当前位置： SCI文献检索 > NEUROTOXICOLOGY期刊下所有文献 > Decision rules for assessment of chronic solvent-induced encephalopathy: Results in 2370 patients.

Decision rules for assessment of chronic solvent-induced encephalopathy: Results in 2370 patients.

Abstract：

:For the diagnosis of patients suspected of chronic solvent-induced encephalopathy (CSE), it would be helpful if the applied cognitive tests show a characteristic profile of impairment in this disease. We investigated the existence of such a profile. In 1997-2006 two expert teams in The Netherlands systematically examined 2370 patients referred for evaluation of suspected CSE. The procedure included two selection steps: (1) intake interview, using criteria of exposure, development of symptoms and absence of non-solvent causes, and (2) seven tests of the computerized Neurobehavioural Evaluation System (NES). Patients showing negligible impairments were considered free from CSE and were not further examined. The third step comprised a neuropsychological, neurological and exposure evaluation. Explicit decision rules for the diagnosis of CSE were developed, including a minimum score for cognitive impairment summarizing 25 cognitive tests. These rules were retroactively applied to 563 patients, comprising 513 patients who had regularly completed all diagnostic steps and a sample of 50 out of the approximately 450 patients with negligible impairments on the NES, who were fully examined. The data from this sample were extrapolated to the original number of 450. In the combined population of 963 patients, a calculated 301 patients were given the diagnosis 'Solely CSE', 242 'CSE and other disease', 158 'Other Disease' and 262 'No (known) disease'. In the Solely CSE patients, the most impaired tests regarded Verbal Fluency & -Similarities, Motor Speed and Simple Attention. A profile of test results that might support the identification of patients with CSE amongst the other referred patients, was not found. The diverging results of related cognitive tests indicate that the use of a core test battery is needed to improve comparability. We consider the decision rules as a step towards a more objective assessment of CSE.

journal_name

Neurotoxicology

journal_title

Neurotoxicology

authors

Verberk MM,van der Hoek JA,van Valen E,Wekking EM,van Hout MS,Hageman G,van der Laan G,van Dijk FJ

doi

10.1016/j.neuro.2012.06.005

subject

Has Abstract

pub_date

2012-08-01 00:00:00

pages

742-52

issue

4

eissn

0161-813X

issn

1872-9711

pii

S0161-813X(12)00137-4

journal_volume

33

pub_type

杂志文章

相关文献

NEUROTOXICOLOGY文献大全
  • The IPCS Collaborative Study on Neurobehavioral Screening Methods: II. Protocol design and testing procedures.

    abstract：:This paper describes the development of the protocol for the International Programme on Chemical Safety (IPCS)-sponsored Collaborative Study on Neurobehavioral Screening Methods, including background on the methods and chemicals selected, as well as details concerning the conduct of the collaborative study, including ...

    journal_title：Neurotoxicology

    pub_type： 杂志文章,多中心研究

    doi：

    authors： Moser VC,Tilson HA,MacPhail RC,Becking GC,Cuomo V,Frantík E,Kulig BM,Winneke G

    更新日期：1997-01-01 00:00:00

  • Persistent Na+ and K+ channel dysfunctions after chronic exposure to insecticides and pyridostigmine bromide.

    abstract：:Many soldiers that served in the 1991 Gulf War developed widespread chronic pain. Exposure to insecticides and the nerve gas prophylactic pyridostigmine bromide (PB) was identified as risk factors by the Research Advisory Committee on Gulf War Veterans' Illnesses (GWI). We examined whether a 60 day exposure to neuroto...

    journal_title：Neurotoxicology

    pub_type： 杂志文章

    doi：10.1016/j.neuro.2013.08.006

    authors： Nutter TJ,Jiang N,Cooper BY

    更新日期：2013-12-01 00:00:00

  • Prosaptide prevents paclitaxel neurotoxicity.

    abstract：:Paclitaxel (Taxol), a chemotherapeutic agent used to treat breast and ovarian tumors, has been reported to induce a predominantly sensory neuropathy. Co-treatment with neurotrophic factors and paclitaxel has been proposed for preventing or reversing paclitaxel-induced peripheral neuropathy. Prosaposin, the precursor o...

    journal_title：Neurotoxicology

    pub_type： 杂志文章

    doi：

    authors： Campana WM,Eskeland N,Calcutt NA,Misasi R,Myers RR,O'Brien JS

    更新日期：1998-04-01 00:00:00

  • Multiple dose exposure effects on the tissue distribution of lead in the preweanling rat.

