Abstract:
:The presence of vitamin D receptors in diverse tissues like immune cells, beta-cells in the pancreas, and cardiac myocytes has prompted research to evaluate the impact of vitamin D deficiency on the occurrence of immune diseases, diabetes, and cardiovascular disease (CVD). The expression of receptors not only in normal cells, but also in cancer cells including breast, prostate, and colon cancer cells has moreover opened the path to therapeutic exploitation of vitamin D or its metabolites and hypocalcemic structural analogues as pharmaceutical tools in the fight against chronic non-communicable diseases like diabetes, CVD, and cancer.
journal_name
Endocrinol Metab Clin North Amjournal_title
Endocrinology and metabolism clinics of North Americaauthors
Wolden-Kirk H,Gysemans C,Verstuyf A,Mathieu Cdoi
10.1016/j.ecl.2012.05.004subject
Has Abstractpub_date
2012-09-01 00:00:00pages
571-94issue
3eissn
0889-8529issn
1558-4410pii
S0889-8529(12)00070-9journal_volume
41pub_type
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