The histological evaluation of osseointegration of surface enhanced microimplants immediately loaded in conjunction with sinuslifting in humans.

Abstract:

OBJECTIVE:The aim was to investigate histomorphometrically whether or not implant surface nanotopography improves the bone response under immediate loading simultaneous to sinus grafting. MATERIALS AND METHODS:Dual acid-etched titanium microimplants with/without crystalline surface deposition of calcium phosphate particles were placed in bilateral sinuslift areas grafted with a mixture of iliac crest bone and BioOss. Surface topography of microimplants was characterized using interferometry. Loaded microimplants (MsL) were immobilized in a provisional bridge supported by four normal size implants. Some patients had unloaded microimplants as controls (MsU). Biopsies were trephined after 2 or 4 months and histomorphometric analysis of bone area (BA) and bone-to-implant contact (BC) was performed. Nonparametric methods for dependent data were used to compare effect of surface modification, and healing time (2 vs. 4 months). RESULTS:A total of 53 biopsies were available from 13 patients. A total of 4/28 and 1/11 MsL failed after resp. 2 and 4 months vs. 0/6 and 1/5 MsU. Many loaded biopsies were damaged at the apical portion and showed no bone adhesion. MsL decreased in BA from coronal to apical from 2 to 4 months; Coronal > Middle (P = 0.047), Coronal > Apical (P < 0.001) and Middle > Apical (P < 0.001). This gradual decrease was not observed for BC; Coronal < Middle and Middle > Apical (P < 0.001). Only the middle part showed significant bone contact after 2 months. For MsL there was no statistically significant difference between surface or time indicating that improvement of osseointegration over time due to maturation of the graft was poor. The MsU did not show any difference between Osseotite and Nanotite for BIC and BA (P > 0.05) but doubled both their BA and BIC (P < 0.05) between 2 and 4 months. CONCLUSIONS:Osseointegration in sinus-grafted bone mixed with BioOss was poor irrespective of healing time or nanotopographical surface modification. The apex of MsL showed minimal bone contact suggesting that the graft does not add to the loading capacity. Surface enhancement was not beneficial despite the enlarged surface area. Overloading, most critical coronally of an implant, increases risks for implant failure and jeopardizes bone healing especially under immediate loading conditions with high load.

journal_name

Clin Oral Implants Res

authors

Browaeys H,Vandeweghe S,Johansson CB,Jimbo R,Deschepper E,De Bruyn H

doi

10.1111/j.1600-0501.2011.02398.x

subject

Has Abstract

pub_date

2013-01-01 00:00:00

pages

36-44

issue

1

eissn

0905-7161

issn

1600-0501

journal_volume

24

pub_type

杂志文章
  • The anterior loop of the inferior alveolar nerve: prevalence, measurement of its length and a recommendation for interforaminal implant installation based on cone beam CT imaging.

    abstract:OBJECTIVES:Interforaminal implant surgery requires anatomical knowledge of the area and adequate information on the location of the various landmarks of significance such as the mental foramen, the anterior loop of the inferior alveolar nerve and the mandibular incisive canal. Cone beam computed tomography (CBCT) is a ...

    journal_title:Clinical oral implants research

    pub_type: 杂志文章

    doi:10.1111/j.1600-0501.2011.02261.x

    authors: Apostolakis D,Brown JE

    更新日期:2012-09-01 00:00:00

  • An open randomized controlled clinical trial to evaluate ridge preservation and repair using SocketKAP(™) and SocketKAGE(™) : part 2 - three-dimensional alveolar bone volumetric analysis of CBCT imaging.

    abstract:OBJECTIVES:The aims of this study were (i) to evaluate the efficacy of ridge preservation and repair procedures involving the application of SocketKAP(™) and SocketKAGE(™) devices following tooth removal and (ii) to evaluate alveolar bone volumetric changes at 6 months post-extraction in intact sockets or those with fa...

