Effect of shunt surgery on spleen size, portal pressure and oesophageal varices in patients with non-cirrhotic portal hypertension.

abstract：BACKGROUND AND AIMS:The classification of gastritis by using the revised Sydney system suggests that there are two types of Helicobacter pylori-related gastritis. The aim of the present study was to examine the risk factors that might be involved in the presence of either atrophic gastritis or intestinal metaplasia of ...

journal_title：Journal of gastroenterology and hepatology

authors： Tsukui T,Kashiwagi R,Sakane M,Tabata F,Akamatsu T,Wada K,Futagami S,Miyake K,Sueoka N,Hirakawa T,Kobayashi M,Fujimori T,Sakamoto C

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND AND AIM:The goals of the study were to identify an effective treatment for ascites and to examine the influence of tolvaptan on outcomes by investigating non-responders to tolvaptan and comparing outcomes of hepatic cirrhosis in patients treated with and without tolvaptan. METHODS:In Study 1, of 145 patient...

journal_title：Journal of gastroenterology and hepatology

authors： Iwamoto T,Maeda M,Saeki I,Hidaka I,Tajima K,Ishikawa T,Takami T,Sakaida I

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND AND AIM:Data about the efficacy of de novo combination therapies, or optimization strategy by adding the other drug based on the virological response at week 24 of low genetic barrier antiviral agents is still limited. This study aimed to compare the efficacy at week 104 of lamivudine monotherapy (MONO), lam...

journal_title：Journal of gastroenterology and hepatology

authors： Liang X,Cheng J,Sun Y,Chen X,Li T,Wang H,Jiang J,Chen X,Long H,Tang H,Yu Y,Sheng J,Chen S,Niu J,Ren H,Shi J,Dou X,Wan M,Jiang J,Xie Q,Shi G,Ning Q,Chen C,Tan D,Ma H,Sun J,Jia J,Zhuang H,Hou J

更新日期：2015-04-01 00:00:00

abstract：BACKGROUND:A nitroxide radical, 4-hydroxyl-2,2,6,6-tetramethylpiperidin-1-oxyl (TEMPOL), is directly reduced to hydroxylamine by ascorbic acid (AsA). Ascorbic acid is oxidized to dehydroascorbic acid (DHA) by ascorbic acid oxidase (AAOx), and DHA is reduced to AsA by glutathione (GSH). In the present study, in vivo and...

journal_title：Journal of gastroenterology and hepatology

authors： Tada M,Yokoyama H,Ito O,Ohya H,Ogata T

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND AND AIMS:The immunogenetic basis of autoimmune diseases has become more and more evident. We have analyzed the human leukocyte antigen (HLA) associations with type-1 autoimmune hepatitis (AIH) among patients from western India. METHODS:In 20 patients and 120 healthy controls, polymerase chain reaction ampli...

journal_title：Journal of gastroenterology and hepatology

authors： Shankarkumar U,Amarapurkar DN,Kankonkar S

更新日期：2005-02-01 00:00:00

abstract：BACKGROUND AND AIM:Non-invasive markers are essential to assess the progression of chronic liver diseases to fibrosis/ cirrhosis and the effectiveness of therapeutic strategies. The aim of this study was to evaluate the ability of non-invasive markers to identify significant fibrosis, severe fibrosis, and cirrhosis in ...

journal_title：Journal of gastroenterology and hepatology

authors： Sheptulina A,Shirokova E,Nekrasova T,Blum H,Ivashkin V

更新日期：2016-12-01 00:00:00

abstract：BACKGROUND AND AIM:Fucosylated alpha-fetoprotein (AFP-L3) is known to be a marker of poor prognosis in patients with hepatocellular carcinoma (HCC). However, it has been difficult to measure AFP-L3 under low AFP (≤ 20 ng/mL). The aim of this study was to elucidate the role of AFP-L3 in HCC patients with low AFP conditi...

journal_title：Journal of gastroenterology and hepatology

authors： Nouso K,Kobayashi Y,Nakamura S,Kobayashi S,Takayama H,Toshimori J,Kuwaki K,Hagihara H,Onishi H,Miyake Y,Ikeda F,Shiraha H,Takaki A,Iwasaki Y,Kobashi H,Yamamoto K

