Abstract：
OBJECTIVES:To determine whether slow gait represents a compensatory strategy to reduce the energetic cost of walking with age. DESIGN:Cross-sectional analysis. SETTING:Community-dwelling volunteers from the Baltimore Longitudinal Study of Aging (BLSA). PARTICIPANTS:Four hundred twenty community-dwelling persons aged 32 to 96 (mean 68.1 ± 12.5) who underwent a physical examination, physical function testing, and energy expenditure assessment. MEASUREMENTS:Energy expenditure per minute (mL/kg/min) and per meter (mL/kg/m) during 2.5 minutes of overground walking at customary speed and usual gait speed over 6 m (m/s) were examined. General linear regression models were used to assess the relationship between customary walking energy expenditure and usual gait speed, adjusted for potential confounders including smoking, medical diagnoses, walking-related pain, and balance difficulty. RESULTS:Usual gait speed was slower with increasing age after age 65. Energy expenditure per minute during customary walking averaged 13.0 ± 2.8 mL/kg/min and was independent of age (ρ < 0.01, P = .88). In contrast, energy expenditure per meter walked was progressively higher after age 65 (ρ = 0.35, P < .001) and heightened after age 80 (r = 0.57, P < .001), mirroring the observed pattern of usual gait speed. This relationship remained significant after adjusting for multiple impairments and comorbidities. CONCLUSION:These observations support the hypothesis that slower gait at older ages may reflect a compensatory action to offset the greater energetic cost of walking associated with aging and chronic conditions. Future studies should evaluate the specific mechanisms that contribute to this phenomenon as novel targets for clinical intervention.
journal_name
J Am Geriatr Socjournal_title
Journal of the American Geriatrics Societyauthors
Schrack JA,Simonsick EM,Chaves PH,Ferrucci Ldoi
10.1111/j.1532-5415.2012.04153.xsubject
Has Abstractpub_date
2012-10-01 00:00:00pages
1811-6issue
10eissn
0002-8614issn
1532-5415journal_volume
60pub_type
杂志文章abstract：OBJECTIVES:To estimate the prevalence of self-harm, suicidal ideation (SI), and suicide attempts (SA) in older adults in the emergency department (ED), including differences according to age, sex, and race and ethnicity. DESIGN:Quasi-experimental, multiphase, eight-center study with prospective review of consecutive c...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章,多中心研究
doi：10.1111/jgs.14529
更新日期：2016-10-01 00:00:00
abstract：OBJECTIVES:To examine the relationship between frequent falls in older drivers and motor vehicle collision (MVC) involvement. DESIGN:Cross-sectional. SETTING:North central Alabama. PARTICIPANTS:Population-based sample of 2,000 licensed drivers aged 70 and older. MEASUREMENTS:Self-reported history of falling two or ...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/jgs.12594
更新日期：2014-01-01 00:00:00
abstract：OBJECTIVES:Poor diet due to poor oral health was proposed as a potential mediator of the association between poor oral health and frailty. This study explores the cross-sectional associations between poor oral health, poor diet, and frailty in Canadian adults, aged 45 to 85 years, and then tests whether the expected or...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/jgs.16377
更新日期：2020-05-01 00:00:00
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journal_title：Journal of the American Geriatrics Society
pub_type： 评论,杂志文章
doi：10.1046/j.1532-5415.2002.50418.x
更新日期：2002-09-01 00:00:00
abstract：OBJECTIVES:To assess the frequency of diagnostic errors in older adults presenting to the emergency department (ED) with symptoms suggestive of Chikungunya virus infection (CVI) and to compare the rates of misdiagnosis of older and younger adults. DESIGN:Cross-sectional study performed in the University Hospitals of M...
journal_title：Journal of the American Geriatrics Society
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doi：10.1111/jgs.15492
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journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.1982.tb03364.x
更新日期：1982-12-01 00:00:00
abstract：:The relationship between atrial natriuretic peptide (ANP) and age was studied. In elderly subjects (65 to 84 years) higher basal ANP levels were found as compared with those found in young subjects (21 to 23 years). Volume loading (750 mL 0.9% NaCl in 60 minutes) increased ANP levels only in the aged group, and plasma...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.1990.tb01502.x
更新日期：1990-11-01 00:00:00
abstract：OBJECTIVES:To describe the prevalence of visual and auditory impairment in frail older persons and to evaluate the association between sensory impairment and overall functional status. DESIGN:Prospective patient evaluation and retrospective analysis of data. SETTING:The outpatient geriatric assessment clinic of a uni...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.1999.tb07432.x
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更新日期：2020-08-01 00:00:00
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doi：10.1111/jgs.13346
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journal_title：Journal of the American Geriatrics Society
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doi：10.1046/j.1532-5415.2001.4911234.x
更新日期：2001-11-01 00:00:00
abstract：OBJECTIVES:To determine the prognostic value of apathy for mortality in patients of somatic (SC) and dementia special care (DSC) nursing home (NH) units. DESIGN:Longitudinal design, secondary analyses of a 2-year, cluster-randomized trial with six measurements, approximately 4 months in between. SETTING:SC and DSC-un...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1111/jgs.15007
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pub_type： 杂志文章
doi：10.1111/j.1532-5415.2011.03661.x
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journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.2000.tb05003.x
更新日期：2000-05-01 00:00:00
abstract：OBJECTIVES:To determine whether metabolic syndrome is an independent predictor of decline in mobility in an elderly community sample. DESIGN:Biracial community-based prospective cohort study. SETTING:Urban and rural areas of central North Carolina. PARTICIPANTS:One thousand two hundred twenty-nine older African Amer...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.2005.00607.x
更新日期：2006-03-01 00:00:00
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journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章,多中心研究
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更新日期：2012-03-01 00:00:00
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doi：10.1111/j.1532-5415.2000.tb04786.x
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pub_type： 杂志文章
doi：10.1111/j.1532-5415.1988.tb03433.x
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更新日期：2005-01-01 00:00:00
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journal_title：Journal of the American Geriatrics Society
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更新日期：2014-10-01 00:00:00
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更新日期：2014-12-01 00:00:00
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journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
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更新日期：2009-09-01 00:00:00
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pub_type： 临床试验,杂志文章,随机对照试验
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更新日期：1991-02-01 00:00:00
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journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章,评审
doi：10.1111/j.1532-5415.1966.tb03069.x
更新日期：1966-05-01 00:00:00
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journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.1997.tb01470.x
更新日期：1997-06-01 00:00:00
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journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.1996.tb04065.x
更新日期：1996-12-01 00:00:00
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journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
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更新日期：2001-04-01 00:00:00
abstract：OBJECTIVES:The purpose of this study was to determine if reported nighttime sleep problems and daytime sleepiness were associated with reported falling during the previous 12 months in a representatively sampled older adult population. DESIGN:Random-digit dial telephone survey. SETTING:Representatively sampled older ...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.2000.tb02596.x
更新日期：2000-10-01 00:00:00
