Antibody to the host cellular gene-derived epitope GOR-1 in liver transplant recipients with hepatitis C virus infection.

abstract：BACKGROUND:To reduce the morbidity of living kidney donors we introduced ketorolac-based analgesia for patients undergoing open donor nephrectomy in August 1999. There are no prior reports on the use of ketorolac for patients undergoing donor nephrectomy. METHODS:We conducted a retrospective review of all 198 consecut...

journal_title：Transplantation

authors： Freedland SJ,Blanco-Yarosh M,Sun JC,Hale SJ,Elashoff DA,Litwin MS,Smith RB,Rajfer J,Gritsch HA

更新日期：2002-03-15 00:00:00

abstract：:As a first step in the study of the possible relationship between the T/t and H-2 complexes, the H-2 antigenic composition of the strains carrying factors t12, tw32, tw2, tw8, t1, t0, t6, tw1, tw71, tw73, tw12, tw5, tw75, and t38 was studied by using a battery of antisera containing antibodies against inbred-derived H...

journal_title：Transplantation

authors： Hammerberg C,Klein J,Artzt K,Bennett D

更新日期：1976-03-01 00:00:00

abstract：:The recipients of combined kidney-pancreas transplants (SPK) are unique because they routinely receive two allografts from the same donor. In a previous study, we found that the long-term graft survival of the two allografts was different, with better graft survival seen in the pancreas allograft. In an attempt to und...

journal_title：Transplantation

authors： Tesi RJ,Henry ML,Elkhammas EA,Davies EA,Ferguson RM

更新日期：1994-08-27 00:00:00

abstract：BACKGROUND:Cardiopulmonary resuscitation (CPR) of a person destined to become an organ donor has been associated with overall poor donor quality, especially for the intestinal donor, as splanchnic vasoconstriction that is intended to preserve coronary and cerebral blood flow may result in clinically relevant intestinal...

journal_title：Transplantation

authors： Matsumoto CS,Kaufman SS,Girlanda R,Little CM,Rekhtman Y,Raofi V,Laurin JM,Shetty K,Fennelly EM,Johnson LB,Fishbein TM

更新日期：2008-10-15 00:00:00

abstract：BACKGROUND:Obliterative bronchiolitis (OB), chronic allograft rejection of the lung, is a major cause of morbidity and mortality after lung transplantation. Previous studies using the heterotopic mouse trachea model of chronic airway rejection have shown a T cell infiltrate composed of CD4+ and CD8+ T cells. The goal o...

journal_title：Transplantation

authors： Neuringer IP,Walsh SP,Mannon RB,Gabriel S,Aris RM

更新日期：2000-02-15 00:00:00

abstract：BACKGROUND:Two patients with end-stage renal disease secondary to multiple myelomas were treated with combined kidney and bone marrow transplantation in an effort to achieve donor-specific allotolerance through the induction of mixed lymphohematopoietic chimerism. METHODS:Two female patients (55 and 50 years of age) w...

journal_title：Transplantation

authors： Bühler LH,Spitzer TR,Sykes M,Sachs DH,Delmonico FL,Tolkoff-Rubin N,Saidman SL,Sackstein R,McAfee S,Dey B,Colby C,Cosimi AB

更新日期：2002-11-27 00:00:00

abstract：BACKGROUND:The authors have previously demonstrated that inhibition of CD28 and CD40 ligand (CD40L) co-stimulatory signals by adenovirus-mediated cytotoxic T-lymphocyte-associated (CTL) antigen 4 (A4) immunoglobulin (Ig) and CD40Ig gene therapies induces tolerance or long-term acceptance in rat liver and heart allograf...

journal_title：Transplantation

authors： Hua N,Yamashita K,Hashimoto T,Masunaga T,Fujita M,Furukawa H,Uede T,Todo S

更新日期：2004-11-27 00:00:00

abstract：BACKGROUND:Recent studies have described submandibular gland allografts in animal models; however, the amount of saliva secretion or nervous regeneration in those animals have not been reported. Herein, we investigated saliva secretion from submandibular gland allografts in beagle dogs. METHODS:Using a vascularized su...

journal_title：Transplantation

authors： Isomura ET,Yoshitomi K,Hamaguchi M,Kogo M

更新日期：2007-03-27 00:00:00

abstract：:Retrospective mixed leukocyte culture studies were performed in eight patients who had either rejected their marrow grafts or experienced graft-versus-host disease and in seven patients with successful marrow engraftment. In tests of pre-and post-transplant lymphocytes we found no evidence that rejection or graft-vers...

journal_title：Transplantation

authors： Opelz G,Gale RP

更新日期：1976-11-01 00:00:00

abstract：:Since the earliest days of transplantation, immunobiologists have sought means to prevent recognition and rejection of foreign tissue. The goal of these strategies is the retention of recipient immune function while selectively avoiding graft injury. Although considerable theoretical and technical problems remain, an ...

