Emerging antidementia drugs: a preliminary ethical view.

abstract：OBJECTIVE:To determine whether serum thyrotropin (TSH) levels are altered in euthyroid older persons compared with middle-aged adults. DESIGN:Serum TSH and thyroid hormone levels were measured in a large group of older persons (> 70 years old, n = 216) and their middle-aged offspring (40-60 years old, n = 211) after e...

journal_title：Journal of the American Geriatrics Society

authors： Hershman JM,Pekary AE,Berg L,Solomon DH,Sawin CT

更新日期：1993-08-01 00:00:00

abstract：:The field has progressed to the point where a genetic investigation of the aging processes in Drosophila can be viewed as constituting both a serious and a feasible research program. There now exists at least one single gene mutant which yields an accelerated aging phenotype, at least two single gene null mutants affe...

journal_title：Journal of the American Geriatrics Society

authors： Arking R,Dudas SP

更新日期：1989-08-01 00:00:00

abstract：:The 143 physicians who returned to Temple University Medical School a questionnaire on knowledge of prescribing for the elderly constituted 25% of a stratified random sample of general practitioners (GPs), family practitioners (FPs), and practitioners in internal medicine (IMs) reimbursed under Medicare in Pennsylvani...

journal_title：Journal of the American Geriatrics Society

authors： Ferry ME,Lamy PP,Becker LA

更新日期：1985-09-01 00:00:00

abstract：:As many as 50% of people satisfying diagnostic criteria for dementia are undiagnosed. A team-based training program for dementia screening and management was developed targeting four professions (medicine, nursing, pharmacy, social work) whose scope of practice involves dementia care. An interprofessional group of 10 ...

journal_title：Journal of the American Geriatrics Society

authors： Tan ZS,Damron-Rodriguez J,Cadogan M,Gans D,Price RM,Merkin SS,Jennings L,Schickedanz H,Shimomura S,Osterweil D,Chodosh J

更新日期：2017-01-01 00:00:00

abstract：OBJECTIVES:To determine the effect of cataract surgery on the occurrence of falls and mobility and balance problems in older adults with cataract. DESIGN:Longitudinal follow-up study. SETTING:Clinical Research Unit, University of Alabama at Birmingham. PARTICIPANTS:Persons aged 55 and older with a cataract were recr...

journal_title：Journal of the American Geriatrics Society

authors： McGwin G Jr,Gewant HD,Modjarrad K,Hall TA,Owsley C

更新日期：2006-07-01 00:00:00

abstract：OBJECTIVES:To analyze the association between chronic kidney disease (CKD) and mild cognitive impairment (MCI) in Mexican Americans and to determine whether there is a blood-based proteomic profile linking CKD to MCI. DESIGN:Retrospective analysis of cohort study. SETTING:Health and Aging Brain among Latino Elders st...

journal_title：Journal of the American Geriatrics Society

authors： Szerlip HM,Edwards ML,Williams BJ,Johnson LA,Vintimilla RM,O'Bryant SE

更新日期：2015-10-01 00:00:00

abstract：:The effect of age on glucose tolerance, insulin secretion, and in vivo insulin action (insulin clamp) was studied in 48 nonobese subjects, all of whom were fully ambulatory and in good general health. The observed age-related increase in fasting plasma glucose (r = 0.35, P less than 0.01) was not due to an increase in...

journal_title：Journal of the American Geriatrics Society

authors： Rosenthal M,Doberne L,Greenfield M,Widstrom A,Reaven GM

更新日期：1982-09-01 00:00:00

abstract：OBJECTIVES:Determine the relationship between a broad array of structure and process elements of nursing home care and (a) resident infection and (b) hospitalization for infection. DESIGN:Baseline data were collected from September 1992 through March 1995, and residents were followed for 2 years; facility data were co...

journal_title：Journal of the American Geriatrics Society

authors： Zimmerman S,Gruber-Baldini AL,Hebel JR,Sloane PD,Magaziner J

更新日期：2002-12-01 00:00:00

abstract：OBJECTIVE:To evaluate the use of pentoxifylline to treat impotence in men with mild to moderate penile vascular insufficiency. DESIGN:Double-blind randomized clinical trial. SETTING:Sexual Dysfunction Clinic at VA Medical Center, Sepulveda, CA. PARTICIPANTS:Convenience sample of couples. INTERVENTION:Twelve weeks o...

journal_title：Journal of the American Geriatrics Society

authors： Korenman SG,Viosca SP

更新日期：1993-04-01 00:00:00

abstract：BACKGROUND:The need for mentorship in aging research among postdoctoral trainees and junior faculty across medical disciplines and subspecialties is increasing, yet senior personnel with expertise in aging are lacking to fulfill the traditional dyadic mentorship role. Facilitated peer mentorship is grounded in collabor...

journal_title：Journal of the American Geriatrics Society

authors： Masterson Creber RM,Baldwin MR,Brown PJ,Rao MK,Goyal P,Hummel S,Dodson JA,Helmke S,Maurer MS

