Abstract:
OBJECTIVES:To compare tumour enhancement patterns measured using dynamic contrast-enhanced (DCE)-CT with tumour metabolism measured using positron emission tomography (PET)-CT in patients with non-small cell lung cancer (NSCLC) and stable disease after chemotherapy or chemoradiotherapy. METHODS:After treatment, 75 NSCLC tumours in 65 patients who had stable disease on DCE-CT according to Response Evaluation Criteria in Solid Tumour (RECIST) were evaluated using PET-CT. On DCE-CT, relative enhancement ratios (RER) of tumour at 30, 60, 90, 120 s and 5 min after injection of contrast material were measured. Metabolic responses of tumours were classified into two groups according to the maximum standardized uptake value (SUVmax) by PET-CT: complete metabolic response (CR) with an SUVmax of less than 2.5, and noncomplete metabolic response (NR) with an SUVmax of at least 2.5. RESULTS:Using the optimal RER₆₀ cutoff value of 43.7 % to predict NR of tumour gave 95.7 % sensitivity, 64.2 % specificity, and 82.1 % positive and 95.0 % negative predictive values. After adjusting for tumour size, the odds ratio for NR in tumour with an RER60 of at least 43.7 % was 70.85 (95 % CI = 7.95-630.91; P < 0.05). CONCLUSIONS:Even when disease was stable according to RECIST, DCE-CT predicted hypermetabolic status of residual tumour in patients with NSCLC after treatment. KEY POINTS:• Dynamic contrast-enhanced CT (DCE-CT) can provide useful metabolic information about non-small cell lung cancer. • NSCLC lesions, even grossly stable after treatment, show various metabolic states. • DCE-CT enhancement patterns correlate with tumour metabolic status as shown by PET. • DCE-CT helps to assess hypermetabolic NSCLC as stable disease after treatment.
journal_name
Eur Radioljournal_title
European radiologyauthors
Hwang SH,Yoo MR,Park CH,Jeon TJ,Kim SJ,Kim THdoi
10.1007/s00330-012-2755-0subject
Has Abstractpub_date
2013-06-01 00:00:00pages
1573-81issue
6eissn
0938-7994issn
1432-1084journal_volume
23pub_type
杂志文章abstract::To assess the effect of the osmolarity for small bowel distension in MRI, ten volunteers ingested at two separate occasions negative oral contrast agents with different quantity and osmolarity: (1) a water solution combined with 2.0% sorbitol and 0.2% locus bean gum (LBG) with a quantity of 1500 ml and an osmolarity o...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-005-2711-3
更新日期:2005-07-01 00:00:00
abstract::The aim of our study was to determine the frequency of different hepatic arterial variants identified on abdominal CT angiography (CTA) with a 64-row CT system and a high resolution protocol. A total of 250 consecutive abdominal CTAs performed on a 64-row CT system were evaluated. Two radiologists in consensus analyze...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-009-1458-7
更新日期:2009-11-01 00:00:00
abstract:OBJECTIVES:To apply an easy-to-assemble phantom substitute for human prostates in T2-weighted magnetic resonance imaging (T2WI), diffusion-weighted imaging (DWI) and 3D magnetic resonance spectroscopy (MRS). METHODS:Kiwi fruit were fixed with gel hot and cold compress packs on two plastic nursery pots, separated by a ...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-016-4706-7
更新日期:2017-08-01 00:00:00
abstract:OBJECTIVES:To compare radiation doses in cone beam computed tomography (CBCT) with those of multi-detector computed tomography (MDCT) using manufacturers' standard protocols. METHODS:Dose-levels in head and abdominal imaging were evaluated using a dosimetric phantom. Effective dose estimates were performed by placing ...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-013-2934-7
更新日期:2013-11-01 00:00:00
abstract:OBJECTIVE:To assess the radiation dose received by the radiologist when performing wire localisation for axillary radio-isotope sentinel node imaging-guided biopsy in patients with impalpable breast cancers treated with breast-preserving excision. When wire placement follows radio-isotope sentinel node imaging (RSNI) t...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-009-1594-0
更新日期:2010-03-01 00:00:00
abstract::The purpose of this study was to evaluate the reproducibility of CT-volumetric tumour response assessment of pulmonary metastasis using variable volume change thresholds (VCT) and target lesions with response evaluation criteria in solid tumours (RECIST). Fifty consecutive patients with pulmonary metastases undergoing...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-007-0642-x
更新日期:2007-10-01 00:00:00
abstract:OBJECTIVES:The current gold standard in the assessment of lateral intracranial dural arteriovenous fistulas (LDAVF) is digital subtraction angiography (DSA). However, magnetic resonance imaging (MRI) is a non-invasive emerging tool for the evaluation of such lesions. The aim of our study was to compare the DSA to our 3...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-016-4335-1
更新日期:2016-12-01 00:00:00
abstract::In the evaluation of ischemic heart disease only MR imaging seems to have the potential to assess myocardial perfusion, function, and coronary morphology on a single instrument. The aim of this study was to assess the feasibility of a stress test with dipyridamole (0. 56 mg/kg) to analyze myocardial perfusion by Gd fi...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s003300050238
更新日期:1997-01-01 00:00:00
abstract::The magnetic resonance (MR) guidance of endovascular interventions is probably one of the greatest challenges of clinical MR research. MR angiography is not only an imaging tool for the vasculature but can also simultaneously depict high tissue contrast, including the differentiation of the vascular wall and perivascu...
