Sequence analysis of the nucleocapsid protein gene of the porcine reproductive and respiratory syndrome virus Taiwan MD-001 strain.

Abstract:

:The 3'-portion of the genome from a Taiwan isolate of porcine reproductive and respiratory syndrome (PRRS) virus, strain MD-001, was cloned and sequenced. The resultant 549 nucleotides contained an open reading frame with a coding capacity of 123 amino acids (predicted Mr 13,600). The predicted protein corresponds to the nucleocapsid protein, the gene product of ORF7. Comparative sequence analysis of several known PRRSV strains indicated that this protein showed the highest degree of amino acid similarity to the US VR2332 and the Canadian IAF-Exp91 strains (92.7%) and the least to the Dutch Lelystad strain (56.5%). The phylogenic trees constructed on the basis of the known PRRSV nucleotide sequences indicated that MD-001 strain belongs to the North American strain cluster and that it is distinct from the European virus.

journal_name

Adv Exp Med Biol

authors

Chueh LL,Lee KH,Wang FI,Pang VF,Weng CN

doi

10.1007/978-1-4615-5331-1_103

subject

Has Abstract

pub_date

1998-01-01 00:00:00

pages

795-9

eissn

0065-2598

issn

2214-8019

journal_volume

440

pub_type

杂志文章
  • Oxygen tension measurements using an oxygen polarographic electrode sealed in an implantable silastic tonometer: a new technique.

    abstract::Our new method is comparable to the standard, "open-end" tonometer system and incorporates all its abilities to monitor oxygen tension and perfusion. The new device has the advantage of being completely sealed, providing a true, continuous direct measurement over several days, with freedom of movement for the patient ...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章

    doi:10.1007/978-1-4615-9510-6_31

    authors: Rabkin J,Alena R,Morse J,Goodson WH 3rd,Hunt TK

    更新日期:1988-01-01 00:00:00

  • IL-11Rα: a novel target for the treatment of osteosarcoma.

    abstract::Recent advances have shown that cell surface receptors are expressed differentially in normal and pathological conditions. Novel organ specific and disease specific proteins expressed on tumor vasculature have been identified by in vivo phage display technology and the diversity of the tumor-associated vasculature has...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章,评审

    doi:10.1007/978-3-319-04843-7_15

    authors: Lewis VO

    更新日期:2014-01-01 00:00:00

  • Stem Cell Technology for (Epi)genetic Brain Disorders.

    abstract::Despite the enormous efforts of the scientific community over the years, effective therapeutics for many (epi)genetic brain disorders remain unidentified. The common and persistent failures to translate preclinical findings into clinical success are partially attributed to the limited efficiency of current disease mod...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章,评审

    doi:10.1007/978-3-319-53889-1_23

    authors: Riemens RJM,Soares ES,Esteller M,Delgado-Morales R

    更新日期:2017-01-01 00:00:00

  • Biologically variable respiration as a stochastic process in ventilation - a stochastic model study.

    abstract::Based on the fractal bronchial tree, we introduced a function of "asynchronous phasic contractions of lobular bronchiole", which would generate fluctuations in tidal volumes. Stochastic control theory was able to describe a genesis of biological variability in spontaneous respirations using a Schroedinger wave functio...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章

    doi:10.1007/978-1-4419-5692-7_11

    authors: Min K,Hosoi K,Degami M,Kinoshita Y

    更新日期:2010-01-01 00:00:00

  • Optogenetics-Mediated Gene Therapy for Retinal Diseases.

    abstract::The visual system consists of various types of neurons and a single-nucleotide mutation can sometimes lead to blindness. The phototransduction pathway in the retina starts from the first-order neurons, the photoreceptor cells, and transmits the signals to second-order neurons. Finally, the output signal from third-ord...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章

    doi:10.1007/978-981-15-8763-4_37

    authors: Tomita H,Sugano E

    更新日期:2021-01-01 00:00:00

  • Acceptance of Illness Associates with Better Quality of Life in Patients with Nonmalignant Pulmonary Diseases.

    abstract::Chronic nonmalignant pulmonary diseases impose a heavy burden on patients, generate health-care costs, and contribute to poor health-related quality of life. It has been found that a wide range of factors negatively affects quality of life, but the role of acceptance of illness needs to be further investigated. The ai...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章

    doi:10.1007/5584_2019_386

    authors: Chabowski M,Juzwiszyn J,Bolanowska Z,Brzecka A,Jankowska-Polańska B

    更新日期:2019-01-01 00:00:00

  • Diffusion pathway of oxygen in ox lung.

