Abstract:
:This study compared demineralized-unicortical-ilium-strips (DUIS) and an expanded polytetrafluoroethylene (ePTFE) physical barrier in combination with decalcified freeze-dried bone allograft (DFDBA) for treatment of Class II mandibular furcations. Twenty patients with adult periodontitis and at least 2 furcation invasions participated in this study. Probing depth (PD), clinical attachment level (CAL), and bone fill were measured at 6 and 12 months. Standardized radiographs were analyzed using computer assisted densitometric image analysis (CADIA). Fifteen of 20 patients completed the 12-month evaluation. At 6 months both control and test groups showed significant reductions in PD from baseline (P < 0.01). PD reduction for the ePTFE + DFDBA sites was 2.13 mm +/- 1.25, and the DUIS + DFDBA, 1.77 mm +/- 1.21. CAL at 6 months was sustained to 12 months when the net gains in CAL for ePTFE + DFDBA being 1.30 mm +/- 1.45 (P < 0.01) and for DUIS + DFDBA sites 1.13 mm +/- 1.68 (P < 0.02). The horizontal furcation PD decreased 2.87 mm +/- 1.68 (P < 0.01) in the ePTFE + DFDBA and 1.70 mm +/- 1.69 (P < 0.01) for DUIS + DFDBA sites over 12 months. The evaluation of the hard tissue response at the 12-month re-entry demonstrated a bone fill of 2.37 mm (75%) +/- 2.04 (P < 0.01) with ePTFE + DFDBA and 1.83 mm (79%) +/- 1.57 (P < 0.01) with DUIS + DFDBA. DUIS material and ePTFE showed significant improvements in clinical parameters and neither material proved to be significantly better. However, a larger sample size may have permitted us to demonstrate statistically significant differences between the materials. The positive results from the utilization of DUIS for GTR and the advantage of its bioresorbability warrant further investigation. The study found limitations in the use of CADIA for evaluation of guided tissue regeneration in furcations.
journal_name
J Periodontoljournal_title
Journal of periodontologyauthors
Yamaoka SB,Mellonig JT,Meffert RM,Arnold RM,Nummikoski PV,Mealey BLdoi
10.1902/jop.1996.67.8.803subject
Has Abstractpub_date
1996-08-01 00:00:00pages
803-15issue
8eissn
0022-3492issn
1943-3670journal_volume
67pub_type
杂志文章abstract:BACKGROUND:This study evaluates the effects on clinical and biochemical parameters of Lactobacillus reuteri-containing probiotic supplementation adjunctive to initial periodontal therapy in patients with chronic periodontitis (CP). METHODS:Thirty patients with CP were included and divided into two groups. Every patien...
journal_title:Journal of periodontology
pub_type: 杂志文章,随机对照试验
doi:10.1902/jop.2015.140612
更新日期:2015-06-01 00:00:00
abstract:BACKGROUND:In classic albinism, all parts of the body are normal except for the absence of melanin. It is believed that lack of this pigment in periodontal tissues might influence periodontal disease progression. This study was designed to determine the relationship between periodontal diseases and albinism by comparin...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2007.050322
更新日期:2007-01-01 00:00:00
abstract:BACKGROUND:Collagen membranes cross-linked by glycation (GLYM) for guided bone regeneration (GBR) and guided tissue regeneration (GTR) are used extensively with proven safety and efficacy. Complete GLYM ossification, when placed in contact with bone, was described in a canine jaw model, suggesting that GLYM may serve a...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2008.070421
更新日期:2008-06-01 00:00:00
abstract:BACKGROUND:A 5-year-old Japanese boy presented with persistent gingival inflammation and severe mobility of the right lower primary incisors. Due to severe alveolar bone loss and a deep periodontal pocket (5 mm), the incisors were extracted at the second visit. METHODS:Clinical, radiographic, histological, and microbi...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2003.74.7.1060
更新日期:2003-07-01 00:00:00
abstract:BACKGROUND:Recent research suggests that osteopenia may be a predisposing factor for periodontal tissue destruction. If so, then a relationship should exist between measures of systemic bone mineral density and periodontal tissue destruction. The purpose of the present cross-sectional study was to evaluate the associat...
