Congenital diaphragmatic hernia. In utero therapy and ethical considerations.

abstract：:Many aspects of the forward propulsion of enteral nutrients are not fully mature in the preterm and term neonate. Because the regulation of motor activity in the gastrointestinal tract is complex and multifaceted, many levels of regulation of this activity are immature in the preterm infant; however, as neonatologists...

journal_title：Clinics in perinatology

authors： Berseth CL

更新日期：1996-06-01 00:00:00

abstract：:Decades of research have led to the understanding of neonatal pulmonary physiology and have influenced the clinical care that neonatologists provide to the sick newborn. Advances in microprocessor technology have allowed for clinical access of the research-based measurements of neonatal pulmonary functions. These eval...

journal_title：Clinics in perinatology

authors： Bhutani VK,Sivieri EM

更新日期：2001-09-01 00:00:00

abstract：:Current methods of intrapartum surveillance have made little impact on fetal mortality and morbidity while leading to increased caesarean section rates. Near-infrared spectroscopy is a powerful new technique that can continuously measure changes in fetal cerebral oxygenation and hemodynamics during labor. Data are pre...

journal_title：Clinics in perinatology

authors： Peebles DM

更新日期：1997-09-01 00:00:00

abstract：:Preterm births remain a major cause of neonatal morbidity and mortality despite our efforts over the past several decades. Our improved understanding of the complex mechanisms surrounding preterm labor, however, has resulted in the development of numerous biologic and clinical predictors of spontaneous preterm births....

journal_title：Clinics in perinatology

authors： Lu GC,Goldenberg RL

更新日期：2000-06-01 00:00:00

abstract：:The Mothers' Milk Bank (MMB) of San Jose, CA, has provided banked human milk to clinicians and researchers since its founding in 1974. This article briefly acknowledges the many and varied reasons for the use of human milk. Its primary focus however, is to review the protocol followed by the MMB for collection, bankin...

journal_title：Clinics in perinatology

authors： Asquith MT,Pedrotti PW,Stevenson DK,Sunshine P

更新日期：1987-03-01 00:00:00

abstract：:In the past, all women with a family history of breast or ovarian cancer were considered to be at increased risk of cancer themselves. The discovery of BRCA1 and BRCA2 demonstrated that susceptibility to breast and ovarian cancer can be inherited by women as a single-gene autosomal dominant disorder. For such women, e...

journal_title：Clinics in perinatology

authors： Frank TS,Critchfield GC

更新日期：2001-06-01 00:00:00

abstract：:The educational programs that have been developed in newborn special care facilities have two purposes: first, they teach personnel the manual skills that are necessary to manage the sick newborn infant; second, they provide personnel with a better understanding of neonatal pathophysiology so that they can begin to re...

journal_title：Clinics in perinatology

authors： Coen RW

更新日期：1976-09-01 00:00:00

abstract：:Outcomes of neonatal intensive care unit (NICU) graduates have been categorized by rates of neurodevelopmental impairment at 2 years old. Although useful as metrics for research, these early childhood assessments may underestimate or overestimate later functional capabilities. Often overlooked are less severe but more...

journal_title：Clinics in perinatology

authors： Kilbride HW,Aylward GP,Carter B

更新日期：2018-09-01 00:00:00

abstract：:For more than 100 years, three principles have guided the treatment of neonatal asphyxia: maintain body heat, free air passages of obstructions, and stimulate respiration by supplying air to the lungs for oxygenation of the blood. This article addresses the question of which gas, air or 100% oxygen, is best supplied t...

journal_title：Clinics in perinatology

authors： Richmond S,Goldsmith JP

更新日期：2006-03-01 00:00:00

abstract：:Neonatal stress responses have been investigated only in recent years. Term neonates mount substantial hormonal and metabolic responses, which are distinct from those of adult patients. These responses can be altered significantly by the effects of prematurity, the effects of graded surgical stress, and the anesthetic...

