当前位置： SCI文献检索 > TRANSPLANTATION期刊下所有文献 > Utilization of donors who have suffered cardiopulmonary arrest and resuscitation in intestinal transplantation.

Utilization of donors who have suffered cardiopulmonary arrest and resuscitation in intestinal transplantation.

Abstract：

BACKGROUND:Cardiopulmonary resuscitation (CPR) of a person destined to become an organ donor has been associated with overall poor donor quality, especially for the intestinal donor, as splanchnic vasoconstriction that is intended to preserve coronary and cerebral blood flow may result in clinically relevant intestinal ischemia. Outcomes of recipients who receive intestine grafts that have suffered CPR are unknown. We sought to analyze our clinical experience in using intestinal grafts from donors who suffered cardiopulmonary arrest and resuscitation and to evaluate the outcome of recipients of organs coming from resuscitated donors when compared with recipients of nonresuscitated donors. METHODS:We retrospectively analyzed the donor and recipient charts of all of our intestinal transplants with regard to the performance of donor CPR. RESULTS:Sixty-seven intestinal transplants were performed in 65 patients from November 2003 to December 2007. Twelve donors (18%) were identified as having suffered cardiac arrest and subsequent CPR. Mean duration of CPR was 19.3+/-12.7 min. Terminal laboratory profiles of CPR donors and non-CPR donors were similar. Of the 12 resuscitated grafts, two were used for multivisceral, one for a modified multivisceral, seven for liver-intestine, and two for isolated intestinal transplant. There were no significant differences in outcome parameters such as operative time, blood use, ventilation days, length of stay, time to enteral independence, rejection, enteric bacteremia, and survival between the 12 resuscitated grafts and the 55 nonresuscitated grafts. CONCLUSION:A donor history of cardiac arrest should not automatically exclude the use of the intestine graft for transplantation.

journal_name

Transplantation

journal_title

Transplantation

authors

Matsumoto CS,Kaufman SS,Girlanda R,Little CM,Rekhtman Y,Raofi V,Laurin JM,Shetty K,Fennelly EM,Johnson LB,Fishbein TM

doi

10.1097/TP.0b013e3181852f9a

subject

Has Abstract

pub_date

2008-10-15 00:00:00

pages

941-6

issue

7

eissn

0041-1337

issn

1534-6080

pii

00007890-200810150-00012

journal_volume

86

pub_type

杂志文章

相关文献

TRANSPLANTATION文献大全
  • Stage I adenocarcinoma presenting in the pneumonectomy specimen at the time of single lung transplantation.

    abstract：:Two patients at our institution underwent single lung transplantation. The procedure and the patient's postoperative course were uncomplicated in each case. Pathological examination of each pneumonectomy specimen revealed a well-differentiated adenocarcinoma; both were less than 1 cm in size. The remainder of each lun...

    journal_title：Transplantation

    pub_type： 杂志文章

    doi：10.1097/00007890-199810270-00024

    authors： Svendsen CA,Bengtson RB,Park SJ,Shumway SJ

    更新日期：1998-10-27 00:00:00

  • Tendinitis--a common complication after renal transplantation.

    abstract：:A group of 170 patients having functional renal allografts were evaluated at least six months after renal transplantation. They were assessed for symptoms and signs of tendinitis in the Achilles and Supraspinatus tendons. Of the 170 patients, 34 had tendinitis. Four patients (11.8%) had spontaneous rupture of the Achi...

    journal_title：Transplantation

    pub_type： 杂志文章

    doi：

    authors： Murison MS,Eardley I,Slapak M

    更新日期：1989-10-01 00:00:00

  • Prolongation of liver allograft survival after interleukin-10 gene transduction 24-48 hours before donation.

    abstract：BACKGROUND:Interleukin- (IL) 10 may be a potent regulator for controlling of allograft rejection. A single administration of IL-10 is not effective for controlling graft rejection. Gene transfer is an attractive vehicle for prolonging the expression of short-lived proteins. METHODS:Donor or recipient livers were trans...

    journal_title：Transplantation

    pub_type： 杂志文章

    doi：10.1097/00007890-200007270-00018

    authors： Tashiro H,Shinozaki K,Yahata H,Hayamizu K,Okimoto T,Tanji H,Fudaba Y,Yamamoto H,Fan X,Ito H,Asahara T

    更新日期：2000-07-27 00:00:00

  • The management of T tube leaks in orthotopic liver transplant recipients with endoscopically placed nasobiliary catheters.

    abstract：:Biliary tract problems remain an important cause of complication following orthotopic hepatic transplantation. We describe 12 liver transplantation patients who developed bile peritonitis secondary to a biliary leak after T tube removal. Each of these patients underwent an urgent ERCP that exhibited leakage outside th...