journal_title:European radiology
pub_type: 杂志文章,评审
doi:10.1007/s00330-007-0818-4
更新日期:2008-04-01 00:00:00
abstract:OBJECTIVES:To assess long-term prognosis after low-dose 64-slice coronary computed tomography angiography (CCTA) using prospective electrocardiogram-triggering. METHODS:We included 434 consecutive patients with suspected or known coronary artery disease referred for low-dose CCTA. Patients were classified as normal, w...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-017-4849-1
更新日期:2017-11-01 00:00:00
abstract:OBJECTIVES:To compare a multi-feature-based radiomic biomarker with volumetric analysis in discriminating lung adenocarcinomas with different disease-specific survival on computed tomography (CT) scans. METHODS:This retrospective study obtained institutional review board approval and was Health Insurance Portability a...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-017-4855-3
更新日期:2017-11-01 00:00:00
abstract:OBJECTIVES:To review the gadoxetic acid disodium (EOB)-enhanced magnetic resonance (MR) imaging features of cholangiolocellular carcinoma (CoCC) of the liver and compare them with those of hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma (ICC). METHODS:EOB-enhanced MR images of 19 patients with CoCC,...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-017-4811-2
更新日期:2017-11-01 00:00:00
abstract:OBJECTIVES:To evaluate tissue perfusion and venous susceptibility in ischaemic stroke patients as a means to predict clinical status and early prognosis. METHODS:A retrospective study of 51 ischaemic stroke patients were enrolled in this study. Susceptibility, perfusion and National Institute of Health stroke scale (N...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-016-4593-y
更新日期:2017-06-01 00:00:00
abstract:OBJECTIVES:To compare the significance of the two-compartment model, considering diffusional anisotropy with conventional diffusion analyzing methods regarding the detection of occult changes in normal-appearing white matter (NAWM) of multiple sclerosis (MS). METHODS:Diffusion-weighted images (nine b-values with six d...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-014-3572-4
更新日期:2015-06-01 00:00:00
abstract::There is little published long-term survival data for patients with colorectal liver metastases treated with radiofrequency ablation (RFA). We present a multivariate analysis of 5-year survival in 309 patients (198 male, aged 64 (24-92)) treated at 617 sessions. Our standard protocol used internally cooled electrodes ...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-008-1258-5
更新日期:2009-05-01 00:00:00
abstract::Epiploic appendicitis and segmental omentum infarction are considered to be rare conditions, which may mimic an abdominal surgical emergency. The purpose of our study was to describe clinical findings, US and CT appearance of infarction of an epiploic appendage and omentum, and to determine their epidemiological chara...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s003300050942
更新日期:1999-01-01 00:00:00
abstract::The purpose of this study was to compare LV function and mass quantification derived from cardiac dual-source CT (DSCT) exams with those obtained by MRI in heart transplant recipients. Twelve heart transplant recipients who underwent cardiac DSCT and MRI examination were included. Double-oblique short-axis 8-mm slice ...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-008-0949-2
更新日期:2008-09-01 00:00:00
abstract::Positron emission tomography (PET) is a powerful molecular imaging technique for the human body-imaging applications currently available. As altered glucose metabolism is characteristic for many malignancies, FDG-PET is mostly used in oncology for staging and therapy control. Although PET is a sensitive tool for detec...
journal_title:European radiology
pub_type: 杂志文章,评审
doi:10.1007/s00330-005-0088-y
更新日期:2006-05-01 00:00:00
abstract:OBJECTIVE:Coronary angiography using multidetector computed tomography (MDCT) allows non-invasive assessment of non-calcified, calcified and mixed plaques. Progression of coronary plaques may be influenced by statins. METHODS:Sixty-three consecutive patients underwent MDCT as a follow-up to their original CT angiograp...