更新日期：2019-04-01 00:00:00

abstract：OBJECTIVE:To evaluate the use of influenza vaccine, rapid influenza testing, and influenza antiviral medication in nursing homes in the US to prevent and control outbreaks. METHODS:Survey questionnaires were sent to 1017 randomly selected nursing homes in nine states. Information was collected on influenza prevention,...

journal_title：Journal of the American Geriatrics Society

authors： Zadeh MM,Buxton Bridges C,Thompson WW,Arden NH,Fukuda K

更新日期：2000-10-01 00:00:00

abstract：OBJECTIVES:Many elderly persons have drug benefits with coverage gaps, such as in Medicare Part D. Because beneficiaries who have such gaps must pay all drug costs, an accurate knowledge of gap thresholds and communication with providers about exceeding caps is important for elderly persons to manage out-of-pocket drug...

journal_title：Journal of the American Geriatrics Society

authors： Tseng CW,Dudley RA,Brook RH,Keeler E,Hixon AL,Manlucu LR,Mangione CM

更新日期：2009-05-01 00:00:00

abstract：:The objectives of this study were to examine the prevalence of assistive technology (AT) use, type of assistance used for each activity of daily living (ADL) limitation, and correlates of AT use among Native Indian aged 55 and older. Data were collected as part of a cross-sectional study of disability with 505 members...

journal_title：Journal of the American Geriatrics Society

authors： Goins RT,Spencer SM,Goli S,Rogers JC

更新日期：2010-11-01 00:00:00

abstract：:The Geriatric Pharmacy elective course at the University of Kentucky College of Pharmacy uses a simulated medication adherence project to increase awareness of adherence concerns facing older adults who take multiple medications. This study evaluated the effect of this project. Students enrolled in this 3-credit hour ...

journal_title：Journal of the American Geriatrics Society

authors： Divine HS,Cain J

更新日期：2009-08-01 00:00:00

abstract：OBJECTIVES:To compare longitudinal changes in healthcare costs between fallers admitted to the hospital at the time of the fall (admitted), those not admitted to the hospital (nonadmitted), and nonfaller controls; test hypotheses related to differences in mean costs between and within these groups over time; and estima...

journal_title：Journal of the American Geriatrics Society

authors： Bohl AA,Fishman PA,Ciol MA,Williams B,Logerfo J,Phelan EA

更新日期：2010-05-01 00:00:00

abstract：OBJECTIVES:To examine loss of community-dwelling status 9 months after hospitalization for high-acuity emergency general surgery (HA-EGS) disease among older Americans. DESIGN:Retrospective analysis of claims data. SETTING:US communities with Medicare beneficiaries. PARTICIPANTS:Medicare beneficiaries age 65 years o...

journal_title：Journal of the American Geriatrics Society

authors： Smith JW,Knight Davis J,Quatman-Yates CC,Waterman BL,Strassels SA,Wong JD,Heh VK,Baselice HE,Brock GN,Clark BC,Bridges JFP,Santry HP

更新日期：2019-11-01 00:00:00

abstract：OBJECTIVES:To determine whether obese older adults who qualify for nursing home (NH) placement are as likely as nonobese adults to be admitted to NHs that provide adequate quality of care. DESIGN:Retrospective study. SETTING:NHs in New York State. PARTICIPANTS:Individuals aged 65 and older newly admitted to a NH in ...

journal_title：Journal of the American Geriatrics Society

authors： Zhang N,Rodriguez-Monguio R,Barenberg A,Gurwitz J

更新日期：2016-05-01 00:00:00

abstract：OBJECTIVES:To assess older urban women's knowledge about sexual transmission of human immunodeficiency virus (HIV)/acquired immune deficiency syndrome (AIDS) and to evaluate the relationship between their HIV/AIDS knowledge level and sources of information. DESIGN:Cross-sectional survey conducted between June 2001 and...

journal_title：Journal of the American Geriatrics Society

authors： Henderson SJ,Bernstein LB,George DM,Doyle JP,Paranjape AS,Corbie-Smith G

更新日期：2004-09-01 00:00:00

abstract：OBJECTIVES:To determine the association between self-reported sleep and nap habits and mortality in a large cohort of older women. DESIGN:Study of Osteoporotic Fractures prospective cohort study. SETTING:Four communities within the United States. PARTICIPANTS:Eight thousand one hundred one Caucasian women aged 69 an...

journal_title：Journal of the American Geriatrics Society

authors： Stone KL,Ewing SK,Ancoli-Israel S,Ensrud KE,Redline S,Bauer DC,Cauley JA,Hillier TA,Cummings SR

更新日期：2009-04-01 00:00:00

abstract：OBJECTIVES:To determine the effects of a medicated chewing gum on the oral health of frail older people. DESIGN:A controlled, double-blind trial using three groups based on random allocation of residential homes. SETTING:Sixteen residential homes in West Hertfordshire, England. PARTICIPANTS:One hundred eleven dentat...

