Use of hepatitis B virus core-related antigen to evaluate natural history of chronic hepatitis B.

abstract：BACKGROUND:We designed an animal model in order to clarify whether Helicobacter pylori infection causes the gastric mucosal lesion frequently seen in cirrhotic patients. METHODS:Ammonia (NH3) solution was given to rats with carbon tetrachloride-induced cirrhosis. The gastric mucosal hexosamine (Hx) content and histopa...

journal_title：Journal of gastroenterology and hepatology

authors： Sugimoto M,Machida Y,Ito K

更新日期：1999-06-01 00:00:00

abstract：BACKGROUND:To elucidate the incidence of the rare cases of icteric type hepatocellular carcinoma (IHCC), we conducted a retrospective study. The clinical outcomes of IHCC cases were also analyzed. METHODS:From January 1986 to December 1997, newly diagnosed HCC cases were evaluated and reviewed from an admission regist...

journal_title：Journal of gastroenterology and hepatology

authors： Huang JF,Wang LY,Lin ZY,Chen SC,Hsieh MY,Chuang WL,Yu MY,Lu SN,Wang JH,Yeung KW,Chang WY

更新日期：2002-02-01 00:00:00

abstract：BACKGROUND AND AIM:Abdominal wall hernia is a common feature of decompensated liver cirrhosis and frequently causes life-threatening complications or severe pain. However, there have been no data reported on postoperative mortality, hepatic functional deterioration and recurrence rate according to Child-Turcotte-Pugh (...

journal_title：Journal of gastroenterology and hepatology

authors： Park JK,Lee SH,Yoon WJ,Lee JK,Park SC,Park BJ,Jung YJ,Kim BG,Yoon JH,Kim CY,Ha J,Park KJ,Kim YJ

更新日期：2007-03-01 00:00:00

abstract：BACKGROUND AND AIM:We previously discovered that tumor suppressor candidate 3 (TUSC3) was overexpressed and predicted worse prognosis in colon cancer patients. However, the mechanisms of upregulation of TUSC3 in colon cancer remained unclear. METHODS:MiR-873-5p was predicted and identified as the regulator of TUSC3 vi...

journal_title：Journal of gastroenterology and hepatology

authors： Zhu Y,Zhang X,Qi M,Zhang Y,Ding F

更新日期：2019-12-01 00:00:00

abstract：:Although the advancement of molecular oncology in gastric cancer lags behind that of colorectal cancer, the rapid developments witnessed in recent years have improved our understanding of the carcinogenesis, aetiology, progression and metastasis of gastric cancer. The different molecular genetic alterations in intesti...

journal_title：Journal of gastroenterology and hepatology

authors： Chan AO,Luk JM,Hui WM,Lam SK

更新日期：1999-12-01 00:00:00

abstract：BACKGROUND AND AIM:To investigate the relationship between human leptin receptor (LEPR) gene G3057A polymorphism and type 2 diabetes mellitus (T2DM) patients complicated with or without non-alcoholic fatty liver disease (NAFLD). METHODS:Two hundred and sixteen cases of newly diagnosed T2DM patients (104 cases complica...

journal_title：Journal of gastroenterology and hepatology

authors： Lu H,Sun J,Sun L,Shu X,Xu Y,Xie D

更新日期：2009-02-01 00:00:00

abstract：BACKGROUND:The reasons for the viral persistence of hepatitis B virus infection (HBV) are unknown, but are probably related to host immune factors. Cytokines play a significant role in immune defense. The present study was undertaken to investigate the association between HBV infection and polymorphisms of tumor necros...

journal_title：Journal of gastroenterology and hepatology

authors： Cheong JY,Cho SW,Hwang IL,Yoon SK,Lee JH,Park CS,Lee JE,Hahm KB,Kim JH

更新日期：2006-07-01 00:00:00

abstract：:We have previously established a cell damage model, with damage induced by either acid or pepsin treatment for 30 min, involving a rat gastric epithelial cell line (RGM1). In the present study, pretreatment of cells with epidermal growth factor (EGF; 0.1-10 ng/mL) or sucralfate (0.1-3 mg/mL) for 4 h prevented such cel...

