Abstract:
OBJECTIVES:To estimate the prevalence of elevated blood lead levels in children receiving well-care checkups; and to evaluate the effectiveness of certain key risk factors in detecting children at higher risk for elevated blood lead levels. DESIGN:Cross-sectional study. SETTING:Two facilities of the Kaiser Permanente Medical Care Program (KPMCP) health maintenance organization (HMO), northern California region. PATIENTS:Six hundred thirty-six children, aged 12 to 60 months, who were seen at four KPMCP facilities in two subregions for a well-care checkup from September 1991 through August 1992. INTERVENTIONS:Blood samples were collected from each child and analyzed for lead content. Participating parents completed a questionnaire that included questions recommended by the Centers for Disease Control and Prevention (CDC) about the child's and the parents' lead exposure via home, workplace, and hobbies. RESULTS:Ninety-six percent of the children had blood lead levels under 10 micrograms/dL. Blood lead levels declined with increasing age and were higher for black children compared with whites. Age of residential housing, mother's education, and residence in an old house with peeling paint had low sensitivity and positive predictive value for identifying children with blood lead levels over 10 micrograms/dL. CONCLUSION:Universal routine screening for elevated blood lead levels in children in an employed, HMO-insured population is not warranted on grounds of prevalence. Responses to CDC questions do not effectively identify high-risk children in this population.
journal_name
Pediatricsjournal_title
Pediatricsauthors
Haan MN,Gerson M,Zishka BAsubject
Has Abstractpub_date
1996-01-01 00:00:00pages
79-83issue
1eissn
0031-4005issn
1098-4275journal_volume
97pub_type
杂志文章,多中心研究相关文献
PEDIATRICS文献大全abstract::Epigenetics, the study of functionally relevant chemical modifications to DNA that do not involve a change in the DNA nucleotide sequence, is at the interface between research and clinical medicine. Research on epigenetic marks, which regulate gene expression independently of the underlying genetic code, has dramatica...
journal_title:Pediatrics
pub_type: 杂志文章,评审
doi:10.1542/peds.2013-1032F
更新日期:2013-12-01 00:00:00
abstract::Congenital fibrosarcoma (CFS) is a rare fibrous tissue malignancy that usually presents in the first few years of life. It is unique among human sarcomas in that it has an excellent prognosis. We describe a temporal clustering of a number of cases of CFS and investigate the possible associated prenatal risk factors. T...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2011-1307
更新日期:2012-10-01 00:00:00
abstract::To assess the relative competence of pediatricians and general practitioners in managing febrile illnesses in childhood, a prospective study was undertaken of 259 children less than 10 years of age seen consecutively at the emergency room of a children's hospital and a general hospital. Both groups of patients were si...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1982-10-01 00:00:00
abstract::The school nurse has a crucial role in the provision of school health services. This statement describes the school nurse as a member of the school health services team and its relation to children with special health care needs. Recommendations for the professional preparation and education of school nurses also are ...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.108.5.1231
更新日期:2001-11-01 00:00:00
abstract:UNLABELLED:Because late repair of coarctation of the aorta (COA) is associated with premature cardiovascular disease in adult life, early detection and treatment is important. OBJECTIVES:To determine the timing of referral to see whether early detection of COA has improved in the past decade, to evaluate the pattern o...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1996-09-01 00:00:00
abstract:OBJECTIVE:To investigate the differences in health problems identified and health services received by children newly entering foster care who participated in a comprehensive multidisciplinary program, compared with children newly entering foster care who received customary community-based services. METHODS:Using a 2-...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.106.1.59
更新日期:2000-07-01 00:00:00
abstract:OBJECTIVE:The medical home model with its emphasis on planned care, care coordination, family-centered approaches, and quality provides an attractive concept construct for primary care redesign. Studies of medical home components have shown increased quality and reduced costs, but the medical home model as a whole has ...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2008-2600
更新日期:2009-07-01 00:00:00
abstract::Since 1961 the Committee on Nutrition of the American Academy of Pediatrics has recommended that prophylactic vitamin K be administered parenterally to all newborn infants, although the exact requirement for vitamin K in the newborn infant is unknown. There is little information about the vitamin K1 (phylloquinone, pr...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1988-01-01 00:00:00
abstract::Isolated sulfite oxidase deficiency is a rare but devastating neurologic disease that usually presents in early infancy with seizures and alterations in muscle tone. Only 21 cases have been reported in the literature. We report a case of a newborn infant boy with isolated sulfite oxidase deficiency who presented with ...