    journal_title:Clinical oral implants research

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/clr.12687

    authors: Abdelhamid A,Omran M,Bakhshalian N,Tarnow D,Zadeh HH

    更新日期:2016-06-01 00:00:00

  • Resilient liner vs. clip attachment effect on peri-implant tissues of bar-implant-retained mandibular overdenture: a 1-year clinical and radiographical study.

    abstract:PURPOSE:The aim of this study was to compare between the effects of resilient liner and clip attachments of bar-implant-retained mandibular overdenture on peri-implant tissues. MATERIALS AND METHODS:In a randomized-controlled clinical trial, 30 edentulous male patients (mean age 62.5 years) were equally assigned to tw...

    journal_title:Clinical oral implants research

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/j.1600-0501.2009.01879.x

    authors: Elsyad MA,Shoukouki AH

    更新日期:2010-05-01 00:00:00

  • Immediately restored one-piece single-tooth implants with reduced diameter: one-year results of a multi-center study.

    abstract:OBJECTIVES:The aim of the present multi-center study was to evaluate the treatment outcome of immediately restored one-piece single-tooth implants with a diameter of 3 mm after 1 year. MATERIAL AND METHODS:A total of 57 one-piece implants (NobelDirect 3.0) were inserted in 47 patients (26 females, 21 males) with a mea...

    journal_title:Clinical oral implants research

    pub_type: 杂志文章,多中心研究

    doi:10.1111/j.1600-0501.2011.02174.x

    authors: Zembić A,Johannesen LH,Schou S,Malo P,Reichert T,Farella M,Hämmerle CH

    更新日期:2012-01-01 00:00:00

  • Dimensional soft tissue changes following soft tissue grafting in conjunction with implant placement or around present dental implants: a systematic review.

    abstract:OBJECTIVES:To systematically review changes in mucosal soft tissue thickness and keratinised mucosa width after soft tissue grafting around dental implants. MATERIALS AND METHODS:An electronic literature search was conducted of the MEDLINE database published between 2009 and 2014. Sequential screenings at the title, a...

    journal_title:Clinical oral implants research

    pub_type: 杂志文章,评审

    doi:10.1111/clr.12606

    authors: Poskevicius L,Sidlauskas A,Galindo-Moreno P,Juodzbalys G

    更新日期:2017-01-01 00:00:00

  • What is the impact of bisphosphonate therapy upon dental implant survival? A systematic review and meta-analysis.

    abstract:OBJECTIVE:A systematic review and meta-analysis are carried out to assess the scientific evidence that bisphosphonate therapy can decrease the success rate of dental implants. MATERIAL AND METHODS:The PubMed (Medline) database was used to search for articles published up until February 22, 2014. The meta-analysis was ...

    journal_title:Clinical oral implants research

    pub_type: 杂志文章,meta分析,评审

    doi:10.1111/clr.12526

    authors: Ata-Ali J,Ata-Ali F,Peñarrocha-Oltra D,Galindo-Moreno P

    更新日期:2016-02-01 00:00:00

  • Osseointegration of subperiosteal implant via guided tissue regeneration. A pilot study.

    abstract::The principle of guided tissue regeneration was applied in an attempt to generate bone to cover a subperiosteal implant. Titanium frame works, casted on individual impressions of the anterior surface of the tibia of 4 Copenhagen White rabbits, were stabilized to the tibia by microscrews, and half of them were covered ...

    journal_title:Clinical oral implants research

    pub_type: 杂志文章

    doi:10.1034/j.1600-0501.1995.060303.x

    authors: Hjørting-Hansen E,Helbo M,Aaboe M,Gotfredsen K,Pinholt EM

    更新日期:1995-09-01 00:00:00

  • Effect of surface topography of screw-shaped titanium implants in humans on clinical and radiographic parameters: a 12-year prospective study.

    abstract:OBJECTIVES:Although implants with a roughened surface are widely used today, little is known about the long-term effect of a roughened surface compared with the conventional machined surface on clinical and radiographic parameters. The purpose of this study is to investigate the long-term differences between moderately...

