Abstract：
:Endothelial dysfunction, a marker for atherosclerosis and hence arterial disease, has recently been proffered as the main offender within the vascular system to predict not only the future onset of erectile dysfunction (ED) but also as the main cause of the ED. To glean more insight into whether arterial disease is indeed operative during the early onset of ED, we reviewed the duplex ultrasound scans of 23 men with ED who were younger than 50 years of age. Depending on the criteria used for abnormal arterial responses, it was determined in this cohort of young men that there was only a 4-13% incidence of abnormal arterial responses. These observations suggest that the penile arterial system does not appear to be primarily involved in the etiology of the majority cases of ED that occur in young men.
journal_name
Int J Impot Resjournal_title
International journal of impotence researchauthors
Rajfer J,Valeriano J,Sinow Rdoi
10.1038/ijir.2013.17subject
Has Abstractpub_date
2013-11-01 00:00:00pages
217-20issue
6eissn
0955-9930issn
1476-5489pii
ijir201317journal_volume
25pub_type
杂志文章abstract：:Hard flaccid (HF) is a group of symptoms that significantly affects a man's sexual and social life. As this syndrome has only been reported in several patient forums, exact prevalence of this rare condition is unknown. Currently, no scientific literature exists of the syndrome. We, hereby, aimed to present four cases ...
journal_title：International journal of impotence research
pub_type： 杂志文章
doi：10.1038/s41443-019-0133-z
更新日期：2020-03-01 00:00:00
abstract：:Erectile dysfunction (ED) is linked to various cardiovascular risk factors and may therefore serve as a predictor of cardiovascular events. To gain further insight into this relationship, we reviewed all data regarding hospital admission for cardial or cerebral vascular disease that occurred until 2008 in a cohort of ...
journal_title：International journal of impotence research
pub_type： 杂志文章,随机对照试验
doi：10.1038/ijir.2009.40
更新日期：2010-01-01 00:00:00
abstract：:During penile pharmacotesting, anxiety may overcome complete smooth muscle relaxation and lead to false positive diagnosis of organic male erectile dysfunction (ED). We tested the efficacy and safety of re-dosing of PGE1 alone versus combination of PGE, and the alpha1,2-blocker phentolamine (PHE) to improve an incompl...
journal_title：International journal of impotence research
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1038/sj.ijir.3900477
更新日期：2000-02-01 00:00:00
abstract：:A concise, reliable means of assessing erectile dysfunction (ED) in large, multidisciplinary population-based studies is needed. A single, direct question for self-assessed ED was assessed in the population-based sample of the Massachusetts Male Aging Study (MMAS). Of the 1156 respondents to the 1995-97 MMAS follow-up...
journal_title：International journal of impotence research
pub_type： 杂志文章
doi：10.1038/sj.ijir.3900542
更新日期：2000-08-01 00:00:00
abstract：:The aim of this study is to review the current literature that reports outcomes of Peyronie's disease (PD) grafting surgery, with a special focus on novel approaches and grafting materials. For this purpose, a literature review was performed through PubMed between 2014 and 2019 regarding grafting techniques in PD reco...
journal_title：International journal of impotence research
pub_type： 杂志文章,评审
doi：10.1038/s41443-019-0179-y
更新日期：2020-01-01 00:00:00
abstract：:The frequency of sexual dysfunction (SD) is not very well known in patients with chronic hepatitis C. In this study, the prevalence of SD and its correlations with psychological and biological variables was assessed in 46 HCV positive patients. The mean age of patients was 46.4+/-9.4 y; the mean duration of HCV infect...
journal_title：International journal of impotence research
pub_type： 杂志文章
doi：10.1038/sj.ijir.3901267
更新日期：2005-03-01 00:00:00
abstract：:We estimated the incidence of erectile dysfunction (ED) in a population-based sample during 5-y follow-up and determined how the rate was affected by sociodemographic and life-style factors. The target population comprised all men aged 50, 60 or 70 y residing in the city of Tampere or 11 surrounding municipalities in ...
journal_title：International journal of impotence research
pub_type： 杂志文章
doi：10.1038/sj.ijir.3901196
更新日期：2004-10-01 00:00:00
abstract：:Despite extensive research into the toxicity of bisphenol A (BPA), no report of its effect on erectile function exists. We performed this study to investigate the effect of BPA on erectile function. New Zealand white rabbits were treated intraperitoneally with 150 mg/kg of BPA every other day for 12 days (cumulative d...
journal_title：International journal of impotence research
pub_type： 杂志文章
doi：10.1038/sj.ijir.3900734
更新日期：2001-10-01 00:00:00
abstract：:A lack of uniformity exists for insurance payer coverage for all categories of penile prostheses (PP). We sought to determine common insurance coverage criteria and barriers to implantation across common insurance plans from healthcare referral regions (HRR) nationwide. Coverage criteria and stipulations were reviewed...