journal_title:Pediatrics
pub_type: 杂志文章,评审
doi:10.1542/peds.2004-1897
更新日期:2005-09-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:An increase in the incidence of systemic candidiasis (SC) followed a change in skin care for extremely low birth weight (ELBW) infants in our neonatal intensive care unit (NICU). We sought to determine whether the use of topical petrolatum ointment (TPO) for skin care of ELBW infants was associ...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.105.5.1041
更新日期:2000-05-01 00:00:00
abstract::Routine use of the 7-valent pneumococcal conjugate vaccine (PCV7), available since 2000, has resulted in a dramatic reduction in the incidence of invasive pneumococcal disease (IPD) attributable to serotypes of Streptococcus pneumoniae contained in the vaccine. However, IPD caused by nonvaccine pneumococcal serotypes ...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2010-1280
更新日期:2010-07-01 00:00:00
abstract:OBJECTIVE:The current recommendation for choosing an appropriate size cuff for measuring blood pressure (BP) is a bladder width to equal 40% of the upper arm circumference (UAC). However, most physicians use the older two-thirds or three-fourths upper arm length (UAL) recommendations to choose a cuff. The aim of this s...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.110.5.920
更新日期:2002-11-01 00:00:00
abstract::Kawasaki disease is a childhood vasculitis of medium-sized vessels, affecting the coronary arteries in particular. We have treated a therapy-resistant child who met all diagnostic criteria for Kawasaki disease. After the boy was given intravenous immunoglobulins and salicylates, as well as several courses of pulsed me...
journal_title:Pediatrics
pub_type: 杂志文章,评审
doi:10.1542/peds.112.4.986
更新日期:2003-10-01 00:00:00
abstract::An 11-year-old boy had clinical signs of an acute inferior wall myocardial infarction. On echocardiography, a left atrial myxoma was demonstrated. Coronary artery embolization from myxoma was confirmed by selective coronary arteriography. The tumor was removed 12 days after acute coronary embolization. The clinical va...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1979-05-01 00:00:00
abstract::The infant rumination syndrome has not been previously reported in a neonatal intensive care setting. We recently managed three infants in our newborn intensive care unit who developed rumination following chronic courses in the unit. The events leading to this condition in each infant are described, as well as the su...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1980-10-01 00:00:00
abstract:OBJECTIVE:To test in the primary care setting the short- and long-term efficacy of a behavioral intervention that simultaneously targeted an overweight child and parent versus an information control (IC) targeting weight control only in the child. METHODS:Two- to 5-year-old children who had BMI ≥85th percentile and an...