    journal_title:Clinical oral implants research

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/j.1600-0501.2009.01768.x

    authors: Vroom MG,Sipos P,de Lange GL,Gründemann LJ,Timmerman MF,Loos BG,van der Velden U

    更新日期:2009-11-01 00:00:00

  • Novel bone substitute material in alveolar bone healing following tooth extraction: an experimental study in sheep.

    abstract:OBJECTIVES:Electrospun cotton wool-like nanocomposite (ECWN) is a novel synthetic bone substitute that incorporates amorphous calcium phosphate nanoparticles into a biodegradable synthetic copolymer poly(lactide-co-glycolide). The objectives of this study were to develop a tooth extraction socket model in sheep for bon...

    journal_title:Clinical oral implants research

    pub_type: 杂志文章

    doi:10.1111/clr.12673

    authors: Liu J,Schmidlin PR,Philipp A,Hild N,Tawse-Smith A,Duncan W

    更新日期:2016-07-01 00:00:00

  • Analysis of association of clinical aspects and vitamin D receptor gene polymorphism with dental implant loss.

    abstract:UNLABELLED:Osseointegration failure is a complex, multifactorial trait shown to concentrate in some treated populations. There has been shown evidence for genetic contribution to dental implant loss. Genetic polymorphisms have been classically considered as genetic risk factors for several diseases and, more recently, ...

    journal_title:Clinical oral implants research

    pub_type: 杂志文章

    doi:10.1111/j.1600-0501.2008.01532.x

    authors: Alvim-Pereira F,Montes CC,Thomé G,Olandoski M,Trevilatto PC

    更新日期:2008-08-01 00:00:00

  • Sinus augmentation via transcrestal approach: a comparison between the balloon and osteotome technique in a cadaver study.

    abstract:BACKGROUND:The transcrestal approach with osteotomes is a commonly applied and predictable technique for maxillary sinus floor elevation. However, Schneiderian membrane perforation is a common and often inevitable intraoperative complication. Recently, the use of balloons has been proposed to reduce the risk of sinus m...

    journal_title:Clinical oral implants research

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/j.1600-0501.2012.02506.x

    authors: Chan HL,Oh TJ,Fu JH,Benavides E,Avila-Ortiz G,Wang HL

    更新日期:2013-09-01 00:00:00

  • Sinus floor elevation or referral for further diagnosis and therapy: A comparison of maxillary sinus assessment by ENT specialists and dentists using cone beam computed tomography.

    abstract:OBJECTIVES:To compare ear, nose, and throat (ENT) specialists and dentists assessing health or pathology of maxillary sinuses using cone beam computed tomography (CBCT). MATERIAL AND METHODS:Two ENT specialists and two oral surgeons assessed 100 CBCT datasets of healthy patients referred for dental implant placement i...

    journal_title:Clinical oral implants research

    pub_type: 杂志文章

    doi:10.1111/clr.13582

    authors: Janner SFM,Dubach P,Suter VGA,Caversaccio MD,Buser D,Bornstein MM

    更新日期:2020-05-01 00:00:00

  • Remodelling of sinus bone grafts according to the distance from the native bone: A histomorphometric analysis.

    abstract:OBJECTIVES:To evaluate graft remodelling according to the distance from the native bone in maxillary sinuses grafted with anorganic bovine bone (ABB). MATERIAL AND METHODS:Bilateral sinus grafting was performed in twenty patients with residual bone height <5 mm before implant placement. After 8 months, biopsy samples ...

    journal_title:Clinical oral implants research

    pub_type: 杂志文章

    doi:10.1111/clr.13639

    authors: Pignaton TB,Spin-Neto R,Ferreira CEA,Martinelli CB,de Oliveira GJPL,Marcantonio E Jr

    更新日期:2020-10-01 00:00:00

  • Impact of implant length and diameter on survival rates.

