Alterations of corticostriatal plasticity by ammonium and rescue by green tea polyphenols.

abstract：:Bovine collateral ligament synthesized a 35S-labeled large proteoglycan species which eluted with a Kav of approximately 0.27 on Sepharose CL-2B and contained only chondroitin sulfate chains with a molecular mass of approximately 32 kDa. Fluorography of the 35S-labeled core proteins derived from the large ligament pro...

journal_title：Archives of biochemistry and biophysics

authors： Campbell MA,Tester AM,Handley CJ,Checkley GJ,Chow GL,Cant AE,Winter AD,Cain WE

更新日期：1996-05-15 00:00:00

abstract：:Methionine is an essential amino acid for both prokaryotic and eukaryotic organisms; however, little is known concerning its utilization in African trypanosomes, protozoa of the Trypanosoma brucei group. This study explored the Michaelis-Menten kinetic constants for transport and pool formation as well as metabolic ut...

journal_title：Archives of biochemistry and biophysics

authors： Goldberg B,Rattendi D,Lloyd D,Yarlett N,Bacchi CJ

更新日期：2000-05-01 00:00:00

abstract：:The multifunctional tyrosine N-hydroxylase, cytochrome P450TYR (CYP79), from Sorghum bicolor catalyzing the conversion of tyrosine to p-hydroxyphenyl-acetaldoxime in the biosynthesis of the cyanogenic glucoside dhurrin, has been expressed in Escherichia coli using the isopropyl-beta-D-thiogalactopyranoside-inducible v...

journal_title：Archives of biochemistry and biophysics

authors： Halkier BA,Nielsen HL,Koch B,Møller BL

更新日期：1995-10-01 00:00:00

abstract：:Immunological cross-reactivities between isolated subunits of the scorpion Androctonus australis (Aa) and of the horseshoe crab Limulus polyphemus (Lp) hemocyanins were studied using subunit-specific antibodies prepared through immunoadsorption to pure immobilized subunits. Rocket immunoelectrophoreses of the various ...

journal_title：Archives of biochemistry and biophysics

authors： Lamy J,Compin S,Lamy JN

更新日期：1983-06-01 00:00:00

abstract：:TDP-43 is a nuclear protein whose abnormal aggregates are implicated in ALS and FTLD. Recently, an Asn/Gln rich C-terminal segment of TDP-43 has been shown to produce aggregation in vitro and reproduce most of the protein's pathological hallmarks in cells, but little is known about this segment's structure. Here, CD a...

journal_title：Archives of biochemistry and biophysics

authors： Mompeán M,Buratti E,Guarnaccia C,Brito RM,Chakrabartty A,Baralle FE,Laurents DV

更新日期：2014-03-01 00:00:00

abstract：:Liver mitochondria provided with an oxidizable substrate, ATP, oxygen, and an ADP-generating system (soluble F1-ATPase) were used to reevaluate the rate-controlling step(s) intrinsic to all of the processes of mitochondrial oxidative phosphorylation. The quantity termed "control strength" (C), previously defined as th...

journal_title：Archives of biochemistry and biophysics

authors： Davis EJ,Davis-Van Thienen WI

更新日期：1984-09-01 00:00:00

abstract：:The cellular environment is crowded with different kinds of molecules with varying sizes, shapes and compositions. Most of the experiments studying the nature and behaviour of a protein have been done on the isolated protein in dilute buffer solutions which actually do not imitate the in vivo situation. To understand ...

journal_title：Archives of biochemistry and biophysics

authors： Shahid S,Ahmad F,Hassan MI,Islam A

更新日期：2015-10-15 00:00:00

abstract：:The effects of temperature on the initial velocity kinetics of allosteric ATP sulfurylase from Penicillium chrysogenum were measured. The experiments were prompted by the structural similarity between the C-terminal regulatory domain of fungal ATP sulfurylase and fungal APS kinase, a homodimer that undergoes a tempera...

journal_title：Archives of biochemistry and biophysics

authors： Medina DC,Hanna E,MacRae IJ,Fisher AJ,Segel IH

更新日期：2001-09-01 00:00:00

abstract：:Mucus hypersecretion is a common feature in chronic airway diseases, and serine proteases play a critical role in this process. However, the mechanisms by which serine proteases induce mucin5AC hypersecretion have not been fully explored. In this study, we characterized human airway trypsin-like protease (HAT), a seri...

journal_title：Archives of biochemistry and biophysics

authors： Liu C,Li Q,Zhou X,Kolosov VP,Perelman JM

更新日期：2013-07-15 00:00:00

abstract：:The thermodynamics of the drug-inhibitors acyclovir, ganciclovir, and 9-benzylguanine binding to human purine nucleoside phosphorylase (hsPNP) were determined from isothermal titration calorimetry as a function of the substrate phosphate ion (Pi) concentration from 0 to 0.125 M and temperature from 15 degrees C to 35 ...

