Abstract:
:1. Using an optical method for measuring membrane potential, we have been able to monitor action-potential activity simultaneously in 14 neurons of the supraesophageal ganglion of the barnacle. 2. Under favorable conditions, 4-mV synaptic potentials could also be detected optically.
journal_name
J Neurophysioljournal_title
Journal of neurophysiologyauthors
Salzberg BM,Grinvald A,Cohen LB,Davila HV,Ross WNdoi
10.1152/jn.1977.40.6.1281subject
Has Abstractpub_date
1977-11-01 00:00:00pages
1281-91issue
6eissn
0022-3077issn
1522-1598journal_volume
40pub_type
杂志文章abstract::It is well established that patterns of sensory input can affect neuroplastic changes during early development. The scope and consequences of experience-dependent plasticity in the adult are less well understood. We studied the possibility that repeated exposure to trains of stroboscopic stimuli could induce a sensiti...
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abstract::The primary motor cortex (MI) commands motor output after kinematics are planned from goals, thought to occur in a larger premotor network. However, there is a growing body of evidence that MI is involved in processes beyond action generation, and neuronal subpopulations may perform computations related to cue-to-acti...
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abstract::The nucleus accumbens core (AcbC) is a striatal brain region essential for integrating motivated behavior and reward processing with premotor function. In humans and rodents, research has identified sex differences and sex steroid hormone sensitivity in AcbC-mediated behaviors, in disorders, and in rats in the electro...
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abstract::When a monkey attends to, remembers, and looks toward targets, the activity of some neurons in the lateral intraparietal area (LIP) changes. We recorded from isolated neurons during both a spatial and a shape match-to-sample task to examine and characterize voluntary active processes in LIP. Many LIP neurons show spat...
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abstract::Recent evidence has suggested that theta-frequency (4-7 Hz) oscillations around the human anterior cingulate cortex (ACC) and frontal cortex--that is, frontal midline theta (Fm theta) oscillations--may be involved in attentional processes in the brain. However, little is known about the physiological basis of Fm theta...
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journal_title:Journal of neurophysiology
pub_type: 杂志文章
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abstract::The relationship among neonatal seizures, abnormalities of the electroencephalogram (EEG), brain injury, and long-term neurological outcome (e.g., epilepsy) remains controversial. The effects of hypoxia alone (Ha) and hypoxia-ischemia (HI) were studied in neonatal rats at postnatal day 7; both models generate EEG seiz...
journal_title:Journal of neurophysiology
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abstract::We examined whether presenting an odor with a positive, neutral, or negative name would influence how people perceive it. In experiment 1, 40 participants rated 15 odors for their pleasantness, intensity, and arousal. In experiment 2, 30 participants passively smelled 10 odors while their skin conductance (SC), heart ...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00896.2007
更新日期:2008-01-01 00:00:00
abstract::The phasing of neuronal activity in a rhythmic motor network is determined by a neuron's intrinsic firing properties and synaptic inputs; these could vary in their relative importance under different modulatory conditions. In the lobster pyloric network, the firing of eight follower pyloric (PY) neurons is shaped by t...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00440.2005
更新日期:2005-11-01 00:00:00
abstract::1. The little brown bat, Myotis lucifugus, employs biosonar pulses containing broadband frequency-modulated (FM) sounds of only one harmonic during the initial phases of echolocation. Neurons throughout the auditory cortex exhibit delay-dependent facilitation to artificial pulses and echoes at particular echo delays. ...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
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abstract::Spontaneous and stimulus-evoked excitatory postsynaptic currents (EPSCs) were recorded in calyx nerve terminals from the turtle vestibular lagena to quantify key attributes of quantal transmission at this synapse. On average, EPSC events had a magnitude of ∼ 42 pA, a rise time constant of τ(0) ∼ 229 μs, decayed to bas...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00055.2015
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abstract::The dorsal nucleus of the lateral lemniscus (DNLL) receives afferent inputs from many brain stem nuclei and, in turn, is a major source of inhibitory inputs to the inferior colliculus (IC). The goal of this study was to characterize the monaural and binaural response properties of neurons in the DNLL of unanesthetized...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00451.2007
更新日期:2007-09-01 00:00:00
abstract::1. There is a long-standing debate about whether the large spiny cells in the hilar region of the hippocampus should be classified as pyramidal cells of Ammon's horn or as a distinct cell type of the dentate gyrus. The rationale for grouping these hilar neurons (termed "mossy cells") with pyramidal cells of Ammon's ho...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.1993.70.4.1281
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abstract::In this article, we review a recent paper by Stevenson et al. (J Neurosci 34: 691-697, 2014). This paper illustrates the need to present different forms of stimuli in order to characterize the perceptual abilities of people with autism spectrum disorder (ASD). Furthermore, we will discuss their behavioral results and ...