    abstract:INTRODUCTION:Despite the high success rates of endosseous oral implants, restrictions have been advocated to their placement with regard to the bone available in height and volume. The use of short or nonstandard-diameter implants could be one way to overcome this limitation. MATERIAL AND METHODS:In order to explore t...

    journal_title:Clinical oral implants research

    pub_type: 杂志文章,评审

    doi:10.1111/j.1600-0501.2006.01349.x

    authors: Renouard F,Nisand D

    更新日期:2006-10-01 00:00:00

  • Porphyromonas gingivalis biofilm formation in different titanium surfaces, an in vitro study.

    abstract:OBJECTIVE:The aim of this work was to evaluate the biofilm formation of Porphyromonas gingivalis on disks of titanium (Ti) grade 4 (G4) and Ti-6Al-4V alloy grade 5 (G5) with different surface topographies. MATERIALS AND METHODS:Porphyromonas gingivalis ATCC 33277 was used to develop an in vitro mature biofilm on a tot...

    journal_title:Clinical oral implants research

    pub_type: 杂志文章

    doi:10.1111/clr.12659

    authors: Di Giulio M,Traini T,Sinjari B,Nostro A,Caputi S,Cellini L

    更新日期:2016-07-01 00:00:00

  • Osseointegration of commercial microstructured titanium implants incorporating magnesium: a histomorphometric study in rabbit cancellous bone.

    abstract:OBJECTIVE:Recent studies have suggested that magnesium (Mg) ions exert a beneficial effect on implant osseointegration. This study assessed the osseointegration of nanoporous titanium (Ti) surface incorporating the Mg produced by hydrothermal treatment in rabbit cancellous bone to determine whether this surface would f...

    journal_title:Clinical oral implants research

    pub_type: 杂志文章

    doi:10.1111/j.1600-0501.2010.02144.x

    authors: Park JW,An CH,Jeong SH,Suh JY

    更新日期:2012-03-01 00:00:00

  • Histological and histomorphometrical evaluation of tissue reactions adjacent to endosteal implants in monkeys.

    abstract::A qualitative and quantitative histological study of the initial healing response adjacent to 24 submerged and non-submerged implants placed in the lower jaws of 6 monkeys is presented. The histomorphometric analysis showed no significant differences in mineralized bone-implant contact length between submerged and non...

    journal_title:Clinical oral implants research

    pub_type: 杂志文章

    doi:10.1034/j.1600-0501.1991.020104.x

    authors: Gotfredsen K,Rostrup E,Hjörting-Hansen E,Stoltze K,Budtz-Jörgensen E

    更新日期:1991-01-01 00:00:00

  • The influence of prophylactic antibiotic administration on post-operative morbidity in dental implant surgery. A prospective double blind randomized controlled clinical trial.

    abstract:OBJECTIVES:A prospective double-blind randomised controlled trial was conducted to test the effect of prophylactic antibiotics on post-operative morbidity and osseointegration of dental implants. MATERIALS AND METHODS:Fifty-five subjects scheduled for implant surgery were enrolled. The patients were randomly assigned ...

    journal_title:Clinical oral implants research

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/clr.12124

    authors: Nolan R,Kemmoona M,Polyzois I,Claffey N

    更新日期:2014-02-01 00:00:00

  • Characterization of the antioxidant profile of human saliva in peri-implant health and disease.

    abstract:OBJECTIVES:Peri-implant disease is considered to be an inflammatory disease, but many aspects of its pathogenesis remain unknown. At present, peri-implant disease is considered to be initiated and perpetuated by a small group of predominantly Gram-negative, anaerobic, or micro-aerophilic bacteria that colonize the subg...

    journal_title:Clinical oral implants research

    pub_type: 杂志文章

    doi:10.1111/j.1600-0501.2006.01296.x

    authors: Liskmann S,Vihalemm T,Salum O,Zilmer K,Fischer K,Zilmer M

    更新日期:2007-02-01 00:00:00

  • Biomechanical aspects of initial intraosseous stability and implant design: a quantitative micro-morphometric analysis.

