Clinical implications of current developments in genitourinary pathology.

abstract：:Just as electronic health records are transforming the practice of medicine and health care information management, practicing in the era of the electronic health record offers opportunities, if not imperatives, for pathologists to take on new and "transformative" professional and leadership roles for the organization...

journal_title：Archives of pathology & laboratory medicine

authors： Henricks WH,Wilkerson ML,Castellani WJ,Whitsitt MS,Sinard JH

更新日期：2015-03-01 00:00:00

abstract：CONTEXT:Aperio Technologies, Inc (Vista, California) provides a new immunohistochemistry (IHC) HER2 Image Analysis (IA) system that allows tuning of the intensity thresholds of the HER2/ neu scoring scheme to adapt to the staining characteristics of different reagents. OBJECTIVE:To compare the trainable IHC HER2 IA sy...

journal_title：Archives of pathology & laboratory medicine

authors： Nassar A,Cohen C,Agersborg SS,Zhou W,Lynch KA,Albitar M,Barker EA,Vanderbilt BL,Thompson J,Heyman ER,Lange H,Olson A,Siddiqui MT

更新日期：2011-07-01 00:00:00

abstract：CONTEXT:Two recent studies have identified a high rate of microsatellite instability (MSI) in pancreatic neuroendocrine tumors (pNETs). Microsatellite instability is rare in small intestinal neuroendocrine tumors (NETs). It is unclear why there is discordance in the frequency of MSI in the 2 studies of pNETs and why th...

journal_title：Archives of pathology & laboratory medicine

authors： Arnason T,Sapp HL,Rayson D,Barnes PJ,Drewniak M,Nassar BA,Huang WY

更新日期：2011-12-01 00:00:00

abstract：:Nonneoplastic vascular lesions in lymph nodes have been infrequently reported. These lesions are believed to be rare and display histologic features ranging from minimal changes associated with vasodilation to vascular proliferative lesions resembling Kaposi's sarcoma. The spectrum of histologic features observed in t...

journal_title：Archives of pathology & laboratory medicine

authors： Ostrowski ML,Siddiqui T,Barnes RE,Howton MJ

更新日期：1990-07-01 00:00:00

abstract：:A small-cell carcinoma combined with adenocarcinoma of the gallbladder was detected in a 71-year-old Japanese woman. A nodular mass measuring 4.0 x 5.0 cm was located in the fundus of the gallbladder, in which a tiny depressed lesion measuring 2 mm in diameter was macroscopically and stereomicroscopically observed. Hi...

journal_title：Archives of pathology & laboratory medicine

authors： Nishihara K,Nagai E,Tsuneyoshi M,Nagashima M

更新日期：1994-02-01 00:00:00

abstract：CONTEXT:Recent studies have uncovered a number of possible mechanisms by which prostate cancers can become resistant to systemic androgen deprivation, most involving androgen-independent reactivation of the androgen receptor. Genome-wide expression analysis with microarrays has identified a wide array of genes that are...

journal_title：Archives of pathology & laboratory medicine

authors： Mackinnon AC,Yan BC,Joseph LJ,Al-Ahmadie HA

更新日期：2009-07-01 00:00:00

abstract：CONTEXT:Constipation or recurrent intestinal dysmotility problems are common after definitive surgical treatment in Hirschsprung disease (HD). c-Kit-positive interstitial cells of Cajal (ICCs) play a key role in the motility function and development of the gastrointestinal tract. Interstitial cells of Cajal that carry ...

journal_title：Archives of pathology & laboratory medicine

authors： Rolle U,Piotrowska AP,Nemeth L,Puri P

更新日期：2002-08-01 00:00:00

abstract：:Calbindin-D28k is a highly conserved 28,000 (dalton) molecular-weight (Mr) calcium binding protein with broad tissue distribution, yet cell-type-specific expression predominantly in subpopulations of central and peripheral nervous system neurons, distal tubular cells of the kidney, and enteric neuroendocrine cells. A ...

journal_title：Archives of pathology & laboratory medicine

authors： Katsetos CD,Jami MM,Krishna L,Jackson R,Patchefsky AS,Cooper HS

更新日期：1994-06-01 00:00:00

abstract：:Lymph node involvement by histiocytosis X is usually secondary to nearby bone or skin lesions. A patient with histiocytosis X confined to lymph nodes is rarely seen; however, we studied two such persons. In each, a lymph node biopsy was performed because the clinical aspects caused us to suspect neoplastic disease. ...

journal_title：Archives of pathology & laboratory medicine

authors： Sajjad SM,Osborne B

更新日期：1982-02-01 00:00:00

abstract：:von Hippel-Lindau (VHL) disease is an autosomal dominant disorder caused by heterozygous mutations in the VHL tumor suppressor gene that is characterized by the occurrence of multiple endocrine and nonendocrine lesions. This review focuses on the endocrine manifestations of VHL disease. Pancreatic neuroendocrine proli...