    journal_title：Transplantation

    pub_type： 杂志文章

    doi：10.1097/00007890-199005000-00018

    authors： Ostroff JW,Roberts JP,Gordon RL,Ring EJ,Ascher NL

    更新日期：1990-05-01 00:00:00

  • Immune dysfunction associated with graft-versus-host reaction in mice transplanted across minor histocompatibility barriers. I. Depressed antigen-specific antibody responses to bacteriophage phi chi 174.

    abstract：:The effect of the graft-versus-host reaction in response to minor histocompatibility antigens on the antibody response to a T-dependent antigen was studied in four strains of mice. Lethally irradiated mice were transplanted with bone marrow plus graded numbers of spleen cells from H-2-compatible donors. Recipients of ...

    journal_title：Transplantation

    pub_type： 杂志文章

    doi：10.1097/00007890-198906000-00029

    authors： Hamilton BL,Ochs HD

    更新日期：1989-06-01 00:00:00

  • In situ expression of tumor necrosis factor-alpha, interferon-gamma, and interleukin-2 receptors in renal allograft biopsies.

    abstract：:The production and release of cytokines and their receptors are of critical importance in mediating graft injury. In order to evaluate the expression of cytokines in renal allograft biopsies, we performed immunocytochemical studies to detect activated cells positive for TNF-alpha, IFN-gamma, and IL-2R, using an alkali...

    journal_title：Transplantation

    pub_type： 杂志文章

    doi：10.1097/00007890-199212000-00015

    authors： Noronha IL,Eberlein-Gonska M,Hartley B,Stephens S,Cameron JS,Waldherr R

    更新日期：1992-12-01 00:00:00

  • Liver transplantation in the first three months of life.

    abstract：BACKGROUND:Pediatric liver transplant recipients have traditionally been grouped according to age. Age-based classification schemes are useful in identifying clinical problems in selected age groups and also for developing solutions to these problems. Although infants in the first 3 months of life have not traditionall...

    journal_title：Transplantation

    pub_type： 杂志文章

    doi：10.1097/00007890-199809150-00010

    authors： Woodle ES,Millis JM,So SK,McDiarmid SV,Busuttil RW,Esquivel CO,Whitington PF,Thistlethwaite JR

    更新日期：1998-09-15 00:00:00

  • Absorption of shed I-Ak and H-2Kk antigens by lymphoid cells.

    abstract：:The fate of cell surface I-Ak and H-2Kk antigens shed by murine spleen cells in culture was studied by incubation of nonlabeled spleen cells or splenic T or B cells with culture fluids containing shed radiolabeled alloantigens. Approximately 30 to 40% of the shed alloantigens could be absorbed by syngeneic or allogene...

    journal_title：Transplantation

    pub_type： 杂志文章

    doi：10.1097/00007890-198201000-00008

    authors： Emerson SG,Cone RE

    更新日期：1982-01-01 00:00:00

  • Ranolazine--a new drug with beneficial effects on renal preservation.

    abstract：:Ranolazine is a new drug with a novel mode of action as a metabolic modulator and membrane stabilizer. In this prospective randomized double-blind trial, a porcine model of renal autotransplantation was used to assess the effects of this drug during preservation and reperfusion of kidneys cold-stored for 24 hr in phos...

    journal_title：Transplantation

    pub_type： 杂志文章

    doi：10.1097/00007890-199011000-00004

    authors： Lodge JP,Lam FT,Perry SL,Giles GR

    更新日期：1990-11-01 00:00:00

  • The effect of idarubicin monoclonal antibody treatment of first-set rejection of murine skin allografts.

    abstract：:Idarubicin was conjugated to anti-Ly-2.1 and anti-L3T4 monoclonal antibodies. These conjugates were used to investigate their effects on skin graft survival in mice. Several donor and recipient combinations were used so that the effect of individual or mixtures of conjugates on class I and class II antigenic differenc...

    journal_title：Transplantation

    pub_type： 杂志文章

    doi：10.1097/00007890-198907000-00018

    authors： Smyth MJ,McKenzie IF,Pietersz GA

    更新日期：1989-07-01 00:00:00

  • Specificity of cellular migration into cardiac allografts in rats.

    abstract：:The question has not been previously investigated as to whether host lymphocytes infiltrate vascularized organ allografts in indiscriminate fashion, or whether they are retained selectively because of specific antigenic recognition sites on their surfaces. By using a dual cardiac allograft model in LEW rats, we have e...