journal_title：Journal of gastroenterology and hepatology

authors： Furukawa O,Okabe S

更新日期：1997-05-01 00:00:00

abstract：BACKGROUND AND AIM:As bacterial resistance to clarithromycin limits the efficacy of clarithromycin-based regimens for Helicobacter pylori infection, attention has turned to quinolone-based rescue therapies. Resistance of H. pylori to both clarithromycin and quinolone can be predicted by genetic testing. Here, we used t...

journal_title：Journal of gastroenterology and hepatology

authors： Yamade M,Sugimoto M,Uotani T,Nishino M,Kodaira C,Furuta T

更新日期：2011-09-01 00:00:00

abstract：BACKGROUND:Helicobacter pylori causes chronic gastritis, peptic ulcer, gastric cancer and mucosa-associated lymphoid tissue (MALT) lymphoma. Different genotypes of H. pylori are confirmed from diverse geographical areas. Its association with clinical diseases remains controversial. The aim of the present study was to i...

journal_title：Journal of gastroenterology and hepatology

authors： Perng CL,Lin HJ,Sun IC,Tseng GY,Facg

更新日期：2003-11-01 00:00:00

abstract：BACKGROUND:Microbial agents are a possible cause of ulcerative colitis. We have previously reported evidence of bacteria invading the colonic mucosa of patients with ulcerative colitis. We have isolated bacteria from inflamed colonic mucosa, examined the localization of the species in the mucosa, and assayed for serum ...

journal_title：Journal of gastroenterology and hepatology

authors： Ohkusa T,Sato N,Ogihara T,Morita K,Ogawa M,Okayasu I

更新日期：2002-08-01 00:00:00

abstract：BACKGROUND AND AIM:Lipids play important roles in inflammation and may be involved in the pathophysiology of inflammatory bowel disease (IBD). Here, we evaluated the characteristics of the plasma lipid profile in patients with IBD. METHODS:Plasma samples were collected from 20 patients with Crohn's disease (CD), 20 pa...

journal_title：Journal of gastroenterology and hepatology

authors： Iwatani S,Iijima H,Otake Y,Amano T,Tani M,Yoshihara T,Tashiro T,Tsujii Y,Inoue T,Hayashi Y,Takeda K,Hayashi A,Fujita S,Shinzaki S,Takehara T

更新日期：2020-08-01 00:00:00

abstract：INTRODUCTION:Endoscopic obliteration of esophageal varices by endoscopic variceal ligation (EVL) is an effective form of secondary prophylaxis. However, there is no consensus regarding the technical aspects of EVL for secondary prophylaxis. The present study compares the technical aspects of EVL (frequency of sessions,...

journal_title：Journal of gastroenterology and hepatology

authors： Harewood GC,Baron TH,Song LM

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND AND AIM:Non-invasive markers are essential to assess the progression of chronic liver diseases to fibrosis/ cirrhosis and the effectiveness of therapeutic strategies. The aim of this study was to evaluate the ability of non-invasive markers to identify significant fibrosis, severe fibrosis, and cirrhosis in ...

journal_title：Journal of gastroenterology and hepatology

authors： Sheptulina A,Shirokova E,Nekrasova T,Blum H,Ivashkin V

更新日期：2016-12-01 00:00:00

abstract：:Capsules (8 x 30 mm) of technetium-99m pertechnetate were designed for measurement of portal blood flow. Most of the radionuclide entered the superior mesenteric vein. The capsule was taken orally and monitored with a collimator for scintigraphy until it reached the small intestine, when a magnetic field completed an ...

journal_title：Journal of gastroenterology and hepatology

authors： Shiomi S,Kuroki T,Ueda T,Nishiguchi S,Nakajima S,Kobayashi K,Kurai O,Ikeoka N,Monna T,Ochi H