    abstract::The diffusion coefficients of cell membranes of pneumocytes plus endothelial cells, cytosol plus blood plasma, erythrocyte membranes, and hemoglobin solution in erythrocytes were estimated from the fluorometrically measured membrane viscosity. The time course of oxygen partial pressure distribution was numerically cal...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章

    doi:10.1007/978-1-4615-9510-6_7

    authors: Koyama T,Araiso T

    更新日期:1988-01-01 00:00:00

  • Developmental pathways hijacked by osteosarcoma.

    abstract::Cancer of any type often can be described by an arrest, alteration or disruption in the normal development of a tissue or organ, and understanding of the normal counterpart's development can aid in understanding the malignant state. This is certainly true for osteosarcoma and the normal developmental pathways that gui...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章,评审

    doi:10.1007/978-3-319-04843-7_5

    authors: Mortus JR,Zhang Y,Hughes DP

    更新日期:2014-01-01 00:00:00

  • 12-lipoxygenase expression in human melanoma cell lines.

    abstract::12-lipoxygenase (12-LOX) expression and function in the regulation of the metastatic phenotype was demonstrated in several murine melanoma lines before. Here we have provided novel evidences that, though at a low level (in max. 15% of the cell population), human melanoma lines (HT168, M1, HT199, HT18 and WM35) express...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章

    doi:10.1007/978-1-4615-4793-8_89

    authors: Timár J,Rásó E,Honn KV,Hagmann W

    更新日期:1999-01-01 00:00:00

  • Cellular origin of mucins of the ocular surface tear film.

    abstract::In summary, we have demonstrated that the ocular surface epithelia express at least three mucin genes. We suggest that the gel-forming mucin MUC5AC is a major mucin forming the mucus gel of the tear film. We further suggest that MUC1 facilitates the spread of the MUC5-containing mucus on the ocular surface and, along ...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章,评审

    doi:10.1007/978-1-4615-5359-5_32

    authors: Gipson IK,Inatomi T

    更新日期:1998-01-01 00:00:00

  • Septic-Induced microRNA Expression Modulations Are Linked to Angiogenesis, Vasomotion, and Hypoxia-Induced Processes.

    abstract::Sepsis is an exaggerated immune reaction to an infection, which leads to organ dysfunction especially circulatory failure. This is based on cellular processes, which are regulated by post-transcriptional gene expression modulations including microRNAs (miRNAs). In order to elucidate the role miRNAs play in septic proc...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章

    doi:10.1007/978-3-319-91287-5_36

    authors: Schmidt B,Roessler C,Schumann J

    更新日期:2018-01-01 00:00:00

  • Introduction of new crosslinks into proteins.

    abstract::Analysis of the crosslinks epsilon-(gamma-glutamyl) lysine and epsilon- (beta-aspartyl) lysine present in treated wool has been improved by modifying the enzymic digestion. Treatment of wool with either monocarboxylic acid chlorides in dimethylsulfoxide or with 1-fluoro-2,4-dinitrobenzene in the presence of acetate co...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章

    doi:10.1007/978-1-4684-3282-4_21

    authors: Ziegler K,Schmitz I,Zahn H

    更新日期:1977-01-01 00:00:00

  • Synaptic dysfunction in schizophrenia.

    abstract::Schizophrenia alters basic brain processes of perception, emotion, and judgment to cause hallucinations, delusions, thought disorder, and cognitive deficits. Unlike neurodegeneration diseases that have irreversible neuronal degeneration and death, schizophrenia lacks agreeable pathological hallmarks, which makes it on...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章,评审

    doi:10.1007/978-3-7091-0932-8_22

    authors: Yin DM,Chen YJ,Sathyamurthy A,Xiong WC,Mei L

    更新日期:2012-01-01 00:00:00

  • Trends in Glycolipid Biomarker Discovery in Neurodegenerative Disorders by Mass Spectrometry.

    abstract::Considering the devastating effects of neurodegenerative disorders and the increasing number of people affected by them, an early diagnosis even presymptomatic, prior to serious mental deterioration is necessary. Therefore, screening for biomarkers, especially glycolipids, in the biological matrices, either tissues or...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章,评审

    doi:10.1007/978-3-030-15950-4_42

    authors: Dehelean L,Sarbu M,Petrut A,Zamfir AD

    更新日期:2019-01-01 00:00:00

  • Promoter-associated long noncoding RNAs repress transcription through a RNA binding protein TLS.

