Abstract:
:We have investigated the effects of peripherally administered pyruvate and lactate on the intake of high fat (HF) and low fat (LF) diets by a strain of rat either sensitive (Osborne-Mendel, OM) or resistant (SSB/Pl) to high fat-induced obesity. Both pyruvate and lactate inhibited the intake of HF and LF diets by OM rats and these effects were blocked by selective hepatic vagotomy. In contrast, in S5B/Pl rats fed an LF diet the responses to pyruvate and lactate were attenuated and were absent in S5B/Pl rats fed the HF diet. These data suggest that OM and S5B/Pl rats differ either in their metabolism of pyruvate and lactate or in their responses to these metabolites.
journal_name
Physiol Behavjournal_title
Physiology & behaviorauthors
Nagase H,Bray GA,York DAdoi
10.1016/0031-9384(95)02109-4subject
Has Abstractpub_date
1996-03-01 00:00:00pages
555-60issue
3eissn
0031-9384issn
1873-507Xpii
0031-9384(95)02109-4journal_volume
59pub_type
杂志文章abstract::The objective of the study was to confirm the satiety/energy intake effect of a novel fat emulsion (Olibra) versus placebo in the short term. A randomized, double-blind, placebo-controlled, crossover design was used. 41 subjects participated in the study (n=21: junior-normal weight: age 23.7+/-2.8 years; BMI: 22.0+/-1...
journal_title:Physiology & behavior
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/j.physbeh.2008.05.006
更新日期:2008-09-03 00:00:00
abstract::Restoration of memory by pretest reminder treatments following ECS-induced amnesia in principle could be mediated by nonassociative arousal and/or reactivation of information by the reminder stimuli. In the present research, arousal value of the reminder treatment was largely a function of the novelty of the context i...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(85)90333-6
更新日期:1985-08-01 00:00:00
abstract::Fowls were deprived of water for 2 or 6 hr, and then given graded intravenous (IV) injections of water or isotonic saline. With both levels of deprivation, water preloads caused dose-dependent reductions in water intake which matched closely the volumes of preload given, whereas isotonic saline preloads had no effect ...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(88)90114-x
更新日期:1988-01-01 00:00:00
abstract::The vigilance reaction is characterized by a large bradycardia, a pressor response, and inspiratory apnea in anesthetized rabbits and the inhibition of movement in conscious rabbits. This affective response pattern can be elicited by electrical stimulation of the dorsolateral hypothalamus (the hypothalamic vigilance a...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/s0031-9384(97)00004-8
更新日期:1997-09-01 00:00:00
abstract::Studies examined the contribution of textural factors to the ability of rats to sense starch. If rats sense the abrasive effects of starch suspensions, conditioned aversions to starch should generalize to substances having a similar texture. Two substances having a texture similar to that of starch were examined, poly...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(93)90220-a
更新日期:1993-02-01 00:00:00
abstract::Multiple unit activity (MUA) was recorded from the ventral tegmental area (VTA) and mesencephalic locomotor region (MLR) during copulatory behavior of freely moving male rats. Simultaneous accelerometric recordings of the copulatory pelvic thrusting performed by the male rat were taken to precisely correlate in time t...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/s0031-9384(96)00367-8
更新日期:1997-02-01 00:00:00
abstract::The changes in the acquisition of conditioned avoidance responses (CARs) and the performance of some spontaneous behaviors were examined across the estrous cycle of female rats. CARs were facilitated during diestrus, impaired at proestrus and practically abolished at estrus and metestrus. Motor activity and head shaki...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(89)90010-3
更新日期:1989-09-01 00:00:00
abstract::There is considerable evidence suggesting that endogenous opioid peptides (EOP) might play a role in the defensive response to stressful stimuli. The stress associated with receipt of aggression from a female conspecific and physical restraint for collection of serial blood samples (at 10-min intervals) resulted in a ...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(89)90241-2
更新日期:1989-05-01 00:00:00
abstract::To test the hypothesis that testosterone (T) sexually differentiates gonadotropin secretion and sexual behavior by inducing synthesis of messenger RNA (mRNA), newborn female rats received intrahypothalamic infusions of saline or cordycepin, an adenosine analogue that preferentially inhibits synthesis of polyadenylated...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(87)90264-2