journal_title：Transplantation

authors： Lynch RJ,Platt JL

更新日期：2009-12-15 00:00:00

abstract：:Adhesion of leukocytes to vascular endothelium is a necessary step leading to the migration of cells into underlying tissues. Vascular adhesion molecules regulate this process and may play an important role in graft rejection. Immunocytochemical studies have been used to investigate the expression of vascular adhesion...

journal_title：Transplantation

authors： Taylor PM,Rose ML,Yacoub MH,Pigott R

更新日期：1992-09-01 00:00:00

abstract：:Long-term graft survival is mainly influenced by early graft rejection and posttransplant graft function. The ability of both complement-dependent cytotoxicity cross-match (CDC) and flow cytometry cross-match (FCXM) to predict acute rejection episodes has been evaluated by cross-matching 40 patients who received cadav...

journal_title：Transplantation

authors： Utzig MJ,Blümke M,Wolff-Vorbeck G,Lang H,Kirste G

更新日期：1997-02-27 00:00:00

abstract：:Discordant xenogeneic organ transplantation is a potential solution to the critical shortage of suitable donor organs. However, clinical application of xenotransplantation with physiologically suitable organs such as those from the pig, is currently limited by the lack of agents to prevent antibody and complement-medi...

journal_title：Transplantation

authors： Kennedy SP,Rollins SA,Burton WV,Sims PJ,Bothwell AL,Squinto SP,Zavoico GB

更新日期：1994-05-27 00:00:00

abstract：BACKGROUND:Inasmuch as cryopreservation can facilitate clinical islet transplantation by providing a means of storing supplemental islets in order to augment marginally adequate grafts, protocols are needed to allow for a minimal loss in viable beta cells. By replacing the cryoprotectant dimethyl sulfoxide (DMSO) with ...

journal_title：Transplantation

authors： Korbutt GS,Rayat GR,Ezekowitz J,Rajotte RV

更新日期：1997-10-15 00:00:00

abstract：BACKGROUND:The increasing demand for transplantation has resulted in a trend toward using virologically compromised donors. We reviewed our experience with liver grafts from hepatitis-B surface antigen (HBsAg)(-), antibody to core antigen (anti-HBc)(+) donors. METHODS:Sixty-two liver transplants using HBsAg(-), anti-H...

journal_title：Transplantation

authors： Nery JR,Nery-Avila C,Reddy KR,Cirocco R,Weppler D,Levi DM,Nishida S,Madariaga J,Kato T,Ruiz P,Schiff E,Tzakis AG

更新日期：2003-04-27 00:00:00

abstract：:Acute rejection episodes still occur after kidney transplantation in spite of modern immunosuppressive protocols including combined tacrolimus, mycophenolate mofetil, and prednisolone. The authors present seven cases of biopsy-proven acute rejection after kidney transplantation refractory to conventional rejection the...

journal_title：Transplantation

authors： Kumlien G,Genberg H,Shanwell A,Tydén G

更新日期：2005-01-15 00:00:00

abstract：:The histopathological changes and the course of graft-versus-host (GVH) disease were studied in the rat model of small-bowel transplantation using the Lewis----LBN-F1 strain combination. Allograft-induced GVH disease led to the recipients' death from enteritis, dermatitis and emaciation after 14.4 +/- 2.9 days (hetero...

journal_title：Transplantation

authors： Schraut WH,Lee KK,Dawson PJ,Hurst RD

更新日期：1986-03-01 00:00:00

abstract：BACKGROUND:Calcineurin is a ubiquitously expressed calcium-dependent phosphatase that is inhibited by the immunosuppressant drugs cyclosporine and tacrolimus. Measuring calcineurin activity in transplant patients has been complicated by a lack of consistent correlation between drug level and enzyme activity, particular...

journal_title：Transplantation

authors： Pena JA,Titus L,Jackson J,Kirk AD,Gooch JL

更新日期：2013-08-15 00:00:00

abstract：:We developed a new and simplified donor-specific blood transfusion (DSBT) protocol for prospective kidney transplant recipients from one-haplotype-mismatched related donors. Prospective kidney donors gave 450 ml of blood in a quad-pack unit, and the blood was stored in a blood bank. Twenty-five patients were transfuse...

journal_title：Transplantation

authors： Cheigh JS,Suthanthiran M,Kaplan M,Evelyn M,Riggio RR,Fotino M,Schechter N,Wolf CF,Stubenbord WT,Stenzel KH

更新日期：1984-11-01 00:00:00

abstract：:In a prospective longitudinal study, detection of cytomegalovirus (CMV) DNA in plasma (plasma polymerase chain reaction [PCR]) was compared with PCR of CMV DNA in peripheral blood leukocytes (PBL PCR), the CMV pp65 antigenemia assay, and viral cultures from blood, urine, and throat of 29 patients, 14 of whom received ...

