Other viral agents of perinatal importance. Varicella, parvovirus, respiratory syncytial virus, and enterovirus.

abstract：:Decades of research have led to the understanding of neonatal pulmonary physiology and have influenced the clinical care that neonatologists provide to the sick newborn. Advances in microprocessor technology have allowed for clinical access of the research-based measurements of neonatal pulmonary functions. These eval...

journal_title：Clinics in perinatology

authors： Bhutani VK,Sivieri EM

更新日期：2001-09-01 00:00:00

abstract：:MPR and ST are important options for patients who have multifetal pregnancies. Both procedures have been shown to be technically safe and result in acceptable pregnancy loss rates and GAs at delivery. An important caveat is that these findings are observed in centers that have vast experience performing this type of p...

journal_title：Clinics in perinatology

authors： Bush MC,Eddleman KA

更新日期：2003-09-01 00:00:00

abstract：:This article examines the role of biologic and environmental factors in determining the long-term outcomes of extremely low-birth weight infants. Research focusing on follow-up to at least 4 years of age is reviewed. Methodologic issues related to sampling, the use of control groups, and diagnostic criteria are also d...

journal_title：Clinics in perinatology

authors： Lester BM,Miller-Loncar CL

更新日期：2000-06-01 00:00:00

abstract：:In understanding the various electrolyte disorders associated with respiratory failure, one has to appreciate how the otherwise healthy premature infant maintains extracellular fluid homeostasis. The same physiologic processes that regulate body fluids are affected to varying degrees in the infant with respiratory fai...

journal_title：Clinics in perinatology

authors： Brem AS

更新日期：1992-03-01 00:00:00

abstract：:Inherited organic acidemias are a group of metabolic disorders currently being described and investigated as gas-liquid chromatography is applied to unexplained diseases of infancy and childhood. Common clinical presentations include attacks of ketoacidosis, unexplained metabolic acidosis, failure of normal developmen...

journal_title：Clinics in perinatology

authors： Mahoney MJ

更新日期：1976-03-01 00:00:00

abstract：:It is clear that prostaglandins and related compounds are important in the physiology and pathophysiology of the perinatal pulmonary circulation. This article focuses on what is known about prostaglandin-related compounds (PRC) in the pulmonary circulation of the developing and newly born mammal. Also included is a di...

journal_title：Clinics in perinatology

authors： Philips JB 3rd,Lyrene RK

更新日期：1984-10-01 00:00:00

abstract：:The final common pathway to death in all of us is an arrhythmia, yet we still know far too little about the contribution of conduction abnormalities and arrhythmias to the compromised states of the human fetus. At no other time in the human life cycle is the human being at more risk of unexplained and unexpected death...

journal_title：Clinics in perinatology

authors： Strasburger JF,Cheulkar B,Wichman HJ

更新日期：2007-12-01 00:00:00

abstract：:Oxygen therapy is an essential part of neonatal care. Targeting oxygen saturations and preventing hypoxemia and hyperoxemia is difficult, particularly in preterm infants. The mode of oxygen delivery directly affects the stability of oxygen saturations, hypoxemia, and hyperoxemia. This stability has important clinical ...

journal_title：Clinics in perinatology

authors： Travers CP,Carlo WA

更新日期：2019-09-01 00:00:00

abstract：:Immunotherapy was a common method of treating infectious diseases in the preantibiotic era. Serotherapy was a popular approach to serious infections and employed hyperimmune globulins harvested from various large animals. Such antisera needed to be administered early in the course of the disease and unfortunately was ...

journal_title：Clinics in perinatology

authors： Kliegman RM,Clapp DW

更新日期：1991-06-01 00:00:00

abstract：:A scheme of regionalization is proposed in which a regional perinatal system within a defined geographic area permits access of the high risk mother-fetus and infant to the appropriate level of technology for improved perinatal outcome. ...