journal_title：Archives of pathology & laboratory medicine

authors： Cassol C,Mete O

更新日期：2015-02-01 00:00:00

abstract：:Ciliated hepatic foregut cysts are rare congenital lesions derived from the embryologic foregut. They are considered benign, and a review of 64 published cases revealed no instances of malignant transformation. We report a case of squamous cell carcinoma arising in a ciliated hepatic foregut cyst in a 51-year-old man....

journal_title：Archives of pathology & laboratory medicine

authors： Vick DJ,Goodman ZD,Ishak KG

更新日期：1999-11-01 00:00:00

abstract：:We performed x-ray microanalysis of autopsy specimens using a scanning-transmission electron microscopy mode. Tissues were obtained at necropsy from a patient with history of angiography using thorium dioxide and from a patient with hemochromatosis. X-ray microanalysis confirmed the presence of thorium and iron in the...

journal_title：Archives of pathology & laboratory medicine

authors： Landas S,Turner JW,Moore KC,Mitros FA

更新日期：1984-03-01 00:00:00

abstract：OBJECTIVES:To establish the rates with which reference laboratories resolve inquiries telephoned to them from primary laboratories and to identify reference laboratory practices associated with higher rates of inquiry resolution. DESIGN AND PARTICIPANTS:For 2 months, or until 50 contacts had occurred, 545 primary labo...

journal_title：Archives of pathology & laboratory medicine

authors： Dale JC,Novis DA,Meier FA

更新日期：2001-05-01 00:00:00

abstract：CONTEXT:Since 1988, the College of American Pathologists has been offering materials for calibration verification coupled with the surveys for linearity, called the linearity (LN) surveys. OBJECTIVE:To determine whether successful completion of the College of American Pathologists LN surveys provides a benefit in term...

journal_title：Archives of pathology & laboratory medicine

authors： Kroll MH,Styer PE,Vasquez DA

更新日期：2004-05-01 00:00:00

abstract：CONTEXT:The College of American Pathologists Cancer Case Summaries templates provide a method for including all necessary pathology information in surgical pathology reports with cancer. How effective these templates are at ensuring a complete report, as measured by a separate outside tumor registry, is not known. OBJ...

journal_title：Archives of pathology & laboratory medicine

authors： Renshaw SA,Mena-Allauca M,Touriz M,Renshaw A,Gould EW

更新日期：2014-01-01 00:00:00

abstract：:To examine the role of sputum examination in the diagnosis of Pneumocystis carinii pneumonia in patients with the acquired immunodeficiency syndrome (AIDS), we conducted a prospective study of 30 patients with AIDS or suspected AIDS. Sputum was obtained just prior to bronchoscopy by spontaneous cough (20 patients) or ...

journal_title：Archives of pathology & laboratory medicine

authors： del Rio C,Guarner J,Honig EG,Slade BA

更新日期：1988-12-01 00:00:00

abstract：:Aspiration biopsy cytology (ABC) specimens were obtained from 540 patients by transrectal biopsy because of suspicious lesions or metastases from occult carcinoma. Although poorly differentiated prostatic carcinoma had previously presented few diagnostic problems by ABC, cells from well-differentiated adenocarcinoma h...

journal_title：Archives of pathology & laboratory medicine

authors： Kline TS,Kohler FP,Kelsey DM

更新日期：1982-03-01 00:00:00

abstract：:Clear cell sarcoma shares features with melanoma, but frequently shows EWSR1 rearrangements. It is an aggressive tumor typically occurring in the soft tissues of the extremities, with a gastrointestinal variant with less consistent melanocytic differentiation. It is extremely rare in the head and neck region, with no ...

journal_title：Archives of pathology & laboratory medicine

authors： Kraft S,Antonescu CR,Rosenberg AE,Deschler DG,Nielsen GP

更新日期：2013-11-01 00:00:00

abstract：:The costs of producing quality medical care and the proper allocation of resources to assure quality are major contemporary concerns. Minimalists attempt to improve quality and lower costs through the application of the theory, "less is more." Bureaucracies make the same attempt through the denial of payments for "unn...

journal_title：Archives of pathology & laboratory medicine

authors： Lambird PA

更新日期：1990-11-01 00:00:00

abstract：:We report a case of primary cerebral lymphoma metastasizing to the kidney with exclusive involvement of the glomeruli. We discuss the possible explanations of this unusual phenomenon, and present some of the unusual clinical features of the case. Nephropathologists interpreting glomerular hypercellularity should alway...

