Magnetic resonance spectroscopic changes in Alzheimer's disease.

abstract：:N-type calcium channels both generate the initial calcium signal to trigger neurotransmitter release and also interact with synaptic release proteins at many mammalian central nervous system synapses. Two isoforms of the alpha 1B N-type channel from rat brain (alpha 1B-I and alpha 1B-II) were found to differ in four r...

journal_title：Annals of the New York Academy of Sciences

authors： Stea A,Dubel SJ,Snutch TP

更新日期：1999-04-30 00:00:00

abstract：:The LGR7/RXFP1 and LGR8/RXFP2 receptors are unique receptors among the G-protein-coupled receptors (GPCRs) in having a low-density lipoprotein class A (LDL-A) module. Their complex gene organization, among the intron-richest of the GPCRs, suggests that alternative splicing is a common occurrence. We have therefore inv...

journal_title：Annals of the New York Academy of Sciences

authors： Kern A,Bryant-Greenwood GD

更新日期：2009-04-01 00:00:00

abstract：:Photochemical smog is caused by a free-radical chain mechanism which converts NO to NO2. The NO2 further reacts to produce ozone, nitric acid, and peracylnitrates. This chain mechanism can be inhibited by suitable free-radical scavengers. The chemistry and toxicology of one such free-radical scavenger, diethylhydroxyl...

journal_title：Annals of the New York Academy of Sciences

authors： Heicklen J

更新日期：1987-01-01 00:00:00

abstract：:Gonadal hormones, particularly androgens, direct certain aspects of brain development and exert permanent influences on sex-typical behavior in nonhuman mammals. Androgens also influence human behavioral development, with the most convincing evidence coming from studies of sex-typical play. Girls exposed to unusually ...

journal_title：Annals of the New York Academy of Sciences

authors： Hines M

更新日期：2003-12-01 00:00:00

abstract：:The large-scale differential gene expression in lymphomononuclear cells of six patients with recently diagnosed type), and six normal individuals matched to patients for sex and age were studied. Glass slides containing 4608 cDNAs from the IMAGE library were spotted using robotic technology. Statistical analysis was c...

journal_title：Annals of the New York Academy of Sciences

authors： Rassi DM,Junta CM,Fachin AL,Sandrin-Garcia P,Mello S,Marques MM,Fernandes AP,Foss-Freitas MC,Foss MC,Sakamoto-Hojo ET,Passos GA,Donadi EA

更新日期：2006-10-01 00:00:00

abstract：:Aging is the outcome of the contest between chemistry and biology in living systems. Chronic, cumulative chemical modifications compromise the structure and function of biomolecules throughout the body. Proteins with long life spans serve as cumulators of exposure to chemical damage, which is detectable in the form of...

journal_title：Annals of the New York Academy of Sciences

authors： Baynes JW

更新日期：2002-04-01 00:00:00

abstract：:Continuous dopamine (DA) stimulation is a therapeutic approach that applies to the treatment of motor fluctuations due to pulsatile DA stimulation in Parkinson's disease (PD), to cure the abuse of drugs, such as cocaine or amphetamine (which produce short-lasting peaks of extracellular DA), and as a safe therapeutic a...

journal_title：Annals of the New York Academy of Sciences

authors： Biagioni F,Busceti CL,Molinaro G,Battaglia G,Giorgi FS,Ruggieri S,Fornai F

更新日期：2006-08-01 00:00:00

abstract：:Shigella, a Gram-negative bacterial species of the family Enterobacteriaceae, causes bacillary dysentery in humans, an acute rectocolitis that reflects the capacity of the microorganism to disrupt, invade, and cause the inflammatory destruction of the intestinal epithelium. Here, the pathogenesis of Shigella infection...

journal_title：Annals of the New York Academy of Sciences

authors： Sansonetti PJ

更新日期：2006-08-01 00:00:00

abstract：:The present study investigates the impact of emotional deficits on implicit and explicit memory for musical stimuli in patients with Alzheimer's disease and elderly depressed patients. Results showed that unlike Alzheimer's patients, depressed patients were unable to develop a positive affective bias of judgment for p...

journal_title：Annals of the New York Academy of Sciences

authors： Quoniam N,Ergis AM,Fossati P,Peretz I,Samson S,Sarazin M,Allilaire JF

更新日期：2003-11-01 00:00:00

abstract：:Masting, the highly variable and synchronous production of seeds across a population of perennial plants, is an ecologically important, but still poorly understood, phenomenon. While much is known about the fitness benefits of masting and its effects on seed consumers and trophic interactions, less is understood about...