    abstract::The majority of the human genome is found to be transcribed and generates mostly noncoding (nc) RNAs that do not possess protein information. MicroRNAs are one of the well-identified small ncRNAs, but occupy merely a fraction of ncRNAs. Long (large) ncRNAs are emerging as a novel class of ncRNAs, but knowledge of thes...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章

    doi:10.1007/978-1-4614-0332-6_12

    authors: Kurokawa R

    更新日期:2011-01-01 00:00:00

  • Factors Influencing the Chaperone-Like Activity of Major Proteins of Mammalian Seminal Plasma, Equine HSP-1/2 and Bovine PDC-109: Effect of Membrane Binding, pH and Ionic Strength.

    abstract::HSP-1/2 and PDC-109 belong to a family of fibronectin type II proteins, present in high concentrations in bovine and equine seminal plasma, respectively. These proteins act as extracellular small heat shock proteins and protect target/client proteins against various kinds of stress. They also exhibit characteristic bi...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章

    doi:10.1007/978-981-13-3065-0_5

    authors: Kumar CS,Singh BP,Alim S,Swamy MJ

    更新日期:2018-01-01 00:00:00

  • Effect of taurine chloramine on differentiation of human preadipocytes into adipocytes.

    abstract::We investigated whether taurine chloramine (TauCl), which is -endogenously produced by immune cells such as macrophages that infiltrate adipose tissue, affects the differentiation of preadipocytes into adipocytes or modulates the expression of adipokines in adipocytes. To study the physiological effects of TauCl on hu...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章

    doi:10.1007/978-1-4614-6130-2_21

    authors: Kim KS,Choi HM,Ji HI,Kim C,Kim JY,Song R,Kim SM,Lee YA,Lee SH,Yang HI,Yoo MC,Hong SJ

    更新日期:2013-01-01 00:00:00

  • Pharmacological targets for pulmonary vascular disease: vasodilation versus anti-remodelling.

    abstract::Two gross mechanisms of pathology are central to pulmonary arterial hypertension - increased pulmonary vascular tone and remodelling of the pulmonary arteries. These pathologies can be caused by a variety of aberrant processes, and combine to cause an increase in pulmonary vascular resistance and consequent right vent...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章,评审

    doi:10.1007/978-1-60761-500-2_31

    authors: Thomas M

    更新日期:2010-01-01 00:00:00

  • Using isolated rat kidney to discover kidney origin biomarkers in urine.

    abstract::The use of targeted proteomics to identify urinary biomarkers of kidney disease in urine can avoid the interference of serum proteins. It may provide better sample throughput, higher sensitivity, and specificity. Knowing which urinary proteins to target is essential for targeted proteomics. In perfusates, there were p...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章

    doi:10.1007/978-94-017-9523-4_17

    authors: Jia L

    更新日期:2015-01-01 00:00:00

  • Headspace volatile aldehydes as indicators of lipid oxidation in foods.

    abstract::Aldehydes are secondary breakdown products of unsaturated lipids. In particular, polyunsaturated lipid fatty acids of the omega-6 and omega-3 families are highly susceptible to oxidation. Using static headspace analysis, the specific aldehyde markers were studied. While linoleic, gamma-linolenic and arachidonic acids ...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章,评审

    doi:10.1007/978-1-4615-1247-9_9

    authors: Shahidi F

    更新日期:2001-01-01 00:00:00

  • Oxygen delivery to and use by primary porcine hepatocytes in the HepatAssist 2000 system for extracorporeal treatment of patients in end-stage liver failure.

    abstract::A system for the extracorporeal treatment of end-stage liver failure patients has been developed and is now in clinical studies. This HepatAssist 2000 system consists of perfusing the plasma of the patient through a hollow-fiber bioreactor containing primary porcine hepatocytes. The goal of the system is to assist the...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章

    doi:10.1007/978-1-4615-4863-8_31

    authors: Custer L,Mullon CJ

    更新日期:1998-01-01 00:00:00

  • Insulin sensitivity, muscle fibre types, and membrane lipids.

    abstract::One of the key abnormalities of non-insulin-dependent diabetes mellitus (NIDDM) and related diseases of the "Metabolic Syndrome" is impaired insulin action (insulin resistance). Since skeletal muscle plays a major role in insulin-stimulated glucose uptake and whole-body energy expenditure, it is a central player in ca...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章,评审

    doi:10.1007/978-1-4899-1928-1_12

    authors: Helge JW,Kriketos AD,Storlien LH

    更新日期:1998-01-01 00:00:00

  • Free flap monitoring in plastic and reconstructive surgery.

