Nitrous oxide antagonizes CNS stimulation by laudanosine in mice.

abstract：:Three anaesthetic techniques based on isoflurane were compared in outpatients undergoing laparoscopy. Sixty healthy patients were randomly allocated to receive isoflurane via mask (spontaneous respiration), via tracheal tube (spontaneous respiration) or via tracheal tube with controlled ventilation. Moderate hypercarb...

journal_title：British journal of anaesthesia

authors： Kenefick JP,Leader A,Maltby JR,Taylor PJ

更新日期：1987-02-01 00:00:00

abstract：:We present a case of pulmonary thromboendarterectomy performed successfully in a patient with stomatocytosis. Stomatocytosis is a rare condition of abnormal erythrocyte morphology in which haemolysis and hyperkalaemia occur at cooler temperatures. A 35-yr-old male with stomatocytosis was referred for pulmonary thrombo...

journal_title：British journal of anaesthesia

authors： Murali B,Drain A,Seller D,Dunning J,Vuylsteke A

更新日期：2003-11-01 00:00:00

abstract：BACKGROUND:The development of hydroxyethyl starches (HES) with low impact on blood coagulation but higher volume effect compared with the currently used HES solutions is of clinical interest. We hypothesized that high molecular weight, low-substituted HES might possess these properties. METHODS:Thirty pigs were infuse...

journal_title：British journal of anaesthesia

authors： Madjdpour C,Dettori N,Frascarolo P,Burki M,Boll M,Fisch A,Bombeli T,Spahn DR

更新日期：2005-05-01 00:00:00

abstract：BACKGROUND:Desflurane at more than 1 minimum alveolar concentration (MAC) has been shown to prolong the QT interval, but it is unclear whether this is the case at lower concentrations. The aim of this study was to determine whether desflurane concentrations of <1 MAC affect tracheal intubation-induced prolongation of t...

journal_title：British journal of anaesthesia

authors： Kim SH,Park SY,Chae WS,Jin HC,Lee JS,Kim YI

更新日期：2010-02-01 00:00:00

abstract：:We have compared the anaesthetic and analgesic efficacy of levobupivacaine with that of racemic bupivacaine in 66 male patients undergoing ambulatory primary inguinal herniorrhaphy. Patients were allocated randomly in a double-blind manner to local infiltration anaesthesia (0.25% w/v 50 ml) with either racemic bupivac...

journal_title：British journal of anaesthesia

authors： Bay-Nielsen M,Klarskov B,Bech K,Andersen J,Kehlet H

更新日期：1999-02-01 00:00:00

abstract：:The analgesic effects of an identical inguinal field block, performed before or immediately after inguinal herniorrhaphy, were evaluated in 32 healthy patients in a double-blind, randomized study. During surgery, all patients received a light general anaesthesia with thiopentone, alfentanil and nitrous oxide in oxygen...

journal_title：British journal of anaesthesia

authors： Dierking GW,Dahl JB,Kanstrup J,Dahl A,Kehlet H

更新日期：1992-04-01 00:00:00

abstract：BACKGROUND:Low bispectral index values frequently reflect EEG suppression and have been associated with postoperative mortality. This study investigated whether intraoperative EEG suppression was an independent predictor of 90 day postoperative mortality and explored risk factors for EEG suppression. METHODS:This obse...

journal_title：British journal of anaesthesia

authors： Willingham M,Ben Abdallah A,Gradwohl S,Helsten D,Lin N,Villafranca A,Jacobsohn E,Avidan M,Kaiser H

更新日期：2014-12-01 00:00:00

abstract：:Bupivacaine 2.5 mg kg-1 (0.5 ml kg-1 of 0.5% solution), with or without adrenaline 5 micrograms ml-1, was administered by interpleural injection to 12 patients after elective cholecystectomy. Noncompartmental analysis indicated that the addition of adrenaline had no effect on total body clearance, apparent volume of d...

journal_title：British journal of anaesthesia

authors： Gin T,Chan K,Kan AF,Gregory MA,Wong YC,Oh TE

更新日期：1990-06-01 00:00:00

abstract：:Although most local anaesthetic drugs are generally regarded as vasodilators at their site of injection, they produce systemic effects characterized by increases in peripheral resistance, cardiac output, arterial pressure heart rate. The direct depressive effects of the drugs are counterbalanced by increased sympathet...

journal_title：British journal of anaesthesia

authors： Blair MR

更新日期：1975-02-01 00:00:00

abstract：:We have investigated the effect of dopamine and dopexamine on the isolated perfused rat kidney. After an equilibration period of 20 min and two control periods of 10 min, dopexamine 1.0, 2.5 or 4.0 micrograms kg-1 min-1 or dopamine 2.0 micrograms kg-1 min-1 were perfused for a further 40 min in random order. Renal blo...