journal_title：Journal of the American Geriatrics Society

authors： Simons D,Brailsford SR,Kidd EA,Beighton D

更新日期：2002-08-01 00:00:00

abstract：OBJECTIVES:To describe the types of continence aids that older adults hospitalized in acute medical units use and to test the association between use of continence aids and development of new urinary incontinence (UI) at discharge. DESIGN:Prospective cohort study. SETTING:A 900-bed teaching hospital in Israel. PARTI...

journal_title：Journal of the American Geriatrics Society

authors： Zisberg A,Sinoff G,Gur-Yaish N,Admi H,Shadmi E

更新日期：2011-06-01 00:00:00

abstract：OBJECTIVES:The purpose of this study was to test whether an intervention combining increased daytime physical activity with improvement in the nighttime environment improves sleep and decreases agitation in nursing home residents. DESIGN:A randomized trial. SETTING:One community nursing home in the Los Angeles, Calif...

journal_title：Journal of the American Geriatrics Society

authors： Alessi CA,Yoon EJ,Schnelle JF,Al-Samarrai NR,Cruise PA

更新日期：1999-07-01 00:00:00

abstract：BACKGROUND:A widely held dictum in aging research is that heterogeneity in health increases with age, but the basis for this claim has not been fully investigated. We examined heterogeneity at different ages across health characteristics to describe variation and trends; we investigated the comparative importance of be...

journal_title：Journal of the American Geriatrics Society

authors： Nguyen QD,Moodie EM,Forget MF,Desmarais P,Keezer MR,Wolfson C

更新日期：2020-11-05 00:00:00

abstract：OBJECTIVES:To examine the clinical characteristics, motor impairments, and drug treatments of nursing home residents with Parkinson's disease (PD). DESIGN:Cross-sectional study. SETTING:Nursing homes in the southeast of the Netherlands. PARTICIPANTS:Nursing home residents with PD and a Mini-Mental State Examination ...

journal_title：Journal of the American Geriatrics Society

authors： Weerkamp NJ,Zuidema SU,Tissingh G,Poels PJ,Munneke M,Koopmans RT,Bloem BR

更新日期：2012-12-01 00:00:00

abstract：OBJECTIVE:This study was conducted to determine the incidence of long bone fractures in institutionalized older persons and to describe preceding traumatic events and the functional status of individuals sustaining fractures. DESIGN:A 1-year, prospective, cumulative incidence survey. SETTING:Eleven skilled nursing ca...

journal_title：Journal of the American Geriatrics Society

authors： Kane RS,Burns EA,Goodwin JS

更新日期：1995-02-01 00:00:00

abstract：OBJECTIVES:To determine whether there may be a common mechanism resulting in global sensory impairment of the five classical senses (vision, smell, hearing, touch, and taste) in older adults. DESIGN:Representative, population-based study. SETTING:National Social Life, Health, and Aging Project. PARTICIPANTS:Communit...

journal_title：Journal of the American Geriatrics Society

authors： Correia C,Lopez KJ,Wroblewski KE,Huisingh-Scheetz M,Kern DW,Chen RC,Schumm LP,Dale W,McClintock MK,Pinto JM

更新日期：2016-02-01 00:00:00

abstract：:An operational definition of frailty is important for clinical care, research, and policy planning. The literature on the clinical definitions, screening tools, and severity measures of frailty were systematically reviewed as part of the Canadian Initiative on Frailty and Aging. Searches of MEDLINE from 1997 to 2009 w...

journal_title：Journal of the American Geriatrics Society

authors： Sternberg SA,Wershof Schwartz A,Karunananthan S,Bergman H,Mark Clarfield A

更新日期：2011-11-01 00:00:00

abstract：OBJECTIVE:To examine changes in functional status over time by age, gender, and ethnicity in a representative sample of older persons. DESIGN:Six-year prospective cohort study. SETTING:Alameda County, California. PARTICIPANTS:508 persons 65 years old and older at baseline in 1984. MAIN OUTCOME MEASURES:Activities o...

journal_title：Journal of the American Geriatrics Society

authors： Strawbridge WJ,Kaplan GA,Camacho T,Cohen RD

更新日期：1992-08-01 00:00:00

abstract：BACKGROUND:Cross-sectional associations have been found between frail individuals and worse white matter (WM) integrity. However, the prospective association between WM integrity and frailty is still unclear. Our objectives were to measure associations between WM integrity using diffusion tensor imaging (DTI) and the 5...

journal_title：Journal of the American Geriatrics Society

authors： Maltais M,de Souto Barreto P,Perus L,Mangin JF,Grigis A,Chupin M,Bouyahia A,Gabelle A,Delrieux J,Rolland Y,Vellas B,Multidomain Alzheimer Preventive Trial\/Data Sharing Alzheimer (MAPT\/DSA) Study Group.

更新日期：2020-05-01 00:00:00

abstract：OBJECTIVES:To describe the prevalence of visual and auditory impairment in frail older persons and to evaluate the association between sensory impairment and overall functional status. DESIGN:Prospective patient evaluation and retrospective analysis of data. SETTING:The outpatient geriatric assessment clinic of a uni...

journal_title：Journal of the American Geriatrics Society

authors： Keller BK,Morton JL,Thomas VS,Potter JF

更新日期：1999-11-01 00:00:00