journal_title：Clinics in perinatology

authors： Anand KJ

更新日期：1990-03-01 00:00:00

abstract：:Most pharmacokinetic and biologic attributes of digitalis are age dependent. They are determined in great measure by the chemical structure of the specific cardiac glycoside being used. These effects differ in the intact normal circulation and in heart failure because of the altered autonomic nervous system and hormon...

journal_title：Clinics in perinatology

authors： Hastreiter AR,John EG,van der Horst RL

更新日期：1988-09-01 00:00:00

abstract：:The treatment of cocaine abuse among pregnant women involves attention not only to the cocaine use, but also to the pregnancy and constellation of medical and social problems substance-abusing women experience. Writing about the needs of women who enter treatment for drug-dependence treatment, Reed has offered suggest...

journal_title：Clinics in perinatology

authors： Farkas KJ,Parran TV Jr

更新日期：1993-03-01 00:00:00

abstract：:Our experience in the management of 138 infants with various causes of intestinal obstruction has provided us with important principles of diagnosis and treatments that we adhere to in the course of our practice. 1. The overall mortality of neonates suffering from intestinal obstruction should be fewer than 5 per cent...

journal_title：Clinics in perinatology

authors： Reyes HM,Meller JL,Loeff D

更新日期：1989-03-01 00:00:00

abstract：:Necrotizing enterocolitis (NEC) is a multifactorial disorder that primarily affects premature infants. Human milk compared with formula reduces the incidence of NEC. Feeding practices do not increase the incidence of NEC in preterm infants. There is no evidence supporting continuous versus intermittent tube feedings i...

journal_title：Clinics in perinatology

authors： Ramani M,Ambalavanan N

更新日期：2013-03-01 00:00:00

abstract：:The LBW infant with congenital heart defects is likely to be at a higher risk for postoperative death and complications than their normal-sized counterparts because of the effects of prematurity and other organ system dysfunction. Current experience, however, does not suggest that waiting to obtain an arbitrary weight...

journal_title：Clinics in perinatology

authors： Wernovsky G,Rubenstein SD,Spray TL

更新日期：2001-03-01 00:00:00

abstract：:Using the pregnant woman as a means to medicate her fetus represents a new and exciting therapeutic approach in clinical pharmacology. In years to come, we will see an increase in the use of the currently accepted fetal therapies and an increase in the number of therapies available to the caregiver or clinician aimed ...

journal_title：Clinics in perinatology

authors： Simone C,Derewlany LO,Koren G

更新日期：1994-09-01 00:00:00

abstract：:Administrative data research on maternal racial disparities supports 2 broad clinical inferences. First, failure to rescue in terms of both death and severe maternal morbidity likely accounts for a significant proportion of maternal disparities. Second, risk for adverse outcomes by race is generally differential with ...

journal_title：Clinics in perinatology

authors： Friedman A

更新日期：2020-12-01 00:00:00

abstract：:Pulse oximetry, a noninvasive technique of measuring oxygen saturation continuously, is being used increasingly in the intensive care setting. This article provides information regarding physiologic basis and practical aspects of clinical usage of pulse oximetry in the neonate, both in medical and surgical units. ...

journal_title：Clinics in perinatology

authors： Dziedzic K,Vidyasagar D

更新日期：1989-03-01 00:00:00

abstract：:Visual evoked potentials (VEPs) are easily recorded in the neonatal intensive care setting using light-emitting diode goggles as the flash stimulus. They are sensitive measures of CNS integrity and are altered or abolished by hypoxia. Prognosis in newborns with birth asphyxia or hypoxia is difficult to predict; howeve...

journal_title：Clinics in perinatology

authors： Whyte HE

更新日期：1993-06-01 00:00:00

abstract：:Discussed in this article are the effects of pregnancy-induced hypertension on the renin-angiotensin-aldosterone system; the possible role of prostanoids, deoxycorticosterone, and deoxycorticosterone sulfate in blood pressure control; and the effect of pregnancy-induced hypertension upon the endocrinology of the mater...