    journal_title：Transplantation

    pub_type： 杂志文章

    doi：10.1097/00007890-197809000-00011

    authors： Tilney NL,Notis-McConarty J,Strom TB

    更新日期：1978-09-01 00:00:00

  • Predictors of graft survival in pediatric living-related kidney transplant recipients.

    abstract：BACKGROUND:A successful kidney transplant from a living-related donor (LRD) remains the most effective renal replacement therapy for children with end-stage renal failure. The use of LRD kidneys results in decreased time on dialysis, increased graft survival, and better function compared with kidneys transplanted from ...

    journal_title：Transplantation

    pub_type： 杂志文章

    doi：10.1097/00007890-200007270-00008

    authors： Ishitani M,Isaacs R,Norwood V,Nock S,Lobo P

    更新日期：2000-07-27 00:00:00

  • Recipients' perceptions of their transplanted kidneys.

    abstract：BACKGROUND:The literature indicates few studies on kidney patients' perception of the donor kidney. In light of this fact, we decided to explore this issue with adult patients. METHODS:We carried out a phenomenological study with 40 adult kidney patients. RESULTS:In this study, three main themes became apparent: the ...

    journal_title：Transplantation

    pub_type： 杂志文章

    doi：10.1097/01.tp.0000168149.95310.6e

    authors： Buldukoglu K,Kulakac O,Kececioglu N,Alkan S,Yilmaz M,Yucetin L

    更新日期：2005-08-27 00:00:00

  • Renal ischemia-reperfusion induces release of angiopoietin-2 from human grafts of living and deceased donors.

    abstract：BACKGROUND:Recent insights suggest that endothelial cell (EC) activation plays a major role in renal ischemia-reperfusion (I/R) injury. Interactions between ECs and pericytes via signaling molecules, including angiopoietins, are involved in maintenance of the vascular integrity. Experimental data have shown that enhanc...

    journal_title：Transplantation

    pub_type： 杂志文章

    doi：10.1097/TP.0b013e31829854d5

    authors： de Vries DK,Khairoun M,Lindeman JH,Bajema IM,de Heer E,Roest M,van Zonneveld AJ,van Kooten C,Rabelink TJ,Schaapherder AF,Reinders ME

    更新日期：2013-08-15 00:00:00

  • Inability of isolated soluble interleukin-2 receptor levels to predict biopsy rejection scores after heart transplantation.

    abstract：:Successful cardiac transplantation requires suppression of rejection, and endomyocardial biopsy is generally used to quantify this and guide immunotherapy. Biopsy, however, is an invasive, costly, cardiac catheterization with repetition limited. Since rejection requires lymphocyte activation, an alternative method of ...

    journal_title：Transplantation

    pub_type： 杂志文章

    doi：10.1097/00007890-199103000-00018

    authors： Young JB,Windsor NT,Smart FW,Kleiman NS,Weilbaecher DG,Noon GP,Nelson DL,Lawrence EC

    更新日期：1991-03-01 00:00:00

  • Randomized trial of tacrolimus + mycophenolate mofetil or azathioprine versus cyclosporine + mycophenolate mofetil after cadaveric kidney transplantation: results at three years.

    abstract：METHODS:Two hundred twenty-three recipients of first cadaveric kidney allografts were randomized to receive tacrolimus (TAC) + mycophenolate mofetil (MMF), TAC + azathioprine (AZA), or cyclosporine (Neoral; CsA) + MMF. All regimens contained corticosteroids, and antibody induction was used only in patients who experien...

    journal_title：Transplantation

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1097/01.TP.0000069831.76067.22

    authors： Gonwa T,Johnson C,Ahsan N,Alfrey EJ,Halloran P,Stegall M,Hardy M,Metzger R,Shield C 3rd,Rocher L,Scandling J,Sorensen J,Mulloy L,Light J,Corwin C,Danovitch G,Wachs M,VanVeldhuisen P,Leonhardt M,Fitzsimmons WE

    更新日期：2003-06-27 00:00:00

  • Sodium-hydrogen exchanger inhibition, pharmacologic ischemic preconditioning, or both for extended cardiac allograft preservation.

    abstract：BACKGROUND:The aim of this study was to determine the efficacy of cariporide (a sodium-hydrogen exchanger inhibitor), BMS180448 (a pharmacologic ischemic preconditioning agent), and the combination thereof, as adjuvant therapies for extended cardiac allograft preservation. METHODS:A porcine model of donor brain death ...

    journal_title：Transplantation

    pub_type： 杂志文章

    doi：10.1097/01.TP.0000079254.81264.6D

    authors： Ryan JB,Hicks M,Cropper JR,Garlick SR,Kesteven SH,Wilson MK,Feneley MP,Macdonald PS