journal_title:Journal of periodontology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1902/jop.1999.70.9.982
更新日期:1999-09-01 00:00:00
abstract:BACKGROUND:Some studies have advocated marrow penetration in guided bone augmentation (GBA), whereas others have shown that bone can be generated without marrow penetration. This study examined the effect of marrow penetration and the optimal rate of penetration. METHODS:In 10 rabbits, the calvarium was exposed, and c...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2007.070086
更新日期:2007-10-01 00:00:00
abstract:BACKGROUND:Previous studies demonstrated significant variability in the histologic biologic width in periodontal health and mild periodontitis. The purpose of this study was to determine whether the previously established dimensions of the biologic width applied to subjects with severe, generalized, chronic periodontit...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2008.080066
更新日期:2008-10-01 00:00:00
abstract:BACKGROUND:Several anti-inflammatory drugs have been used to reduce pain and discomfort after periodontal surgeries. This study evaluates the efficacy of using etoricoxib and dexamethasone for pain prevention after open-flap debridement surgery. METHODS:For this prospective, double-masked, crossover, placebo-controlle...
journal_title:Journal of periodontology
pub_type: 杂志文章,随机对照试验
doi:10.1902/jop.2010.100059
更新日期:2010-08-01 00:00:00
abstract::The American Academy of Periodontology has developed the following parameter on the treatment of chronic periodontitis with slight to moderate loss of periodontal supporting tissues. Patients should be informed of the disease process, therapeutic alternatives, potential complications, expected results, and their respo...
journal_title:Journal of periodontology
pub_type: 指南,杂志文章,实务指引
doi:10.1902/jop.2000.71.5-S.853
更新日期:2000-05-01 00:00:00
abstract:BACKGROUND:Recent research indicated that periodontal infection may worsen systemic diseases, including pulmonary disease. Respiratory infections, such as pneumonia and the exacerbation of chronic obstructive pulmonary disease, involve the aspiration of bacteria from the oropharynx into the lower respiratory tract. ME...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2011.100582
更新日期:2011-08-01 00:00:00
abstract:BACKGROUND:The biologic safety profile of oral health care products is often assumed on the basis of simplistic test models such as monolayer cell culture systems. We developed and characterized a tissue-engineered human oral mucosal model, which was proven to represent a potentially more informative and more clinicall...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2009.080610
更新日期:2009-05-01 00:00:00
abstract::Periodontal disease is a common infection-induced inflammatory disease among individuals suffering from diabetes mellitus. The purpose of this study was to assess the effects of treatment of periodontal disease on the level of metabolic control of diabetes. A total of 113 Native Americans (81 females and 32 males) suf...
journal_title:Journal of periodontology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1902/jop.1997.68.8.713
更新日期:1997-08-01 00:00:00
abstract:BACKGROUND:Aggressive periodontitis is characterized by rapid destruction of periodontal tissue caused by Aggregatibacter actinomycetemcomitans. Interleukin (IL)-1β is a proinflammatory cytokine, and its production is tightly regulated by inflammasome activation. Xylitol, an anticaries agent, is anti-inflammatory, but ...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2016.150477
更新日期:2016-06-01 00:00:00
abstract:BACKGROUND:This research explored how patients with surgical versus non-surgical periodontal treatment differ in trait anxiety, depression, perceived stress, and well-being on the day of surgery and in their reported pain and use of pain medication 2 and 4 weeks after treatment. In addition, it was investigated how psy...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2006.050302
更新日期:2006-07-01 00:00:00
abstract:BACKGROUND:Oscillating-rotating power toothbrushes have been proven to be clinically efficacious. To the best of the authors' knowledge, a clinical evaluation of the safety of these toothbrushes after surgical root coverage procedures has not been published. The aim of this study is to evaluate the gingival margin (GM)...
