Abstract：
:The frequency of sexual dysfunction (SD) is not very well known in patients with chronic hepatitis C. In this study, the prevalence of SD and its correlations with psychological and biological variables was assessed in 46 HCV positive patients. The mean age of patients was 46.4+/-9.4 y; the mean duration of HCV infection was 43.4+/-34.0 months; 52% were male; 89% were living with a spouse. SD was assessed using the Arizona Sexual Experiences Scale (ASEX), the level of anxiety and depression measured with the Hospital Anxiety and Depression Scale (HADS). Biochemical parameters were also assessed. Overall, as indicated by ASEX criteria, SD was observed in 35% of our patients. Of 24 males, 21% described SD; problems with drive (25%), arousal (17%) and erection (17%) were the most frequent complaints. Of 22 female patients, 50% described SD; problems with drive (55%) arousal (50%), and reaching orgasm (59%) were the most frequent complaints. Total ASEX scores were correlated with age (P<0.07, significant at trend level), education (P<0.001), and was higher in female patients (P<0.02). After controlling for the effects of age, sex, education, duration of HCV and marital status, depression levels could still significantly predict the SD (P<0.05). Moreover, even after controlling the effects of all other variables, gamma glutamyl transpeptidase (GGT) levels could predict the SD status of the patients (P<0.05). Our results indicate that the prevalence of SD was 35% in HCV-infected patients and the level of depression and GGT levels were predictive of patients SD status.
journal_name
Int J Impot Resjournal_title
International journal of impotence researchauthors
Soykan A,Boztaş H,Idilman R,Ozel ET,Tüzün AE,Ozden A,Ozden A,Kumbasar Hdoi
10.1038/sj.ijir.3901267subject
Has Abstractpub_date
2005-03-01 00:00:00pages
175-9issue
2eissn
0955-9930issn
1476-5489pii
3901267journal_volume
17pub_type
杂志文章abstract：:The penoscrotal (PS), infrapubic (IP), and subcoronal (SC) incisions are used for inserting an inflatable penile prosthesis (IPP). Each surgical approach has its advantages and disadvantages and experts continue to debate which technique has the best outcomes. We performed a critical review of the published English-la...
journal_title：International journal of impotence research
pub_type： 杂志文章,评审
doi：10.1038/s41443-020-0319-4
更新日期：2020-06-02 00:00:00
abstract：:There is considerable interest in understanding the genetics of erectile dysfunction (ED). Since early twin studies that suggested a genetic component to ED, multiple candidate gene studies have identified genetic variants that may be associated with ED. Genome-wide association studies (GWAS) have overcome some of the...
journal_title：International journal of impotence research
pub_type： 杂志文章,评审
doi：10.1038/s41443-020-00372-w
更新日期：2020-11-10 00:00:00
abstract：:Tamsulosin is the most potent adrenergic alpha-1 antagonist used for the treatment of benign prostatic hyperplasia. Priapism has been reported rarely in patients taking Prazosin, Doxazosin and Terazosin. We describe an otherwise healthy man with recurrent and then persistent unresolved priapism after the use of tamsul...
journal_title：International journal of impotence research
pub_type： 杂志文章
doi：10.1038/sj.ijir.3901281
更新日期：2005-05-01 00:00:00
abstract：:This work aimed to assess the cavernous anti-apoptotic role of using chronic low-dose sildenafil/tadalafil with and without testosterone (T) in aged diabetic rats. In all, 140 Sprague-Dawley aged rats were divided into the following groups: controls; induced diabetic rats; diabetic rats that received intramuscular dep...
journal_title：International journal of impotence research
pub_type： 杂志文章
doi：10.1038/ijir.2010.12
更新日期：2010-07-01 00:00:00
abstract：:Adlay (Coix lachryma-jobi L. var. ma-yuen Stapf.) has long been used as a traditional Chinese medicine for dysfunctions of the endocrine system and inflammation conditions. However, the effect of adlay seed on the endocrine system has not yet been reported. In the present study, the effects and the mechanisms of metha...
journal_title：International journal of impotence research
pub_type： 杂志文章
doi：10.1038/sj.ijir.3901405
更新日期：2006-05-01 00:00:00
abstract：:The aim of the present study was to investigate which PD specific factors (e.g., degree of penile curvature, levels of pain) cause most distress and to further explore whether there are specific subgroups of patients that report particularly high levels of psychological distress. Data were available for N = 119 men wi...
journal_title：International journal of impotence research
pub_type： 杂志文章
doi：10.1038/s41443-018-0029-3
更新日期：2018-08-01 00:00:00
abstract：:This study was aimed to identify characteristics of ED patients who discontinued PDE5i despite successful intercourse. Data were collected using a questionnaire from 34 urologic clinics regardless of the effect (success or failure) of PDE5i treatment by visiting the clinics (717), e-mail (64) or post (101) for 882 ED ...
journal_title：International journal of impotence research
pub_type： 杂志文章
doi：10.1038/ijir.2013.41
更新日期：2014-05-01 00:00:00
abstract：:Premature ejaculation (PE), the most common sexual dysfunctions in men, is characterized by loss or absence of ejaculatory control. PE can be classified as either a lifelong or acquired condition. Although the prevalence of lifelong PE is rather low in the general male population, recent studies demonstrated that the ...