journal_title：British journal of anaesthesia

authors： Kirchhoff K,Leuwer M,Thum P,Bornscheuer A,Piepenbrock S

更新日期：1999-12-01 00:00:00

abstract：:A case of an infant receiving orthotopic heart transplantation with over-sized donor heart was reported. Left lower pulmonary venous obstruction after sternotomy closure was detected by transoesophageal echocardiography (TOE) and the decision to delay sternal closure was made and the clinical outcome was very satisfac...

journal_title：British journal of anaesthesia

authors： Lin CP,Chan KC,Chou YM,Wang MJ,Tsai SK

更新日期：2002-04-01 00:00:00

abstract：:The isolated rat hepatocyte model has been used to assess the hepatotoxicity of a number of i.v. anaesthetic induction agents. Ketamine, Althesin and CCI 12923 (minaxolone) all inhibited gluconeogenesis and urea formation from alanine. There was also a decrease in the cell ATP concentration, and a dose-related increas...

journal_title：British journal of anaesthesia

authors： Sear JW,McGivan JD

更新日期：1979-08-01 00:00:00

abstract：Background:Identification of statistically reliable outcomes for comparison among anaesthetists is challenging. Time-weighted intraoperative mean arterial pressure <65 mm Hg (AUC 65 ) is associated with increased odds for myocardial damage. We explored retrospectively whether such hypotension before incision was statis...

journal_title：British journal of anaesthesia

authors： Epstein RH,Dexter F,Schwenk ES

更新日期：2017-07-01 00:00:00

abstract：:We report an unusual case of acute upper airway obstruction. Inhalation of a foreign body caused choking in a 5-yr-old child, but subsequent investigations revealed a large anterior mediastinal tumour, externally compressing the trachea and the main bronchi. Such a presentation may be deceptive and is important, as ge...

journal_title：British journal of anaesthesia

authors： Akhtar TM,Ridley S,Best CJ

更新日期：1991-11-01 00:00:00

abstract：:Thirty patients for elective lower segment Caesarean section were randomly divided into two groups. One group received 50 mulitre/kg of Althesin for induction of anaesthesia and the other, 100 mulitre/kg. The two maternal groups were similar. There was no significant difference in the clinical or biochemical status of...

journal_title：British journal of anaesthesia

authors： Holdcroft A,Morgan M,Gordon H,Whitwam JG,White Y

更新日期：1975-11-01 00:00:00

abstract：:In 40 patients anaesthetized with thiopentone, 66% nitrous oxide and 1% halothane, the effects of a single i.v. dose of nalbuphine 4.5, 8, 15, 25 or 50 mg/70 kg or morphine 3, 5, 10 or 17.5 mg/70 kg on total ventilation and end-tidal carbon dioxide concentration have been measured. Depression of respiration occurred w...

journal_title：British journal of anaesthesia

authors： Klepper ID,Rosen M,Vickers MD,Mapleson WW

更新日期：1986-06-01 00:00:00

abstract：:Seventy-two adult surgical patients were studied to compare neuromuscular and cardiovascular effects of mivacurium chloride during nitrous oxide-fentanyl-thiopentone (BAL group) or nitrous oxide-halothane (HAL group) anaesthesia. Eighteen patients in the BAL group received an initial bolus of mivacurium, either the ED...

journal_title：British journal of anaesthesia

authors： From RP,Pearson KS,Choi WW,Abou-Donia M,Sokoll MD

更新日期：1990-02-01 00:00:00

abstract：:The sedation of 50 children aged 6 months to 9 years who had undergone open heart surgery was studied. During artificial ventilation a midazolam infusion was used in conjunction with the administration of morphine (and tubocurarine). Sedation for patients breathing spontaneously with positive airway pressure was conti...

journal_title：British journal of anaesthesia

authors： Booker PD,Beechey A,Lloyd-Thomas AR

更新日期：1986-10-01 00:00:00

abstract：BACKGROUND:The therapeutic potential of cardiac μ-opioid receptors in ischaemia-reperfusion (I/R) injury during opioid-modulating diseases, such as heart failure, is unknown. We aimed to explore the changes of cardiac μ-opioid receptor expression during heart failure, and its role in opioid-induced cardioprotection. M...

journal_title：British journal of anaesthesia

authors： He SF,Jin SY,Yang W,Pan YL,Huang J,Zhang SJ,Zhang L,Zhang Y

更新日期：2018-07-01 00:00:00

abstract：BACKGROUND:Whether exposure to a single general anaesthetic (GA) in early childhood causes long-term neurodevelopmental problems remains unclear. METHODS:PubMed/MEDLINE, Embase, CINAHL, Web of Science, and the Cochrane Library were searched from inception to October 2019. Studies evaluating neurodevelopmental outcomes...

journal_title：British journal of anaesthesia

authors： Ing C,Jackson WM,Zaccariello MJ,Goldberg TE,McCann ME,Grobler A,Davidson A,Sun L,Li G,Warner DO