    abstract：:The time dependent tissue/organ distribution of Pb resulting from repeated intragastric exposure of the preweanling rat to Pb acetate was investigated. On the day of parturition, 12 dams were assigned randomly either to control (nonhandled) or Pb-treated groups and their litters were culled to 8 pups. On days 6, 9, 12...

    journal_title：Neurotoxicology

    pub_type： 杂志文章

    doi：

    authors： Massaro EJ,Miller GD,Massaro TF

    更新日期：1984-10-01 00:00:00

  • Changes in rat urinary porphyrin profiles predict the magnitude of the neurotoxic effects induced by a mixture of lead, arsenic and manganese.

    abstract：:The neurotoxic metals lead (Pb), arsenic (As) and manganese (Mn) are ubiquitous contaminants occurring as mixtures in environmental settings. The three metals may interfere with enzymes of the heme bioshyntetic pathway, leading to excessive porphyrin accumulation, which per se may trigger neurotoxicity. Given the mult...

    journal_title：Neurotoxicology

    pub_type： 杂志文章

    doi：10.1016/j.neuro.2014.10.009

    authors： Andrade V,Mateus ML,Batoréu MC,Aschner M,Marreilha dos Santos AP

    更新日期：2014-12-01 00:00:00

  • Ammonia at pathophysiologically relevant concentrations activates kynurenic acid synthesis in cultured astrocytes and neurons.

    abstract：:The synthesis of the NMDA receptor glycine site antagonist kynurenic acid (KYNA) from exogenously added kynurenine was measured in cultured cerebral cortical neurons, cortical astrocytes and an oligodendroglial cell line OLN-93, incubated for 2 h in the presence or absence of ammonium acetate ("ammonia") at 0.1-10 mM ...

    journal_title：Neurotoxicology

    pub_type： 杂志文章

    doi：10.1016/j.neuro.2006.01.004

    authors： Wejksza K,Rzeski W,Turski WA,Hilgier W,Dybel A,Albrecht J

    更新日期：2006-07-01 00:00:00

  • Thyroid hormone treatment alleviates the impairments of neurogenesis, mitochondrial biogenesis and memory performance induced by methamphetamine.

    abstract：:Chronic use of methamphetamine (MA), a neurotoxic psychostimulant, leads to long-lasting cognitive dysfunctions in humans and animal models. Thyroid hormones (THs) have several physiological actions and are crucial for normal behavioral, intellectual and neurological development. Considering the importance of THs in t...

    journal_title：Neurotoxicology

    pub_type： 杂志文章

    doi：10.1016/j.neuro.2019.05.003

    authors： Seyedhosseini Tamijani SM,Beirami E,Ahmadiani A,Dargahi L

    更新日期：2019-09-01 00:00:00

  • Domoic acid disrupts the activity and connectivity of neuronal networks in organotypic brain slice cultures.

    abstract：:Domoic acid is a neurotoxin produced by algae and is found in seafood during harmful algal blooms. As a glutamate agonist, domoic acid inappropriately stimulates excitatory activity in neurons. At high doses, this leads to seizures and brain lesions, but it is unclear how lower, asymptomatic exposures disrupt neuronal...

    journal_title：Neurotoxicology

    pub_type： 杂志文章

    doi：10.1016/j.neuro.2016.08.004

    authors： Hiolski EM,Ito S,Beggs JM,Lefebvre KA,Litke AM,Smith DR

    更新日期：2016-09-01 00:00:00

  • The association between neurobehavioral performance and lung function.

    abstract：:This study investigated the relationship between neurobehavioral performance and pulmonary function in young and middle adults. Data were collected from 178 subjects (88 male, 90 female) aged 20-50 years. Neurobehavioral performance was assessed by the Korean version of The Swedish Performance Evaluation System (SPES-...

    journal_title：Neurotoxicology

    pub_type： 杂志文章

    doi：10.1016/j.neuro.2006.03.019

    authors： Min JY,Min KB,Paek D,Sakong J,Cho SI

    更新日期：2007-03-01 00:00:00

  • Lack of functional expression of NMDA receptors in PC12 cells.

    abstract：:PC12 cells are an established model for studying the role of N-methyl-d-aspartate (NMDA) receptors in excitotoxicity and function as multimeric assemblies of NR1 with at least one NR2(A-D) subunit. We examined NR1 splice variant and NR2 subunit expression in four PC12 cell-lines (ATCC, WEHI, Ordway and Flinders), corr...