journal_title：International journal of impotence research
pub_type： 杂志文章
doi：10.1038/s41443-019-0226-8
更新日期：2021-01-01 00:00:00
abstract：PURPOSE:Aim of this systematic review is to evaluate functional outcomes (Qmax, QoL, IPSS, PVR), sexual outcome (erectile dysfunction and anejaculation rate), and adverse events evaluated according to the Clavien-Dindo classification. METHODS:The bibliographic search with the included terms (prostate, benign prostatic...
journal_title：International journal of impotence research
pub_type： 杂志文章
doi：10.1038/s41443-019-0158-3
更新日期：2019-11-01 00:00:00
abstract：BACKGROUND:The objective was to collect characteristics of patients with male erectile disorder (MED) attending a male sexual dysfunction clinic and determine the level of psychological morbidity whilst recruiting subjects into a psychotherapy study. METHODS:This was a study of data of 132 patients diagnosed as having...
journal_title：International journal of impotence research
pub_type： 杂志文章
doi：10.1038/sj.ijir.3900295
更新日期：1997-12-01 00:00:00
abstract：:The objective was to investigate the cellular effect and action mechanism of Artemisia capillaris extract (ACE) and its component, scopoletin, on penile corpus cavernosum smooth muscle (PCCSM). In vitro study with PCCSM, the precontracted PCCSM with phenylephrine was treated with ACE or scopoletin. Cyclic nucleotides ...
journal_title：International journal of impotence research
pub_type： 杂志文章
doi：10.1038/ijir.2015.23
更新日期：2015-11-01 00:00:00
abstract：:A consecutive series of 52 men presenting with erectile dysfunction were assessed with (i) standardized sexual history, (ii) nocturnal penile tumescence and rigidity monitoring (NPTR), (iii) Rigiscan assessment of response to intracavernosal papaverine or prostaglandin injection (ICI), and (iv) duplex ultrasonography....
journal_title：International journal of impotence research
pub_type： 杂志文章
doi：
更新日期：1993-09-01 00:00:00
abstract：:Erectile dysfunction (ED) can be an early and first sign of an underlying systemic disease. A screening program is offered by the Israeli Defense Force for career servicemen at the staff periodic examination center (SPEC), the aim of which was early detection of morbidity. We introduced the Sexual Human Inventory for ...
journal_title：International journal of impotence research
pub_type： 杂志文章
doi：10.1038/sj.ijir.3901173
更新日期：2004-08-01 00:00:00
abstract：:The objective of this study was to evaluate the effect on erections of impeding venous blood flow following intracavernosal injections of prostaglandin E1. Dispersion of injected X-ray contrast medium indicated that application of the RMRI penile clamp to the base of the penis retarded venous outflow. The clamp was th...
journal_title：International journal of impotence research
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1995-03-01 00:00:00
abstract：:Modulation of the adrenergic activity and interfering with channels such as potassium channels may affect relaxation and contraction of the corpus cavernosum. Sildenafil is a selective phosphodiesterase-5 inhibitor, proven effective in treating erectile dysfunction. In this study, the effect of sildenafil citrate on a...
journal_title：International journal of impotence research
pub_type： 杂志文章
doi：10.1038/sj.ijir.3901590
更新日期：2007-11-01 00:00:00
abstract：:Fifty partial and non-responders (Clinical Global Impression-Sexual Function (CGI-SF) score>2), out of 76 men who completed a 6-week, double-blind, placebo-controlled trial of sildenafil treatment for serotonergic antidepressant-associated sexual dysfunction, were eligible for an additional 6-week trial of open-label ...
journal_title：International journal of impotence research
pub_type： 杂志文章,随机对照试验
doi：10.1038/sj.ijir.3901502
更新日期：2007-03-01 00:00:00
abstract：:We investigated whether coronary flow reserve (CFR) can be modified by tadalafil, a long-acting phosphodiesterase 5 (PDE5) inhibitor, in patients with documented coronary artery disease (CAD). CFR was non-invasively evaluated in 12 men with a positive history for erectile dysfunction (ED) and angiographically document...
journal_title：International journal of impotence research
pub_type： 临床试验,杂志文章
doi：10.1038/sj.ijir.3901592
更新日期：2008-03-01 00:00:00
abstract：:The aim of this work is evaluate the efficacy of infection control measures with unicomponent penile implants in two ambulatory surgery units in Cairo and Jeddah. This was a retrospective study of 117 consecutive cases. A patient selection and infection control protocol was followed to implant 12 hydraulic, 53 mechani...
journal_title：International journal of impotence research
pub_type： 杂志文章
doi：10.1038/sj.ijir.3900374
更新日期：1999-02-01 00:00:00
abstract：:In order to assess the effectiveness of sildenafil under routine conditions of use in primary care settings and to evaluate its impact on patient's life satisfaction and partner's satisfaction with treatment for erectile dysfunction (ED), an open, multicentre, observational, prospective study was designed in which 281...