    abstract::Free flaps are regularly used in plastic and reconstructive surgery but have a significant failure rate due to vessel thrombosis in the re-established arterial or venous circulation. A monitor of flap perfusion and oxygenation would allow the early detection of progressing flap ischaemia, hastening the required interv...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章

    doi:10.1007/978-1-4615-0075-9_72

    authors: Pickett JA,Thorniley MS,Carver N,Jones DP

    更新日期:2003-01-01 00:00:00

  • HLA-B27-bound peptide repertoires: their nature, origin and pathogenetic relevance.

    abstract::Peptide binding is a central biological property of HLA-B27. The availability of HLA-B27 subtypes differentially associated to ankylosing spondylitis provides a unique tool to explore the relationship between peptide specificity and pathogenetic potential. Many studies have focused on defining the nature of subtype-bo...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章,评审

    doi:10.1007/978-1-4419-0298-6_14

    authors: de Castro JA

    更新日期:2009-01-01 00:00:00

  • The Use of Metformin to Increase the Human Healthspan.

    abstract::Metformin is a safe, effective and useful drug for glucose management in patients with diabetes. However in recent years, more attention has been paid to the possibility of using metformin as an anti-aging drug. It was shown to significantly increase the lifespan in some model organisms and delay the onset of age-asso...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章,评审

    doi:10.1007/978-3-030-42667-5_13

    authors: Piskovatska V,Storey KB,Vaiserman AM,Lushchak O

    更新日期:2020-01-01 00:00:00

  • Identification and characterization of the porcine reproductive and respiratory virus ORFs 7, 5 and 4 products.

    abstract::Porcine reproductive and respiratory syndrome virus (PRRSV) causes abortions and respiratory diseases in pigs. The PRRSV genome is a positive-sense polyadenylated RNA molecule of about 15 kb. Along with the genes for structural proteins (envelope, matrix and nucleocapsid proteins) PRRSV genome contains a number of ORF...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章

    doi:10.1007/978-1-4615-1899-0_51

    authors: Mounir S,Mardassi H,Dea S

    更新日期:1995-01-01 00:00:00

  • The role of mediastinoscopy in the diagnosis of thoracic disease: one-year single center experience.

    abstract::Our experience of using mediastinoscopy for the diagnosis of enlarged mediastinal lymph nodes or mediastinal mass is presented in this study. We reviewed 54 consecutive patients (34 men and 20 women) with mediastinal pathology of varied etiologies who underwent a standard cervical mediastinoscopy from January to Decem...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章

    doi:10.1007/5584_2014_101

    authors: Chabowski M,Szymanska-Chabowska A,Skotarczak J,Janczak D Jr,Pawlowski L,Janczak D

    更新日期:2015-01-01 00:00:00

  • 3D Engineering of Ocular Tissues for Disease Modeling and Drug Testing.

    abstract::The success rate from investigational new drug filing to drug approval has remained low for decades despite major scientific and technological advances, and a steady increase of funding and investment. The failure to demonstrate drug efficacy has been the major reason that drug development does not progress beyond pha...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章

    doi:10.1007/978-3-030-28471-8_7

    authors: Boutin ME,Hampton C,Quinn R,Ferrer M,Song MJ

    更新日期:2019-01-01 00:00:00

  • Mixed function oxidation and intermediary metabolism: metabolic interdependencies in the liver.

    abstract::Both hepatic lipogenesis from glucose and gluconeogenesis from lactate are inhibited by substrates for mixed function oxidation such as aminopyrine. These effects are inducible with phenobarbital pretreatment and absent with a demethylated product of aminopyrine metabolism, aminophenylpyrazolone. The data indicate tha...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章,评审

    doi:10.1007/978-1-4615-9026-2_25

    authors: Thurman RG,Marazzo DP

    更新日期:1975-01-01 00:00:00

  • Gadd45 in stress signaling, cell cycle control, and apoptosis.

    abstract::The first identified Gadd45 gene, Gadd45a, encodes a ubiquitously expressed protein that is often induced by DNA damage and other stress signals associated with growth arrest and apoptosis. This protein and the other two members of this small gene family, Gadd45b and Gadd45g, have been implicated in a variety of the r...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章,评审

    doi:10.1007/978-1-4614-8289-5_1

    authors: Salvador JM,Brown-Clay JD,Fornace AJ Jr

    更新日期:2013-01-01 00:00:00