Abstract:
:The pandemic influenza (H1N1) 2009 raised a number of issues, of which we address the following: Why did between 25 and 30% of severe influenza cases show no obvious risk factor? We hypothesize that an element that can contribute to the answer are host genetic risk factors involved in poor disease progression. Several indications led us to this hypothesis: i) studies of familial aggregation in Iceland and Utah Mormons show some heritability of influenza mortality; ii) nearly 300 known human genes are necessary for the replication of the influenza virus, and iii) the most severe cases of influenza A (H1N1) 2009 showed a deregulation of the adaptive immune system. We are addressing this problem through a case-control design (hospitalized cases of influenza (H1N1) 2009 confirmed against outpatient cases, also confirmed for (H1N1) 2009), which will be genotyped for more than a million single nucleotide polymorphisms (SNPs) and copy number variations (CNVs).
journal_name
Rev Esp Salud Publicajournal_title
Revista espanola de salud publicaauthors
Calafell i Majó F,González Candelas Fdoi
10.1590/S1135-57272011000100004subject
Has Abstractpub_date
2011-01-01 00:00:00pages
33-6issue
1eissn
1135-5727issn
2173-9110pii
S1135-57272011000100004journal_volume
85pub_type
杂志文章abstract:OBJECTIVE:Nowadays, after licensure of the second generation new pneumococcal conjugate vaccines (PCV10/PCV13). The epidemiology of the pneumococcal disease must be re-evaluated. The present study described incidence, lethality and serotype distribution of invasive pneumococcal disease (IPD) in the general population o...
journal_title:Revista espanola de salud publica
pub_type: 杂志文章
doi:
更新日期:2018-10-02 00:00:00
abstract:BACKGROUND:This study is aimed at establishing the possible associations between the number of admissions through the emergency room at the "Juan Canalejol" Hospital in Corunna in 1994-1994 due to organic, circulatory and respiratory reasons and the weather variables introduced as being exogenous for the purpose of pre...
journal_title:Revista espanola de salud publica
pub_type: 杂志文章
doi:
更新日期:1999-01-01 00:00:00
abstract:OBJECTIVE:The Spanish registry of Covid-19 in Spanish pregnant women, made up of 100 centers, is created in response to the need to know the morbidity that Covid-19 generates in pregnant women and their newborns, to know the real incidence of the disease in this population group and to establish and monitor the package...
journal_title:Revista espanola de salud publica
pub_type: 杂志文章
doi:
更新日期:2020-09-18 00:00:00
abstract:OBJECTIVE:The European Commission recommends ensuring equity in cancer screening. The aim of this study was to find out if there were inequalities in access to cancer screening programmes in Spain. METHODS:A transversal study was carried out by means of a survey addressed to the people responsible for breast, colorect...
journal_title:Revista espanola de salud publica
pub_type: 杂志文章
doi:
更新日期:2021-01-26 00:00:00
abstract:BACKGROUND:Most patient classification systems have been designed in the United States for the purpose of availing of a tool providing a means of gauging the use of resources. This study was aimed at calculating the mean relative weights (MRW's) for the cost of care at several primary care health facilities as compared...
journal_title:Revista espanola de salud publica
pub_type: 杂志文章
doi:10.1590/s1135-57272006000100006
更新日期:2006-01-01 00:00:00
abstract:BACKGROUND:The purpose of this work is to analyze the fertility of the hydatid cysts from ovine, animal species of great epidemiological interest in the hydatid disease, and the ability of the gerbil (Meriones unguiculatus) as model experimental for the study "in vivo" of this hidatyd disease as preliminary phase of th...
journal_title:Revista espanola de salud publica
pub_type: 杂志文章
doi:
更新日期:1997-09-01 00:00:00
abstract:BACKGROUND:To identify epidemiological aspects of the osteoporotic hip fractures (OHF) in the province of Zamora in 1993, and the basic and standardised accumulative incidence rates amongst the Spanish population. METHODS:215 OHF cases were studied in the province throughout 1993, 203 were admitted to hospital, 188 of...
journal_title:Revista espanola de salud publica
pub_type: 杂志文章
doi:
更新日期:1997-07-01 00:00:00
abstract:BACKGROUND:The Hospital Morbidity Survey (EMH) includes, at the moment, 85% of hospitals and 90% of discharges, and is the only national data source that allows to deepen with information about diagnostics, gender or age, in the study of hospitals as place of death. This work aims to analyze the presence of inhospital ...
