Cellular origin of mucins of the ocular surface tear film.

Abstract:

:In summary, we have demonstrated that the ocular surface epithelia express at least three mucin genes. We suggest that the gel-forming mucin MUC5AC is a major mucin forming the mucus gel of the tear film. We further suggest that MUC1 facilitates the spread of the MUC5-containing mucus on the ocular surface and, along with the mucus gel, prevents cell and debris adhesion to the ocular surface. The function of MUC4 at the ocular surface remains to be elucidated.

journal_name

Adv Exp Med Biol

authors

Gipson IK,Inatomi T

doi

10.1007/978-1-4615-5359-5_32

subject

Has Abstract

pub_date

1998-01-01 00:00:00

pages

221-7

eissn

0065-2598

issn

2214-8019

journal_volume

438

pub_type

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