    更新日期：2003-09-15 00:00:00

  • Treatment of patients with recurrent hepatitis C after liver transplantation with peginterferon alfa-2B plus ribavirin.

    abstract：BACKGROUND:Recurrent hepatitis C virus (HCV) after liver transplantation (OLT) is a major cause of graft loss in HCV-positive patients. In this study, we evaluated the efficacy and safety of pegylated interferon alfa-2b (peginterferon) and ribavirin treatment for recurrent HCV after OLT and analyzed the influence of an...

    journal_title：Transplantation

    pub_type： 临床试验,杂志文章

    doi：10.1097/01.tp.0000225827.18034.be

    authors： Neumann U,Puhl G,Bahra M,Berg T,Langrehr JM,Neuhaus R,Neuhaus P

    更新日期：2006-07-15 00:00:00

  • Detection of donor-derived cells by polymerase chain reaction in neonatally tolerant mice. Microchimerism fails to predict tolerance.

    abstract：:Although it has long been appreciated that establishment of chimerism is important in the acquisition and maintenance of allograft tolerance, the importance of this relationship has been reemphasized recently. Using the exquisite sensitivity of the polymerase chain reaction we have studied qualitatively and quantitati...

    journal_title：Transplantation

    pub_type： 杂志文章

    doi：10.1097/00007890-199511270-00012

    authors： Alard P,Matriano JA,Socarras S,Ortega MA,Streilein JW

    更新日期：1995-11-27 00:00:00

  • Respiratory tract viral infections in bone marrow transplant patients.

    abstract：BACKGROUND:Community respiratory viruses such as respiratory syncytial virus (RSV), adenovirus, influenza A, influenza B, and the parainfluenza group are frequent causes of respiratory disease in bone marrow transplant (BMT) patients. MATERIAL AND METHODS:During the period from March 1993 to August 1999, 810 samples o...

    journal_title：Transplantation

    pub_type： 杂志文章

    doi：10.1097/01.TP.0000072012.26176.58

    authors： Raboni SM,Nogueira MB,Tsuchiya LR,Takahashi GA,Pereira LA,Pasquini R,Siqueira MM

    更新日期：2003-07-15 00:00:00

  • Human, nonhuman primate, and rat pancreatic islets express erythropoietin receptors.

    abstract：BACKGROUND:Erythropoietin (EPO) promotes survival in a variety of cells by mediating antiapoptotic signals through the EPO receptor (R). The authors examined pancreatic islets for the presence of EPO-R to determine whether these cells are protected by EPO from cytokine-induced apoptosis. METHODS:Reverse-transcriptase ...

    journal_title：Transplantation

    pub_type： 杂志文章

    doi：10.1097/01.TP.0000062862.88375.BD

    authors： Fenjves ES,Ochoa MS,Cabrera O,Mendez AJ,Kenyon NS,Inverardi L,Ricordi C

    更新日期：2003-04-27 00:00:00

  • Use of the methylxanthine derivative A802715 in transplantation immunology: I. Strong in vitro inhibitory effects on CD28-costimulated T cell activities.

    abstract：BACKGROUND:Recently, methylxanthines such as pentoxifylline (PTX) were shown to be immunosuppressive in vitro. Unfortunately, when used in transplant patients, PTX was poorly active as an immunosuppressant. Here we report that the new methylxanthine derivative A802715 not only is more active than PTX, it also suppresse...

    journal_title：Transplantation

    pub_type： 杂志文章

    doi：10.1097/00007890-199706270-00019

    authors： Lin Y,Goebels J,Rutgeerts O,Kasran A,Van Gool S,Ceuppens J,Schönharting M,Waer M

    更新日期：1997-06-27 00:00:00

  • Alloimmunization-activated suppressor cells. II. In vitro activity of suppressor cells implicated in the abrogation of lethal graft-versus-host reaction.

    abstract：:Incompatibility for DBA/2 (D2) minor histocompatibility antigens (MiHA) alone leads to a severe lethal graft-versus-host reaction (GVHR) in irradiated (D2 X B10.D2)F1 mice receiving a bone-marrow-plus-spleen-cell graft from B10.D2 donors. This mortality is abrogated when the donors are preimmunized simultaneously agai...

    journal_title：Transplantation

    pub_type： 杂志文章

    doi：10.1097/00007890-198309000-00016

    authors： Pritchard LL,Halle-Pannenko O

    更新日期：1983-09-01 00:00:00

  • Deficient T cell granulocyte-macrophage colony stimulating factor production in allogeneic bone marrow transplant recipients.