journal_title：Archives of biochemistry and biophysics

authors： Todorova NA,Schwarz FP

更新日期：2008-12-15 00:00:00

abstract：:The sesquiterpene cyclase, aristolochene synthase, has been purified from Penicillium roqueforti by gel filtration and anion-exchange chromatography. Isolation was facilitated by a change in the elution behavior of the enzyme during gel filtration at different steps in the purification. The purified enzyme had a speci...

journal_title：Archives of biochemistry and biophysics

authors： Hohn TM,Plattner RD

更新日期：1989-07-01 00:00:00

abstract：:Accumulation of carboxymethylated proteins (CML-proteins) is taken as a biomarker of glycoxidative stress which is thought to contribute to the age-related impairment in tissue and cell function. To investigate the occurrence and extent of glycoxidative damage with aging in rat kidney, serum and urine, we have prepare...

journal_title：Archives of biochemistry and biophysics

authors： Hamelin M,Borot-Laloi C,Friguet B,Bakala H

更新日期：2003-03-15 00:00:00

abstract：:Leukotoxin (ltx) and isoleukotoxin (iltx) methyl esters, are metabolites of methyl linoleic acid, an essential fatty acid. They have been associated with acute respiratory distress syndrome. The observed toxicity of ltx and iltx is, in fact, due to the metabolism of the epoxides to their corresponding diols by soluble...

journal_title：Archives of biochemistry and biophysics

authors： Greene JF,Williamson KC,Newman JW,Morisseau C,Hammock BD

更新日期：2000-04-15 00:00:00

abstract：:Isolated adrenocortical carcinoma cells of rat contain alpha 2- and beta-adrenergic receptors. When these cells are incubated with alpha 2-adrenergic agonists, there is a concentration-dependent increase of cyclic GMP that is blocked by the alpha 2-adrenergic antagonist yohimbine but not by the beta-antagonist propran...

journal_title：Archives of biochemistry and biophysics

authors： Jaiswal N,Sharma RK

更新日期：1986-09-01 00:00:00

abstract：:Formation of DNA-protein cross-links between thymine and tyrosine in chromatin of gamma-irradiated or H2O2-treated cultured human cells is reported. Chromatin was isolated from cells, and subsequently hydrolyzed and derivatized. Analysis of derivatized hydrolysates by gas chromatography/mass spectrometry with selected...

journal_title：Archives of biochemistry and biophysics

authors： Olinski R,Nackerdien Z,Dizdaroglu M

更新日期：1992-08-15 00:00:00

abstract：:Oridonin triggers apoptosis of cancer cells and was suggested as anticancer agent. Oridonin is partially effective through mitochondrial depolarization and partially by modifying gene expression. Erythrocytes lack mitochondria and nuclei but may undergo eryptosis, a suicidal cell death characterized by cell shrinkage ...

journal_title：Archives of biochemistry and biophysics

authors： Jilani K,Qadri SM,Zelenak C,Lang F

更新日期：2011-07-01 00:00:00

abstract：:The objective of this study was to elucidate the anti-oxidative roles of coenzyme Q (CoQ) and alpha-tocopherol in mitochondrial membranes by determining whether CoQ directly scavenges peroxyl- and alkoxyl-radicals or indirectly regenerates alpha-tocopherol during autooxidation of mitochondrial membranes. A comparison ...

journal_title：Archives of biochemistry and biophysics

authors： Lass A,Sohal RS

更新日期：1998-04-15 00:00:00

abstract：:Sequence analyses of the C-terminal membrane intercalative region of the rat cytochrome b(5) indicated that this domain has, in addition to a signal sequence, a combined element of the classic stop-transfer sequence typically found in a variety of transmembrane proteins. Such bitopic protein arrangements arise by tand...

journal_title：Archives of biochemistry and biophysics

authors： Kaderbhai MA,Morgan R,Kaderbhai NN

更新日期：2003-04-15 00:00:00

abstract：:Several previously unreported small heat-shock proteins (sHsps) were detected in mitochondria from heat-stressed rat PC12 cells, but not in unstressed controls. Functional inactivation of the mitochondrial sHsps with murine Hsp25 antibody indicated that these sHsps protect NADH:ubiquinone oxidoreductase and NADH dehyd...

journal_title：Archives of biochemistry and biophysics

authors： Downs CA,Jones LR,Heckathorn SA

更新日期：1999-05-15 00:00:00

abstract：:Rat transferrin (rTf), containing one complex glycan, and human transferrin (hTf), containing two complex glycans, were treated with peptide:N-glycosidase F (PNGase) under nondenaturing conditions. Apo rTf with a nonfucosylated standard biantennary glycan, but not its diferric counterpart, yielded satisfactory amounts...

journal_title：Archives of biochemistry and biophysics

authors： Regoeczi E,Bolyos M,Chindemi PA

更新日期：1989-02-01 00:00:00

abstract：:Chlorite dismutase-like proteins are structurally closely related to functional chlorite dismutases which are heme b-dependent oxidoreductases capable of reducing chlorite to chloride with simultaneous production of dioxygen. Chlorite dismutase-like proteins are incapable of performing this reaction and their biologic...

