Using the Timed Up & Go test in a clinical setting to predict falling in Parkinson's disease.

Abstract:

OBJECTIVE:To investigate the ability of the Timed Up & Go test to identify patients with Parkinson's disease at risk for a fall. DESIGN:Cross-sectional cohort study. SETTING:Sixteen participating National Parkinson's Foundation Centers of Excellence. PARTICIPANTS:A query yielded a total of 2985 records (1828 men and 1157 women). From these, 884 were excluded because of a lack of crucial information (age, diagnosis, presence of deep brain stimulation, disease duration, inability of performing the Timed Up & Go test without assistance) at the time of testing, leaving 2097 patients included in the analysis. INTERVENTIONS:Not applicable. MAIN OUTCOME MEASURES:The primary outcome measure for this study was falls. The chief independent variable was the Timed Up & Go test. RESULTS:The initial model examined the prediction of falls from the Timed Up & Go test, adjusting for all study covariates. The estimated models in the imputed data sets represented a significant improvement above chance (χ(2) range [df=17], 531.29-542.39, P<.001), suggesting that 74% of participants were accurately classified as a faller or nonfaller. The secondary model in which the question of whether the effect of Timed Up & Go test was invariant across disease severity demonstrated 75% of participants were accurately classified as a faller or nonfaller. Additional analysis revealed a proposed cut score of 11.5 seconds for discrimination of those who did or did not fall. CONCLUSIONS:The findings suggest that the Timed Up & Go test may be an accurate assessment tool to identify those at risk for falls.

journal_name

Arch Phys Med Rehabil

authors

Nocera JR,Stegemöller EL,Malaty IA,Okun MS,Marsiske M,Hass CJ,National Parkinson Foundation Quality Improvement Initiative Investigators.

doi

10.1016/j.apmr.2013.02.020

subject

Has Abstract

pub_date

2013-07-01 00:00:00

pages

1300-5

issue

7

eissn

0003-9993

issn

1532-821X

pii

S0003-9993(13)00199-8

journal_volume

94

pub_type

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