Abstract:
:Cross-linked dextran and polymethylmethacrylate mixture (Lipen-10) is newly developed tissue filler. The purpose of this study was to evaluate tolerability and efficacy of Lipen-10 on penile enhancement. Twenty adult males were included in this study. Lipen-10 was injected into the subcutaneous tissue of the penile shaft. The penile girth and length were measured in the flaccid state, before and 1, 3 and 6 months after the injection. The circumference increased by 3.7±1.2 cm (50.8%, P<0.0001) at penile base, 4.2±0.9 cm (59.0%, P<0.001) at mid-shaft, and 3.8±1.0 cm (53.2%, P<0.0001) at distal shaft and the length increased by 2.3±1.4 cm (63.2%, P<0.001). There was, however, no significant difference between 3 and 6 months post-treatment in girth and length (P-values: 0.796, 0.498, 0.600 and 0.084 for penile base, mid- and distal-shaft and length, respectively). The complications were only one mild asymmetry of penile shape and one 5-mm-sized nodule in the injected site. There were no clinically significant adverse events in all subjects. Penile injection of Lipen-10 led to a significant increase in penile size, showed a good durability and was well-tolerated, without serious adverse events. These results suggest that penile injection of Lipen-10 may be a new effective method for penile enhancement.
journal_name
Int J Impot Resjournal_title
International journal of impotence researchauthors
Yang DY,Lee WK,Kim SCdoi
10.1038/ijir.2012.41subject
Has Abstractpub_date
2013-05-01 00:00:00pages
99-103issue
3eissn
0955-9930issn
1476-5489pii
ijir201241journal_volume
25pub_type
杂志文章abstract::At this present time there is a serious gap in our understanding of how psychological difficulties result in specific sexual dysfunction. In this paper, a theoretical model of sexual response is proposed which involves the parallel existence of excitatory and inhibitory mechanisms in the central nervous system. Eviden...
journal_title:International journal of impotence research
pub_type: 杂志文章,评审
doi:
更新日期:1998-05-01 00:00:00
abstract::Defining the minimal clinically meaningful improvement (MCMI) is crucial to understanding the treatment effects on health-status measures. We estimated the MCMI on the quality of erection questionnaire (QEQ), a validated measure specific to assess erectile quality during sexual intercourse. Data were from two controll...
journal_title:International journal of impotence research
pub_type: 杂志文章,随机对照试验
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abstract::The frequency of sexual dysfunction (SD) is not very well known in patients with chronic hepatitis C. In this study, the prevalence of SD and its correlations with psychological and biological variables was assessed in 46 HCV positive patients. The mean age of patients was 46.4+/-9.4 y; the mean duration of HCV infect...
journal_title:International journal of impotence research
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abstract::The diagnosis and classification of female sexual disorders has undergone significant changes over the last fifty years as a function of changing societal expectations for female sexual conduct, available knowledge about sexual psychophysiology and actual clinical practice. Currently, female sexual disorders are conce...
journal_title:International journal of impotence research
pub_type: 杂志文章,评审
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更新日期:1998-05-01 00:00:00
abstract::The objective of this study was to investigate the predictive validity of the Dutch translation of the Golombok Rust Inventory of Sexual Satisfaction (GRISS) for the presence of clinically relevant sexual dysfunctions and patient's need of help. A total of 57 male urological outpatients (age 50.7+/-13.2 y; range 27-77...
journal_title:International journal of impotence research
pub_type: 杂志文章
doi:10.1038/sj.ijir.3900966
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abstract::Venous insufficiency of the corpora cavernosa is the second most common cause of erectile dysfunction (ED). A functional insufficiency of the venous system has been hypothesised, but the cause is still unclear. To evaluate a possible endocrine mechanism, we have studied hormone profile in a group of nine patients with...
journal_title:International journal of impotence research
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doi:10.1038/sj.ijir.3901287
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journal_title:International journal of impotence research
pub_type: 杂志文章
doi:10.1038/ijir.2017.24
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journal_title:International journal of impotence research
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doi:10.1038/sj.ijir.3901217
更新日期:2004-04-01 00:00:00
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journal_title:International journal of impotence research
pub_type: 杂志文章
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journal_title:International journal of impotence research
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journal_title:International journal of impotence research
pub_type: 杂志文章
doi:10.1038/ijir.2013.8
更新日期:2013-09-01 00:00:00
abstract::We describe a case of gunshot wound to the corpora cavernosa caused by a low-velocity bullet in a 43-year-old man. He volunteered that his lover's husband shot him with a handgun. The bullet had penetrated the right gluteal region with no exit wound causing a right corpus cavernosum lesion. A penile colour-duplex dopp...
journal_title:International journal of impotence research
pub_type: 杂志文章
doi:10.1038/sj.ijir.3901472
更新日期:2006-11-01 00:00:00
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journal_title:International journal of impotence research
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journal_title:International journal of impotence research
pub_type: 杂志文章
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更新日期:2002-12-01 00:00:00
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journal_title:International journal of impotence research
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doi:
更新日期:1995-09-01 00:00:00
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journal_title:International journal of impotence research
pub_type: 杂志文章
doi:10.1038/ijir.2009.17
更新日期:2009-09-01 00:00:00
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journal_title:International journal of impotence research
pub_type: 杂志文章,评审
doi:10.1038/sj.ijir.3900567
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journal_title:International journal of impotence research
pub_type: 杂志文章
doi:10.1038/ijir.2011.10
更新日期:2011-05-01 00:00:00
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journal_title:International journal of impotence research
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journal_title:International journal of impotence research
pub_type: 杂志文章
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更新日期:2020-09-01 00:00:00
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journal_title:International journal of impotence research
pub_type: 临床试验,杂志文章
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journal_title:International journal of impotence research
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pub_type: 杂志文章
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更新日期:2004-02-01 00:00:00
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journal_title:International journal of impotence research
pub_type: 杂志文章,随机对照试验
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更新日期:2007-03-01 00:00:00
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journal_title:International journal of impotence research
pub_type: 杂志文章
doi:10.1038/sj.ijir.3900823
更新日期:2002-04-01 00:00:00