    journal_title：Neurotoxicology

    pub_type： 杂志文章

    doi：10.1016/j.neuro.2007.04.006

    authors： Edwards MA,Loxley RA,Williams AJ,Connor M,Phillips JK

    更新日期：2007-07-01 00:00:00

  • Brain aluminum in Alzheimer's disease using an improved GFAAS method.

    abstract：:Aluminum (Al) has been determined in autopsy brain samples (20 mg, dry weight) from 10 histologically verified Alzheimer's disease (AD) patients and 10 neurologically normal controls using an improved graphite furnace atomic absorption method. The method makes use of a potassium dichromate matrix modifier to circumven...

    journal_title：Neurotoxicology

    pub_type： 杂志文章

    doi：

    authors： Xu N,Majidi V,Markesbery WR,Ehmann WD

    更新日期：1992-01-01 00:00:00

  • Age-related effects of chlorpyrifos on acetylcholine release in rat brain.

    abstract：:Chlorpyrifos (CPF) is an organophosphorus insecticide that elicits toxicity through inhibition of acetylcholinesterase (AChE). Young animals are markedly more sensitive than adults to the acute toxicity of CPF. We evaluated acetylcholine (ACh) release and its muscarinic receptor-mediated regulation (i.e. muscarinic au...

    journal_title：Neurotoxicology

    pub_type： 杂志文章

    doi：10.1016/s0161-813x(00)00009-7

    authors： Won YK,Liu J,Olivier K Jr,Zheng Q,Pope CN

    更新日期：2001-02-01 00:00:00

  • Ethanol inhibition of reduced frequency-dependent rundown of calcium currents in acutely dissociated MS/nDB neurons from chronic in vivo lead-exposed adult rats.

    abstract：:Although it is well known that lead (Pb2+0 acutely blocks voltage-gated calcium currents (VGCCs) in mammalian neurons, little is known about the long-term effects of continuous exposure to this metal on VGCCs. In the present study, the effects of chronic lead exposure on VGCCs (with barium ions as the charge carrier) ...

    journal_title：Neurotoxicology

    pub_type： 杂志文章

    doi：

    authors： Grover CA,Jasek MC,Frye GD,Griffith WH

    更新日期：1997-01-01 00:00:00

  • Performance alterations associated with occupational exposure to manganese--a meta-analysis.

    abstract：:The review aimed at quantifying the evidence of performance effects resulting from occupational exposure to manganese. Epidemiological studies published between 1987 and 2008 were analyzed. The approach was based on the meta-analytical method of effect size estimates and sought to contribute to the following issues: (...

    journal_title：Neurotoxicology

    pub_type： 杂志文章,meta分析,评审

    doi：10.1016/j.neuro.2009.05.001

    authors： Meyer-Baron M,Knapp G,Schäper M,van Thriel C

    更新日期：2009-07-01 00:00:00

  • Vinblastine and doxorubicin administration to pregnant mice affects brain development and behaviour in the offspring.

    abstract：BACKGROUND:Administration of chemotherapy during the fetal phase of pregnancy may put late-developing organs like the central nervous system at risk. METHODS:Transplacental transfer of doxorubicin and vinblastine was measured in C57/BJ mice by high-performance liquid chromatographic detection of the drugs in maternal ...

    journal_title：Neurotoxicology

    pub_type： 杂志文章

    doi：10.1016/j.neuro.2009.04.009

    authors： Van Calsteren K,Hartmann D,Van Aerschot L,Verbesselt R,Van Bree R,D'Hooge R,Amant F

    更新日期：2009-07-01 00:00:00

  • Impact of gestational and lactational phthalate exposure on hypothalamic content of amino acid neurotransmitters and FSH secretion in peripubertal male rats.

    abstract：:This study investigated the effect of the pre- and perinatal exposure to di-(2-ethylhexyl) phthalate (DEHP) on the neuroendocrine parameters that regulate reproduction in peripubertal male rats. DEHP at dose of 3 and 30mg/kg bw/day was administered orally to female rat since pregnancy onset until weaning. The male lit...

    journal_title：Neurotoxicology

    pub_type： 杂志文章

    doi：10.1016/j.neuro.2010.06.006

    authors： Carbone S,Szwarcfarb B,Ponzo O,Reynoso R,Cardoso N,Deguiz L,Moguilevsky JA,Scacchi P

    更新日期：2010-12-01 00:00:00

  • Prenatal exposure to the organophosphate pesticide chlorpyrifos and childhood tremor.