journal_title：Annals of the New York Academy of Sciences

authors： Crone EE,Rapp JM

更新日期：2014-08-01 00:00:00

abstract：:A diagnostic test is particularly beneficial if it reveals the level of susceptibility prior to onset of a disease process. In the case of childhood caries, such a diagnostic test affords the opportunity for preventive measures to be implemented before caries begins. Salivary glycoproteins contain a wealth of individu...

journal_title：Annals of the New York Academy of Sciences

authors： Denny PC,Denny PA,Takashima J,Galligan J,Navazesh M

更新日期：2007-03-01 00:00:00

abstract：:We have previously shown that bone marrow will seed and proliferate in normal recipients. Transfusion of 50 million cells on each of 4 or 5 consecutive days, a total of 200-250 million cells, resulted in the recipient's marrow being 20-40% of donor origin. The present paper reported on the marked enhancement of prolif...

journal_title：Annals of the New York Academy of Sciences

authors： Brecher G,Mulcahy K,Tjio JH,Raveché E

更新日期：1985-01-01 00:00:00

abstract：:This paper reviews a series of my heat transfer studies of on the so-called "self-rewetting" fluids, in which the Marangoni effect due to concentration gradient and the thermocapillary flow cooperatively result in a strong liquid inflow at the nucleation sites in the course of boiling. First of all, the background of ...

journal_title：Annals of the New York Academy of Sciences

authors： Abe Y

更新日期：2006-09-01 00:00:00

abstract：:Ascorbic acid has been found to interact with several elements in such a manner as to render them less available for animals. This property of the vitamin has a negative effect on the animals fed a copper-deficient diet, but a positive effect on those fed toxic levels of copper, selenium, vanadium, and cobalt. The eff...

journal_title：Annals of the New York Academy of Sciences

authors： Hill CH

更新日期：1980-01-01 00:00:00

abstract：:The concepts of the ventral striatopallidal system and extended amygdala have significantly improved our understanding of basal forebrain organization. As a result of these and other advances during the last twenty years, many of the most prominent basal forebrain structures, including the nucleus accumbens, olfactory...

journal_title：Annals of the New York Academy of Sciences

authors： de Olmos JS,Heimer L

更新日期：1999-06-29 00:00:00

abstract：:The discovery of mtDNA types common to Asians and Amerinds (types A, B, C, and D) forced investigators to search for those nations of Asia which, though not considered the ancestors of the Amerinds, have retained a close genetic resemblance with them. We collected samples and studied the gene pools of the Turkic-speak...

journal_title：Annals of the New York Academy of Sciences

authors： Zakharov IA,Derenko MV,Maliarchuk BA,Dambueva IK,Dorzhu CM,Rychkov SY

更新日期：2004-04-01 00:00:00

abstract：:This paper will review our recent data relevant to the antioxidant effects of N-acetylserotonin (NAS), the immediate precursor of melatonin, the pineal gland indole. Mechanisms of the antioxidant effects of NAS might involve interaction with melatonin type 3 receptors and nonreceptor mechanisms such as stimulation of ...

journal_title：Annals of the New York Academy of Sciences

authors： Oxenkrug G

更新日期：2005-08-01 00:00:00

abstract：:Glucose conversion by brain synaptosomes can be regarded as a special case of intrinsic kinetic properties of the enzyme substrate system. Temperature modulation of apparent K(m) for this process can be described with our kinetic model. Using experimental data and the kinetic model, the minimal K(m) value for glucose ...

journal_title：Annals of the New York Academy of Sciences

authors： Marjanović M,Zivadinović D,Dzakula Z,Andjus RK

更新日期：2005-06-01 00:00:00

abstract：:Language and music are human universals involving perceptually discrete elements organized in hierarchically structured sequences. The set of principles governing the combination of these structural elements into sequences is known as syntax. A violation of expectancies concerning syntactic regularities may be reflect...

journal_title：Annals of the New York Academy of Sciences

authors： Jentschke S,Koelsch S,Friederici AD

更新日期：2005-12-01 00:00:00

abstract：:Efficient conservation management is particularly important because current spending is estimated to be insufficient to conserve the world's biodiversity. However, efficient management is confounded by uncertainty that pervades conservation management decisions. Uncertainties exist in objectives, dynamics of systems, ...

