Leptin levels and body fatness in children: effects of gender, ethnicity, and sexual development.

abstract：INTRODUCTION:Very early preterm infants (VPIs) are exposed to unpredictable noise in neonatal intensive care units. Their ability to perceive moderate acoustic environmental changes has not been fully investigated. RESULTS:Physiological values of the 598 isolated sound peaks (SPs) that were 5-10 and 10-15 dB slow-resp...

journal_title：Pediatric research

authors： Kuhn P,Zores C,Pebayle T,Hoeft A,Langlet C,Escande B,Astruc D,Dufour A

更新日期：2012-04-01 00:00:00

abstract：:The purpose of this study was to investigate the effect of constant light in a neonatal care unit on the development of the sleep-and-wakefulness rhythm in preterm infants. Two groups of infants (57 preterm infants without other complications and 58 healthy term infants) were prospectively studied over infancy by a da...

journal_title：Pediatric research

authors： Shimada M,Segawa M,Higurashi M,Akamatsu H

更新日期：1993-02-01 00:00:00

abstract：:The treatment of multiple acyl-CoA-dehydrogenase deficiency (MADD) includes a low-fat, low-protein, high-carbohydrate diet, avoiding long fasting periods. However, there is no useful biochemical marker to determine the response to different diets or fasting periods. The aims of this study are to report a patient with ...

journal_title：Pediatric research

authors： Abdenur JE,Chamoles NA,Schenone AB,Jorge L,Guinle A,Bernard C,Levandovskiy V,Fusta M,Lavorgna S

更新日期：2001-07-01 00:00:00

abstract：:In the small bowel of patients with cystic fibrosis, primary defects involving both chloride transport and mucus secretion have been demonstrated, but there is no general consensus about the morphologic counterpart of functional and biochemical abnormalities. We have studied the intestinal mucosa in a group of patient...

journal_title：Pediatric research

authors： Sbarbati A,Bertini M,Catassi C,Gagliardini R,Osculati F

更新日期：1998-02-01 00:00:00

abstract：:Aspiration is a major cause of lung disease in infants and young children. As the symptoms and signs of aspiration are not specific, the diagnosis is delayed due to a low index of suspicion and low sensitivity and specificity of the available diagnostic tests. In the present study, we evaluated the utility of microsph...

journal_title：Pediatric research

authors： Springer C,Benita S,Sherman Y,Gursoy N,Gilhar D,Avital A

更新日期：2005-09-01 00:00:00

abstract：:Despite the availability of successful prevention strategies to prevent excessive hyperbilirubinemia, the neurological sequelae of bilirubin neurotoxicity (BNTx) still occur throughout the world. Kernicterus, encephalopathy due to BNTx, is now understood to be a spectrum of severity and phenotypes known as kernicterus...

journal_title：Pediatric research

authors： Riordan SM,Shapiro SM

更新日期：2020-01-01 00:00:00

abstract：:This report describes a third mucopolysaccharidosis in animals: canine mucopolysaccharidosis VII. The affected dog was the offspring of a father-daughter mating. Weakness in the rear legs was evident at 8 weeks of age and became progressively worse. He had a large head, a shortened maxilla, and corneal granularities. ...

journal_title：Pediatric research

authors： Haskins ME,Desnick RJ,DiFerrante N,Jezyk PF,Patterson DF

更新日期：1984-10-01 00:00:00

abstract：:This patient presented on the first day of life with pronounced lactic acidosis with an elevated lactate/pyruvate ratio. Urine organic acids showed Krebs cycle metabolites and mildly elevated methylmalonate and methylcitrate. The acylcarnitine profile showed elevated propionylcarnitine and succinylcarnitine. Amino aci...

journal_title：Pediatric research

authors： Van Hove JL,Saenz MS,Thomas JA,Gallagher RC,Lovell MA,Fenton LZ,Shanske S,Myers SM,Wanders RJ,Ruiter J,Turkenburg M,Waterham HR

更新日期：2010-08-01 00:00:00

abstract：BACKGROUND:Current tools to predict the severity of respiratory syncytial virus (RSV) infection might be improved by including immunological parameters. We hypothesized that a combination of inflammatory markers would differentiate between severe and mild disease in RSV-infected children. METHODS:Blood and nasopharyng...

journal_title：Pediatric research

authors： Brand HK,Ferwerda G,Preijers F,de Groot R,Neeleman C,Staal FJ,Warris A,Hermans PW

更新日期：2013-02-01 00:00:00

abstract：:A 10-year longitudinal study was conducted on 16 prepubescent youngsters who had undergone successful weight reduction. Their ages ranged from 2 to 10 years when the study began. In all subjects, weight reduction proceeded only by a decrease in adipose cell size (from 0.62 +/- 0.02 to 0.46 +/- 0.02 micrograms lipid pe...

