Abstract:
:Topical delivery to the various regions of the skin and underlying tissues, transdermal drug delivery and dermal exposure to environmental chemicals are important areas of research. Mathematical models of epidermal and dermal transport, involving penetration of a solute through various layers of the skin, metabolism in the skin and its subsequent distribution and clearance into systemic circulation from underlying tissues, play an essential role in this research area and are reviewed in this work.
journal_name
Adv Drug Deliv Revjournal_title
Advanced drug delivery reviewsauthors
Anissimov YG,Jepps OG,Dancik Y,Roberts MSdoi
10.1016/j.addr.2012.04.009subject
Has Abstractpub_date
2013-02-01 00:00:00pages
169-90issue
2eissn
0169-409Xissn
1872-8294pii
S0169-409X(12)00137-8journal_volume
65pub_type
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