journal_title：Clinics in perinatology

authors： Merkatz IR,Johnson KG

更新日期：1976-09-01 00:00:00

abstract：:The signs and symptoms associated with necrotizing enterocolitis (NEC) and the common scenarios in which NEC is observed are described to help physicians appreciate the breadth of this illness and to aid in the identification and diagnosis of those affected. An outline for medical management of infants with NEC is pre...

journal_title：Clinics in perinatology

authors： Kanto WP Jr,Hunter JE,Stoll BJ

更新日期：1994-06-01 00:00:00

abstract：:Continuous positive airway pressure (CPAP) systems can be broadly grouped into continuous flow or variable flow devices. Bubble CPAP (bCPAP) is a continuous flow device and has physiologic properties that could facilitate gas exchange. Its efficacy has been reported to be similar to variable flow CPAP systems when use...

journal_title：Clinics in perinatology

authors： Gupta S,Donn SM

更新日期：2016-12-01 00:00:00

abstract：:Using the pregnant woman as a means to medicate her fetus represents a new and exciting therapeutic approach in clinical pharmacology. In years to come, we will see an increase in the use of the currently accepted fetal therapies and an increase in the number of therapies available to the caregiver or clinician aimed ...

journal_title：Clinics in perinatology

authors： Simone C,Derewlany LO,Koren G

更新日期：1994-09-01 00:00:00

abstract：:Advances in fetal echocardiography are providing highly accurate diagnoses of congenital heart disease prior to delivery, making it possible to plan the delivery-room management of these newborns. Knowledge of the expected transitional circulation occurring with birth and the pathophysiologic implications of congenita...

journal_title：Clinics in perinatology

authors： Johnson BA,Ades A

更新日期：2005-12-01 00:00:00

abstract：:The nutritional support of gastrointestinal growth and function is an important consideration in the clinical care of neonatal infants. In most health infants, the provision of either breast milk or formula seems to support normal intestinal mucosal growth, but the most significant advantages of breast milk may be for...

journal_title：Clinics in perinatology

authors： Burrin DG,Stoll B

更新日期：2002-03-01 00:00:00

abstract：:The last decades of bilirubin research seem to have clarified the basic mechanisms by which bilirubin enters the brain. Clinical studies have so far failed to show any value of the presently known risk factors in predicting bilirubin toxicity in the newborn infant, however. This indicates that bilirubin entry into the...

journal_title：Clinics in perinatology

authors： Bratlid D

更新日期：1990-06-01 00:00:00

abstract：:The lifespan risk of seizures is highest in the neonatal period. Current therapies have limited efficacy. Although the treatment of neonatal seizures has not changed significantly in the last several decades, there has been substantial progress in understanding developmental mechanisms that influence seizure generatio...

journal_title：Clinics in perinatology

authors： Jensen FE

更新日期：2009-12-01 00:00:00

abstract：:Each year, approximately 2.7 million babies die during the neonatal period; more than 90% of these deaths occur in developing countries, largely from preventable causes. The known, evidence-based, simple, low-cost interventions that may improve neonatal survival often have low or unknown baseline coverage rates. Gaps ...

journal_title：Clinics in perinatology

authors： Ehret DY,Patterson JK,Bose CL

更新日期：2017-09-01 00:00:00

abstract：:Congenital cytomegalovirus is the most common viral congenital infection, and affects up to 2% of neonates. Significant sequelae may develop after congenital cytomegalovirus, including hearing loss, cognitive defects, seizures, and death. Zika virus is an emerging virus with perinatal implications; a congenital Zika v...

journal_title：Clinics in perinatology

authors： Wood AM,Hughes BL

更新日期：2018-06-01 00:00:00

abstract：:When cystic hygroma is detected antenatally, the prognosis is usually poor, and intrauterine or neonatal death are common. This seems especially true for Turner syndrome (the largest etiologic group associated with cystic hygroma) and the lethal multiple pterygium syndromes. However, some fetuses with Turner syndrome,...

