Abstract:
BACKGROUND:The ventriculophasic response (VR) refers to shortening of atrial cycle length during heart block when a QRS complex is interposed between P waves. No formal quantitative definition has heretofore been proposed, nor have its potential clinical correlations been studied. HYPOTHESIS:We hypothesized that VR is present in selected patients who are distinguished by clinical features from those who lack VR. METHODS:Pacing devices were temporarily programmed to VVI mode at 30 ppm as electrocardiogram and intracardiac electrograms were recorded at 50 mm/sec paper speed. We measured the percentage decrease in a P-P interval (A-A interval on the atrial electrogram) containing a QRS, compared to the preceding P-P interval. Left ventricular ejection fraction (LVEF) was measured by echocardiogram. RESULTS:Shortening of P-P interval was observed chiefly when the interposed QRS occurred early in the anticipated P-P interval (as judged by the preceding P-P interval). P-P shortening of 0% to 3% occurred randomly. Defining VR as being a >3% P-P interval shortening when an interposed QRS occurred in the first 60% of the anticipated P-P interval, we found that VR was present in 28 (55%) of our patients. It was quite reproducible, was more common in women (81% vs 37% of men; P = 0.004), and positively correlated with LVEF (r = 0.41, P = 0.004). It did not correlate with age, diabetes, or β-blocker use. CONCLUSIONS:Using our newly derived definition of VR, we found the phenomenon was present in 55% of our patients. It was reproducible and more commonly seen in women and patients with LVEF ≥40%.
journal_name
Clin Cardioljournal_title
Clinical cardiologyauthors
Dadu RT,McPherson CAdoi
10.1002/clc.20998subject
Has Abstractpub_date
2012-01-01 00:00:00pages
21-5issue
1eissn
0160-9289issn
1932-8737journal_volume
35pub_type
杂志文章abstract::A fulminant psychiatric disturbance, as the sole noncardiac manifestation of digitalis toxicity, emerged in a 85-year-old woman during treatment for congestive heart failure. Described more than a century ago as "digitalis delirium," the disorder is characterized by severe agitation, delusional thinking, assaultive be...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960180611
更新日期:1995-06-01 00:00:00
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journal_title:Clinical cardiology
pub_type: 杂志文章,评审
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pub_type: 杂志文章,评审
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更新日期:2008-09-01 00:00:00
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journal_title:Clinical cardiology
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journal_title:Clinical cardiology
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journal_title:Clinical cardiology
pub_type: 杂志文章,评审
doi:10.1002/clc.4960180506
更新日期:1995-05-01 00:00:00
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journal_title:Clinical cardiology
pub_type: 杂志文章,评审
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更新日期:1997-08-01 00:00:00
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journal_title:Clinical cardiology
pub_type: 杂志文章,评审
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journal_title:Clinical cardiology
pub_type: 杂志文章,多中心研究
doi:10.1002/clc.22810
更新日期:2017-12-01 00:00:00
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pub_type: 社论
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更新日期:2003-04-01 00:00:00
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journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960190711
更新日期:1996-07-01 00:00:00
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pub_type: 临床试验,杂志文章
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更新日期:1999-05-01 00:00:00
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pub_type: 杂志文章,评审
doi:10.1002/clc.4960230804
更新日期:2000-08-01 00:00:00
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journal_title:Clinical cardiology
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1002/clc.4960170107
更新日期:1994-01-01 00:00:00
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journal_title:Clinical cardiology
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pub_type: 杂志文章
doi:10.1002/clc.4960280109
更新日期:2005-01-01 00:00:00
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journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960180713
更新日期:1995-07-01 00:00:00
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journal_title:Clinical cardiology
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doi:10.1002/clc.4960151017
更新日期:1992-10-01 00:00:00
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journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960170610
更新日期:1994-06-01 00:00:00
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pub_type: 杂志文章
doi:10.1002/clc.4960240716
更新日期:2001-07-01 00:00:00
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pub_type: 杂志文章
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更新日期:2005-02-01 00:00:00
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更新日期:2018-06-01 00:00:00
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journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960150409
更新日期:1992-04-01 00:00:00