    abstract：:The proliferation and differentiation of donor hematopoietic progenitor cells in bone marrow transplantation (BMT) recipients is influenced by hematopoietic growth factors, which could derive from either T cells or adherent stromal bone marrow cells, or both. In this study of 20 BMT recipients, we asked whether T lymp...

    journal_title：Transplantation

    pub_type： 杂志文章

    doi：10.1097/00007890-199004000-00010

    authors： Thomas S,Clark SC,Rappeport JM,Nathan DG,Emerson SG

    更新日期：1990-04-01 00:00:00

  • Investigation of the potential use of immunosuppressive agent gliotoxin in organ transplantation.

    abstract：:Gliotoxin is an immunosuppressive secondary metabolite produced by several pathogenic fungi. It has previously been shown to prevent graft-versus-host disease in transplantation of allogeneic mouse bone marrow and to reduce the immunogenicity of human fetal pancreas. We here report on the effect of gliotoxin on the pr...

    journal_title：Transplantation

    pub_type： 杂志文章

    doi：

    authors： Sutton P,Moreland A,Hutchinson IV,Müllbacher A

    更新日期：1995-11-15 00:00:00

  • Bioequivalence of enteric-coated mycophenolate sodium and mycophenolate mofetil: a meta-analysis of three studies in stable renal transplant recipients.

    abstract：BACKGROUND:Mycophenolic acid (MPA) is an inhibitor of lymphocyte proliferation and is well established as an immunosuppressive agent in solid organ transplantation. The initial formulation of the drug was a prodrug formulation, mycophenolate mofetil (MMF, Cellcept), which is well absorbed and rapidly converted to mycop...

    journal_title：Transplantation

    pub_type： 杂志文章,meta分析

    doi：10.1097/01.tp.0000242137.68863.89

    authors： Johnston A,He X,Holt DW

    更新日期：2006-12-15 00:00:00

  • Bone marrow transplantation with T-cell-depleted grafts. I. Reconstitution of immunohemopoietic functions in lethally irradiated mice transplanted with unseparated or T-cell-depleted syngeneic bone marrow grafts.

    abstract：:The potential role of donor's mature T lymphocytes on the recovery of various immunological functions and hematopoiesis was investigated in lethally irradiated BALB/c mice by studying reconstitution with normal, as compared with T-cell-depleted, syngeneic marrow grafts. Recovery of total, as well as mononuclear, perip...

    journal_title：Transplantation

    pub_type： 杂志文章

    doi：

    authors： Shalit M,Ayalon M,Weiss L,Leshem B,Kedar E,Slavin S

    更新日期：1986-08-01 00:00:00

  • Should All Status 1A Patients Be Prioritized Over High MELD Patients? Concept of Risk Stratification in Extremely Ill Liver Transplant Recipients.

    abstract：BACKGROUND:Status 1A patients are prioritized over liver disease patients regardless of Model for End-stage Liver Disease (MELD) score. We aimed to identify groups with high waitlist mortality in Status 1A and MELD ≥40 patients to determine who would most benefit from transplantation. METHODS:Data on patients listed a...

    journal_title：Transplantation

    pub_type： 杂志文章

    doi：10.1097/TP.0000000000002651

    authors： Safwan M,Nwagu U,Collins K,Abouljoud M,Nagai S

    更新日期：2019-10-01 00:00:00

  • Alterations in chemokine receptor CCR5 expression on blood dendritic cells correlate with acute graft-versus-host disease.

    abstract：BACKGROUND:Dendritic cells (DC) are important in the development of acute graft-versus-host disease (GVHD) after allogeneic hemopoietic cell transplantation (alloHCT). The trafficking of immature DC from blood to GVHD target organs is likely to be regulated by chemokine receptors. METHODS:We performed flow cytometry t...

    journal_title：Transplantation

    pub_type： 杂志文章

    doi：10.1097/TP.0b013e31829e6d5b

    authors： Shahin K,Sartor M,Hart DN,Bradstock KF

    更新日期：2013-10-27 00:00:00

  • Successful deceased-donor kidney transplantation in crossmatch-positive patients with peritransplant plasma exchange and Rituximab.

    abstract：:Sensitized patients awaiting renal transplantation have a markedly reduced probability of receiving a crossmatch (XM)-negative renal allograft, and, even if transplanted with a negative complement-dependent cytotoxicity (CDC)-XM, they are at an increased risk of antibody-mediated humoral rejection with early graft los...

    journal_title：Transplantation

    pub_type： 杂志文章

    doi：10.1097/TP.0b013e318198a376

    authors： Beimler JH,Morath C,Schmidt J,Ovens J,Opelz G,Rahmel A,Zeier M,Süsal C

    更新日期：2009-03-15 00:00:00