journal_title:Journal of neurophysiology
pub_type: 评论,杂志文章
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更新日期:2014-12-01 00:00:00
abstract::1. The extracellular activity of 45 antidromically identified spinocervical tract (SCT) neurons responsive to light mechanical stimulation of the glabrous surfaces of the forepaw was examined in raccoons anesthetized with pentobarbital sodium. An additional seven neurons had peripheral receptive fields (RFs) located o...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.1989.61.1.138
更新日期:1989-01-01 00:00:00
abstract::Individuals who have experienced a stroke often demonstrate inappropriate muscle activity phasing in the paretic leg during locomotion. Past research has demonstrated that inappropriate paretic phasing varies between behavioral contexts and is reduced during unilateral pedaling with the nonparetic leg inactive. We inv...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00256.2017
更新日期:2018-06-01 00:00:00
abstract::The mechanisms underlying the depression of evoked fast excitatory postsynaptic currents (EPSCs) following superfusion with medium deprived of oxygen and glucose (in vitro ischemia) for a 4-min period in hippocampal CA1 neurons were investigated in rat brain slices. The amplitude of evoked fast EPSCs decreased by 85 +...
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abstract::We have previously shown that sinusoidal galvanic vestibular stimulation (sGVS), delivered at 0.2-2.0 Hz, evokes a partial entrainment of muscle sympathetic nerve activity (MSNA). Moreover, at lower frequencies of stimulation (0.08-0.18 Hz) sGVS produces two peaks of modulation: one (primary) peak associated with the ...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00679.2018
更新日期:2019-05-01 00:00:00
abstract::Cortical neurons display two fundamental nonlinear response characteristics: contrast-set gain control (also termed contrast normalization) and response expansion (also termed half-squaring). These nonlinearities could play an important role in forming and maintaining stimulus selectivity during natural viewing, but o...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.2002.88.2.888
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abstract::The corticotectal influences of somatosensory cortex were investigated by using reversible deactivation of cortex by cooling. More than half of the somatosensory superior colliculus (SC) cells studied exhibited a response depression (often not apparent qualitatively) or an elimination of responses to somatosensory sti...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.1986.55.6.1352
更新日期:1986-06-01 00:00:00
abstract::GABAergic interneurons in the hippocampus express high levels of alpha7 nicotinic acetylcholine receptors, but because of the diverse roles played by hippocampal interneurons, the impact of activation of these receptors on hippocampal output neurons (i.e., CA1 pyramidal cells) is unclear. Activation of hippocampal int...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00316.2001
更新日期:2002-01-01 00:00:00
abstract::Responses of low characteristic-frequency (CF) neurons in the inferior colliculus were obtained to amplitude-modulated (AM) high-frequency tones in which the modulation rate was equal to the neuron's CF. Despite all spectral components lying outside the pure tone-evoked response areas, discharge rates were modulated b...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00034.2004
更新日期:2004-09-01 00:00:00
abstract::1. Outward currents in identified cell types from the pyloric system of the stomatogastric ganglion (STG) of the spiny lobster, Panulirus marginatus, were studied under two-microelectrode voltage clamp. A comparison was made between data from intact cells and somata isolated by ligation of the primary neurite of these...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.1993.69.6.2056
更新日期:1993-06-01 00:00:00
abstract::In this study we present further evidence supporting the reciprocal nature of output effects on forearm flexor and extensor muscles from single corticomotoneuronal (CM) cells. Spike-triggered averaging of rectified EMG activity was used to test the output effects of 105 motor cortex cells in two rhesus monkeys (Macaca...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.1985.53.4.959
更新日期:1985-04-01 00:00:00
abstract::cAMP-dependent protein kinase (PKA) and protein kinase C (PKC) are two major modulators of synaptic transmission in the CNS but little is known about how they affect synaptic transmission in the human CNS. In this study, we used forskolin, a PKA activator, and phorbol ester, a PKC activator, to examine the effects of ...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.01031.2002
更新日期:2003-05-01 00:00:00
abstract::1. Buffering of glutamate-induced Ca2+ loads in single rat hippocampal neurons grown in primary culture was studied with ratiometric fluorescent Ca2+ indicators. The hypothesis that mitochondria buffer the large Ca2+ loads elicited by glutamate was tested. 2. The relationship between glutamate concentration and the re...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.1996.76.3.1611
更新日期:1996-09-01 00:00:00
abstract::Visual object information is conveyed from V1 to area TE along the ventral visual pathway with increasing receptive field (RF) sizes. The RFs of TE neurons are known to be large, but it is largely unknown how large RFs are shaped along the ventral visual pathway. In this study, we addressed this question in two aspect...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00348.2017
更新日期:2017-10-01 00:00:00
abstract::Upon prolonged viewing of a sinusoidal grating, the visual system is selectively desensitized to the spatial frequency of the grating, while the sensitivity to other spatial frequencies remains largely unaffected. This technique, known as pattern adaptation, has been so central to the psychophysical study of the mecha...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00216.2009
更新日期:2009-10-01 00:00:00