to be a saprophytic colonization and local or disseminated invasion is unusual. We describe a patient with stage IV sarcoidosis and bilateral aspergillomas in whom locally invasive disease led to spinal cord compression. ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198405000-00028
更新日期:1984-05-01 00:00:00
abstract::Rapid loss of erythrocyte galactose-1-phosphate uridyl transferase in hemolysates from an infant 26 days after transfusion led to investigation of the possiblity of an unstable enzyme or other variant of galactosemia. However, the child was found to have the classic type of galactosemia. The seeming transferase instab...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197503000-00010
更新日期:1975-03-01 00:00:00
abstract::A rare case of alveolar rhabdomyosarcoma of the urinary bladder, manifested as a systemic disease in a 51-year-old woman, was diagnosed at necropsy. Diffuse lytic bone lesions and extensive bone marrow involvement with a leukoerythroblastic blood picture led to an initial clinical diagnosis of a hematologic malignancy...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198704000-00031
更新日期:1987-04-01 00:00:00
abstract::We reviewed the operative complications in 333 living related donor nephrectomies done at our institution over the past 12 years. The overall complication rate was 17.1%; only three patients (0.9%) had major complications, and none died. The major complications were a delayed splenectomy because of bleeding, an adrena...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199401000-00013
更新日期:1994-01-01 00:00:00
abstract:OBJECTIVES:Helicobacter pylori is prevalent worldwide, especially in Latin America. Triple and quadruple antibiotic therapies have been relatively effective; however, resistance has emerged in recent years. The treatment success rate of these regimens on the border of the United States and Mexico is unknown. Our study ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.14423/SMJ.0000000000000747
更新日期:2018-01-01 00:00:00
abstract:OBJECTIVES:To determine the prevalence of overweight in a cardiac stress testing population, and the percentage of subjects who indicate a history of overweight. METHODS:A total of 251 consecutive subjects presenting for cardiac stress testing in a 450-bed community hospital from June to September 2010 were asked to c...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/SMJ.0b013e31821e9359
更新日期:2011-07-01 00:00:00
abstract:BACKGROUND:The use of lasers has assumed an increasingly important role in the treatment of a variety of cutaneous lesions over the past few decades. Because of their effectiveness, physicians from a variety of specialties have incorporated lasers into their practices. Unfortunately, widespread availability of lasers a...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:10.1097/00007611-199809000-00002
更新日期:1998-09-01 00:00:00
abstract::Although successful transposition of the ovaries at the time of staging laparotomy for Hodgkin's disease is well documented, little comment has been made on potential complications. This case report of a primary ovarian neoplasm (benign) developing in a transposed ovary serves to alert physicians as to possible ovaria...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198307000-00039
更新日期:1983-07-01 00:00:00
abstract::Phenformin-associated lactic acidosis is an important though unusual cause of acute abdominal pain. Its clinical picture suggests other catastrophic abdominal entities. A representative case is presented. Aids to arriving at this diagnosis are presented and the specific therapy is outlined. The pathophysiology of this...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197803000-00039
更新日期:1978-03-01 00:00:00
abstract::We have reported a case of intraduodenal duct disruption and duodenal hematoma associated with ERCP. The location of the extravasated contrast material created a confusing picture, which preoperatively was thought to be a pseudocyst, but was found at operation to be a duodenal hematoma. In retrospect, the upper gastro...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198711000-00027
更新日期:1987-11-01 00:00:00
abstract::High fever occurred in a 30-year-old woman five weeks after transsphenoidal hypophysectomy for a pituitary adenoma. Extensive investigation failed to reveal any evidence of infection, and the clinical findings suggested the fever to be a manifestation of steroid withdrawal. Either suboptimal dosage of corticosteroid r...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198903000-00027
更新日期:1989-03-01 00:00:00
abstract::Insomnia disorder is present in as much as 30% of the general adult population. Given the significant adverse effects of pharmacotherapy, cognitive behavioral therapy (CBT) has been found to be an effective alternative in individuals with insomnia. CBT for insomnia (CBTi) encompasses sleep hygiene, stimulus control, s...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:10.14423/SMJ.0000000000000769