journal_title：Archives of pathology & laboratory medicine

authors： Iskandar SS,Jennette JC,Weis LS

更新日期：1985-06-01 00:00:00

abstract：:Blood banks and transfusion services should anticipate that patients contracting transfusion-transmitted diseases will claim that these facilities have a duty to warn or notify patients of potential transfusion risks. Although physicians treating patients must secure informed consent by describing significant risks an...

journal_title：Archives of pathology & laboratory medicine

authors： Willett DE

更新日期：1989-03-01 00:00:00

abstract：CONTEXT:Pretransfusion testing of whole blood and red blood cell recipients is regulated by the federal government under the authority of the Clinical Laboratory Improvement Amendments of 1988. Regulated tests include determination of ABO group, Rh D type, antibody detection, antibody identification, and crossmatching....

journal_title：Archives of pathology & laboratory medicine

authors： Shulman IA,Maffei LM,Downes KA

更新日期：2005-08-01 00:00:00

abstract：CONTEXT:In gastric cancer, the significance of perineural invasion remains controversial. Detecting perineural invasion with hematoxylin-eosin staining often leads to misdiagnosis. Labeling nerves by immunohistochemistry greatly assists perineural invasion detection, but it might also be misdiagnosed, because scattered...

journal_title：Archives of pathology & laboratory medicine

authors： Zhou ZH,Xu GF,Zhang WJ,Zhao HB,Wu YY

更新日期：2014-02-01 00:00:00

abstract：CONTEXT:The endomyocardial biopsy is the mainstay for monitoring acute allograft rejection in heart transplantation. Objective and accurate assessment of cellular and humoral types of rejection is important to optimize immunosuppressive therapy, avoid therapeutic complications, and improve patient outcome. The grading ...

journal_title：Archives of pathology & laboratory medicine

authors： Tan CD,Baldwin WM 3rd,Rodriguez ER

更新日期：2007-08-01 00:00:00

abstract：:Laboratories participating in the College of American Pathologists Enzyme Survey (ES) and Comprehensive Chemistry Survey used diverse methods for the same analyte, resulting in a considerable range of values for the commonly performed enzyme measurements. Nevertheless, with the techniques developed for the ES, both th...

journal_title：Archives of pathology & laboratory medicine

authors： Lott JA,Tholen DW,Massion CG

更新日期：1988-04-01 00:00:00

abstract：:We reviewed 36 body fluid specimens from 18 patients with Hodgkin's disease (HD) to characterize the cytologic features of HD as seen in Wright-Giemsa (WG)-stained cytocentrifuge preparations, and to compare diagnostic agreement between WG- and Papanicolaou-stained samples. Slides were examined independently by two pa...

journal_title：Archives of pathology & laboratory medicine

authors： Wilson MS,Theil KS,Goodwin RA,Brandt JT

更新日期：1988-06-01 00:00:00

abstract：OBJECTIVE:The pathogenesis of appendicitis remains poorly understood. However, there is increasing evidence of involvement of the enteric nervous system in immune regulation and in inflammatory responses. This study was set up to characterize the status of the enteric nervous system in normal and in inflamed appendixes...

journal_title：Archives of pathology & laboratory medicine

authors： Xiong S,Puri P,Nemeth L,O'Briain DS,Reen DJ

更新日期：2000-10-01 00:00:00

abstract：CONTEXT:Increased thymidylate synthase expression is a marker for decreased survival in colorectal cancer. OBJECTIVE:Thymidylate synthase localizes to both the nucleus and cytoplasm, but how the relationship of these expression levels affects colon cancer outcome has yet to be determined. DESIGN:Using AQUA, we assess...

journal_title：Archives of pathology & laboratory medicine

authors： Gustavson MD,Molinaro AM,Tedeschi G,Camp RL,Rimm DL

更新日期：2008-11-01 00:00:00

abstract：CONTEXT:Although the healthy esophageal mucosa contains no eosinophils, eosinophilic infiltration is observed in 2 major clinicopathologic settings: gastroesophageal reflux disease (GERD) and eosinophilic esophagitis (EE). The prevalence of EE is increasing in many countries, and this increase seems only partly to be d...

journal_title：Archives of pathology & laboratory medicine

authors： Genevay M,Rubbia-Brandt L,Rougemont AL

更新日期：2010-06-01 00:00:00

abstract：CONTEXT.—:Related to the advances in prenatal diagnosis and the emergence of medically challenging situations, there has been an increased interest in conducting a pathologic study of first-trimester abortion products. OBJECTIVE.—:To evaluate measurements across a large group of first-trimester spontaneous abortion sp...

journal_title：Archives of pathology & laboratory medicine

authors： Nogueira R,Sousa S,Braga AC,Azevedo A,Pereira N,Carmo O,Tavares MP,Pinto JC

更新日期：2020-02-01 00:00:00