journal_title：Pediatric research

authors： Ginsberg-Fellner F,Knittle JL

更新日期：1981-10-01 00:00:00

abstract：:To determine the pathophysiologic significance of pertussis toxin (PT) on the human beta-adrenergic system, beta-adrenoceptor (beta-R)-density and cyclic AMP response of peripheral mononuclear blood cells (MN leukocytes) were studied in children during the paroxysmal stage of natural pertussis infection, after vaccina...

journal_title：Pediatric research

authors： Griese M,Sideropoulou O,Reinhardt D

更新日期：1989-02-01 00:00:00

abstract：BACKGROUND:Adolescents born preterm have altered hypothalamic-pituitary-adrenal axis function with a blunted cortisol stress response, however, the influences of intrauterine growth restriction and race are unclear. METHODS:We measured salivary cortisol before and 20 min after a maximal-exercise stress test and calcul...

journal_title：Pediatric research

authors： Brown CL,Myers K,South AM,Shaltout HA,Jensen ET,Nixon PA,Washburn LK

更新日期：2020-05-01 00:00:00

abstract：:Monocyte chemoattractant protein-1 (MCP-1), acting through its C-C chemokine receptor 2 (CCR-2), has important roles in inflammation, angiogenesis, and wound repair. The individual and combined effects of inhaled nitric oxide (NO) and hyperoxia on lung MCP-1 and CCR-2 in relation to lung leukocyte dynamics are unknown...

journal_title：Pediatric research

authors： Ekekezie II,Thibeault DW,Garola RE,Truog WE

更新日期：2001-11-01 00:00:00

abstract：:Bacillus Calmette-Guerin (BCG) vaccination can protect animals from asthma, but the effect of BCG on childhood asthma prevention is controversial in humans. To verify the hypothesis that the BCG anti-asthma effect in childhood might be reversed by a respiratory virus infection, newborn BALB/c mice were divided into fi...

journal_title：Pediatric research

authors： Li R,Yang X,Wang L,Liu E

更新日期：2006-02-01 00:00:00

abstract：BACKGROUND:Appearance of sleep cycling has been associated with good outcome in term and preterm infants, but the normal time of its appearance has not been determined. The objectives of this study were, to correlate the time of sleep cycling appearance and the length of quiet sleep in neonates with different degrees o...

journal_title：Pediatric research

authors： Abramsky R,Stavsky M,Novack V,Shany E

更新日期：2020-03-01 00:00:00

abstract：:Neurogenesis persists throughout life in the rodent subventricular zone (SVZ) and increases in the adult after brain injury. In this study, postnatal day 7 (P7) rats underwent right carotid artery ligation followed by 8% O2 exposure for 90 min, a lesioning protocol that resulted in ipsilateral forebrain hypoxic-ischem...

journal_title：Pediatric research

authors： Ong J,Plane JM,Parent JM,Silverstein FS

更新日期：2005-09-01 00:00:00

abstract：:We studied the effects of a diet that was low in fat, high in carbohydrate (CHO) on milk lipid composition and de novo endogenous fatty acid synthesis by the mammary gland in five lactating women. The women consumed either a low fat (LF) (5% fat, 80% CHO) diet or a high fat (HF) (40% fat, 45% CHO) diet. Fat synthesis ...

journal_title：Pediatric research

authors： Hachey DL,Silber GH,Wong WW,Garza C

更新日期：1989-01-01 00:00:00

abstract：:Young adult macrosomic offspring of streptozotocin-induced mildly hyperglycemic rats exhibit accelerated growth through the first 10 wk of age. At 10 wk, oral glucose loading resulted in elevated plasma insulin and glucose concentrations compared to controls. To assess the mechanism of the abnormal glucose tolerance i...

journal_title：Pediatric research

authors： Gelardi NL,Cha CJ,Oh W

更新日期：1991-07-01 00:00:00

abstract：:A series of in vivo experiments is described in which [1-13C]phytanic acid was given as an oral substrate to a healthy subject and two patients showing an impairment in phytanic acid degradation, one with Refsum's disease and one with chondrodysplasia punctata. After intake of the substrate by the control in a dose of...

journal_title：Pediatric research

authors： ten Brink HJ,Schor DS,Kok RM,Stellaard F,Kneer J,Poll-The BT,Saudubray JM,Jakobs C

更新日期：1992-11-01 00:00:00

abstract：:The mitochondria play a major role in the regulation of intracellular calcium. Despite the fact that the enterocytes receive the majority of absorbed calcium, the role of the intestinal mitochondria in calcium transport during maturation is not known. Therefore, the current studies were designed to characterize calciu...

journal_title：Pediatric research

authors： Kikuchi T,Kikuchi K,Arab N,Ghishan FK

更新日期：1989-01-01 00:00:00

abstract：:Milk gangliosides inhibit Vibrio cholerae enterotoxin and Escherichia coli heat-labile enterotoxin. Human milk gangliosides showed considerably higher enterotoxin-inhibitory activity compared to bovine and formula milk gangliosides as measured in vitro by enzyme-linked immunosorbent assay and in vivo in rabbit small b...