journal_title：International journal of impotence research
pub_type： 临床试验,杂志文章,多中心研究
doi：10.1038/sj.ijir.3900782
更新日期：2001-12-01 00:00:00
abstract：:Radical prostatectomy has been shown to have a potential negative impact on penile health. Stretched penile length (SPL), which most closely correlates with erect penile length, was significantly reduced in almost half of men undergoing surgery in several studies. The purpose of this study was to test whether early in...
journal_title：International journal of impotence research
pub_type： 杂志文章
doi：10.1038/sj.ijir.3901561
更新日期：2007-09-01 00:00:00
abstract：:Sildenafil is one of two oral drugs approved for first-line treatment of erectile dysfunction (ED). Anecdotally, some young healthy men who wish to enhance their sexual performance are requesting or abusing sildenafil. In this randomized double-blind, placebo-controlled clinical study, we investigated the effect of si...
journal_title：International journal of impotence research
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1038/sj.ijir.3901005
更新日期：2003-06-01 00:00:00
abstract：:We evaluated spontaneous tumescence after penile prostheses implantation in a retrospective study. A total of 32 patients with three-piece hydraulic implants (17 Mentor Alpha I, 15 AMS Ultrex Plus) were enrolled. Consultation, personal interviews and questionnaires for both the patients and their partners provided the...
journal_title：International journal of impotence research
pub_type： 杂志文章
doi：10.1038/sj.ijir.3900979
更新日期：2003-06-01 00:00:00
abstract：:Penile implant malfunction is usually treated by removal of the original malfunctioning implant followed by replacement with a new device. During replacement, the original implant can be explanted without any difficulty, as it is not adherent to the surrounding tissue. Herein, we describe two cases of tissue ingrowth ...
journal_title：International journal of impotence research
pub_type： 杂志文章
doi：10.1038/sj.ijir.3901217
更新日期：2004-04-01 00:00:00
abstract：:Venous insufficiency of the corpora cavernosa is the second most common cause of erectile dysfunction (ED). A functional insufficiency of the venous system has been hypothesised, but the cause is still unclear. To evaluate a possible endocrine mechanism, we have studied hormone profile in a group of nine patients with...
journal_title：International journal of impotence research
pub_type： 杂志文章
doi：10.1038/sj.ijir.3901287
更新日期：2005-05-01 00:00:00
abstract：:Dissection of the pudendal nerve (PN) and its branches in 71 cadavers revealed anatomic variations not previously described. Knowledge of this variation is necessary to prevent nerve injury resulting in sexual of sensory dysfunction. Because descriptions vary, this study re-evaluated the anatomy of the PN as implicate...
journal_title：International journal of impotence research
pub_type： 杂志文章
doi：10.1038/ijir.2015.10
更新日期：2015-07-01 00:00:00
abstract：:It is well known that the administration of phosphodiesterase type-5 inhibitors (PDE5-Is) may improve erectile function (EF) recovery after bilateral nerve-sparing radical prostatectomy (BNSRP). The aim of our study was to identify predictors of the use of a high number of PDE5-Is (one or more per week) after surgery ...
journal_title：International journal of impotence research
pub_type： 杂志文章
doi：10.1038/ijir.2014.10
更新日期：2014-11-01 00:00:00
abstract：:Number of gender dysphoric people increased over the last few decades with positive social acceptance of transpopulation. Genital gender affirming surgeries are of utmost importance in order to adjust body to the mind of these individuals. Creation of the phallus is usually the last step in transmen transition, which ...
journal_title：International journal of impotence research
pub_type： 杂志文章,评审
doi：10.1038/s41443-020-00346-y
更新日期：2020-08-21 00:00:00
abstract：:Isometric tension measurement using a selective Rho-kinase inhibitor (+)- (R)-trans4-(1-aminoethyl)-N-(4-pyridyl)cyclohexanecarboxamide (Y-27632) and a selective myosin light chain kinase (MLCK) inhibitor 1-(5-iodonaphthalene-1-sulfonyl)-1H-hexahydro-1,4-diazepine hydrochloride (ML7) were used in rabbit clitoral caver...
journal_title：International journal of impotence research
pub_type： 杂志文章
doi：10.1038/sj.ijir.3900911
更新日期：2002-12-01 00:00:00
abstract：:From the files of the outpatient urology department 44 men with ED had undergone both psychophysiological diagnostic screening (PDS, VSS, VSS+VIB, ICI+VSS+VIB) and color Doppler sonography testing (CDS, including VSS). PDS was carried out by one medical physiologist, CDS by one urologist. The diagnoses reached could b...
journal_title：International journal of impotence research
pub_type： 杂志文章
doi：10.1038/sj.ijir.3900838
更新日期：2002-06-01 00:00:00
