The biology of aging.

abstract：OBJECTIVES:To determine the trajectory of handgrip strength (HGS) from age 70 to 90 and its association with mood, cognition, functional status, and mortality. DESIGN:Prospective follow-up of an age-homogenous representative community-dwelling cohort (born 1920-21) in the Jerusalem Longitudinal Cohort Study (1990-2015...

journal_title：Journal of the American Geriatrics Society

authors： Stessman J,Rottenberg Y,Fischer M,Hammerman-Rozenberg A,Jacobs JM

更新日期：2017-03-01 00:00:00

abstract：OBJECTIVES:To compare the longitudinal changes in maximal aerobic capacity (VO2max) in healthy middle aged and older athletes and sedentary men. DESIGN:A cohort study with mean follow-up of 8.7 years (range 4.0-12.8). SETTING:Outpatient research at a tertiary hospital. PARTICIPANTS:Forty-two healthy, middle aged, an...

journal_title：Journal of the American Geriatrics Society

authors： Katzel LI,Sorkin JD,Fleg JL

更新日期：2001-12-01 00:00:00

abstract：OBJECTIVES:To compare clinical and economic outcomes of early insulin initiation with those of delayed initiation in older adults with type 2 diabetes mellitus (T2DM). DESIGN:Retrospective cohort study. SETTING:Humana Medicare Advantage health insurance plan. PARTICIPANTS:Older (≥65) Medicare beneficiaries with T2DM...

journal_title：Journal of the American Geriatrics Society

authors： Bhattacharya R,Zhou S,Wei W,Ajmera M,Sambamoorthi U

更新日期：2015-05-01 00:00:00

abstract：:Two concurrent studies of geriatric outpatients who received diagnoses of depression were conducted. In the first, patients were treated with one of two tricyclic antidepressants or with a placebo. In the second, patients were assigned to groups receiving either psychodynamic group therapy or cognitive-behavioral grou...

journal_title：Journal of the American Geriatrics Society

authors： Jarvik LF,Mintz J,Steuer J,Gerner R

更新日期：1982-11-01 00:00:00

abstract：:A study was made of 50 patients drawn at random from a Skilled Nursing Facility (SNF) attended by seven physicians. For 59 percent of these patients, polypharmacy was practiced but no substantiating diagnoses were recorded. Approximately half of the drugs were administered pro re nata. More drugs were prescribed in po...

journal_title：Journal of the American Geriatrics Society

authors： Segal JL,Thompson JF,Floyd RA

更新日期：1979-03-01 00:00:00

abstract：:A case is presented of primary endolymphatic stromal sarcoma of the uterus in a debilitated elderly patient. Surgical intervention was contraindicated. Radium therapy was unsuccessful. A 4-month course of treatment with doxorubicin (Adriamycin) resulted in disappearance of the tumor. The patient is living 19 months af...

journal_title：Journal of the American Geriatrics Society

authors： Adducci JE

更新日期：1976-10-01 00:00:00

abstract：OBJECTIVES:To compare the cognitive profile of a population representative sample with orthostatic hypotension (OH) with the profile of a sample without. DESIGN:Cross-sectional analysis of a prospective nationally representative population study. SETTING:The Irish Longitudinal Study on Ageing (TILDA). PARTICIPANTS:T...

journal_title：Journal of the American Geriatrics Society

authors： Frewen J,Savva GM,Boyle G,Finucane C,Kenny RA

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVES:To measure end-of-life (EOL) care preferences and advance care planning (ACP) in older Latinos and to examine the relationship between culture-based attitudes and extent of ACP. DESIGN:Cross-sectional interview. SETTING:Twenty-two senior centers in greater Los Angeles. PARTICIPANTS:One hundred forty-seven...

journal_title：Journal of the American Geriatrics Society

authors： Kelley AS,Wenger NS,Sarkisian CA

更新日期：2010-06-01 00:00:00

abstract：:Despite the fact that there is a high prevalence of depression among the elderly, little research on the efficacy of psychotherapy or pharmacotherapy with the elderly has been reported in the literature. This paper describes a sample of 18 elderly patients who received both psychotherapy and pharmacotherapy for the tr...

journal_title：Journal of the American Geriatrics Society

authors： Rothblum ED,Sholomskas AJ,Berry C,Prusoff BA

更新日期：1982-11-01 00:00:00

abstract：OBJECTIVES:To compare the trajectories of motor and cognitive decline in older adults who progress to dementia with the trajectories of those who do not. To evaluate the added value of measuring motor and cognitive decline longitudinally versus cross-sectionally for predicting dementia. DESIGN:Prospective cohort study...

journal_title：Journal of the American Geriatrics Society

authors： Montero-Odasso M,Speechley M,Muir-Hunter SW,Sarquis-Adamson Y,Sposato LA,Hachinski V,Borrie M,Wells J,Black A,Sejdić E,Bherer L,Chertkow H,Canadian Gait and Cognition Network.