更新日期:2018-02-01 00:00:00
abstract::Transient synovitis of the hip is an acute and self-limited disease commonly seen in children. It is the most common cause of acute hip pain in children ages 3 to 10. It is not considered a disease of adults. It usually only affects one hip. The child may complain of pain that is much worse with walking and may actual...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/01.smj.0000199746.29009.4c
更新日期:2006-02-01 00:00:00
abstract:OBJECTIVES:To determine why there has been a decrease in the amount of applicants to Florida-based obstetrics and gynecology (OB/GYN) residency programs, and how this has been affected by the current medical liability climate. METHODS:Fourth year Florida medical students were surveyed about their concerns of a career ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/01.smj.0000286757.82926.48
更新日期:2007-11-01 00:00:00
abstract::Bordetella bronchiseptica bacteremia is often associated with various infection in animals. The majority of B bronchiseptica infections reported in humans are cases of pneumonia. Very few cases have been reported in patients with a history of acquired immune deficiency syndrome (AIDS). The patient described herein, wh...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/SMJ.0b013e3181ebcdbc
更新日期:2010-09-01 00:00:00
abstract::We have reported a case of severe erythema multiforme caused by outbreaks of recurrent HSV-2 infection. The EM was debilitating and responded to the treatment of HSV with oral acyclovir. On stopping the oral acyclovir, the HSV and the EM both recurred. We recommend a trial of oral acyclovir in cases of severe EM cause...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198606000-00027
更新日期:1986-06-01 00:00:00
abstract::Renal mechanisms for metabolic acidosis in selective hypoaldosteronism were investigated in a patient with marked renal insufficiency. Studies demonstrated a distal hydrogen ion secretory defect. Control of elevated serum potassium levels did not normalize urinary acid excretion, but systemic acidosis was improved. Mi...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197811000-00023
更新日期:1978-11-01 00:00:00
abstract::Liver cysts are a well-recognized feature of autosomal dominant polycystic kidney disease (ADPKD) and occur in 77% of patients more than 60 years old. Serious sequelae, however, are rare, the two most common complications being pain and cyst infections. Portal hypertension has been reported in ADPKD due to the rare pr...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199906000-00015
更新日期:1999-06-01 00:00:00
abstract::Hearing and/or balance disorders are symptoms that may be associated with tumors of the cerebellopontine angle (CPA). Between March 1988 and May 1995, 22 patients had diagnosis or evaluation of CPA tumors at Cleveland Clinic Florida. The most common presenting signs or symptoms included unilateral low-frequency tinnit...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199705000-00010
更新日期:1997-05-01 00:00:00
abstract::Myxoma is the most common primary tumor of the heart. The typical presentations include a triad of embolic phenomena, intracardiac flow obstruction, and constitutional symptoms. We report a case of cardiac myxoma presenting as prolonged fever. Leukocytosis with a left shift, anemia, and elevated C-reactive protein wer...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/SMJ.0b013e3182142bbd
更新日期:2011-05-01 00:00:00
abstract:BACKGROUND:Despite an effective tetanus vaccine, tetanus continues to claim lives worldwide. The very young and the elderly are at highest risk for the disease. Farmers are at high risk for injury, the leading factor associated with tetanus. METHODS:As part of a larger study of older members of farm households in the ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/SMJ.0b013e31818f6544
更新日期:2009-03-01 00:00:00
abstract::We recently managed a patient with diabetic ketoacidosis who had an exceptionally high arterial oxygen tension of 144 mm Hg while breathing room air. This was higher than the calculated alveolar oxygen tension and suggested the impossible situation of an uphill diffusion gradient. We were surprised to find this is a r...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197909000-00013
更新日期:1979-09-01 00:00:00
abstract:OBJECTIVES:To evaluate the statewide experience in mode of delivery for pregnancies complicated by stillbirth by annual delivery volume and presence of graduate medical education programs. METHODS:This is a descriptive study of all stillbirths without known congenital anomalies or aneuploidy born in our state from Jul...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.14423/SMJ.0000000000001180
更新日期:2020-12-01 00:00:00