Abstract：
AIMS:PET-CT scans are routinely performed in patients with lung cancer after investigation by chest x-ray (CXR) and CT scan, when these have demonstrated potentially curable disease. If the majority of patients with lung cancer potentially suitable for curative treatment could be identified earlier in the diagnostic pathway on the basis of CXR findings they could be referred for PET-CT imaging without a prior CT scan. We investigated the clinical and financial implications of adopting such a strategy. MATERIALS AND METHODS:The details of 1187 patients referred with suspected lung cancer between July 2006 and August 2009 were analysed. The initial CXR and subsequent imaging of patients fit for curative treatment (Performance Status 0/1, FEV1 > 1.0) were reviewed (n = 251). The clinical and financial implications of referring patients for first line PET-CT if deemed potentially curable based on CXR findings were assessed. RESULTS:107 of 1187 patients had potentially curable lung cancer on PS, lung function, CT and PET-CT. 96 of these 107 patients (90%) were correctly identified on CXR. 149 patients overall were diagnosed as potentially curable on CXR. Referring suitable patients for an immediate PET-CT scan resulted in a reduction in the time to complete staging investigations. CONCLUSIONS:Early PET-CT scanning for patients with suspected lung cancer, potentially suitable for curative therapy could result in more efficient staging with little additional cost.
journal_name
Clin Radioljournal_title
Clinical radiologyauthors
Macpherson R,Benamore R,Panakis N,Sayeed R,Breen D,Bradley K,Carter R,Baldwin D,Craig J,Gleeson Fdoi
10.1016/j.crad.2011.10.032subject
Has Abstractpub_date
2012-06-01 00:00:00pages
564-73issue
6eissn
0009-9260issn
1365-229Xpii
S0009-9260(12)00004-9journal_volume
67pub_type
杂志文章abstract：:Intravenous urography is the standard screening test for renovascular hypertension but there is a significant incidence of false negative and false positive results. In an attempt to improve the detection rate, indomethacin was administered orally to nine patients with renal artery stenosis (proven by arteriography an...
journal_title：Clinical radiology
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journal_title：Clinical radiology
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journal_title：Clinical radiology
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pub_type： 临床试验,杂志文章
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pub_type： 临床试验,杂志文章,多中心研究
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pub_type： 临床试验,杂志文章,随机对照试验
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abstract：:A review of imaging in the acquired immune deficiency syndrome (AIDS) is presented. The imaging features can be conveniently categorized according to whether the presenting complications are infective (bacterial, protozoal, or fungal), bronchiectasis, neoplastic (Kaposi's sarcoma, AIDS-related lymphoma, or lymphoproli...
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pub_type： 杂志文章,评审
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journal_title：Clinical radiology
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