journal_title：International journal of impotence research
pub_type： 杂志文章,评审
doi：10.1038/ijir.2012.12
更新日期：2012-09-01 00:00:00
abstract：:Experimental models to study the effect of agents on penile erection usually include electrical stimulation of peripheral nerves in anesthetized animals combined with systemic or intracavernous injection of drugs. The objective of this study was to demonstrate that conscious rabbits can be used as a simple and quantit...
journal_title：International journal of impotence research
pub_type： 杂志文章
doi：10.1038/sj.ijir.3900703
更新日期：2001-08-01 00:00:00
abstract：:To date, no effective medical approach for the treatment of erectile dysfunction (ED) secondary to ischemic priapism (IP) has been described. The aim of this study was to evaluate the anti-inflammatory, antifibrotic, and antioxidant effects of pirfenidone (PFD) on cavernosal tissue in a rat model of IP. Forty-eight ma...
journal_title：International journal of impotence research
pub_type： 杂志文章
doi：10.1038/s41443-019-0152-9
更新日期：2020-03-01 00:00:00
abstract：:The imbalance between vasoconstrictors and vasodilators may play an important role in the pathogenesis of erectile dysfunction (ED). A total of 36 patients with ED, organogenic [diabetic (n=12) and nondiabetic (n=12)] and psychogenic (n=12) etiology, and 12 healthy adult men as controls were included. The levels of en...
journal_title：International journal of impotence research
pub_type： 杂志文章
doi：10.1038/sj.ijir.3901059
更新日期：2003-12-01 00:00:00
abstract：:Coronavirus disease 2019 (COVID-19) pandemic has been continuing to affect the lives of all people globally. It has been shown that restrictions due to changes in lifestyles lead to mental health problems. This study aims to investigate the effect of COVID-19 pandemic on couples' sexuality. A total of 245 volunteers (...
journal_title：International journal of impotence research
pub_type： 杂志文章
doi：10.1038/s41443-020-00378-4
更新日期：2020-12-16 00:00:00
abstract：:The majority of medical students and medical healthcare providers do not feel comfortable when addressing sexual problems. It was suggested that more courses in sexual health are needed at medical schools to overcome this shortcoming. To assess medical students' interest in and attitude about sexual health education a...
journal_title：International journal of impotence research
pub_type： 杂志文章
doi：10.1038/ijir.2016.25
更新日期：2016-09-01 00:00:00
abstract：:To date, the effects of long-term testosterone (T) administration on the human vagina are not completely understood. Thus, the aim of this study was to investigate the effects of long-term T treatment on vaginal tissue histology, estrogen receptor alpha (ERα) and beta (ERβ) expression and proliferation in female to ma...
journal_title：International journal of impotence research
pub_type： 杂志文章
doi：10.1038/ijir.2013.9
更新日期：2013-09-01 00:00:00
abstract：AIMS OF THIS STUDY:This study evaluated whether human cavernosal myofibroblasts in cell culture is a viable model for the study of the role of oxygen free radicals in the production of collagen types I and III, as observed in Peyronie's disease. METHOD:Human cavernosal cells in primary culture were incubated with 3H-p...
journal_title：International journal of impotence research
pub_type： 杂志文章
doi：10.1038/sj.ijir.3900414
更新日期：1999-08-01 00:00:00
abstract：BACKGROUND:The objective was to collect characteristics of patients with male erectile disorder (MED) attending a male sexual dysfunction clinic and determine the level of psychological morbidity whilst recruiting subjects into a psychotherapy study. METHODS:This was a study of data of 132 patients diagnosed as having...
journal_title：International journal of impotence research
pub_type： 杂志文章
doi：10.1038/sj.ijir.3900295
更新日期：1997-12-01 00:00:00
abstract：:The aim of this work is evaluate the efficacy of infection control measures with unicomponent penile implants in two ambulatory surgery units in Cairo and Jeddah. This was a retrospective study of 117 consecutive cases. A patient selection and infection control protocol was followed to implant 12 hydraulic, 53 mechani...
journal_title：International journal of impotence research
pub_type： 杂志文章
doi：10.1038/sj.ijir.3900374
更新日期：1999-02-01 00:00:00
abstract：:We report a rare complication of a penile prosthesis reservoir removed from the urinary bladder in a patient with a history of radiation therapy and previous abdominal surgery. The reservoir was retrieved by open cystotomy 13 years after original placement. ...
journal_title：International journal of impotence research
pub_type： 杂志文章
doi：10.1038/sj.ijir.3901303
更新日期：2005-05-01 00:00:00
abstract：:The aim of the study was to determine whether any difference would occur in peak systolic velocity (PSV) and end diastolic velocity (EDV) measurements of color Doppler ultrasonography (CDU) between proximal and distal segments of the cavernous arteries obtained at different times. Twenty-six cases have undergone CDU t...