journal_title:Revista espanola de salud publica
pub_type: 杂志文章
doi:10.1590/s1135-57272008000600010
更新日期:2008-11-01 00:00:00
abstract:BACKGROUND:There are recommendations to prevent falls. Our goal is to determine, in older people, the knowledge and adherence to these recommendations, and to analyze the demographic characteristics and associated morbidity. METHODS:Observational study of prevalence and crossed association. The target population are o...
journal_title:Revista espanola de salud publica
pub_type: 杂志文章
doi:
更新日期:2010-07-01 00:00:00
abstract::The precautionary principle is a response to uncertainty in the face of risks to health or the environment. In general, it involves taking measures to avoid potential harm, despite lack of scientific certainty. In recent years it has been applied, not without difficulties, as a legal and political principle in many co...
journal_title:Revista espanola de salud publica
pub_type: 杂志文章,评审
doi:10.1590/s1135-57272005000200003
更新日期:2005-03-01 00:00:00
abstract:OBJECTIVE:In the last decade, public policy makers are applying new tools to promote healthy habits, starting from the behavioral economics sciences and social psychology. These tools are known as nudges, and before being applied, the degree of acceptance that the population presents about them must be analyzed. The ob...
journal_title:Revista espanola de salud publica
pub_type: 杂志文章
doi:
更新日期:2020-07-24 00:00:00
abstract:BACKGROUND:The implementation of an information system on prescription drug plan that includes the pharmacological classification and the composition of the drugs. In addition to economic data, makes it possible to analyze prescriptions from a pharmacotherapeutic and economic perspective and, accordingly, carry out adm...
journal_title:Revista espanola de salud publica
pub_type: 杂志文章
doi:
更新日期:1995-05-01 00:00:00
abstract:BACKGROUND:Social inequality in health is an increasing phenomenon in the world. The aim was to compare in 2002 and 2012, the magnitude of inequalities in leisure-time physical inactivity by educational level in Spain, but also the trends in health perception, in physically inactive people. METHODS:A cross-sectional s...
journal_title:Revista espanola de salud publica
pub_type: 杂志文章
doi:10.4321/S1135-57272015000300004
更新日期:2015-05-01 00:00:00
abstract:BACKGROUND:In undertaking a Minimum Basic Data Set (MBDS) of hospital discharges has to be done for all hospitals. It depends on the good function of the Medical Records Archive. The objective of this study is the continuous evaluation of the quality of the Medical Records Archive via Control Diagrams statistical techn...
journal_title:Revista espanola de salud publica
pub_type: 杂志文章
doi:10.1590/S1135-57272011000400008
更新日期:2011-08-01 00:00:00
abstract:BACKGROUND:Anxiety, dissociative and somatoform disorders (WHO-e 300) are the second cause of Temporary Disability (TD) in Spain. This is the main reason that justifies the analysis of the variability among primary health care centers (PHC) of the Valencian Community in the prescription processes of Temporary Disabilit...
journal_title:Revista espanola de salud publica
pub_type: 杂志文章
doi:10.1590/S1135-57272012000100006
更新日期:2012-01-01 00:00:00
abstract:OBJECTIVE:To evaluate preventive interventions on alcohol consumption has been long recommended in Spain. The impact evaluation of structured programs and specific actions for the prevention and treatment of alcohol consumption (PAPTCA) would allow making better informed decisions on public health financing based on th...
journal_title:Revista espanola de salud publica
pub_type: 杂志文章
doi:
更新日期:2020-06-18 00:00:00
abstract:BACKGROUND:Calcium supplements and vitamin D are involved in current debates of health, as cardiovascular safety of calcium, and correction of vitamin levels. The aim is to review the possibilities of making better use of supplements marketed in Spain, depending on their availability, information and related epidemiolo...
journal_title:Revista espanola de salud publica
pub_type: 杂志文章,评审
doi:10.4321/S1135-57272012000500002
更新日期:2012-10-01 00:00:00
abstract:BACKGROUND:On the 4th of February 2008, 2 cases of measles, epidemiologically linked (2 members of the crew of the Fast-Ferry Jaime I from the company Balearia, which performs the route Algeciras-Tangier), were notified to the Epidemiological Surveillance Network in Andalusia (SVEA). The aim of this paper is to epidemi...
journal_title:Revista espanola de salud publica
pub_type: 杂志文章
doi:10.1590/s1135-57272010000200007
更新日期:2010-03-01 00:00:00
abstract::This study analyses the historical background data on Spanish community nutrition by means of the study of the first attempts toward institutionalization which took place in the Nutrition and Food Hygiene Division of the Spanish National Health School, restricting the search to the 1930-1936 period. In conjunction wit...