journal_title：Pediatric research

authors： Laegreid A,Otnaess AB,Fuglesang J

更新日期：1986-05-01 00:00:00

abstract：:Galactose metabolism was studied in human ovarian tissue obtained from 14 women controls between 21 and 72 y of age, and one 21-y-old galactosemic patient with hypergonadotrophic hypogonadism. Tissue slices were incubated with 1-14C-galactose, and labeled intermediates were analyzed by anion-exchange column chromatogr...

journal_title：Pediatric research

authors： Xu YK,Ng WG,Kaufman FR,Lobo RA,Donnell GN

更新日期：1989-02-01 00:00:00

abstract：:The fetal inflammatory response has been suggested as causal in neonatal morbidity. Serial levels of circulating cytokines were evaluated in 74 infants with a mean gestational age (GA) of 27.1 wk. Pro-inflammatory [tumor necrosis factor-alpha (TNF-alpha), interferon-gamma (IFN-gamma), IL-1 beta, IL-2, IL-6, IL-8, IL-1...

journal_title：Pediatric research

authors： Hansen-Pupp I,Harling S,Berg AC,Cilio C,Hellström-Westas L,Ley D

更新日期：2005-11-01 00:00:00

abstract：:Despite effective antibiotic treatment, neuronal injury is frequent among children and adults with bacterial meningitis resulting in a high rate of death and neurologic sequelae. The hematopoietic cytokine erythropoietin (EPO) provides neuroprotection in models of acute and chronic neurologic diseases. We studied whet...

journal_title：Pediatric research

authors： Spreer A,Gerber J,Hanssen M,Nau R

更新日期：2007-12-01 00:00:00

abstract：:Spring steel coils have been used to occlude abnormal vessels in patients with a congenital heart malformation. However, long-term adverse effects of steel spring coils remain uncertain, although some long-term results appear to be good. The purpose of this study was to evaluate the angiographic and histologic results...

journal_title：Pediatric research

authors： Ino T,Kishiro M,Yamashiro Y,Tanaka A,Ito H

更新日期：1998-04-01 00:00:00

abstract：:The mitochondrial trifunctional protein (TFP) is a multienzyme complex of the beta-oxidation cycle. Human TFP is an octamer composed of four alpha-subunits harboring long-chain enoyl-CoA hydratase and long-chain L-3-hydroxyacyl-CoA dehydrogenase and four beta-subunits encoding long-chain 3-ketoacyl-CoA thiolase. Mutat...

journal_title：Pediatric research

authors： Spiekerkoetter U,Khuchua Z,Yue Z,Bennett MJ,Strauss AW

更新日期：2004-02-01 00:00:00

abstract：:The isobutyryl-CoA dehydrogenase (IBD) enzyme is involved in the degradation of valine. IBD deficiency was first reported in 1998 and subsequent genetic investigations identified acyl-CoA dehydrogenase (ACAD) 8, now IBD, as the gene responsible for IBD deficiency. Only three individuals homozygous or compound heterozy...

journal_title：Pediatric research

authors： Pedersen CB,Bischoff C,Christensen E,Simonsen H,Lund AM,Young SP,Koeberl DD,Millington DS,Roe CR,Roe DS,Wanders RJ,Ruiter JP,Keppen LD,Stein Q,Knudsen I,Gregersen N,Andresen BS

更新日期：2006-09-01 00:00:00

abstract：BACKGROUND:We examined whether increased dairy intake was associated with changes in the levels of bone-related biochemical markers in overweight/obese adolescent girls undergoing a 12-week diet and exercise intervention. METHODS:Thirty-five girls were assigned to a low dairy group (LDa; 0-2 servings/day; n = 16) or a...

journal_title：Pediatric research

authors： Josse AR,Ludwa IA,Kouvelioti R,Calleja M,Falk B,Ward WE,Klentrou P

更新日期：2020-12-01 00:00:00

abstract：:Prenatal maternal stress has been shown to impair functioning in nonhuman primate offspring. Little is known about the effects of prenatal stress on intellectual and language development in humans because it is difficult to identify sufficiently large samples of pregnant women who have been exposed to an independent s...

journal_title：Pediatric research

authors： Laplante DP,Barr RG,Brunet A,Galbaud du Fort G,Meaney ML,Saucier JF,Zelazo PR,King S

更新日期：2004-09-01 00:00:00

abstract：INTRODUCTION:In preterm neonates, peroxides contaminating total parenteral nutrition (TPN) contribute to oxidative stress, which is suspected to be a strong inducer of hepatic complications related to prematurity. Recently, others reported that hexapeptides derived from human milk (HM) exerted free radical-scavenging a...

journal_title：Pediatric research

authors： Miloudi K,Tsopmo A,Friel JK,Rouleau T,Comte B,Lavoie JC

更新日期：2012-06-01 00:00:00