    abstract:PURPOSE:The objective of this biomechanical study was to explore the effect of bone micro-morphology on initial intraosseous stability of implants with different designs. MATERIAL AND METHODS:Straumann and Astra Tech dental implants were placed into anterior and posterior regions of completely edentulous maxilla and m...

    journal_title:Clinical oral implants research

    pub_type: 杂志文章

    doi:10.1111/j.1600-0501.2006.01265.x

    authors: Akça K,Chang TL,Tekdemir I,Fanuscu MI

    更新日期:2006-08-01 00:00:00

  • An in vitro evaluation of fracture load of implant-supported zirconia-based prostheses fabricated with different veneer materials.

    abstract:OBJECTIVES:The purpose of this in vitro study was to evaluate fracture loads of implant-supported zirconia-based prostheses fabricated with different veneer materials (resin-based material and lithium disilicate ceramics). MATERIAL AND METHODS:Forty-four zirconia-based molar prostheses were fabricated on dental implan...

    journal_title:Clinical oral implants research

    pub_type: 杂志文章

    doi:10.1111/clr.13135

    authors: Takata H,Komine F,Honda J,Blatz MB,Matsumura H

    更新日期:2018-04-01 00:00:00

  • Long-term implant survival in the grafted maxilla: results of a 12-year retrospective study.

    abstract:OBJECTIVE:The aim of this study was to determine the long-term outcome of implant insertion in the augmented severely atrophied maxilla. STUDY DESIGN:Three hundred and twenty-four implants were inserted in 35 patients (eight males, 27 females, average age 57.6 years) in extremely atrophied maxillae after osteotomy and...

    journal_title:Clinical oral implants research

    pub_type: 杂志文章

    doi:10.1111/j.1600-0501.2004.01074.x

    authors: Yerit KC,Posch M,Hainich S,Turhani D,Klug C,Wanschitz F,Wagner A,Watzinger F,Ewers R

    更新日期:2004-12-01 00:00:00

  • Radiologic comparative analysis between saline and platelet-rich fibrin filling after hydraulic transcrestal sinus lifting without adjunctive bone graft: A randomized controlled trial.

    abstract:OBJECTIVES:To evaluate implant survival rate, any complications, and changes in residual alveolar bone height (RABH) using saline or platelet-rich fibrin (PRF) filling after hydraulic transcrestal sinus lifting. METHODS:Dental implants were placed after hydraulic transcrestal sinus lifting and the filling of saline (2...

    journal_title:Clinical oral implants research

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/clr.13655

    authors: Cho YS,Hwang KG,Jun SH,Tallarico M,Kwon AM,Park CJ

    更新日期:2020-11-01 00:00:00

  • Early loading of single crowns supported by 6-mm-long implants with a moderately rough surface: a prospective 2-year follow-up cohort study.

    abstract:AIM:To evaluate prospectively the clinical and radiographic outcomes after 2 years of loading of 6 mm long moderately rough implants supporting single crowns in the posterior regions. MATERIAL AND METHODS:Forty SLActive Straumann short (6 mm) implants were placed in 35 consecutively treated patients. Nineteen implants...

    journal_title:Clinical oral implants research

    pub_type: 杂志文章

    doi:10.1111/j.1600-0501.2010.01942.x

    authors: Rossi F,Ricci E,Marchetti C,Lang NP,Botticelli D

    更新日期:2010-09-01 00:00:00

  • Effect of implant-abutment connection design on reliability of crowns: regular vs. horizontal mismatched platform.

    abstract:OBJECTIVES:To evaluate the reliability and failure modes of regular and horizontal mismatched platforms for implant-abutment connection varying the implant diameter. MATERIAL AND METHODS:Regular (REG, n = 21, 4.0-mm-diameter implant) and horizontal mismatched (HM, n = 21, 4.6-mm-diameter implant) platform Ti-6Al-4V im...