更新日期：2018-09-01 00:00:00

abstract：:The contribution of frailty to human morbidity and mortality is immense. Yet it lacks a conceptual framework. By borrowing from the hypotheses provided by the thermophysicists, frailty can be understood in a way that both interrelates the relationship between form and function and provides medical science with an oper...

journal_title：Journal of the American Geriatrics Society

authors： Bortz WM 2nd

更新日期：1993-09-01 00:00:00

abstract：:The benefits of prophylactic aspirin therapy to prevent cardiovascular and cerebrovascular disease in asymptomatic individuals remains unclear. The rationale for developing a multicentered, double-blind, placebo-controlled clinical trial to determine whether low-dose aspirin (100 mg daily) prevents cardiovascular and ...

journal_title：Journal of the American Geriatrics Society

authors： Silagy CA,McNeil JJ,Bulpitt CJ,Donnan GA,Tonkin AM,Worsam B

更新日期：1991-05-01 00:00:00

abstract：OBJECTIVE:The study describes the prevalence of medical nursing home practice. Further, it examines the extent to which physician characteristics and local county health care resources predict nursing home involvement. This information is relevant to evaluating and devising strategies that address the future provision ...

journal_title：Journal of the American Geriatrics Society

authors： Katz PR,Karuza J,Kolassa J,Hutson A

更新日期：1997-08-01 00:00:00

abstract：:Available strategies to increase influenza vaccination rates in the elderly have not been tested in the private sector where most elderly receive care. We performed a randomized controlled trial of a postcard reminder in the three private general internal medicine practices. The observed vaccination rates of 55% in ex...

journal_title：Journal of the American Geriatrics Society

authors： Buchner DM,Larson EB,White RF

更新日期：1987-08-01 00:00:00

abstract：OBJECTIVE:To examine the effect of vitamin B12 deficiency on older veterans and its relationship to general health and cognitive impairment. DESIGN:Cross-sectional study. SETTING:Oklahoma City Veterans Affairs Medical Center. PARTICIPANTS:Data for this research were obtained from 303 ambulatory, older veterans who u...

journal_title：Journal of the American Geriatrics Society

authors： Bernard MA,Nakonezny PA,Kashner TM

更新日期：1998-10-01 00:00:00

abstract：OBJECTIVES:To compare the cost-effectiveness of four influenza vaccines available in the United States for persons aged 65 and older: trivalent inactivated influenza vaccine (IIV3), quadrivalent inactivated influenza vaccine (IIV4), a more-expensive high-dose IIV3, and a newly approved adjuvanted IIV3. DESIGN:Cost-eff...

journal_title：Journal of the American Geriatrics Society

authors： Raviotta JM,Smith KJ,DePasse J,Brown ST,Shim E,Nowalk MP,Zimmerman RK

更新日期：2016-10-01 00:00:00

abstract：:Catechol-O-methyltransferase (COMT) inhibitors are a new therapeutic option in the treatment of patients with Parkinson's disease. COMT inhibitors act by extending the duration of action of levodopa, thus improving the amount of time a patient can experience benefit from levodopa. COMT inhibitors are only used in conj...

journal_title：Journal of the American Geriatrics Society

authors： Waters C

更新日期：2000-06-01 00:00:00

abstract：:This study involved a 1st generation of 194 aged residents at the Philadelphia Geriatric Center plus 2nd and 3rd generations of 357 and 306 offspring, respectively. Serum cholesterol levels (including type of abnormality) and triglyceride levels were determined. The results suggest that hyperlipidemia at all ages is r...

journal_title：Journal of the American Geriatrics Society

authors： Woldow A

更新日期：1975-11-01 00:00:00

abstract：:Generalist physicians provide most primary care for older people. Increasingly, undergraduate clinical education occurs in community sites. Hence, community-based generalist faculty members need continuing education in geriatrics to support clinical practice and teaching. The Geriatrics Scholars Program provided conti...

journal_title：Journal of the American Geriatrics Society

authors： Willett RM,Boling PA,Meyers ME,Hoban JD,Lawson SR,Schlesinger JB

更新日期：2007-02-01 00:00:00

abstract：OBJECTIVES:To explore and deepen understanding of factors influencing driving exposure for older drivers. DESIGN:Cross-sectional. SETTING:Baseline data on function and driving exposure from 1 week of driving were evaluated. PARTICIPANTS:A convenience sample of 380 drivers aged 75 and older, residing in northwest Syd...