更新日期:1987-01-01 00:00:00
abstract::There is increasing evidence, both electrophysiological and behavioral, that bitter and sweet stimuli drive parallel pathways in the gustatory brainstem. Here we report two lines of investigation that suggest significant interactions among these parallel systems. First, responses recorded from single cells in the hams...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(94)90365-4
更新日期:1994-12-01 00:00:00
abstract::By using the two-bottle, self-selection method it was found that an excess of thyroid hormone administration to rats increased water and sodium intake. Thyroidectomy changed the initial preference from water to sodium chloride. Oral treatment of the thyroidectomized rats with thyroid hormones brought salt ingestion ba...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(88)90231-4
更新日期:1988-01-01 00:00:00
abstract::The palatability of a diet is an important determinant of energy intake. Due to a high palatability, a relatively high energy density, and a weak effect on satiation, the consumption of high-fat foods induces passive overfeeding. It is well known that a high-fat diet often leads to a loss of portion control of tasty f...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/j.physbeh.2005.12.014
更新日期:2006-08-30 00:00:00
abstract::Intraperitoneal injections of the opiate antagonist naloxone decreased food intake in both vagotomized and sham-vagotomized rats. Consumption of liquid and solid sucrose, which were used in order to equate baseline intake, was equally suppressed in both groups under food-deprivation and appetitively-motivated conditio...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(82)90345-6
更新日期:1982-11-01 00:00:00
abstract::Appetite and eating are not only controlled by energy needs, but also by extrinsic factors that are not directly related to energy balance. Environmental signals that acquire motivational properties through associative learning-learned cues-can override homeostatic signals and stimulate eating in sated states, or inhi...
journal_title:Physiology & behavior
pub_type: 杂志文章,评审
doi:10.1016/j.physbeh.2011.04.059
更新日期:2011-09-26 00:00:00
abstract::The EEGs of 18 adult male Wistar rats were recorded during a baseline session lasting 7 h (day 1). The following day, rats were trained for a 2-way active avoidance task in an automated shuttle-box. A retention test was scheduled on the third day. On the basis of the number of avoidances scored during the training and...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/s0031-9384(96)00302-2
更新日期:1996-12-01 00:00:00
abstract::The present experiment compared the strengths of taste aversion learning in rats induced by forced swimming in a water pool (5, 15, 30, or 60 min), voluntary running in an activity wheel (15, 30, 60, or 120 min), forced running in a motorized wheel (60 min at the speed of 8 m/min), optional running in the apparatus co...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/j.physbeh.2006.04.013
更新日期:2006-07-30 00:00:00
abstract::We investigated the acute effects of aerobic exercise with blood flow restriction (BFR) on mood state in American football athletes. Twenty-two male American football athletes were randomly assigned to three experimental conditions: 1) aerobic exercise (AE: 40% VO2max), 2) aerobic exercise with BRF (AE + BFR: 40% VO2 ...
journal_title:Physiology & behavior
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.physbeh.2019.112677
更新日期:2019-11-01 00:00:00
abstract::This study shows that the bacterial flora of the rat's vagina plays a role in the determination of female sexual attractivity. In the experiment described, the change in attractivity of a female rat was monitored during the estrous cycle by using a residential plus-maze. The time that male rats spent in the vicinity o...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(88)90359-9
更新日期:1988-01-01 00:00:00
abstract::Single and multiple unit activity was recorded from the amygdaloid nuclei in awake unanesthestized rabbits during classical conditioning of the nictitating membrane (NM) response. Over half o the unit recordings from the amygdaloid complex demonstrated changes in firing rate following the presentation of the tone cond...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(84)90306-8
更新日期:1984-04-01 00:00:00
abstract::The purpose of the review is to highlight the influences of ambient temperature (T(a)) and caloric restriction (CR) on metabolism, cardiovascular function and behavior in mice. Standard vivarium ambient temperatures (T(a)?23 degrees C) are a mild cold stress for mice requiring elevated metabolic rate and food intake. ...