journal_title：International journal of impotence research
pub_type： 杂志文章
doi：10.1038/sj.ijir.3900304
更新日期：1998-03-01 00:00:00
abstract：:Multiple system atrophy (MSA) is a progressive neurodegenerative disease characterized by parkinsonism and cerebellar, autonomic, urinary, and/or pyramidal dysfunction. Urinary and erectile dysfunction (ED) symptoms are prominent early features in men with MSA. Autonomic failure, considered until recently to be the ca...
journal_title：International journal of impotence research
pub_type： 杂志文章
doi：10.1038/sj.ijir.3901014
更新日期：2003-08-01 00:00:00
abstract：:A prospective study was done on 76 patients who underwent surgical correction by corporeal plication of the penile deformity secondary to Peyronie's disease. Nocturnal penile tumescence and rigidity were recorded by RigiScan during three consecutive nights, before and after the operation. A significant number of patie...
journal_title：International journal of impotence research
pub_type： 杂志文章
doi：
更新日期：1995-06-01 00:00:00
abstract：:The activation of cavernous local renin-angiotensin system has an important role in pathogenesis of diabetic erectile dysfunction (ED). In our primary study, we found that angiotensin Type 1 receptor blocker improved the erectile function of diabetic rats. Therefore we explored the losartan in clinical treatment for d...
journal_title：International journal of impotence research
pub_type： 杂志文章,随机对照试验
doi：10.1038/ijir.2012.4
更新日期：2012-11-01 00:00:00
abstract：:Defining the minimal clinically meaningful improvement (MCMI) is crucial to understanding the treatment effects on health-status measures. We estimated the MCMI on the quality of erection questionnaire (QEQ), a validated measure specific to assess erectile quality during sexual intercourse. Data were from two controll...
journal_title：International journal of impotence research
pub_type： 杂志文章,随机对照试验
doi：10.1038/ijir.2009.47
更新日期：2010-01-01 00:00:00
abstract：:Several trials and reviews provide evidence for the efficacy of phosphodiesterase-5 inhibitors in the treatment of erectile dysfunction (ED). However, little is known about the impact of treatment effect modifiers other than concomitant diseases. Our objective was to identify patient and trial characteristics as well ...
journal_title：International journal of impotence research
pub_type： 杂志文章,meta分析
doi：10.1038/sj.ijir.3901479
更新日期：2006-11-01 00:00:00
abstract：:The human T-lymphotropic virus type I (HTLV-I) is a retrovirus associated with a chronic myelopathy known as HTLV-I-Associated Myelopathy or Tropical Spastic Paraparesis (HAM/TSP). The main objective was to assess the frequency of erectile dysfunction (ED) in HTLV-I-infected individuals from Salvador and other cities ...
journal_title：International journal of impotence research
pub_type： 杂志文章
doi：10.1038/sj.ijir.3901335
更新日期：2005-07-01 00:00:00
abstract：:This randomized controlled cross-over study aimed to assess the efficacy and safety of glans penis injection with hyaluronic acid (HA) in treating premature ejaculation (PE). A total of 30 patients with PE were randomly allocated into two groups: group 1 (n = 15) which was subjected to glans penis HA injection and gro...
journal_title：International journal of impotence research
pub_type： 杂志文章,随机对照试验
doi：10.1038/s41443-018-0104-9
更新日期：2019-09-01 00:00:00
abstract：:The first goal of this study was to examine the effect of secondhand smoking on neurogenic, endothelium- and cGMP-dependent relaxant responses of rabbit corpus cavernosum smooth muscle. Our second goal was to determine whether such an effect can be prevented by oral administration of L-arginine. Male New Zealand rabbi...
journal_title：International journal of impotence research
pub_type： 杂志文章
doi：10.1038/sj.ijir.3901341
更新日期：2005-09-01 00:00:00
abstract：:The authors created the glans penis augmentation by injectable hyaluronic acid gel and reported the 6-month result for premature ejaculation. In a total of 38 patients, long-term effects of 5 years were compared to those of 6 months in terms of residual volume of implants and efficacy on premature ejaculation. Maximal...
journal_title：International journal of impotence research
pub_type： 杂志文章
doi：10.1038/ijir.2008.26
更新日期：2008-07-01 00:00:00
abstract：:Inflatable penile prosthesis (IPP) is an effective treatment for erectile dysfunction refractory to nonsurgical management. The infrapubic approach for IPP placement is less frequently employed than the penoscrotal approach, with only about 25% of IPPs placed via this method. Underutilization of the infrapubic method ...
journal_title：International journal of impotence research
pub_type： 杂志文章,评审
doi：10.1038/s41443-019-0193-0
更新日期：2020-01-01 00:00:00
abstract：:Hypogonadotropic patients may visit pediatricians, general practitioners, endocrinologists or urologists, presenting with microphallus, cryptochidism or pubertas tarda and delayed bone maturation. Congenital hypogonadotropic hypogonadism is characterized, apart from small testes, by the constellation of low serum leve...
journal_title：International journal of impotence research
pub_type： 杂志文章
doi：10.1038/sj.ijir.3900493
更新日期：2000-04-01 00:00:00