journal_title：Annals of the New York Academy of Sciences

authors： McCarthy MA

更新日期：2014-08-01 00:00:00

abstract：:The alteration of oligosaccharide structures through genetic manipulation of glycosyltransferase activities is now a reality. It is apparent that this technique has greater consequences on oligosaccharide structure when an exogenous enzyme is introduced into cells, and in particular when this enzyme is responsible for...

journal_title：Annals of the New York Academy of Sciences

authors： Youakim A,Shur BD

更新日期：1994-11-30 00:00:00

abstract：:Expression analysis and epidemiologic studies have provided indirect evidence that proteinases and growth factors play a role in the development of atherosclerosis and complications such as aneurysm formation and plaque rupture. Studies using genetically altered mice have proven to be an elegant tool to study the caus...

journal_title：Annals of the New York Academy of Sciences

authors： Luttun A,Carmeliet P

更新日期：2001-12-01 00:00:00

abstract：:Social motor coordination (SMC) pertains to the timing of contingent movements during social interactions and is of high relevance for successful social and musical interactions. Semi-automated, objective methods are increasingly being used to analyze SMC, though it is unclear if these methods are feasible in naturali...

journal_title：Annals of the New York Academy of Sciences

authors： Pfeiffer R,Wallace M,Lense M

更新日期：2018-05-04 00:00:00

abstract：:Hyperactivity of the hypothalamo-pituitary-adrenal (HPA) axis is often observed in association with and even prior to the onset of major depression. It is presently unclear (1) which molecular and cellular processes contribute to hyperactivity of parvocellular hypothalamic neurons (key regulators of the HPA system) an...

journal_title：Annals of the New York Academy of Sciences

authors： Joëls M,Verkuyl JM,Van Riel E

更新日期：2003-12-01 00:00:00

abstract：:Whole body exposure of rabbits to microwave radiation causes a decrease in ascorbic acid in the lens. In our study, rabbit lenses maintained in culture medium (37 degrees C) were exposed to either pulsed or continuous wave S-band radiation for 10-15 min at power densities between 0 and 200 mW/cm-2. Total ascorbic acid...

journal_title：Annals of the New York Academy of Sciences

authors： Weiter JJ,Finch ED,Schulz W,Frattali V

更新日期：1975-02-28 00:00:00

abstract：:Human germ-cell tumors (GCTs) are a heterogeneous group of neoplasms. Based on epidemiology, anatomical site of presentation, histology, chromosomal constitution, and pattern of genomic imprinting, GCTs are classified into five entities. Within the testis, three types of GCTs can be diagnosed: type I (teratomas and yo...

journal_title：Annals of the New York Academy of Sciences

authors： Looijenga LH,Gillis AJ,Stoop HJ,Hersmus R,Oosterhuis JW

更新日期：2007-12-01 00:00:00

abstract：:The neurotransmitter serotonin (5-HT) has been implicated in the modulation of aggression in animals and humans. A longstanding dogma that aggression and serotonergic activity are inversely related has to be abandoned in light of many new findings. Trait and state aggression are differentially regulated by the 5-HT sy...

journal_title：Annals of the New York Academy of Sciences

authors： Olivier B

更新日期：2004-12-01 00:00:00

abstract：:The present experiments were conducted to determine the effects of neurotensin on secretion of a variety of anterior pituitary hormones. Conscious rats with indwelling cannulae in the third ventricle and external jugular vein were used and the effects on plasma hormone levels measured by radioimmunoassay. Neurotensin ...

journal_title：Annals of the New York Academy of Sciences

authors： McCann SM,Vijayan E,Koenig J,Krulich L

更新日期：1982-01-01 00:00:00

abstract：:Low- and high-frequency cortical oscillations play an important role in speech processing. Low-frequency neural oscillations in the delta (<4 Hz) and theta (4-8 Hz) bands entrain to the prosodic and syllabic rates of speech, respectively. Theta band neural oscillations modulate high-frequency neural oscillations in th...

journal_title：Annals of the New York Academy of Sciences

authors： Lizarazu M,Lallier M,Molinaro N

更新日期：2019-10-01 00:00:00

abstract：:The purpose of this study was to determine whether the previously reported differences in adenylate cyclase activity between the sarcolemma of normal and dystrophic chick muscles are also found in the SR, to search for a possible relationship between the adenylate cyclase changes and the pathophysiology of dystrophy, ...

journal_title：Annals of the New York Academy of Sciences

authors： Rodan GA,Rodan SB,Raible DG,Cutler LS,Wacholtz M,Sha'afi RI

更新日期：1979-01-01 00:00:00