journal_title:European radiology
pub_type: 临床试验,杂志文章
doi:10.1007/s00330-010-1880-x
更新日期:2010-12-01 00:00:00
abstract:OBJECTIVES:Contrast media (CM) extravasation is a well-known complication of CT angiography (CTA). Our prospective randomized control study aimed to assess whether a four-phasic CM administration protocol reduces the risk of extravasation compared to the routinely used three-phasic protocol in coronary CTA. METHODS:Pa...
journal_title:European radiology
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00330-017-4866-0
更新日期:2017-11-01 00:00:00
abstract:OBJECTIVE:It is controversial to adopt non-invasive diagnostic criteria of hepatocellular carcinoma (HCC) in subcentimeter lesions. This study was aimed to define the optimal noninvasive diagnostic criteria of subcentimeter HCC and to evaluate the effect on tumor staging. METHODS:We included 110 treatment-naïve patien...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-020-07329-z
更新日期:2020-10-12 00:00:00
abstract:PURPOSE:To evaluate in vivo T2 mapping as quantitative, imaging-based biomarker for meniscal degeneration in humans, by studying the correlation between T2 relaxation time and degree of histological degeneration as reference standard. METHODS:In this prospective validation study, 13 menisci from seven patients with ra...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-019-06091-1
更新日期:2019-10-01 00:00:00
abstract::The rectum has become the most successful area of the gastrointestinal tract to be studied with MRI. Its anatomical location, fixed in the pelvic fat, and its lack of peristalsis, make it an ideal organ to be scanned with MRI. In addition, MRI allows a direct sagittal and coronal display, of key importance to colorect...
journal_title:European radiology
pub_type: 杂志文章,评审
doi:10.1007/s003300050328
更新日期:1998-01-01 00:00:00
abstract:OBJECTIVE:To test a digital imaging X-ray device based on the direct capture of X-ray photons with pixel detectors, which are coupled with photon-counting readout electronics. METHODS:The chip consists of a matrix of 256 × 256 pixels with a pixel pitch of 55 μm. A monolithic image of 11.2 cm × 7 cm was obtained by the...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-011-2246-8
更新日期:2012-01-01 00:00:00
abstract:PURPOSE:To evaluate magnetic resonance imaging (MRI) for diaphragmatic endometriosis diagnosis. MATERIALS AND METHODS:Over a 2-year period, all diaphragmatic MRI performed in the context of diaphragmatic endometriosis were reviewed. Axial and coronal fat-suppressed T1- and T2-weighted sequences were analyzed by two in...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-016-4226-5
更新日期:2016-11-01 00:00:00
abstract::The safety of the non-ionic contrast medium iopentol (Imagopaque, Nycomed Imaging AS, Oslo, Norway) when used in cerebral angiography and aortic arch angiography, was the focus of this investigation. Overall quality of visualization and changes in heart rate and blood pressure were, however, also assessed. In total, 3...
journal_title:European radiology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1007/pl00006884
更新日期:1997-01-01 00:00:00
abstract::Systemic mastocytosis (SM) is an abnormal proliferation of mast cells, located in different structures: skin, bone marrow, spleen, liver and lymph nodes. Magnetic resonance imaging was prospectively performed in ten patients diagnosed by bone marrow biopsy in order to describe the different patterns of bone marrow inv...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s003300050796
更新日期:1999-01-01 00:00:00
abstract:OBJECTIVES:This study aimed to evaluate automated breast ultrasound (ABUS) compared to hand-held traditional ultrasound (HHUS) in the visualisation and BIRADS characterisation of breast lesions. MATERIALS AND METHODS:From January 2016 to January 2017, 1,886 women with breast density category C or D (aged 48.6±10.8 yea...
journal_title:European radiology
pub_type: 杂志文章,多中心研究
doi:10.1007/s00330-017-5011-9
更新日期:2018-02-01 00:00:00
abstract::The aim of this study was to determine apparent diffusion coefficients (ADCs) of focal liver lesions on the basis of a respiratory triggered diffusion-weighted single-shot echo-planar MR imaging sequence (DW-SS-EPI) and to evaluate whether ADC measurements can be used to characterize lesions. One hundred and two patie...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-007-0785-9
更新日期:2008-03-01 00:00:00
abstract:OBJECTIVES:To compare 0.15 mmol/kg gadobutrol for late gadolinium enhancement (LGE) imaging of chronic myocardial infarction with a relaxivity-adjusted dose of gadoterate meglumine (Gd-DOTA). METHODS:Seventeen patients with suspected chronic myocardial infarction underwent LGE imaging at 1.5 T, acquiring an inversion-...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-012-2563-6
更新日期:2013-01-01 00:00:00