    abstract：BACKGROUND:The organophosphate insecticide chlorpyrifos (CPF), widely used for agricultural purposes, has been linked to neurodevelopmental deficits. Possible motor effects at low to moderate levels of exposure have not been evaluated. METHODS:Prenatal exposure to CPF was measured in umbilical cord blood in a sample o...

    journal_title：Neurotoxicology

    pub_type： 杂志文章

    doi：10.1016/j.neuro.2015.09.004

    authors： Rauh VA,Garcia WE,Whyatt RM,Horton MK,Barr DB,Louis ED

    更新日期：2015-12-01 00:00:00

  • Further investigation of the effect of chronic ethanol on the electric membrane properties of adult DRG neurons in cell culture.

    abstract：:Neural cell cultures were used to investigate the effects of acute and chronic ethanol exposure on electric membrane properties (EMP) of adult mouse dorsal root ganglion (DRG) neurons. These results in combination with results from additional experiments involving chronic exposure to hyposomotic medium provided furthe...

    journal_title：Neurotoxicology

    pub_type： 杂志文章

    doi：

    authors： Scott B,Lew J

    更新日期：1986-04-01 00:00:00

  • Pyridoxine megavitaminosis produces degeneration of peripheral sensory neurons (sensory neuronopathy) in the dog.

    abstract：:Pyridoxine, a water-soluble vitamin, produces a sensory neuronopathy when administered in high doses to dogs. Beagles who received a daily oral dose of 300 mg/kg of pyridoxol hydrochloride developed a swaying gait within 9 days. They eventually became unable to walk, but were not weak. Animals were sacrificed at inter...

    journal_title：Neurotoxicology

    pub_type： 杂志文章

    doi：

    authors： Krinke G,Schaumburg HH,Spencer PS,Suter J,Thomann P,Hess R

    更新日期：1981-01-01 00:00:00

  • Neuroprotective effect of Valeriana wallichii rhizome extract against the neurotoxin MPTP in C57BL/6 mice.

    abstract：:Oxidative stress and inflammation are some of the contributing factors for dopaminergic neurodegeneration in Parkinson's disease (PD). Though Valeriana wallichii D.C. is known for its nervine activities its effect against PD is yet to be studied. This is the first report on the antioxidant and anti-inflammatory effect...

    journal_title：Neurotoxicology

    pub_type： 杂志文章

    doi：10.1016/j.neuro.2015.10.012

    authors： Sridharan S,Mohankumar K,Jeepipalli SP,Sankaramourthy D,Ronsard L,Subramanian K,Thamilarasan M,Raja K,Chandra VK,Sadras SR

    更新日期：2015-12-01 00:00:00

  • Multifunctional roles of zinc in Alzheimer's disease.

    abstract：:Zinc is the second abundant trace element in the human central nervous system (CNS). Zinc homeostasis is impaired in the elderly population and Alzheimer's disease (AD) patients. Due to the failures of β-amyloid (Aβ)- and microtubule-associated protein tau (MAP-tau, tau)-targeting drugs, many researchers consider AD a...

    journal_title：Neurotoxicology

    pub_type： 杂志文章

    doi：10.1016/j.neuro.2020.07.003

    authors： Xie Z,Wu H,Zhao J

    更新日期：2020-09-01 00:00:00

  • Inhibition of chloride outward transport by gadolinium in cultured rat spinal cord neurons.

    abstract：:Gadolinium is a rare-earth lanthanide metal ion and is used as organic gadolinium complexes in magnetic resonance imaging (MRI). Although gadolinium-based MRI agents are thought to be safe in clinical use, the in vivo release of the toxic free inorganic gadolinium (Gd3+) has been reported in some patients with kidney ...

    journal_title：Neurotoxicology

    pub_type： 杂志文章

    doi：10.1016/j.neuro.2008.10.003

    authors： Ishibashi H,Hirao K,Yamaguchi J,Nabekura J

    更新日期：2009-01-01 00:00:00

  • Pilot study of peripheral markers of catecholaminergic systems among workers occupationally exposed to toluene.

    abstract：:In a pilot study, serum dopamine beta-hydroxylase (DBH), platelets monoamine oxidase type B (MAO B) activities and basal plasma prolactin (PRL) were measured, among 10 workers occupationally exposed to toluene and 10 control subjects, preceding and immediately following vacation. Six exposed subjects were employed in ...

    journal_title：Neurotoxicology

    pub_type： 杂志文章

    doi：

    authors： Smargiassi A,Mutti A,Bergamaschi E,Bélanger S,Truchon G,Mergler D

    更新日期：1996-10-01 00:00:00

  • Low-level lead exposure and autistic behaviors in school-age children.