    journal_title:Clinical oral implants research

    pub_type: 杂志文章

    doi:10.1111/j.1600-0501.2011.02257.x

    authors: Freitas Júnior AC,Bonfante EA,Silva NR,Marotta L,Coelho PG

    更新日期:2012-09-01 00:00:00

  • Guided bone regeneration around non-submerged implants in narrow alveolar ridges: a prospective long-term clinical study.

    abstract:OBJECTIVES:This prospective clinical study investigates long-term survival and clinical parameters of non-submerged implants with large buccal dehiscences treated with a deproteinized bovine bone mineral xenograft and a non-resorbable membrane in a one-stage approach. MATERIAL AND METHODS:Sixteen consecutive non-subme...

    journal_title:Clinical oral implants research

    pub_type: 杂志文章

    doi:10.1111/j.1600-0501.2005.01154.x

    authors: De Boever AL,De Boever JA

    更新日期:2005-10-01 00:00:00

  • New bone formation in bone defects after melatonin and porcine bone grafts: experimental study in rabbits.

    abstract:OBJECTIVE:The aim of this study was to evaluate the effect of the topical application of melatonin compared with collagenized porcine bone grafts to accelerate bone formation 2 months after their insertion in tibiae rabbits. MATERIAL AND METHODS:Twenty New Zealand rabbits weighing 3,900-4,500 g were used. Twenty colla...

    journal_title:Clinical oral implants research

    pub_type: 杂志文章,收录出版

    doi:10.1111/clr.12364

    authors: Calvo-Guirado JL,Gómez-Moreno G,Maté-Sánchez JE,López-Marí L,Delgado-Ruiz R,Romanos GE

    更新日期:2015-04-01 00:00:00

  • Osteoblast-like cells are sensitive to submicron-scale surface structure.

    abstract:OBJECTIVES:Studies showing that osteoblasts exhibit a more differentiated phenotype on rough titanium (Ti) surfaces and osteoclast-resorbed bone surfaces used materials characterized by average peak to valley distance (Ra). Other surface features impacting the cells include distance between peaks, curvature of the vall...

    journal_title:Clinical oral implants research

    pub_type: 杂志文章

    doi:10.1111/j.1600-0501.2005.01195.x

    authors: Zhao G,Zinger O,Schwartz Z,Wieland M,Landolt D,Boyan BD

    更新日期:2006-06-01 00:00:00

  • Hard tissue reaction to dual acid-etched titanium implants: influence of plaque accumulation. A histological study in humans.

    abstract:OBJECTIVES:The aim of this investigation was to evaluate histologically, histometrically, and histomorphometrically the influence of plaque accumulation on the peri-implant hard tissues. MATERIAL AND METHODS:Twelve fully edentulous subjects were selected for this investigation. Four to five standard titanium screw imp...

    journal_title:Clinical oral implants research

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1034/j.1600-0501.2003.00849.x

    authors: Kohal RJ,Bächle M,Emmerich D,Beschnidt SM,Strub JR

    更新日期:2003-08-01 00:00:00

  • The antibiotic of choice determined by antibiogram in maxillary sinus elevation surgery: a clinical study.

    abstract:OBJECTIVES:This study set out to make antibiograms of positive bacteria cultures in samples collected when performing maxillary sinus elevations to determine a specific and effective antibiotic in each case. MATERIAL AND METHODS:A total of 174 patients (90 women and 84 men) with a mean age of 55.92 years underwent 227...

    journal_title:Clinical oral implants research

    pub_type: 杂志文章

    doi:10.1111/clr.12835

    authors: Carreño Carreño J,Gómez-Moreno G,Aguilar-Salvatierra A,Martínez Corriá R,Menéndez López-Mateos ML,Menéndez-Núñez M

    更新日期:2018-11-01 00:00:00