journal_title:Pediatrics
pub_type: 杂志文章,随机对照试验
doi:10.1542/peds.2013-4084
更新日期:2014-08-01 00:00:00
abstract::Varicella is a nearly ubiquitous acquired childhood disease. Infectious complications of varicella can be life- or limb-threatening. These complications appear 3 to 4 days after the appearance of varicella exanthem and are heralded by fever, pain, and erythema of the overlying skin. Airway complications of varicella a...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.105.1.e13
更新日期:2000-01-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Diagnostic imaging is often used in the evaluation of children with possible appendicitis. The utility of imaging may vary according to a patient's age and gender. The objectives of this study were (1) to examine the use of computed tomography (CT) and ultrasound for age and gender subgroups o...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2011-3375
更新日期:2012-05-01 00:00:00
abstract::Adverse reactions and antibody response to pertussis toxin, ie, antitoxin, after a booster injection of an acellular pertussis vaccine were studied in 2-year-old children. A majority (212/241) of the children had previously been immunized with either two or three doses of the acellular vaccine at the ages of 6, 7, and...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1989-07-01 00:00:00
abstract::The recognition of fabricated illness (FI) in a child represents a diagnostic challenge. The suspicion of FI often arises from the discrepancy between laboratory tests and clinical history. For instance, (unnecessary) insulin injections by caregivers has been widely described as a common cause of factitious hypoglycem...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2014-4165
更新日期:2015-11-01 00:00:00
abstract::The accuracy of signs and symptoms as predictors of the presence and severity of esophageal injury was evaluated in 378 children admitted to three pediatric hospitals between 1970 and 1980. The signs and symptoms analyzed included nausea, vomiting, dysphagia, refusal to drink, abdominal pain, increased salivation, oro...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1983-05-01 00:00:00
abstract::Mortality and incidence, complexity, and severity of early childhood neurodevelopmental disability are reported for two cohorts of preterm infants of 500 through 1250 g birth weight. Comparing 1978-1979 (cohort 1) and 1988-1989 (cohort 2), 1-year survival improved from 82 (36%) of 226 to 197 (67%) of 291. Cohort 1 sur...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1992-11-01 00:00:00
abstract::Critical to providing cancer therapy to children in rural areas is finding dependable sources of therapy near the patients' homes. In this study, comparison was made of 668 visits by 24 patients to nearby private practitioners, who carried out 70% of the therapy, with 712 visits by 22 other patients for whom all care ...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1980-12-01 00:00:00
abstract::Clarity of speech normally improves throughout the first few years of life, with acquisition of complete intelligibility by 4 years of age. Delayed emergence of intelligibility, or frankly unintelligible speech, often signify the presence of a major disturbance of language, overall cognitive development, or hearing. N...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1988-09-01 00:00:00
abstract:OBJECTIVE:To describe the epidemiologic, clinical, neuroimaging, and laboratory features; treatment; and outcome in a cohort of children with acute disseminated encephalomyelitis (ADEM). METHODS:A 6-year retrospective chart review of children with the diagnosis of ADEM was conducted. RESULTS:Eighteen cases were ident...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.110.2.e21
更新日期:2002-08-01 00:00:00
abstract:BACKGROUND:The Parent Report of Children's Abilities-Revised (PARCA-R) is a questionnaire for assessing cognitive and language development in very preterm infants. Given the increased risk of developmental delay in infants born late and moderately preterm (LMPT; 32-36 weeks), this study aimed to validate this questionn...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2014-0266
更新日期:2014-07-01 00:00:00
abstract::Male circumcision is a common procedure, generally performed during the newborn period in the United States. In 2007, the American Academy of Pediatrics (AAP) formed a multidisciplinary task force of AAP members and other stakeholders to evaluate the recent evidence on male circumcision and update the Academy's 1999 r...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2012-1989
更新日期:2012-09-01 00:00:00
abstract:OBJECTIVES:Multisystem inflammatory syndrome in children (MIS-C) has spread through the pediatric population during the coronavirus disease 2019 pandemic. Our objective for the study was to report the prevalence of conduction anomalies in MIS-C and identify predictive factors for the conduction abnormalities. METHODS:...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2020-009738
更新日期:2020-12-01 00:00:00
abstract:BACKGROUND:Orphan drug development is crucial for children, who are disproportionately affected by rare diseases. Data are lacking on the number, nature, and benefit of recently approved pediatric orphan indications. METHODS:We classified the 402 orphan indications the US Food and Drug Administration approved between ...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2019-3128
更新日期:2020-04-01 00:00:00
abstract:CONTEXT:Recombinant human erythropoietin (rhEPO) is a promising pharmacological agent for neuroprotection in neonates. OBJECTIVE:To investigate whether prophylactic rhEPO administration in very preterm infants improves neurodevelopmental outcomes in a meta-analysis of randomized controlled trials (RCTs). DATA SOURCES...
journal_title:Pediatrics
pub_type: 杂志文章,meta分析,评审
doi:10.1542/peds.2016-4317
更新日期:2017-05-01 00:00:00