journal_title：Clinics in perinatology

authors： Edwards MJ,Graham JM Jr

更新日期：1990-09-01 00:00:00

abstract：:Birth injuries of the brachial plexus are fairly common, but the majority of affected newborns make quick recoveries without any specific intervention. A minority suffer more severe injuries that lead to varying degrees of life-long disability. Happily, modern microsurgical techniques permit reconstruction of certain ...

journal_title：Clinics in perinatology

authors： Piatt JH Jr

更新日期：2005-03-01 00:00:00

abstract：:The percentage of United States cesarean births increased from 20.7% in 1996 to 31.1% in 2006. Cesarean rates increased for women of all ages, race/ethnic groups, and gestational ages and in all states. Both primary and repeat cesareans have increased. Increases in primary cesareans in cases of "no indicated risk" hav...

journal_title：Clinics in perinatology

authors： MacDorman MF,Menacker F,Declercq E

更新日期：2008-06-01 00:00:00

abstract：:Two different care procedures are presented to raise the difficult question of whether we should completely reevaluate our paradigms of care in the perinatal period. In this thorough review, should we continue to use the same framework of beliefs in deciding on the benefits and risks of any care procedure? ...

journal_title：Clinics in perinatology

authors： Kennell JH,Klaus MH

更新日期：1988-12-01 00:00:00

abstract：:Neonatal stress responses have been investigated only in recent years. Term neonates mount substantial hormonal and metabolic responses, which are distinct from those of adult patients. These responses can be altered significantly by the effects of prematurity, the effects of graded surgical stress, and the anesthetic...

journal_title：Clinics in perinatology

authors： Anand KJ

更新日期：1990-03-01 00:00:00

abstract：:There are various causes for frequent desaturations in infants. Frequent hypoxemia is a significant change in clinical status and must be investigated carefully for possible etiology. When common extra-airway causes for desaturation are ruled out, one should attempt to distinguish between central apnea and obstructive...

journal_title：Clinics in perinatology

authors： Spitzer AR

更新日期：2007-03-01 00:00:00

abstract：:Staphylococci are common pathogens in the neonatal period. Increased survival of premature infants leads to prolonged hospital stay with associated risk factors for developing invasive staphylococcal disease. Challenges of diagnosing coagulase-negative staphylococcal infections result in conflicting definitions and in...

journal_title：Clinics in perinatology

authors： Blanchard AC,Quach C,Autmizguine J

更新日期：2015-03-01 00:00:00

abstract：:In the past, all women with a family history of breast or ovarian cancer were considered to be at increased risk of cancer themselves. The discovery of BRCA1 and BRCA2 demonstrated that susceptibility to breast and ovarian cancer can be inherited by women as a single-gene autosomal dominant disorder. For such women, e...

journal_title：Clinics in perinatology

authors： Frank TS,Critchfield GC

更新日期：2001-06-01 00:00:00

abstract：:Congenital heart disease (CHD) is an attractive target for fetal therapy. With the development of successful neonatal repair for many types of CHD over the last 20 years, fetal therapy has become the next frontier. Concurrent advances in interventional catheterization and fetal imaging provided a foundation for the no...

journal_title：Clinics in perinatology

authors： Turner CG,Tworetzky W,Wilkins-Haug LE,Jennings RW

更新日期：2009-06-01 00:00:00

abstract：:Babies of extremely low birthweight and elderly adults both require expensive and scarce resources, and both have a relatively poor prognosis for survival if they require intensive care. Thus, proposals for rationing often target one or both of these groups. We suspected that although mortality rates might be higher i...

journal_title：Clinics in perinatology

authors： Meadow W,Lantos JD,Mokalla M,Reimshisel T

更新日期：1996-09-01 00:00:00

abstract：:Obstetric ultrasound (US) is an integral part of fetal surgery for open and minimally invasive techniques. With advances in US imaging, the ability to refine diagnosis, predict prognosis, and contribute to fetal treatment continues to grow. Current research in fetal diagnosis and treatment includes identifying the mos...

journal_title：Clinics in perinatology

authors： Hopkins LM,Feldstein VA

更新日期：2009-06-01 00:00:00