Fasting increases aggression and differentially modulates local and systemic steroid levels in male zebra finches.

abstract：:In seasonally breeding species, an animal's photoperiodic history (the daylength or photoperiod previously experienced) influences the reproductive response to new photoperiods. However, this has only been examined over a relatively narrow range of photoperiods. We assessed whether Djungarian hamsters (Phodopus sungor...

journal_title：Endocrinology

authors： Rivkees SA,Hall DA,Weaver DR,Reppert SM

更新日期：1988-06-01 00:00:00

abstract：:Adult rats which have received monosodium-L-glutamate (MSG, 4 mg/g BW) on alternate days for the first 10 days of life manifest central nervous system lesions largely restricted to the retina and the arcuate nucleus of the hypothalamus in which nearly 90% of the perikarya are destroyed, leaving axons in passage intact...

journal_title：Endocrinology

authors： Greeley GH Jr,Nicholson GF,Nemeroff CB,Youngblood WW,Kizer JS

更新日期：1978-07-01 00:00:00

abstract：:The expression of the proopiomelanocortin (POMC) gene by normal lung and thyroid was examined by measurement of the content of ACTH, beta-lipotropin (beta LPH), and beta-endorphin (beta EP) in porcine lung and thyroid tissue. Acid extracts of normal porcine lung and thyroid tissue each contained appreciable amounts of...

journal_title：Endocrinology

authors： Clements JA,Funder JW,Tracy K,Morgan FJ,Campbell DJ,Lewis P,Hearn MT

更新日期：1982-12-01 00:00:00

abstract：:Stimulators of bone resorption, such as PTH, 1,25-dihydroxycholecalciferol [1,25-(OH)2D3], or prostaglandin E2 (PGE2), do not cause calcium release from cultured calvaria of the genetically determined osteopetrotic microphthalmic (mi/ mi) mouse, due to a defect in the function of osteoclasts. To investigate the capaci...

journal_title：Endocrinology

authors： Jilka RL,Cohn DV

更新日期：1983-03-01 00:00:00

abstract：:The extent thyroid hormone receptors (TRs) bind to AGGTCA-related motifs as monomers and/or homodimers, and as heterodimers with retinoid X receptors (RXRs) depends on the number, spacing, and orientation of these half-sites. Here we show that recombinant RXR alpha affects TR binding to DNA in diverse ways; it enhance...

journal_title：Endocrinology

authors： Ribeiro RC,Apriletti JW,Yen PM,Chin WW,Baxter JD

更新日期：1994-11-01 00:00:00

abstract：:The monocarboxylate transporter Mct10 (Slc16a10; T-type amino acid transporter) facilitates the cellular transport of thyroid hormone (TH) and shows an overlapping expression with the well-established TH transporter Mct8. Because Mct8 deficiency is associated with distinct tissue-specific alterations in TH transport a...

journal_title：Endocrinology

authors： Müller J,Mayerl S,Visser TJ,Darras VM,Boelen A,Frappart L,Mariotta L,Verrey F,Heuer H

更新日期：2014-01-01 00:00:00

abstract：:The aldo-keto reductase 1B7 (AKR1B7) encodes an aldose-reductase that has been reported as a detoxification enzyme until now. We have demonstrated that AKR1B7 is differently expressed in various mouse white adipose tissues depending on their location. Its expression is associated with a higher ratio of preadipocytes v...

journal_title：Endocrinology

authors： Tirard J,Gout J,Lefrançois-Martinez AM,Martinez A,Begeot M,Naville D

更新日期：2007-05-01 00:00:00

abstract：:Tuberoinfundibular peptide of 39 residues (TIP39) and the PTH-2 receptor (PTH2R) constitute a peptide-receptor neuromodulator system. Based on the abundance of TIP39 fibers and axonal terminals as well as PTH2R-containing neurons and their processes in the hypothalamic para- and periventricular and arcuate nuclei TIP3...

journal_title：Endocrinology

authors： Cservenák M,Bodnár I,Usdin TB,Palkovits M,Nagy GM,Dobolyi A

更新日期：2010-12-01 00:00:00

abstract：:Nonsteroidal anti-inflammatory drugs (NSAIDs) play potential roles in chemoprevention of colon cancer and others by inhibiting prostaglandin synthesis. In this report, we used LNCaP cells, an androgen-responsive human prostate carcinoma cell line, to study the effects of two NSAIDs, flufenamic acid (FA) and piroxicam ...

journal_title：Endocrinology

authors： Zhu W,Smith A,Young CY

更新日期：1999-11-01 00:00:00

abstract：:Apolipoprotein A-IV (apo A-IV) is a satiety factor involved in the control of food intake and body weight. Our previous studies demonstrated that apo A-IV is present in areas of the hypothalamus where leptin acts to influence energy homeostasis. In the present studies, we found that leptin-deficient obese (ob/ob) mice...