更新日期：2011-07-01 00:00:00

abstract：:Helicobacter pylori infection may not be the primary cause of duodenal ulceration in cases not associated with non-steroidal anti-inflammatory drugs, but may be a secondary complication. In developing countries with a uniformly high prevalence of H. pylori infection there are marked regional differences in the prevale...

journal_title：Journal of gastroenterology and hepatology

authors： Tovey FI,Hobsley M

更新日期：1999-11-01 00:00:00

abstract：:Complete duplication of the entire large bowel with partial ileal involvement is very rare and diagnosis can often be difficult as illustrated by this case report. We also review the other clinical associations of this rare condition and briefly discuss the embryology of duplications of the gastrointestinal tract. ...

journal_title：Journal of gastroenterology and hepatology

authors： Jimenez SG,Oliver MR,Stokes KB,Morreau PN,Chow CW

更新日期：1999-09-01 00:00:00

abstract：BACKGROUND:Patients with cirrhosis exhibit splanchnic, peripheral and pulmonary vasodilation, which are thought to play a role in increasing portal pressure, promoting sodium retention and determining arterial hypoxaemia. The present study investigated whether these abnormalities are influenced by portal hypertension o...

journal_title：Journal of gastroenterology and hepatology

authors： Luca A,García-Pagán JC,de Lacy AM,Escorsell A,Feu F,Visa J,Bosch J,Rodés J

更新日期：1999-11-01 00:00:00

abstract：BACKGROUND AND AIMS:Uncoupling protein-2 (UCP-2) is a negative regulator of reactive oxygen species (ROS) production. We investigated the effect of UCP-2 on disease progression in a murine dextran sodium sulfate (DSS)-induced colitis model, and the expression and distribution of tight junction (TJ) proteins, such as oc...

journal_title：Journal of gastroenterology and hepatology

authors： Zhang H,Kuai XY,Yu P,Lin L,Shi R

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND:Sodium chloride (NaCl) is a strong promoter of gastric cancer. We hypothesized that inducible nitric oxide synthase (iNOS) induced by NaCl may be involved in its promoting effects. We investigated iNOS expression by hypertonic NaCl solutions and its pathophysiological roles in the gastric mucosa of rats and ...

journal_title：Journal of gastroenterology and hepatology

authors： Tatemichi M,Ogura T,Sakurazawa N,Nagata H,Sugita M,Esumi H

更新日期：2003-09-01 00:00:00

abstract：:To identify the preneoplastic lesions of hepatocellular carcinoma and the fine structure of preneoplastic hepatocytes, we studied proliferative conditions in cirrhosis of the liver. In all, 46 foci of cellular alteration (FCA), three regions of adenomatous hyperplasia (ADH), and 21 small hepatocellular carcinomas (sHC...

journal_title：Journal of gastroenterology and hepatology

authors： Seki S,Sakaguchi H,Kawakita N,Yanai A,Tamori A,Yabusako T,Nishiguchi S,Kuroki T,Kobayashi K,Monna T

更新日期：1993-11-01 00:00:00

abstract：BACKGROUND AND AIM:Studies have shown monounsaturated oleic acid to be less toxic than palmitic acid and to prevent/attenuate palmitic acid hepatocites toxicity in steatosis models in vitro. However, to what degree these effects are mediated by steatosis extent is unknown. METHODS:We evaluated whether steatosis per se...

journal_title：Journal of gastroenterology and hepatology

authors： Ricchi M,Odoardi MR,Carulli L,Anzivino C,Ballestri S,Pinetti A,Fantoni LI,Marra F,Bertolotti M,Banni S,Lonardo A,Carulli N,Loria P

更新日期：2009-05-01 00:00:00

abstract：BACKGROUND AND AIM:Early life exposure to the famine may affect the susceptibility to the metabolic disorders. The objective of this study was to examine the associations of early life exposure to the Chinese Famine (1959-1961) with the risk of fatty liver disease, obesity, hypertension, and hyperglycemia in adulthood....