journal_title:Journal of periodontology
pub_type: 杂志文章,随机对照试验
doi:10.1902/jop.2016.150528
更新日期:2016-10-01 00:00:00
abstract::This investigation studied the changes in probing depths and subgingival microbial flora of clinically healthy and diseased sites before and after scaling and root planing. Thirty-six sites in 18 individuals were studied in two groups of patients, Group I (9 patients) had received no periodontal surgery, while group I...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1984.55.7.391
更新日期:1984-07-01 00:00:00
abstract::A system of nomenclature for deformities of the alveolar process is presented. Descriptive, familiar topographic terms are used (crater, trench, moat, ramp and plane), and specific criteria are given for each term. Two hundred randomly selected osseous deformities in dry skulls were classified by two examiners at inde...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1984.55.6.336
更新日期:1984-06-01 00:00:00
abstract:BACKGROUND:The most recent classification of periodontal diseases includes a new section on traumatic gingival lesions. Traumatic lesions of the gingiva are thought to be highly prevalent, yet the periodontal literature contains few references on the topic. The purpose of this article is to present a broad spectrum of ...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2004.75.5.762
更新日期:2004-05-01 00:00:00
abstract::HTR polymer was evaluated as a grafting material in periodontal osseous defects in 21 adult patients. Following initial preparation and pre-surgical documentation with standardized measurements, radiographs, and photographs, vertical osseous defects were treated with surgical open flap debridement alone (DEBR) or with...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1990.61.10.633
更新日期:1990-10-01 00:00:00
abstract:BACKGROUND:Recently, a genetic marker (IL-1 genotype) that identifies individuals at higher risk for developing severe periodontal disease was discovered. A subgroup of the population reported on earlier was evaluated to determine if knowledge of the patient's IL-1 genotype would improve accuracy in assignment of progn...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1999.70.1.49
更新日期:1999-01-01 00:00:00
abstract:BACKGROUND:Pentraxins are classic mediators of inflammation and markers of acute-phase reactions. Pentraxin-3 (PTX3) is the first-identified long pentraxin and is believed to be a true independent indicator of disease activity. Although a classic pentraxin, C-reactive protein, and its association with various systemic ...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2010.100526
更新日期:2011-05-01 00:00:00
abstract::Saliva and serum samples were collected from 36 individuals with selective immunoglobulin A deficiency (IgAd) and 23 patients with common variable immunodeficiency (CVI). The oral examination included registration of the teeth, Russell's periodontal index (PI), pocket formation, and salivary flow rate in both unstimul...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1992.63.12.984
更新日期:1992-12-01 00:00:00
abstract:BACKGROUND:This case report describes a 22-year-old female who was referred with a radiolucent lesion between her mandibular right molars. The original radiographic image suggested an odontogenic cyst. METHODS:The surgical enucleation and osteotomy of the residual cavity were performed with a piezoelectric knife. Hist...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2007.060417
更新日期:2007-07-01 00:00:00
abstract::The botryoid odontogenic cyst is considered to be a multiloculated variant of the lateral periodontal cyst. Fewer than 40 of these lesions have been described, many of which have recurred. This paper describes the demographic, clinical, microscopic, and radiographic features of 33 unreported cases from the files of th...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1995.66.12.1069
更新日期:1995-12-01 00:00:00
abstract::von Willebrand's disease (vWD) is one of the most common hereditary hemorrhagic disorders. A mild to moderate deficiency of factor VIII and von Willebrand factor (vWf) often is associated with gingival bleeding. In this case report, the periodontal treatment of a patient with vWD is described. A 45-year-old woman with...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1999.70.5.548
更新日期:1999-05-01 00:00:00
abstract:BACKGROUND:Crohn's disease is a chronic inflammatory bowel disease characterized by uncertainty in etiology and pathogenesis occasionally with manifestations in oral mucous membranes. This report reviews the literature on Crohn's disease and presents a patient with Crohn's disease on continuous anti-inflammatory and im...
journal_title:Journal of periodontology
pub_type: 杂志文章,评审
doi:10.1902/jop.2003.74.4.537
更新日期:2003-04-01 00:00:00
abstract:BACKGROUND:Dendritic cells are characterized by shape, structure, and membrane molecule expression; they contact T lymphocytes to present antigens and stimulate plasma cell differentiation in vitro. Dendritic cells are known to be present in healthy human gingiva and to be altered in HIV-associated periodontitis. Here,...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2002.73.1.45
更新日期:2002-01-01 00:00:00
abstract:BACKGROUND:Dietary calcium has long been a candidate to modulate periodontal disease. Animal as well as human studies of calcium intake, bone mineral density, and tooth loss provide a rationale for hypothesizing that low dietary intake of calcium is a risk factor for periodontal disease. METHODS:We evaluated the role ...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2000.71.7.1057
更新日期:2000-07-01 00:00:00
abstract:BACKGROUND:Sex hormones are linked to inflammation and bone turnover. The goal of this study is to explore the association between sex hormone levels and periodontitis in men using data from the third National Health and Nutrition Examination Survey (NHANES III). METHODS:Data from 755 men (aged ≥ 30 years), including ...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2015.140530
更新日期:2015-10-01 00:00:00
abstract:BACKGROUND:The long-term survival of dental implants depends, in part, on control of bacterial infection in the peri-implant region. Periodontal pathogens colonized implants symptomatic through infection, whereas the microbiota of successful implants was similar to that of periodontal health. This study examined the im...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1999.70.2.131
更新日期:1999-02-01 00:00:00