journal_title：Journal of the American Geriatrics Society

authors： Coxon K,Chevalier A,Lo S,Ivers R,Brown J,Keay L

更新日期：2015-06-01 00:00:00

abstract：OBJECTIVE:Validation of a new instrument for screening dementia, the Cross Cultural Cognitive Examination (CCCE), is described. DESIGN:Criterion and concurrent validation and cross-cultural comparison of a new instrument. PARTICIPANTS:All individuals over the age of 40 in a village in southern Guam participated in a ...

journal_title：Journal of the American Geriatrics Society

authors： Glosser G,Wolfe N,Albert ML,Lavine L,Steele JC,Calne DB,Schoenberg BS

更新日期：1993-09-01 00:00:00

abstract：:The GRECC program was established by the VA in 1975 and has been expanded since then to 16 sites. For more than a decade, GRECC staff have made major contributions to advancing the understanding of the aging process and developing approaches that have improved the care of older veterans as well as all frail elderly pe...

journal_title：Journal of the American Geriatrics Society

authors： Goodwin M,Morley JE

更新日期：1994-09-01 00:00:00

abstract：:The second heart sound was studied by phonocardiography and carotid tracings in 103 elderly subjects without overt evidence of heart disease. Their ages ranged from 60 to 99 years. A normal type of splitting was found in 55.3%, and a single sound in 41.7%. The difference between these percentages and those found in 60...

journal_title：Journal of the American Geriatrics Society

authors： Luisada AA,Knighten V,Rao DB

更新日期：1977-08-01 00:00:00

abstract：OBJECTIVE:To assess the satisfaction of surrogate decision-makers with the decision to place feeding tubes in elderly patients with impaired decision-making capacity. DESIGN:Inception cohort followed for 5 weeks. SETTING:Four hospitals in the greater Los Angeles area. PARTICIPANTS:Fifty-eight surrogate decision-make...

journal_title：Journal of the American Geriatrics Society

authors： McNabney MK,Beers MH,Siebens H

更新日期：1994-02-01 00:00:00

abstract：OBJECTIVES:To evaluate whether levels of cognitive reserve (CR), as measured using the Wechsler Adult Intelligence Scale (WAIS)-III vocabulary test, moderated longitudinal associations between cognitive functions and decline in gait speed in a community-based cohort of older adults without dementia, specifically, wheth...

journal_title：Journal of the American Geriatrics Society

authors： Holtzer R,Wang C,Lipton R,Verghese J

更新日期：2012-11-01 00:00:00

abstract：OBJECTIVES:Only limited data are available regarding smoking and health in later life and, in particular, in the older Chinese population. This paper reports the relationship between smoking and mortality in a Chinese cohort aged 70 years and older. SETTING:A population-based study conducted in Hong Kong. PARTICIPANT...

journal_title：Journal of the American Geriatrics Society

authors： Ho SC,Zhan SY,Tang JL,Chan SG,Woo J

更新日期：1999-12-01 00:00:00

abstract：:After a one-year interval, a structured interview designed to assess the quality of life was again conducted with most of the tenants in a single-room occupancy hotel in New York City. Comparisons was made between the two sets of findings. During the year, a program had been in effect to provide social, psychiatric, r...

journal_title：Journal of the American Geriatrics Society

authors： Plutchik R,McCarthy M,Hall BH

更新日期：1975-06-01 00:00:00

abstract：OBJECTIVES:To determine whether mean leukocyte telomere length (LTL) serves as a biomarker of disability assessed according to activities of daily living (ADLs) and what factors may modify this relationship. DESIGN:Retrospective cross-sectional study. SETTING:A subset of the National Long Term Care Survey (NTLCS), a ...

journal_title：Journal of the American Geriatrics Society

authors： Risques RA,Arbeev KG,Yashin AI,Ukraintseva SV,Martin GM,Rabinovitch PS,Oshima J

更新日期：2010-07-01 00:00:00

abstract：OBJECTIVES:To evaluate and summarize the evidence of muscle weakness as a risk factor for falls in older adults. DESIGN:Random-effects meta-analysis. SETTING:English-language studies indexed in MEDLINE and CINAHL (1985-2002) under the key words aged and accidental falls and risk factors; bibliographies of retrieved p...

journal_title：Journal of the American Geriatrics Society

authors： Moreland JD,Richardson JA,Goldsmith CH,Clase CM

更新日期：2004-07-01 00:00:00

abstract：OBJECTIVES:To evaluate the effect of nine disabling medical conditions upon recovery from functional limitations by elders. DESIGN:Retrospective analysis of prospective longitudinal cohort. SETTING:Community. PARTICIPANTS:Persons aged 65 and older in Framingham Heart Study. MEASUREMENTS:Change in function in elders...

journal_title：Journal of the American Geriatrics Society

authors： Miller RR,Zhang Y,Silliman RA,Hayes MK,Leveille SG,Murabito JM,Kiel D,O'Connor GT,Felson DT

更新日期：2004-02-01 00:00:00