journal_title：Journal of gastroenterology and hepatology

authors： Chen JP,Peng B,Tang L,Sun R,Hu S,Wen XY,Que P,Wang YH

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND AND AIM:Numerous mutations of bilirubin uridine diphosphate-glucuronosyltransferase gene (UGT1A1) have been reported in patients with familial unconjugated hyperbilirubinemia. The UGT1A1 mutation appears to be considerably different among ethnic groups. To clarify the incidence of this gene mutation in the J...

journal_title：Journal of gastroenterology and hepatology

authors： Takeuchi K,Kobayashi Y,Tamaki S,Ishihara T,Maruo Y,Araki J,Mifuji R,Itani T,Kuroda M,Sato H,Kaito M,Adachi Y

更新日期：2004-09-01 00:00:00

abstract：:The production of interleukin-8 (CINC: cytokine-induced neutrophil chemo-attractant) from different cell populations in the rat liver was studied and cells related to the initiation of CINC production in lipopolysaccharide (LPS)-injected endotoxaemic rats were characterized. Sinusoidal endothelial cells (16.4 +/- 10.6...

journal_title：Journal of gastroenterology and hepatology

authors： Ohkubo K,Masumoto T,Horiike N,Onji M

更新日期：1998-07-01 00:00:00

abstract：:Biliary strictures can be categorized according to technical factor as anastomotic or nonanastomotic strictures. Biliary anastomotic stricture is a common complication after living-donor liver transplantation, occasionally causing deaths. The two most commonly used methods for biliary anastomosis are duct-to-duct anas...

journal_title：Journal of gastroenterology and hepatology

authors： Chok KS,Lo CM

更新日期：2014-10-01 00:00:00

abstract：:The main purpose of the present study was to demonstrate the incidence of Paneth cells in colorectal tubular adenomas of Japanese descendants in Hawaii. Paneth cells were found in 73 of 322 adenomas (22.7%) of Japanese descendants in Hawaii. The incidence of Paneth cells in adenomas located from the caecum to the tran...

journal_title：Journal of gastroenterology and hepatology

authors： Wada R,Kuwabara N,Suda K

更新日期：1994-05-01 00:00:00

abstract：BACKGROUND AND AIM:Hepatitis B core-related antigen (HBcrAg) has been shown to correlate with various viral markers in chronic hepatitis B, but its role in defining natural history is not well studied. We aimed to investigate the use of HBcrAg to define different phases of chronic hepatitis B. METHODS:Stored residual ...

journal_title：Journal of gastroenterology and hepatology

authors： Chan HLY,Yasuda S,Wong GLH,Tada T,Chan CKM,Kumada T,Tse YK,Wong VWS,Toyoda H

更新日期：2020-04-15 00:00:00

abstract：BACKGROUND:The purpose of this study was to determine the potential role of three-dimensional (3-D) conformal radiotherapy (RT) in treatment of unresectable hepatocellular carcinoma (HCC). METHODS:Thirteen patients were included in this study, which was conducted between 1993 and 1996. Nine patients (group A) were tre...

journal_title：Journal of gastroenterology and hepatology

authors： Cheng SH,Lin YM,Chuang VP,Yang PS,Cheng JC,Huang AT,Sung JL

更新日期：1999-10-01 00:00:00

abstract：BACKGROUND AND AIM:Disease activity and severity of ulcerative colitis (UC) is assessed using colonoscopy, which is invasive, costly and has poor patient acceptability. The role of non-invasive biomarkers of intestinal inflammation in the evaluation of patients with UC is not known. The aim of the study was to examine ...

journal_title：Journal of gastroenterology and hepatology

authors： Masoodi I,Kochhar R,Dutta U,Vaishnavi C,Prasad KK,Vaiphei K,Kaur S,Singh K

更新日期：2009-11-01 00:00:00

abstract：BACKGROUND AND AIM:Nonalcoholic steatohepatitis (NASH) is a metabolic disorder of the liver that may evolve into fibrosis or cirrhosis. Recent studies have shown reduction of experimental liver fibrosis with the use of angiotensin-converting-enzyme inhibitors or angiotensin-receptor antagonists. The aim of this study w...

