Primary central nervous system malignant lymphoma in a patient with rheumatoid arthritis receiving low-dose methotrexate treatment.

Abstract:

:We report the first case of primary central nervous system lymphoma (PCNSL) developing in a patient with rheumatoid arthritis (RA) undergoing low-dose methotrexate therapy (LD-MTX). The characteristic clinical management and course in our experience of the present case illustrate the important points about PCNSL in methotrexate-associated lymphoproliferative disorders (MTX-LPD). The number of cases of MTX-LPD in RA patients may increase in the future, since current treatment strategies for RA recommend starting MTX use in early stage RA, and recent insights have tended to show an increase with higher doses.

journal_name

Br J Neurosurg

authors

Fukushima M,Katayama Y,Yokose N,Kura Y,Sawada U,Kotani A,Yoshino A

doi

10.3109/02688697.2013.798857

subject

Has Abstract

pub_date

2013-12-01 00:00:00

pages

824-6

issue

6

eissn

0268-8697

issn

1360-046X

journal_volume

27

pub_type

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