更新日期：1990-05-01 00:00:00

abstract：BACKGROUND AND AIM:Fucosylated alpha-fetoprotein (AFP-L3) is known to be a marker of poor prognosis in patients with hepatocellular carcinoma (HCC). However, it has been difficult to measure AFP-L3 under low AFP (≤ 20 ng/mL). The aim of this study was to elucidate the role of AFP-L3 in HCC patients with low AFP conditi...

journal_title：Journal of gastroenterology and hepatology

authors： Nouso K,Kobayashi Y,Nakamura S,Kobayashi S,Takayama H,Toshimori J,Kuwaki K,Hagihara H,Onishi H,Miyake Y,Ikeda F,Shiraha H,Takaki A,Iwasaki Y,Kobashi H,Yamamoto K

更新日期：2011-07-01 00:00:00

abstract：:The approach of a pediatric hepatologist in managing children with hepatitis C virus (HCV) differs from adult practice, because the pediatric hepatologist is dealing with the beginning of a chronic illness in which long-term outcomes will not occur for 20 or 40 years, and it is not possible to predict in the early sta...

journal_title：Journal of gastroenterology and hepatology

authors： Hardikar W

更新日期：2002-04-01 00:00:00

abstract：BACKGROUND:Infection with hepatitis E virus (HEV) is a major cause of acute viral hepatitis in several developing countries. Although usually self-limiting and benign, the disease is particularly severe among pregnant women, with mortality rates reaching 15-20%. METHODS:Immune parameters among pregnant women with acut...

journal_title：Journal of gastroenterology and hepatology

authors： Pal R,Aggarwal R,Naik SR,Das V,Das S,Naik S

更新日期：2005-07-01 00:00:00

abstract：BACKGROUND AND AIMS:There is a paucity of literature regarding the clinical profile of chronic pancreatitis (CP) in children. The aims of this retrospective study were to determine the etiology and clinical presentation, and to present our experience in diagnosing CP in children in China. METHODS:Clinical data of chil...

journal_title：Journal of gastroenterology and hepatology

authors： Wang W,Liao Z,Li ZS,Shi XG,Wang LW,Liu F,Wu RP,Zheng JM

更新日期：2009-12-01 00:00:00

abstract：BACKGROUND AND AIM:Endoscopic ultrasound-guided fine-needle biopsy (EUS-FNB) is used to diagnose lesions within or adjacent to the digestive tract. However, there is no report on the overall diagnostic accuracy, technical success, and adverse events of FNB. The aims of this study were to conduct a systematic review and...

journal_title：Journal of gastroenterology and hepatology

authors： Li DF,Wang JY,Yang MF,Xiong F,Zhang DG,Xu ZL,Luo MH,Jing ZD,Wang KX,Wang LS,Yao J

更新日期：2020-08-01 00:00:00

abstract：:AL amyloidosis complicating multiple myeloma is rare but well recognized. Endoscopic appearances of amyloid in the gastrointestinal tract can, however, be highly variable. Macroscopic appearances of the duodenum can range from scalloping (often seen in celiac disease) to that of duodenitis; erosive disease, frank ulce...

journal_title：Journal of gastroenterology and hepatology

authors： Hurlstone DP

更新日期：2002-05-01 00:00:00

abstract：BACKGROUND AND AIMS:Changes in neutrophil functions in obstructive jaundice have been poorly understood. An in vitro experimental study was performed to evaluate the effect of obstructive jaundice on the functions of macrophages (secretion of neutrophil chemoattractants) and neutrophils (chemotaxis and superoxide anion...

journal_title：Journal of gastroenterology and hepatology

authors： Tsuji K,Kubota Y,Yamamoto S,Yanagitani K,Amoh Y,Takaoka M,Ogura M,Kin H,Inoue K

更新日期：1999-05-01 00:00:00

abstract：BACKGROUND AND AIMS:According to reports in Japanese patients, 1 week of Helicobacter pylori eradication therapy alone is not adequate for healing of gastric ulcers; 7-8 weeks of anti-ulcer therapy are subsequently required. We compared a gastroprotective drug, sofalcone, and an H(2)-receptor antagonist, cimetidine, in...

