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Effects of phonophoresis of piroxicam and ultrasound on symptomatic knee osteoarthritis.

Abstract：

OBJECTIVE:To compare the effects of phonophoresis of piroxicam (PhP) and ultrasound therapy (UT) in patients with mild to moderate, symptomatic knee osteoarthritis (OA). DESIGN:A randomized, double-blind, controlled trial. SETTING:Department of rehabilitation medicine, university hospital. PARTICIPANTS:Patients with knee OA (N=46; mean age ± SD, 58.91±10.50y) who had visual analog scale (VAS) scores of 50 to 92mm (mean, 71.5mm) for knee pain intensity and Kellgren-Lawrence grades of I to III were randomly allocated into 2 groups: PhP and UT (23 in each group). INTERVENTIONS:Both the PhP and UT groups were treated with an ultrasound program using the stroking technique, continuous mode, 1.0W/cm(2), 10 minutes per session, and 5 times per week for 2 weeks. Four grams of 0.5% piroxicam gel (20mg of piroxicam drug) was used in the PhP group, while the nondrug coupling gel was used in the UT group. MAIN OUTCOME MEASURES:A 100-mm VAS for usual pain and the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) were evaluated before and after treatment in both groups using a double-blinded procedure. RESULTS:The VAS and total WOMAC scores were significantly improved after treatment in both groups (P<.001). The PhP group showed more significant effects than the UT group, both in reducing the VAS pain score (P=.009) and in improving the WOMAC score, although it did not reach the level of significance (P=.143). CONCLUSIONS:Our results indicated that PhP was significantly more effective than UT in reducing pain and tended to improve knee functioning in Kellgren-Lawrence grades I to III knee OA. PhP is suggested as a new, effective method for treatment of symptomatic knee OA.

journal_name

Arch Phys Med Rehabil

journal_title

Archives of physical medicine and rehabilitation

authors

Luksurapan W,Boonhong J

doi

10.1016/j.apmr.2012.09.025

subject

Has Abstract

pub_date

2013-02-01 00:00:00

pages

250-5

issue

2

eissn

0003-9993

issn

1532-821X

pii

S0003-9993(12)01000-3

journal_volume

94

pub_type

杂志文章,随机对照试验

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