journal_title：Endocrinology

authors： Shen L,Tso P,Woods SC,Sakai RR,Davidson WS,Liu M

更新日期：2007-06-01 00:00:00

abstract：:1Alpha,25-dihydroxyvitamin D3 (1,25-(OH)2D3) is a potent mediator of differentiation and maintenance of specific functions of osteoblasts. To detect novel targets for 1,25-(OH)2D3 action, we applied differential display PCR to human fetal osteoblast-like cells and identified the human analog of murine cystein rich pro...

journal_title：Endocrinology

authors： Schütze N,Lechner A,Groll C,Siggelkow H,Hüfner M,Köhrle J,Jakob F

更新日期：1998-04-01 00:00:00

abstract：:5-Hydroxytryptamine (5-HT) is synthesized and secreted by thyroid parafollicular (PF) cells. As all PF granules contain 5-HT, it is released whenever PF cells secrete. Because 5-HT stimulates follicular (F) cells and can modulate their response to TSH, 5-HT has been proposed to be a paracrine PF to F cell transmitter....

journal_title：Endocrinology

authors： Tamir H,Hsiung SC,Liu KP,Blakely RD,Russo AF,Clark MS,Nunez EA,Gershon MD

更新日期：1996-10-01 00:00:00

abstract：:We have investigated the ability of fetal rat skin to heal an excisional wound in vitro. Skin from the backs of E17-E19 rats was wounded using a 1-mm diameter cutting needle and suspended in culture on a 6-pin cradle for 72 h. Neither contraction nor epithelial closure was observed within wounds created in skin from E...

journal_title：Endocrinology

authors： Belford DA

更新日期：1997-09-01 00:00:00

abstract：:In the present study we have examined the effects of FSH, forskolin, and (Bu)2cAMP on messenger RNA (mRNA) levels for all known subunits of cAMP-dependent protein kinase in rat Sertoli cells, using newly developed complementary DNA (cDNA) probes. mRNAs for the three regulatory subunits [RI alpha, RII51, (RII beta), an...

journal_title：Endocrinology

authors： Oyen O,Sandberg M,Eskild W,Levy FO,Knutsen G,Beebe S,Hansson V,Jahnsen T

更新日期：1988-06-01 00:00:00

abstract：:Gonadotropin (GTH)-inhibitory hormone (GnIH) is a novel hypothalamic neuropeptide that inhibits GTH secretion in mammals and birds by acting on gonadotropes and GnRH neurons within the hypothalamic-pituitary-gonadal axis. GnIH and its orthologs that have an LPXRFamide (X = L or Q) motif at the C terminus (LPXRFamide p...

journal_title：Endocrinology

authors： Osugi T,Daukss D,Gazda K,Ubuka T,Kosugi T,Nozaki M,Sower SA,Tsutsui K

更新日期：2012-05-01 00:00:00

abstract：:Immunoaffinity adsorption techniques, utilizing specific antisera for hCG and its subunits bound to Sepharose 4B, have been employed to separate hCG alpha beta dimer and free subunits of hCG. As previously reported by this and a number of other laboratories, trophoblast cells (in vivo and in vitro) produce free alpha ...

journal_title：Endocrinology

authors： Cole LA,Hartle RJ,Laferla JJ,Ruddon RW

更新日期：1983-09-01 00:00:00

abstract：:Androgens are required for the development and function of the prostate. In a normal human prostate, androgens control the synthesis of proteins such as prostate-specific antigen and human glandular kallikrein. The prostate secretes these proteins as well as a number of other compounds to form the prostatic fluid. Usi...

journal_title：Endocrinology

authors： Prescott JL,Tindall DJ

更新日期：1998-04-01 00:00:00

abstract：:Limited proteolysis in vivo of insulin-like growth factor-binding protein-3 (IGFBP-3) by as yet unidentified serine proteases plays a key role in controlling the bioavailability of IGFBP-3-associated insulin-like growth factors (IGFs). Both the IGF system and the system of plasminogen activators (PAs) and their inhibi...

journal_title：Endocrinology

authors： Lalou C,Silve C,Rosato R,Segovia B,Binoux M

更新日期：1994-12-01 00:00:00

abstract：:Intravascular injections of adrenocorticotropic hormone in hypophysectomized rats were approximately 3 times more effective in stimulating increases in plasma corticosteroid concentration when given at the offset rather than the onset of the daily photoperiod (12 h:12 h light-dark cycle). Reversal of the photoperiodic...

journal_title：Endocrinology

authors： Ottenweller JE,Meier AH,Ferrell BR,Horseman ND,Proctor A

更新日期：1978-11-01 00:00:00

abstract：:Hamsters injected sc with 50 mug estradiol cyclopentylpropionate (ECP) at 0900 h on day 1 (metestrus) of the cycle show the normal "postovulatory" vaginal discharge 4 days later but do not resume ovulation until 14--18 days later. After ECP injection ovarian histology reveals that the follicles normally destined to ov...