journal_title：Journal of gastroenterology and hepatology

authors： Higuchi K,Watanabe T,Tanigawa T,Tominaga K,Fujiwara Y,Arakawa T

更新日期：2010-05-01 00:00:00

abstract：:Primary liver cancer, particularly hepatocellular carcinoma (HCC) remains a significant disease worldwide. It is among the top three causes of cancer death in the Asia Pacific region because of the high prevalence of its main etiological agents, chronic hepatitis B virus (HBV) and hepatitis C virus (HCV) infections. I...

journal_title：Journal of gastroenterology and hepatology

authors： Yuen MF,Hou JL,Chutaputti A,Asia Pacific Working Party on Prevention of Hepatocellular Carcinoma.

更新日期：2009-03-01 00:00:00

abstract：BACKGROUND AND AIM:Endoscopic assessment of mucosal healing in ulcerative colitis (UC) is increasingly accepted as a measure of disease activity, therapeutic goal, and the key prognostic indicator. While regular endoscopy evaluates appearance of the mucosal surface, confocal laser endomicroscopy (CLE) enables in vivo v...

journal_title：Journal of gastroenterology and hepatology

authors： Macé V,Ahluwalia A,Coron E,Le Rhun M,Boureille A,Bossard C,Mosnier JF,Matysiak-Budnik T,Tarnawski AS

更新日期：2015-03-01 00:00:00

abstract：BACKGROUND AND AIM:Ecabet sodium is reported to have a bactericidal effect on Helicobacter pylori and inhibit urease activity in vitro. METHODS:Seven male volunteers (mean age, 51.3 years; range, 45-55 years) with H. pylori infection were medicated with 1 g ecabet sodium t.i.d. for 4 weeks. The urea breath test (UBT) ...

journal_title：Journal of gastroenterology and hepatology

authors： Okuda M,Yamamoto N,Fukuda N,Maekawa K,Kusaka T,Hashimoto M,Kotake J,Koizuka H,Fukuda Y

更新日期：2012-04-01 00:00:00

abstract：BACKGROUND AND AIM:Intestinal failure (IF) is a rare but devastating complication of Crohn's disease (CD). The clinical and surgical factors that predispose to IF are poorly understood. The aim of this study was to define clinical factors that predispose to IF. METHODS:A retrospective case-control study was performed ...

journal_title：Journal of gastroenterology and hepatology

authors： Gearry RB,Kamm MA,Hart AL,Bassett P,Gabe SM,Nightingale JM

更新日期：2013-05-01 00:00:00

abstract：BACKGROUND AND AIMS:Troglitazone is a newly developed antidiabetic drug and is indicated to be useful for the treatment of patients with type II diabetes mellitus. Recently, however, it became clear that troglitazone could cause liver dysfunction in some patients. In addition, a relationship between the activation of t...

journal_title：Journal of gastroenterology and hepatology

authors： Jia DM,Tabaru A,Akiyama T,Abe S,Otsuki M

更新日期：2000-10-01 00:00:00

abstract：BACKGROUND AND AIM:Controversy continues as to whether nutcracker esophagus (NE) is a 'real' manometric disease due to its poor correlation with clinical symptoms such as chest pain or dysphagia. While new NE criteria were proposed in a recent study, that study included NE patients both with and without gastroesophagea...

journal_title：Journal of gastroenterology and hepatology

authors： Jung KW,Jung HY,Yoon IJ,Kim DH,Chung JW,Oh HC,Choi KS,Choi KD,Song HJ,Lee GH,Kim JH

更新日期：2010-07-01 00:00:00

abstract：BACKGROUND AND AIM:The attenuated antisecretory activity observed during continuous administration of ranitidine has been described as tolerance. However, it remains unclear whether a similar phenomenon occurs with other histamine H2 receptor antagonists (H2RA). We investigated whether tolerance to famotidine, a strong...

journal_title：Journal of gastroenterology and hepatology

authors： Komazawa Y,Adachi K,Mihara T,Ono M,Kawamura A,Fujishiro H,Kinoshita Y

更新日期：2003-06-01 00:00:00