journal_title：Journal of gastroenterology and hepatology

authors： Ibañez P,Solis N,Pizarro M,Aguayo G,Duarte I,Miquel JF,Accatino L,Arrese M

更新日期：2007-06-01 00:00:00

abstract：BACKGROUND AND AIMS:Cancer invasion and metastasis are critical events for patient prognosis; however, the most important step in the whole process of lymph node (LN) metastasis in gastric cancer remains obscure. In this study, the significance of cancer cell behaviors, such as cell detachment, stromal invasion and lym...

journal_title：Journal of gastroenterology and hepatology

authors： Kamata I,Ishikawa Y,Akishima-Fukasawa Y,Ito K,Akasaka Y,Uzuki M,Fujimoto A,Morita H,Tamai S,Maehara T,Ogata K,Shimokawa R,Igarashi Y,Miki K,Ishii T

更新日期：2009-09-01 00:00:00

abstract：BACKGROUND AND AIM:Patients with non-alcoholic fatty liver disease (NAFLD) have an increased risk of atherosclerosis and alanine aminotransferase (ALT) is associated with insulin resistance independently of metabolic factors. The aim of the present study was to investigate whether NAFLD patients with ALT elevation had ...

journal_title：Journal of gastroenterology and hepatology

authors： Wang CC,Lin SK,Tseng YF,Hsu CS,Tseng TC,Lin HH,Wang LY,Kao JH

更新日期：2009-08-01 00:00:00

abstract：BACKGROUND AND AIM:Tobacco smoking is a risk factor for gastrointestinal disorders, causing mucosal damage and impairing immune responses. However, smoking has been found to be protective against ulcerative colitis (UC). Human leukocyte antigen (HLA) is a major susceptibility locus for UC, and HLA-DRB1*15:02 has the st...

journal_title：Journal of gastroenterology and hepatology

authors： Lee HS,Kim K,Jung S,Hong M,Kim BM,Yoo DS,Moon JW,Baek J,Hwang SW,Park SH,Yang SK,Han B,Song K,Ye BD

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND AND AIM:This study investigated whether diabetes mellitus (DM) increased the risk of pancreatic cancer and whether anti-diabetic drugs reduced the risk in Taiwan. METHODS:We designed a population-based cohort study using the Taiwan National Health Insurance Database, which consisted of 49,803 patients aged ...

journal_title：Journal of gastroenterology and hepatology

authors： Liao KF,Lai SW,Li CI,Chen WC

更新日期：2012-04-01 00:00:00

abstract：BACKGROUND AND AIM:Ecabet sodium is reported to have a bactericidal effect on Helicobacter pylori and inhibit urease activity in vitro. METHODS:Seven male volunteers (mean age, 51.3 years; range, 45-55 years) with H. pylori infection were medicated with 1 g ecabet sodium t.i.d. for 4 weeks. The urea breath test (UBT) ...

journal_title：Journal of gastroenterology and hepatology

authors： Okuda M,Yamamoto N,Fukuda N,Maekawa K,Kusaka T,Hashimoto M,Kotake J,Koizuka H,Fukuda Y

更新日期：2012-04-01 00:00:00

abstract：BACKGROUND AND AIM:The introduction of sofosbuvir has revolutionized the treatment of chronic hepatitis C. This study was planned to observe whether the efficacy and tolerability of sofosbuvir-based regimens demonstrated in phase 3 clinical trial results translate into real-life clinical practice. METHODS:This prospec...

journal_title：Journal of gastroenterology and hepatology

authors： Sood A,Midha V,Mahajan R,Narang V,Mehta V,Wander P,Sharma S,Kaur K,Singh D

更新日期：2017-04-01 00:00:00

abstract：BACKGROUND:Studies of eradication of Helicobacter pylori and subsequent resolution of H. pylori-related gastritis, have focused mainly on medium and long-term change following eradication therapies. Results from those studies have shown that both acute and chronic inflammatory changes found in gastric mucosa eventually...

journal_title：Journal of gastroenterology and hepatology

authors： Chen W,Shu D,Wilson IR,Tie A,Chadwick VS

更新日期：1999-04-01 00:00:00