Abstract:
:Drug stability studies are expensive and time consuming. Multiple batches are studied to ensure that a product will consistently remain within specifications for its entire expiration dating period. Some of these studies involve the same drug products in similar packages or in multiple strengths. Application of sound statistical design principles can reduce the amount of testing required. We extend the principles stated in the Food & Drug Administration's 1987 publication Guideline for Submitting Documentation for the Stability of Human Drugs and Biologics to setting expiration dating periods for more complex situations.
journal_name
J Pharm Scijournal_title
Journal of pharmaceutical sciencesauthors
Fairweather WR,Lin TY,Kelly Rdoi
10.1002/jps.2600841112subject
Has Abstractpub_date
1995-11-01 00:00:00pages
1322-6issue
11eissn
0022-3549issn
1520-6017pii
S0022-3549(15)49929-0journal_volume
84pub_type
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journal_title:Journal of pharmaceutical sciences
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journal_title:Journal of pharmaceutical sciences
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journal_title:Journal of pharmaceutical sciences
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