当前位置： SCI文献检索 > BIOORGANIC & MEDICINAL CHEMISTRY期刊下所有文献 > A quencher-free molecular beacon design based on pyrene excimer fluorescence using pyrene-labeled UNA (unlocked nucleic acid).

A quencher-free molecular beacon design based on pyrene excimer fluorescence using pyrene-labeled UNA (unlocked nucleic acid).

Abstract：

:A quencher-free molecular beacon capable of generating pyrene excimer fluorescence has been constructed using strategically positioned pyrene-UNA monomers. Hybridization of a fully complementary RNA target was accompanied by a pyrene excimer emission increase of more than 900%, and detection of RNA in living cells was demonstrated.

journal_name

Bioorg Med Chem

journal_title

Bioorganic & medicinal chemistry

authors

Karlsen KK,Okholm A,Kjems J,Wengel J

doi

10.1016/j.bmc.2013.04.062

subject

Has Abstract

pub_date

2013-10-15 00:00:00

pages

6186-90

issue

20

eissn

0968-0896

issn

1464-3391

pii

S0968-0896(13)00388-X

journal_volume

21

pub_type

杂志文章

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