journal_title：Endocrinology

authors： Greenwald GS

更新日期：1975-10-01 00:00:00

abstract：:Male Sprague-Dawley rats were injected ip with 1 microgram pertussis toxin (PTX)/100 g BW. The rats were killed 24, 48, and 72 h after injection, and their pancreases were removed. At each time point, insulin secretion by isolated islets was measured under basal and glucose-stimulated conditions and in the absence and...

journal_title：Endocrinology

authors： Komatsu M,McDermott AM,Gillison SL,Sharp GW

更新日期：1995-05-01 00:00:00

abstract：:T3 and rT3 production rates in the fetus account for roughly only a third of the total T4 production rate; thus, the fate of the majority of T4 produced in the fetus is unknown (the "T4 disposal gap"). We developed sensitive and specific T4 sulfate (T4S) and T3 sulfate (T3S) RIAs to investigate the roles of these comp...

journal_title：Endocrinology

authors： Wu S,Polk D,Wong S,Reviczky A,Vu R,Fisher DA

更新日期：1992-10-01 00:00:00

abstract：:A protein [steroidogenesis-inducing protein (SIP)] has been isolated from human ovarian follicular fluid and shown previously to stimulate steroidogenesis in Leydig cells, adrenal cells, and early luteal cells. Since proteins and peptides known to regulate steroidogenesis, such as gonadotropins and growth factors, als...

journal_title：Endocrinology

authors： Khan SA,Teerds K,Dorrington J

更新日期：1992-02-01 00:00:00

abstract：:The pregnancy hormone relaxin has recently been shown to be cardio-protective. Despite its well-established antifibrotic actions in the heart, the effects of relaxin on cardiomyocytes (CM) remain to be determined. We investigated effects of isoform 2 of the human relaxin (H2-relaxin) on CM hypertrophy and apoptosis. I...

journal_title：Endocrinology

authors： Moore XL,Tan SL,Lo CY,Fang L,Su YD,Gao XM,Woodcock EA,Summers RJ,Tregear GW,Bathgate RA,Du XJ

更新日期：2007-04-01 00:00:00

abstract：:The structural requirements for the inhibition of net bone collagen synthesis by parathyroid hormone (PTH) in vitro have been examined by study of the effects of selected fragments and analogs of bovine PTH (bPTH) upon the incorporation of [3H]proline into collagenase-digestible and -nondigestible proteins by neonatal...

journal_title：Endocrinology

authors： Bringhurst FR,Potts JT Jr

更新日期：1981-01-01 00:00:00

abstract：:GH-releasing factor (GRF) is a hypothalamic peptide that stimulates the secretion of pituitary GH. The possibility of feedback effects of GRF within the central nervous system was studied in conscious freely moving male rats with indwelling iv and intracerebroventricular (icv) cannulae. Animals were injected icv or iv...

journal_title：Endocrinology

authors： Katakami H,Arimura A,Frohman LA

更新日期：1986-05-01 00:00:00

abstract：:The physiology and regulation of steroid synthesis in the brain have emerged as important for understanding brain function. Neurosteroids, those steroids synthesized de novo in nervous tissue, have been associated with numerous central nervous system functions, including myelination, mental retardation, and epilepsy. ...

journal_title：Endocrinology

authors： Micevych P,Sinchak K

更新日期：2008-06-01 00:00:00

abstract：:This study aimed to delineate the hypothalamic and/or pituitary actions of testosterone and its primary metabolites 5 alpha-dihydrotestosterone and estradiol (E) in adult castrated rams (wethers) during the breeding season. In Exp 1, wethers were treated for a week with twice daily injections (im) of peanut oil, 8, 16...

journal_title：Endocrinology

authors： Tilbrook AJ,de Kretser DM,Cummins JT,Clarke IJ

更新日期：1991-12-01 00:00:00

abstract：:Central administration of melanocortin 3 and 4 receptor (MC3/4-R) agonists increases energy expenditure, with the hypothalamus commonly held as the primary site of action. It is also clear, however, that MC4-R are expressed in caudal brainstem structures of relevance to the control of energy expenditure. Three experim...

journal_title：Endocrinology

authors： Williams DL,Bowers RR,Bartness TJ,Kaplan JM,Grill HJ

更新日期：2003-11-01 00:00:00

abstract：:The direct effects of cortisol and cortisone on insulin and glucagon secretion by the isolated perfused rat pancreas were examined. Cortisone, but not cortisol, in a final concentration of 10(-4) M acutely and strongly inhibited both phases of glucose- and arginine-induced insulin secretion. In repeated pulse administ...

journal_title：Endocrinology

authors： Barseghian G,Levine R,Epps P

更新日期：1982-11-01 00:00:00