journal_title：Archives of biochemistry and biophysics

authors： Hofbauer S,Hagmüller A,Schaffner I,Mlynek G,Krutzler M,Stadlmayr G,Pirker KF,Obinger C,Daims H,Djinović-Carugo K,Furtmüller PG

更新日期：2015-05-15 00:00:00

abstract：:The kinetics and thermodynamics of Ulex europeas agglutinin 1-H-antigenic determinant was studied by monitoring the binding of the lectin to H-antigenic fucolipid incorporated in liposomes tethered to the sensor surface by surface plasmon resonance. The second-order rate constants for the interactions are several orde...

journal_title：Archives of biochemistry and biophysics

authors： Thomas CJ,Surolia A

更新日期：2000-02-01 00:00:00

abstract：:Recent X-ray crystal structures of human cytochrome P450 2B6 and rabbit cytochrome P450 2B4 in complex with amlodipine showed two bound ligand molecules, one in the active site and one in the substrate access channel. Based on the X-ray crystal structures, we investigated the interactions of P450 2B4 and 2B6 with amlo...

journal_title：Archives of biochemistry and biophysics

authors： Jang HH,Davydov DR,Lee GY,Yun CH,Halpert JR

更新日期：2014-03-01 00:00:00

abstract：:Polyphyllin I (PPI), a bioactive constituent extracted from the rhizomes of Paris polyphylla, is cytotoxic to several cancer types. This study was designed to explore whether PPI prevents non-small-cell lung cancer (NSCLC) growth and to investigate the molecular mechanism. AMP-activated protein kinase (AMPK) has been ...

journal_title：Archives of biochemistry and biophysics

authors： Wu Y,Si Y,Xiang Y,Zhou T,Liu X,Wu M,Li W,Zhang T,Xiang K,Zhang L,Zhao H,Liu Y

更新日期：2020-07-15 00:00:00

abstract：:Methylglyoxal (MGO), a reactive dicarbonyl metabolite is a potent arginine directed glycating agent which has implications for diabetes-related complications. Dicarbonyl metabolites are produced endogenously and in a state of misbalance, they contribute to cell and tissue dysfunction through protein and DNA modificati...

journal_title：Archives of biochemistry and biophysics

authors： Abidi M,Khan MS,Ahmad S,Kausar T,Nayeem SM,Islam S,Ali A,Alam K,Moinuddin

更新日期：2018-05-01 00:00:00

abstract：:FtsZ (Filamentous temperature sensitivity Z) cell division protein from Escherichia coli binds the fluorescence probe DAPI. Bundling of FtsZ was facilitated in the presence of DAPI, and the polymers in solution remained polymerized longer time than the protofilaments formed in the absence of DAPI. DAPI decreased both ...

journal_title：Archives of biochemistry and biophysics

authors： Nova E,Montecinos F,Brunet JE,Lagos R,Monasterio O

更新日期：2007-09-15 00:00:00

abstract：:In a previous study we showed that basic fibroblast growth factor (bFGF) stimulates activation of protein kinase C through phosphoinositide hydrolysis by phospholipase C and phosphatidylcholine hydrolysis by phospholipase D in osteoblast-like MC3T3-E1 cells. In the present study, we investigated whether bFGF stimulate...

journal_title：Archives of biochemistry and biophysics

authors： Kozawa O,Niwa M,Matsuno H,Ishisaki A,Kato K,Uematsu T

更新日期：2001-04-15 00:00:00

abstract：:While prior studies focusing on male mice suggest a role for sterol carrier protein-2/sterol carrier protein-x (SCP-2/SCP-x; DKO) on hepatic phytol metabolism, its role in females is unresolved. This issue was addressed using female and male wild-type (WT) and DKO mice fed a phytoestrogen-free diet without or with 0.5...

journal_title：Archives of biochemistry and biophysics

authors： McIntosh AL,Storey SM,Huang H,Kier AB,Schroeder F

更新日期：2017-12-01 00:00:00

abstract：:Many of the compounds considered for use in pharmaceutical formulations demonstrate incompatibilities with other components at high enough concentrations, including pairs of polymers, polymers and salts, or even proteins in combination with polymers, salts, or other proteins. Freeze concentration can force solutions i...

journal_title：Archives of biochemistry and biophysics

authors： Heller MC,Carpenter JF,Randolph TW

更新日期：1999-03-15 00:00:00

abstract：:A class II Zn(2+)-dependent fructose-1,6-bisphosphate (FBP)- aldolase was purified from an overproducer strain of Escherichia coli and characterized by standard biochemical techniques and 13C NMR spectroscopy. The principal finding of these studies was identification, by 13C NMR spectroscopy, of an enzyme-bound reacti...

journal_title：Archives of biochemistry and biophysics

authors： Szwergold BS,Ugurbil K,Brown TR

更新日期：1995-02-20 00:00:00