更新日期：2021-02-01 00:00:00

abstract：BACKGROUND:The safe performance of regional anaesthesia (RA) requires theoretical knowledge and good manual skills. Virtual reality (VR)-based simulators may offer trainees a safe environment to learn and practice different techniques. However, currently available VR simulators do not consider individual anatomy, which...

journal_title：British journal of anaesthesia

authors： Grottke O,Ntouba A,Ullrich S,Liao W,Fried E,Prescher A,Deserno TM,Kuhlen T,Rossaint R

更新日期：2009-10-01 00:00:00

abstract：INTRODUCTION:In the context of an increasing number of publications of trial data analysed by Bayesian methods, clinicians need support to better understand Bayesian statistical methods. The existing checklists are intended for people who already know these methods. We aimed to establish and validate a checklist that c...

journal_title：British journal of anaesthesia

authors： Ferreira D,Barthoulot M,Pottecher J,Torp KD,Diemunsch P,Meyer N

更新日期：2020-08-01 00:00:00

abstract：:Ropivacaine is considered safer than bupivacaine, on the basis of experimental and human data that indicate a lower systemic toxicity. Here we report the occurrence of a single seizure after i.v. administration of ropivacaine 120 mg intended for extradural block in a patient having postpartum, tubal ligation. The only...

journal_title：British journal of anaesthesia

authors： Abouleish EI,Elias M,Nelson C

更新日期：1998-06-01 00:00:00

abstract：:Advances in cannabis research have paralleled developments in opioid pharmacology whereby a psychoactive plant extract has elucidated novel endogenous signalling systems with therapeutic significance. Cannabinoids (CBs) are chemical compounds derived from cannabis. The major psychotropic CB delta-9-tetrahydrocannabino...

journal_title：British journal of anaesthesia

authors： Hosking RD,Zajicek JP

更新日期：2008-07-01 00:00:00

abstract：BACKGROUND:The aim of this study was to explore difficulties at work from anaesthetists' own perspective and to examine how anaesthetists handle and cope with situations that are perceived as difficult and potentially stressful. METHODS:Two sets of interviews were conducted with 19 specialist anaesthetists in Sweden. ...

journal_title：British journal of anaesthesia

authors： Larsson J,Rosenqvist U,Holmström I

更新日期：2007-10-01 00:00:00

abstract：BACKGROUND:Lower thoracic epidural anaesthesia and analgesia (EDA) has gained increasing importance in perioperative pain therapy. The loss-of-resistance technique used to identify the epidural space is thought to rely on the penetration of the ligamentum flavum. Investigations at the cervical and lumbar regions have d...

journal_title：British journal of anaesthesia

authors： Lirk P,Colvin J,Steger B,Colvin HP,Keller C,Rieder J,Kolbitsch C,Moriggl B

更新日期：2005-06-01 00:00:00

abstract：:Day-case anaesthesia requires rapidly eliminated anaesthetics which are relatively expensive. This multinational, multicentre European study assessed the relative costs of propofol or sevoflurane anaesthesia in 211 patients. Anaesthesia was induced and maintained with propofol in group 1, with propofol and sevoflurane...

journal_title：British journal of anaesthesia

authors： Smith I,Terhoeve PA,Hennart D,Feiss P,Harmer M,Pourriat JL,Johnson IA

更新日期：1999-10-01 00:00:00

abstract：BACKGROUND:Microvascular dysfunction is considered to play an important pathophysiological role in sepsis. We addressed the hypothesis that macrovascular and microvascular flow are uncoupled in early sepsis, using a rodent model with well-characterized haemodynamic and biochemical markers of severity and subsequent mor...

journal_title：British journal of anaesthesia

authors： Dyson A,Cone S,Singer M,Ackland GL

更新日期：2012-06-01 00:00:00

abstract：BACKGROUND:Neurological deficit after repair of a thoracic or thoracoabdominal aortic aneurysm (TAA/TAAA) remains a devastating complication. The aim of our study was to investigate the clinical value of biochemical markers [S-100B, neurone-specific enolase (NSE) and lactate dehydrogenase (LD)], evoked potentials and t...

journal_title：British journal of anaesthesia

authors： Lases EC,Schepens MA,Haas FJ,Aarts LP,ter Beek HT,van Dongen EP,Siegers HP,van der Tweel I,Boezeman EH

更新日期：2005-11-01 00:00:00

abstract：:Puerperal women are reported to have a rate of cerebral infarction 13 times greater than non-pregnant females. We report a case of cerebral ischaemia in a 30-yr-old healthy parturient after epidural analgesia for labour, complicated by dural puncture treated with two epidural blood patches. Investigations showed the d...

journal_title：British journal of anaesthesia

authors： Mercieri M,Mercieri A,Paolini S,Arcioni R,Lupoi D,Passarelli F,Pinto G,Celleno D

更新日期：2003-01-01 00:00:00