journal_title：Transplantation

authors： Boeckh M,Gallez-Hawkins GM,Myerson D,Zaia JA,Bowden RA

更新日期：1997-07-15 00:00:00

abstract：:The immunosuppressive effects of leflunomide and cyclosporine were evaluated in a rat neurovascularized myocutaneous allograft model. Inbred Brown-Norway and Lewis rats were served as donors and recipients, respectively. All recipients were observed for 60 days or until allograft rejection occurred. All isograft contr...

journal_title：Transplantation

authors： Yeh LS,Gregory CR,Griffey SM,Lecouteur RA,Morris RE

更新日期：1996-09-27 00:00:00

abstract：BACKGROUND:Increased numbers of macrophages and myofibroblasts are observed to occur in chronic renal allograft rejection (CR). The aim of this study was to examine the expression of cellular markers for the macrophage and myofibroblast in early renal transplant biopsy specimens and correlate these findings with allogr...

journal_title：Transplantation

authors： Pilmore HL,Painter DM,Bishop GA,McCaughan GW,Eris JM

更新日期：2000-06-27 00:00:00

abstract：:Osteopetrotic microphthalmic mice (mi/mi) were treated by injections of suspensions of myeloid tissue, newborns i.p., and weanlings i.v. Donated syngeneic material effected permanent cure of oteopetrosis provided that the dose was large enough (10(8) cells of bone marrow). H-2-compatible allogeneic bone marrow was ini...

journal_title：Transplantation

authors： Nisbet NW,Menage J,Loutit JF

更新日期：1979-10-01 00:00:00

abstract：BACKGROUND:The use of lung grafts from non-heart-beating donors (NHBD) is one way of solving the donor organ shortage problem. In this experiment, we studied the effect of retrograde flush (RF) from the left atrium before harvest, inhaled nitric oxide (NO), and gabexate mesilate (FOY), a protease inhibitor, in the lung...

journal_title：Transplantation

authors： Luh SP,Tsai CC,Shau WY,Chen JS,Kuo SH,Lin-Shiau SY,Lee YC

更新日期：2000-05-27 00:00:00

abstract：BACKGROUND:Proteinuria is associated with endothelial dysfunction (ED) and increased mortality. We investigated whether urinary protein excretion (UPE) is correlated with markers of ED and whether these markers affect the association of proteinuria with mortality in renal transplant recipients (RTR). METHODS:Six hundr...

journal_title：Transplantation

authors： van Ree RM,Oterdoom LH,de Vries AP,Homan van der Heide JJ,van Son WJ,Navis G,Gans RO,Bakker SJ

更新日期：2008-12-27 00:00:00

abstract：:Renal transplantation after repair of aortoiliac aneurysms with traditional prosthetic vascular grafts has been shown to be effective. Vascular surgery continues to rapidly evolve, most notably with the advancement of endovascular repair of abdominal aortic aneurysms. Controlled trials continue to support the trend to...

journal_title：Transplantation

authors： George P,Tan HP,Beebe H,Ratner LE

更新日期：2001-08-15 00:00:00

abstract：:Rapamycin prolongs allograft survival and induces donor-specific tolerance in some small animal transplant models. Large animal studies, however, are limited. We studied rapamycin in a porcine renal allograft model. Donor-recipient combinations were chosen based on high response in pretransplant MLCs. Allografts were ...

journal_title：Transplantation

authors： Almond PS,Moss A,Nakhleh RE,Melin M,Chen S,Salazar A,Shirabe K,Matas AJ

更新日期：1993-08-01 00:00:00

abstract：:Based on a log-linear model for analyzing multiple effects, center variation in the UCLA Transplant Registry is the most influential factor in early renal graft survival. Among 68 active centers accounting for 70% of all transplants between 1985 and 1989, the 1-year graft survival (adjusted for 15 covariates) varied f...

journal_title：Transplantation

authors： Gjertson DW,Terasaki PI

更新日期：1992-02-01 00:00:00

abstract：:In a three-year period between January 1980 and December 1982, 242 consecutive cadaver transplant recipients in one center were tested before transplantation by cytotoxicity against a random panel of T and B lymphocytes at 5 degrees C and 37 degrees C incubation. They were also tested for HLA-A, B, and DR antigens. Ki...

journal_title：Transplantation

authors： Mendez R,Chatterjee SN,Mendez R,Bogaard T

更新日期：1985-09-01 00:00:00

abstract：BACKGROUND:In nontransplant patients with chronic hepatitis C virus (HCV), HCV genotype has been linked with a differential response to antiviral therapy, risk of steatosis and fibrosis, as well as all-cause mortality, but the role of HCV genotypes in posttransplant disease progression is less clear. METHODS:Using the...

journal_title：Transplantation

authors： Campos-Varela I,Lai JC,Verna EC,O'Leary JG,Todd Stravitz R,Forman LM,Trotter JF,Brown RS,Terrault NA,Consortium to Study Health Outcomes in HCV Liver Transplant Recipients (CRUSH-C).

更新日期：2015-04-01 00:00:00