    abstract：INTRODUCTION:The association between lead exposure and autism spectrum disorder is inconclusive. We hypothesized an association between higher blood lead concentrations and more autistic behaviors, including impaired social interactions and communication, stereotypical behaviors, and restricted interests, among school-...

    journal_title：Neurotoxicology

    pub_type： 杂志文章

    doi：10.1016/j.neuro.2016.02.004

    authors： Kim KN,Kwon HJ,Hong YC

    更新日期：2016-03-01 00:00:00

  • Acute cardiorespiratory effects of intracisternal injections of mercuric chloride.

    abstract：:The present studies were conducted to changes arising from mercury poisoning in the central nervous system (CNS), with a focus on determining the receptors and neurotransmitters involved. Currently, little is known regarding the neurological basis of the cardiopulmonary effects of mercury poisoning. We evaluated chang...

    journal_title：Neurotoxicology

    pub_type： 杂志文章

    doi：10.1016/j.neuro.2011.02.006

    authors： Azevedo BF,Futuro Neto Hde A,Stefanon I,Vassallo DV

    更新日期：2011-06-01 00:00:00

  • Vanadium exposure-induced neurobehavioral alterations among Chinese workers.

    abstract：:Vanadium-containing products are manufactured and widely used in the modern industry. Yet the neurobehavioral toxicity due to occupational exposure to vanadium remained elusive. This cross-sectional study was designed to examine the neurotoxic effects of occupational vanadium exposure. A total of 463 vanadium-exposed ...

    journal_title：Neurotoxicology

    pub_type： 杂志文章

    doi：10.1016/j.neuro.2013.02.008

    authors： Li H,Zhou D,Zhang Q,Feng C,Zheng W,He K,Lan Y

    更新日期：2013-05-01 00:00:00

  • Novel cell death signaling pathways in neurotoxicity models of dopaminergic degeneration: relevance to oxidative stress and neuroinflammation in Parkinson's disease.

    abstract：:Parkinson's disease (PD) is a common neurodegenerative movement disorder characterized by extensive degeneration of dopaminergic neurons in the nigrostriatal system. Neurochemical and neuropathological analyses clearly indicate that oxidative stress, mitochondrial dysfunction, neuroinflammation and impairment of the u...

    journal_title：Neurotoxicology

    pub_type： 杂志文章,评审

    doi：10.1016/j.neuro.2009.12.003

    authors： Kanthasamy A,Jin H,Mehrotra S,Mishra R,Kanthasamy A,Rana A

    更新日期：2010-09-01 00:00:00

  • A rapid and sensitive high throughput reporter gene assay for estrogenic effects of environmental contaminants.

    abstract：:We have developed an estrogen sensitive reporter gene assay and report here on its responsiveness to steroid hormones and several estrogenic contaminants, including pesticides and polychlorinated biphenyls (PCBs), GH4C1 rat pituitary cells were stably transfected with the reported gene ERE-TK-Luc which contains a luci...

    journal_title：Neurotoxicology

    pub_type： 杂志文章

    doi：

    authors： Edmunds JS,Fairey ER,Ramsdell JS

    更新日期：1997-01-01 00:00:00

  • Methylmercury decreases IL-1beta immunoreactivity in the nervous system of the developing frog Xenopus laevis.

    abstract：:In aquatic ecosystems, mercury can become methylated and act as a potent environmental toxin, producing developmental and neurotoxic effects in a variety of species, including frogs. Molecular indicators provide a means of assessing exposure to methylmercury and for understanding how it and other environmental toxins ...

    journal_title：Neurotoxicology

    pub_type： 杂志文章

    doi：

    authors： Jelaso AM,Mackay D,Ide CF

    更新日期：1997-01-01 00:00:00

  • Type-2 alkenes mediate synaptotoxicity in neurodegenerative diseases.

    abstract：:Synaptic dysfunction appears to be an early pathogenic event in Alzheimer's disease, amyotrophic lateral sclerosis and Parkinson's disease. Although the molecular mechanism of this synaptotoxicity is not known, evidence suggests that these diseases are characterized by a common pathophysiological cascade involving oxi...

    journal_title：Neurotoxicology

    pub_type： 杂志文章,评审

    doi：10.1016/j.neuro.2008.04.016

    authors： Lopachin RM,Gavin T,Barber DS

    更新日期：2008-09-01 00:00:00