journal_title：Clinics in perinatology

authors： Carr BR,Gant NF

更新日期：1983-10-01 00:00:00

abstract：:Pharmacotherapy for gastroesophageal reflux (GER) in neonates, aimed at interfering with this physiologic process and potentially reducing the negative sequelae that providers often attribute to GER, consists primarily of drugs that increase the viscosity of feeds, reduce stomach acidity, or improve gut motility. Medi...

journal_title：Clinics in perinatology

authors： Malcolm WF,Cotten CM

更新日期：2012-03-01 00:00:00

abstract：:This article reviews the significance of hypoxic-ischemic encephalopathy and the associated patterns of cerebral injury in the context of the most probable timing of the insult and prognosis. The evolution of the clinical features of significant hypoxic-ischemic encephalopathy, and the diagnostic value of imaging and ...

journal_title：Clinics in perinatology

authors： Hill A,Volpe JJ

更新日期：1989-06-01 00:00:00

abstract：:Liquid breathing has been in medical literature for nearly 80 years and has been proposed as a means of improving gas exchange in critically ill infants since the 1970s. Extensive laboratory experience with perfluorochemical liquid ventilation has lead to clinical trials in infants, children, and adults. This article ...

journal_title：Clinics in perinatology

authors： Greenspan JS,Cleary GM,Wolfson MR

更新日期：1998-03-01 00:00:00

abstract：:When cystic hygroma is detected antenatally, the prognosis is usually poor, and intrauterine or neonatal death are common. This seems especially true for Turner syndrome (the largest etiologic group associated with cystic hygroma) and the lethal multiple pterygium syndromes. However, some fetuses with Turner syndrome,...

journal_title：Clinics in perinatology

authors： Edwards MJ,Graham JM Jr

更新日期：1990-09-01 00:00:00

abstract：:Cesarean delivery as a result of maternal request is increasingly popular, leading to important ethical questions. One of the challenging issues is balancing respect for the autonomy of a pregnant woman with concerns of beneficence and nonmaleficence for her and the fetus. The perceived benefit of cesarean section is ...

journal_title：Clinics in perinatology

authors： Williams HO

更新日期：2008-06-01 00:00:00

abstract：:This article summarizes new information on the natural history of maternal varicella and maternal parvovirus B19. Controversies in the therapy of respiratory syncytial virus are presented. Prophylactic and therapeutic immunotherapy of neonatal enteroviral disease are reviewed. ...

journal_title：Clinics in perinatology

authors： Keyserling HL

更新日期：1997-03-01 00:00:00

abstract：:Prevention of harm from medication errors has become a national priority. Medication errors in the neonatal intensive care unit are common, and most can be avoided. This article reviews the prevalence and types of medication errors affecting the care of the neonate and summarizes approaches that have been used to redu...

journal_title：Clinics in perinatology

authors： Stavroudis TA,Miller MR,Lehmann CU

更新日期：2008-03-01 00:00:00

abstract：:Fetal and neonatal infections can occur at different times during pregnancy, from conception to birth. Infections that take place near the time of conception often destroy the zygote or embryo and only rarely leave definitive evidence. The mother can transmit the infection to her fetus through several routes, but the ...

journal_title：Clinics in perinatology

authors： Zeichner SL,Plotkin SA

更新日期：1988-06-01 00:00:00

abstract：:Numerous articles have chronicled the problems that stem from patients' lack of compliance with health care recommendations, yet there has not been a systematic approach to the development of a strategy for increasing the effectiveness of health education programs. In this article, making use of anticipatory guidance,...

journal_title：Clinics in perinatology

authors： Christophersen ER

更新日期：1985-06-01 00:00:00

abstract：:Although hyperbilirubinemia is extremely common among neonates and is usually mild and transient, it sometimes leads to bilirubin-induced neurologic damage (BIND). The auditory pathway is highly sensitive to the effects of elevated total serum/plasma bilirubin (TB) levels, with damage manifesting clinically as auditor...

journal_title：Clinics in perinatology

authors： Olds C,Oghalai JS

更新日期：2016-06-01 00:00:00