journal_title:Revista espanola de salud publica
pub_type: 历史文章,杂志文章
doi:10.1590/s1135-57272007000500003
更新日期:2007-09-01 00:00:00
abstract:BACKGROUND:Non-lineal temperature-mortality relationship varies depending on the characteristics of the designated study geographic zone. In given places, a growing level of economic development has led to lesser influence of environmental variables on mortality. This paper analyzes trends in the association between ma...
journal_title:Revista espanola de salud publica
pub_type: 杂志文章
doi:10.1590/s1135-57272007000400005
更新日期:2007-07-01 00:00:00
abstract:OBJECTIVE:In the month of April 2017, two cases of measles were reported in one of the basic health zones (ZBS) of the Region of Murcia. The Occupational Risk Prevention Services of the Murcian Health Service (SMS) were urged to review the immunological status of health workers, born as of 1971, from Primary Care Cente...
journal_title:Revista espanola de salud publica
pub_type: 杂志文章
doi:
更新日期:2019-03-05 00:00:00
abstract::We present the adaptation for Spain of the updated European Cardiovascular Prevention Guidelines. In this update, greater stress is laid on the population approach, and especially on the promotion of physical activity and healthy diet through dietary, leisure and active transport policies in Spain. To estimate vascula...
journal_title:Revista espanola de salud publica
pub_type: 杂志文章
doi:
更新日期:2020-09-11 00:00:00
abstract:BACKGROUND:The displacement of populations as the result of an armed conflict generally entails a worsening of the living and health conditions of those undergoing such a displacement. This paper is aimed at analyzing the health-related needs perceived by men and women displaced by the armed conflict and their main str...
journal_title:Revista espanola de salud publica
pub_type: 杂志文章
doi:
更新日期:2003-03-01 00:00:00
abstract:OBJECTIVE:Among the lesions produced by the professional use of the voice since 2007, the Vocal Nodules (VN) are recognized in Spain as an Occupational Disease. With the aim of promoting its notification in Navarre, the Sentinel Program was incorporated in 2013 and, with this study, we seek to verify its efficacy. MET...
journal_title:Revista espanola de salud publica
pub_type: 杂志文章
doi:
更新日期:2017-07-07 00:00:00
abstract:OBJECTIVE:The partner notification is one of the main activities of epidemiological surveillance in Public Health. The primary objective was to estimate the compliance of the partner notification by health professionals who reported sexually transmitted diseases (HIV, Gonorrhoea, Syphilis and Chlamydia) during 2017 in ...
journal_title:Revista espanola de salud publica
pub_type: 杂志文章
doi:
更新日期:2019-12-02 00:00:00
abstract:BACKGROUND:Regular physical exercise is not a widespread habit among the population. Early childhood in a crucial stage for acquiring this habit. The objective of this study was that of ascertaining the behavior of school-age children with regard to the degree of physical activity they do and to examine the factors inv...
journal_title:Revista espanola de salud publica
pub_type: 杂志文章
doi:
更新日期:1998-05-01 00:00:00
abstract:OBJECTIVE:Terminal patients and their relatives must know their real situation, and be treated according to the principle of autonomy, to establish therapeutic objectives adapted each one, according to their needs and decisions. The objective of this study is to identify the sufficient existence of records in the Medic...
journal_title:Revista espanola de salud publica
pub_type: 杂志文章
doi:
更新日期:2020-05-05 00:00:00
abstract:BACKGROUND:the prevalence of chronic viral hepatitis in Spain could vary because of the immigrants coming from countries having an elevated with a higher endemicity of hepatitis B and C virus. Hepatitis B and hepatitis C virus infections are an important health problem worldwide taking into account their chronic conseq...
journal_title:Revista espanola de salud publica
pub_type: 杂志文章,评审
doi:10.4321/S1135-57272014000600012
更新日期:2014-11-01 00:00:00
abstract:BACKGROUND:The aim of this study was to analyze the impact on tobacco consumption among working population of the Law 42/2010, which amends smoking regulations in Spain. METHODS:Data were obtained from 413,473 Occupational Health check-ups, conducted between July of 2009 and June of 2011, in the Society for Prevention...
journal_title:Revista espanola de salud publica
pub_type: 杂志文章
doi:10.1590/S1135-57272012000200006
更新日期:2012-03-01 00:00:00
abstract::Falls in the elderly are a serious problem that results in large health care expenditures. To prevent them, it has been shown that the key is an epidemiologic knowledge of the target population. The purpose of this systematic review was to identify the incidence, risk factors and consequences of falls in the Spanish p...
journal_title:Revista espanola de salud publica
pub_type: 杂志文章,评审
doi:10.1590/s1135-57272008000100004
更新日期:2008-01-01 00:00:00