journal_title:Physiology & behavior
pub_type: 杂志文章,评审
doi:10.1016/j.physbeh.2004.04.025
更新日期:2004-07-01 00:00:00
abstract::In order to study the perception of intracranial reward in the rat, a rewarding hypothalamic brain stimulation served as conditioned stimulus (CS) in an avoidance paradigm. The rate of self-stimulations behavior was used to estimate the strength of intracranial reward and reinforcement. Tests of stimulus generalizatio...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(82)90139-1
更新日期:1982-03-01 00:00:00
abstract::Individuals who are sensitive to the bitter compounds phenylthiocarbamide (PTC) and 6-n-propylthiouracil (PROP) are also more sensitive to selected bitter and sweet substances, to sharp-tasting foods, and to the trigeminal irritant capsaicin. PTC/PROP tasters have a greater density of fungiform taste papillae and it i...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/s0031-9384(96)00608-7
更新日期:1997-06-01 00:00:00
abstract::Hypohydration is generally considered to have a negative effect on cognitive function, despite several studies reporting comparable findings between hydration states. Recommendations to avoid moderate dehydration (≥ 2% loss in body mass) are commonly made to athletes, on the provision that this deficit may impair opti...
journal_title:Physiology & behavior
pub_type: 杂志文章,meta分析
doi:10.1016/j.physbeh.2019.03.008
更新日期:2019-05-15 00:00:00
abstract::For this series of experiments, we wanted to investigate issues related to stress and learning. First, we wanted to determine if unpredictable stress might foster generalized fear responses more than predictable stress. Second, we wanted to evaluate how repeated stress might influence a rat's ability to learn what con...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/j.physbeh.2019.05.017
更新日期:2019-09-01 00:00:00
abstract::Gold thioglucose (GTG) has been known to be an obesity causing agent for over 40 years. GTG works by affecting dendrites in the mouse ventromedial hypothalamus (VMH) producing a permanent VMH lesion and subsequent hyperphagia and obesity. We have investigated the effect of beta-thioglucose (BTG), a glucose antimetabol...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(89)90005-x
更新日期:1989-09-01 00:00:00
abstract::Long-Evans hooded rats were tested for emotionality and observed by pairs in an open field for 6 consecutive days. Postoperative observations indicated that both emotionality and social cohesiveness were dramatically altered by ventromedial and anterolateral hypothalamic lesions. Tegmental, interpeduncular and habenul...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(75)90093-1
更新日期:1975-09-01 00:00:00
abstract::Binge eating is characterized by the consumption of a large amount of palatable food in a short period of time and is a core feature of many eating disorders. Patients with eating disorders are also known to display impairments in inhibitory control, cognition and decision-making, which may promote and maintain binge ...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/j.physbeh.2019.03.005
更新日期:2019-07-01 00:00:00
abstract::Ten Hooded Lister rats were divided from weaning into two groups of five. One group was fed exclusively on a liquid diet in the home cage (Complan-fed subjects), the other group was given normal laboratory chow (Chow-fed subjects). At approximately 60 days of age both groups were reduced to 80% of their ad lib body-we...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(84)90062-3
更新日期:1984-01-01 00:00:00
abstract::In cattle, the in vivo effects of centrally administered corticotropin-releasing hormone (CRH) or arginine vasopressin (AVP) from the perspective of stress regulation have not been fully elucidated. We compared behavioral, adrenocorticotropic, and autonomic nervous responses to intracerebroventricularly infused bCRH o...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/j.physbeh.2007.10.014
更新日期:2008-02-27 00:00:00
abstract::The golden spiny mouse Acomys russatus is a rock dwelling rodent which lives in extremely arid and hot habitats. In Israel it is nocturnal except in areas in which it coexists with the common spiny mouse A. cahirinus. In such places it is diurnal. The daily rhythms of body temperature (Tb) and oxygen consumption (VO2)...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(95)00126-4
更新日期:1995-10-01 00:00:00